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Male Reproductive System I Can describe the structure and function of the male reproductive system including the following: • • • • • • • • • • • Testes Seminiferous tubules Interstitial cells Epididymis Vas deferens, Cowper`s gland Seminal vessicles Prostate gland Ejaculatory duct Urethra Penis Review of Sexual Reproduction • Both parents donate ________ material • Offspring will be different than parents and each other • More _________ in sexual reproduction than asexual – A parent cell divides to create two cells that are identical to one another and parent Male Anatomy • Male and female sex organs originate in the __________ cavity • During the ________ month the genes of the sex chromosomes cause differentiation • Testes descend through a canal in the scrotum Urinary Bladder • • Sphincter regulates the voiding of fluid from the bladder Ureter • Carries ______ from the ________ to the urinary bladder Scrotum • Pouch of skin below the pelvis that contains the ______ • Keeps testicles ______ to allow ________ of sperm • Descend through small canal from abdominal cavity to scrotum during the last two months in utero • Membrane of skin forms over canal preventing testes from re-entering abdominal cavity Scrotal Abnormalities • Deformities: – ___________________ • Testes fail to drop from body cavity • Abdominal cavity too warm to produce ______ sperm; man is sterile – Inguinal hernia • Membrane separating abdominal cavity from scrotum gets ruptured, ___________ can be forced into _________ • Blood flow of testes and small intestine in danger due to pressure – Ruptured Testicle • Forceful, direct blow • _____% from sports related injuries • If treated within 72 hours, 80% chance of salvaging damaged testicle u y Testes • Male gonads • • Produce sex cells (sperm) in coiled seminiferous tubules Seminiferous Tubules • Housed in the testes, which are about 5 cm long. • If uncoiled, they would measure _____m • Lined with spermproducing cells called ______________ • Site of spermatogenesis, or the _________ of sperm cells Epididymus • Tightly coiled tube connecting the ________________ to the ________________ where sperm are mature and become motile Vas Deferens • Tube that conducts sperm towards the _______ • Carries sperm from the testis to the ejaculatory duct Ductus Deferens • A storage duct that carries sperm and fluids (semen)from the epididymis to the ejaculatory duct Ejaculatory Duct • A tubule formed where the vas deferens and seminal vessicle ducts meet, opens into _______ • Stores the sperm from vas deferens until needed • Propels the movement of semen into the urethra Urethra • A duct, shared by the urinary and reproductive systems, that carries fluid through the penis • At any time, urethra conducts either urine or semen, Penis • Used to transfer sperm from the male to the female reproductive tract • Glans Penis – Foreskin • A flap of skin that protects the surrounds and protects the glans penis • The tissue that is removed during _____________ Semen • Secretion consisting of sperm and fluids • ~1 tsp produced during ejaculation which contains roughly ______ million sperm • 2-3% sperm, remaining is seminal fluid Vasectomy • Common procedure to prevent pregnancy • Vas deferens from each testicle is _____________ • Performed at Dr’s office with a _______ anesthetic Success Rates of Birth Control Method Used By Type Dr Rx? Actual Failure Rate Reversible Abstinence Both M & F Natural No 0.0% Yes Condom Male Barrier No 1-33% Yes Hormone Implant Female Hormonal Yes 0.2% Yes No method Both M & F - No >85% -- Oral Female Hormonal Yes 0.16-3% Yes Vasectomy Male Surgical Yes 0.02-0.2% Possibly Withdrawal Male Natural No 19% Yes Adapted from Adapted from: 1. Trussell J, Hatcher RA, Cates W, Stewart FH, Kost K. A Guide to Interpreting Contraceptive Efficacy Studies. Obstetrics and Gynecology 1990; 76:558-67. 2. Mishell DR, Jr. Contraception. New England Journal of Medicine 1989; 320: 777-787. The Glands • • • • Seminal vessicle Prostate gland Cowper`s gland Responsible for nourishing and lubricating sperm • Part of the endocrine system Seminal vesicles • Produces a mucouslike fluid containing ________ (sugar) which provides _______ for sperm Prostate gland • Produces mucus-like alkaline fluid that neutralizes the ______ from ______ in the urethra Cowper’s gland • Secretes alkaline mucuslike fluids into the urethra Can you...? • Identify the following structures on the diagram – – – – – – – – – – – – Cowper`s gland Prostate gland Vas deferens Ejaculatory duct Urethra Seminal vessicles Seminiferous tubule Epididymus Testicles Scrotum Penis Glans penis • Sexual arousal: • _______________ nerve causes arteries leading to the penis to _______, increasing blood flow • Spongy tissue of the penis swells, _____________ veins that carry blood away from the penis • Penis engorges with blood and becomes erect Spermatogenesis 1. Spermatogonia (______________________) divide to form spermacytes 2. Spermacytes differentiate into spermatids • Spermatids – – Contain only __ chromosomes (half as much as other cells) – 9-10 weeks to differentiate into sperm cell Spermatogenesis 3. Sertoli cells found in the seminiferous tubules ________ the developing sperm cells to maturity • Sertoli cells – Provide a _______ between blood and testes – Barrier controls the entry/exit of hormones, nutrients; ________ the sperm cells – If barrier is damaged, body develops antibodies against its own sperm Spermatogenesis 4. Sperm mature in the epididymis; defective sperm are ________ here by the __________ system Sperm • Swimming motion begins after __ days in the epididymis • Streamlined design (reduced cytoplasm) for motion • Limited cytoplasm = _________________ • Mitochondria found between the nucleus and the flagellum (propulsion) • Acrosome-cap on head of sperm cell, filled with ________ that dissolve the outer coating of the egg Seminal Fluid • Ejaculation is the process where semen leaves a man body through the penis • Sperm is forced to the base of the penis by the ___________ of the vas deferens, seminal vesicles, ejaculatory duct and prostate gland • Strong muscular contractions force the semen into the urethra and out the penis Seminal Fluid • Seminal vesicles – Release fluid containing fructose and prostaglandins • Fructose-energy supply • Prostaglandins-stimulate rhythmic contractions of smooth muscle along the female reproductive tract • Prostate gland – Secretes an alkaline buffer that protects sperm from acidic environment of vagina • Cowpers gland – Secretes mucus-rich fluid prior to ejaculation – Protects sperm from acids in the urethra – May help with sperm motility Affect of Hormones on Male System • Primary sexual characteristics – Physical characteristics of an organism that are directly involved in reproduction – • Secondary sexual characteristics – ________ features other than reproductive organs, that indicate gender Testosterone • Primary male sex hormone produced in insterstitial cells of testes • Triggers ___________ of tests and penis, as well as spermatogenesis • Promotes secondary characteristics – – Growth of larynx (deepening voice) – Strengthening of muscles – • __________ and _________ control production of sperm and sex hormones • Pituitary- produces and stores gonadotropic hormones (gonadotropins) which regulate the testes • 2 gonadotropins – • Turns on production of sperm cells in seminiferous tubules – • Promotes production of testosterone by interstitial cells Male Reproductive Hormones Hormone Location Function Pituitary gland Triggers production of sperm cells in seminiferous tubules Interstitial cells Luteinizing hormone Stimulates secretion of FSH and LH • Negative feedback systems ensure that sperm cells and testosterone are maintained at constant levels • When testosterone is low: – – – – – – Hypothalamus secretes _____ GnRH activates pituitary gland to release _____ and L____ FSH acts on sperm-producing cells in seminiferous tubules LH stimulates __________ production Testosterone stimulates ____________ Negative feedback regulates LH and testosterone • High testosterone _________ LH production directly by feedback inhibition of LH release from the pituitary and indirectly from GnRH release from the hypothalamus • When hypothalamus detects _____ testosterone, releases less GnRH, which leads to less LH • Decreased GnRH slows down LH, which means lower testosterone