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Carlton le Willows learning cycle – GCSE Combined Science (Triple Biology) Year 10 Spring Term learning cycle 3 Topic Inheritance Overarching CCQ How do I inherit my characteristics from my parents? Knowledge / skills areas Compare and contrast asexual and sexual reproduction Describe in outline the stages in meiosis and explain how it brings about variation Describe the structure of DNA Describe the layout of genes, chromosomes and the genome as a whole Describe the impact of the Human Genome Project Be able to extract DNA from fruit Describe the process of information transfer from DNA to proteins (Higher) Explain how changes to the strength of a promoter affect transcription (Higher) and how changes within a gene affect phenotype (Higher) Explain how characteristics are inherited, including gender. Understand the terms co-dominance and the effect of multiple alleles. Explain the inheritance of sex-linked traits (Higher) Explain the causes of variation within a population and understand that most mutations have little or no effect on phenotype Lesson specific CCQs Why do some organisms reproduce using sex while others do not? Why are my brothers and sisters different from me? How can the structure of DNA bring about inheritance? What is my genome and what does it do? How can I get DNA from cells? How do my genes determine my characteristics? Why doesn’t all of my DNA code for proteins? Why did Mendel spend so much time with peas? What is a pedigree diagram? Why have I got blood group AB? Why do only boys get Duchene Muscular Dystrophy? Will mutations turn us into X-men? Vocabulary scaffolding Sexual reproduction; mate; asexual reproduction; clone; reproductive cycle; meiosis; haploid; variation; double helix, complimentary base pair; sugar-phosphate; hydrogen bond; RNA polymerase (H); (Promoter) (H); non-coding DNA; (H) coding DNA (H); transcription (H); translation (H); ribosome (H); tRNA (H); mRNA (H); amino acid (H); codon (H); anticodon (H); polypeptide (H); genetics; inheritance; allele; co-dominant; recessive; dominant; se-linked (H); monohybrid; Punnett Square; probability, ratio and percentage; ABO blood group; variation; mutation Character pillar links During this topic the following character pillar/s will be discussed: Curiosity, determination Home study tasks Task description Deadline PROJECT: Fragile X, Huntington’s Disease and Friedreich's ataxia are all associated with changes to gene structure but in slightly different ways. Describe these changes. Note: that this is challenging project which will really test your understanding. Set by class teacher. Learn the spellings for each of the keywords and consider how you would use each word in a sentence. Set by class teacher. Revise for tests and exams. Progress assessments Carlton le Willows learning cycle – GCSE Combined Science (Biology) Year 10 Spring Term learning cycle 4 Topic Evolution through Natural Selection Overarching CCQ Is Natural Selection “enough”? Knowledge / skills areas Describe the roles of Darwin and Wallace in developing the idea of Evolution through Natural Selection. Explain the process of natural selection with reference to examples in nature. How has the human species evolved? What are stone tools and how can they be used to chart human evolution? What is a pentadactyl limb and what does it tell us about animal evolution? How did 5 kingdoms become 3 domains? What is selective breeding? How can we use tissue culture to generate new plants and animals? The production of insulin by bacteria using genetic engineering. (Higher.) What are the advantages and disadvantages of using GMOs? What are we doing to improve food security? What are the risks of GMOs and selective breeding programmes in agriculture and medicine? Lesson specific CCQs What is evolution through natural selection? How did the theory of evolution come about? How do we know evolution through natural selection is true? How have humans evolved and what is the evidence for this? Why do the vertebrates limbs have the same , overall structure? Vocabulary scaffolding Evolution; natural selection; drug resistance; malaria resistance; Ardi, Lucy; Turkana Boy; relative dating; pentadactyl limb; biological domains and biological kingdoms; selective breeding; genetic engineering; genetically-modified organism; (sticky end; restriction enzyme; DNA ligase; plasmid, vector – all Higher only); Bacillus thuringiensis; biological control Character pillar links During this topic the following character pillar/s will be discussed: Curiosity, determination Home study tasks Task description Deadline PROJECT: Produce a research project on a genetic disease that provides protection against an infection: e.g. cholera and cystic fibrosis, or sickle-cell and malaria. Set by class teacher. Learn the spellings for each of the keywords and consider how you would use each word in a sentence. Set by class teacher. Revise for tests and exams. Progress assessments 7 and 8 How did genetics change the five kingdoms of life into three domains? Why do our crops and livestock produce so much food? What is genetic modification? How can bacteria produce insulin? (Higher) Can food production keep pace with human population growth?
