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Transcript
Junctional Ectopic Tachycardia (JET) Care Guideline
for Cardiovascular Intensive Care Unit (CVICU)
Inclusion Criteria: Postoperative Cardiac Surgical Patient.
Diagnosis of JET confirmed by EKG. Patient must have
hemodynamic instability due to the arrhythmia.
Exclusion Criteria: Patients without temporary pacing wires.
Initial Management
Adequate sedation
Electrolytes (especially magnesium)
Temperature 36-37 degrees rectal
Decrease vasoactives (especially dopamine)
Recommendations/
Considerations
GOAL of treatment is to decrease JET
Attempt brief period of atrial pacing over ventricular rate
Check threshold of wires
rate just low enough to pace over
● Lower doses may be appropriate in
preterm neonate or impaired renal
function
Obtain atrial ECG to document rhythm
Obtain ECHO to rule out effusion and check function
Notify Cardiologist
Secondary Medications/Interventions
Frequently reassess rhythm to determine ongoing need for medication
Consider cooling patient further down to 35-36 degrees rectal
Dexmedetomidine infusion start at 0.2 mcg/kg/hr up to max of 1 mcg/kg/hr.
● Reserve dexmedetomine load for extreme situations
● Amiodarone 1 mg/kg over 10 minutes. Repeat in 1 mg/kg increments to a total
dose of 5 mg/kg
● Then amiodarone infusion at 5 mcg/kg/min.
● Give intravenous CaCl prior to amiodarone load
Consider EP consult if patient
does not respond to first
pharmacologic agent
● Procainamide 7-10 mg/kg load over 30 minutes
● Then procainamide infusion at 40-60 mcg/kg/min
● Check levels at 4 hours
● Use with caution if ejection fraction already decreased
● Esmolol infusion at 50-300 mcg/kg/min
● Consider loading with caution
● Consider esmolol as first line agent in patients with JET presenting on
POD 2 or greater and the patient is not on dopamine and ejection
fraction is normal
Approved EBM Committee 1-20-2016
Reassess the appropriateness of Care Guidelines as condition changes. This guideline is a tool to aid clinical decision making. It is
not a standard of care. The provider should deviate from the guideline when clinical judgment so indicates
References for Junctional Ectopic Tachycrdia (JET)
Care Guideline
Andreasen, J.B., S.P. Johnson, and H.B. Ravn, Junctional ectopic tachycardia after surgery for congenital heart disease in children.
Intensive care medicine, 2008. 34(5): p. 895-902.
Batra, A.S., et al., A prospective analysis of the incidence and risk factors associated with junctional ectopic tachycardia following
surgery for congenital heart disease. Pediatric cardiology, 2006. 27(1): p. 51-5.
Chrysostomou, C., et al., Dexmedetomidine: a novel drug for the treatment of atrial and junctional tachyarrhythmias during the
perioperative period for congenital cardiac surgery: a preliminary study. Anesthesia and analgesia 2008. 107(5): p. 1514-22.
Dodge-Khatami, A., et al., Impact of junctional extopic tachycardia on postoperative morbidity following repair of congenital heart
defects. European journal of cardio-thoracic surgery: official journal of the European Association for Cardio-thoracic Surgery, 2002.
21(2): p. 255-9.
Dodge-Khatami, A., et al., Surgical substrates of postoperative junctional ectopic tachycardia in congenital heart defects. The
Journal of thoracic and cardiovascular surgery, 2002. 123(4): p. 624-30.
Dorman BH, et al. Magnesium supplementation in the prevention of arrhythmias in pediatric patients undergoing surgery for
congenital heart defects. Am H J 2000; 139:522-8.
Grosse-Wortmann, L., et al., Prevalence of and risk factors for peri-operative arrhythmias in neonates and children after
cardiopulmonary bypass: continuous holter monitoring before and for three days after surgery. Journal of cardiothoracic surgery,
2010. 5: p. 85.
Hoffman, T.M., et al., Postoperative junctional ectopic tachycardia in children: incidence, risk factors, and treatment. The
Annals of Thoracic Surgery, 2002. 74(5): p. 1607-11.
Kendrick JG, et al. Amiodarone treatment of junctional ectopic tachycardia in a neonate receiving extracorporeal membrane
oxygenation. Ann Pharmacother 2006;40:1872-5.
Kovacikova L, et al. Amiodarone as a first line therapy for postoperative junctional ectopic tachycardia. Ann Thor Surg 2009;
88:616-22.
Manrique, A.M., et al., Magnesium supplementation during cardiopulmonary bypass to prevent junctional ectopic tachycardia
after pediatric cardiac surgery: a randomized controlled study. The Journal of thoracic and cardiovascular surgery, 2010. 139(1):
p. 162-169 e2.
Mildh, L., et al., Junctional ectopic tachycardia after surgery for congenital heart disease: incidence, risk factors and outcome.
European journal of cardio-thoracic surgery: official journal of the European Association for Cardio-thoracic Surgery, 2011. 39(1):
p. 75-80.
Perry JC, et al. Pediatric use of intravenous amiodarone: efficacy and safety in critically ill patients from a multicenter protocol. J
Am Coll Cardiol 1996; 27:1246-50.
Saul JP, et al. Intravenous amiodarone for incessant tachyarrhythmias in children: a randomized, double-blind anti-arrhythmic
drug trial. Circulation 2005; 112:3470-7.
Walsh EP, et al. Evaluation of a staged treatment protocol for rapid automatic junctional tachycardia after operation for congenital
heart disease. J AM Coll Cardiol 1997;29:1046-53.