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All organisms -living things are made of cells. Cells do the jobs that keep organisms alive. Cells Cells are the smallest part of a living thing. These cells are like tiny building blocks. Discovery of Cells • The invention of the lens • Robert Hooke (1665): observed a thin slice of cork (dead plant cells) with a microscope. He described what he observed as “little boxes” (cells). Discovery of Cells • Antonie van Leeuwenhoek (1675) Dutch tradesman and scientist was the first person to observe living cells. Handcrafted microscope The Cell Theory • Who developed the cell theory? – Matthias Schleiden (1838): concluded that all plants are composed of cells – Theodor Schwann (1839): concluded that all animals are composed of cells – Rudolph Virchow (1855): determined that cells come only from other cells Cell Theory • All living things composed of cells • Cells are the basic unit of structure and function in living things • New cells are produced from existing cells Microscopes • Magnification: refers to the microscope’s power to increase an object’s apparent size • Resolution: refers to the microscope’s power to show detail clearly Observing Cells • Light microscope – Can observe living cells in true color – Magnification of up to ~1000x – Resolution ~ 0.2 microns – 0.5 microns Observing Cells • Electron Microscopes – Preparation needed kills the cells – Images are black and white – may be colorized – Magnification up to ~100,000 times 2D or 3D images Blood cells Cell Diversity- Size Smallest Cells: Bacterium 2-10 micro meters Biggest Cells: Ostrich egg 6 inches long, 5 inches wide, 3 pounds Longest Cells: Giraffe nerve cell is up to 2 m Cell Diversity- Shape • Cells differ widely in shape. • Most cells are roughly cuboidal or spherical. Cell Diversity- Internal Organization • Nucleus: contains DNA which directs the activity of the cell • Organelle: a cell component that performs specific functions in the cell • Eukaryotes: cells that contain a nucleus and membranebound organelles • Prokaryotes: cells that lack nuclei and membrane-bound organelles Why Are Cells So Small? • Cells need sufficient surface area to allow adequate transport of nutrients in and wastes out. • As cell volume increases, so does the need for the transporting of nutrients and wastes. Why Are Cells So Small? • However, as cell volume increases the surface area of the cell does not expand as quickly. – If the cell’s volume gets too large it cannot transport enough wastes out or nutrients in. • Thus, surface area limits cell volume/size. Why Are Cells So Small? • Strategies for increasing surface area, so cell can be larger: – “Frilly” edged……. – Long and narrow….. • Round cells will always be small. Cell: • Organisms that do not have a distinct nucleus— prokaryotic (PRO = NO) Ex: bacteria • Organisms with cells that have true nucleus and organelles—eukaryotic (EU = TRUE) Ex: plants, animals, fungi Nucleus—control center of the cell Double membrane that surrounds the nucleus— nuclear membrane • Hereditary information inside the nucleus— chromatin (DNA)