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Review Article VARIOUS BIOLOGICAL APPROACHES TO ACCELERATE 55TOOTH MOVEMENT DURING ORTHODONTIC TREATMENT: A 59 REVIEW Amit Kalra, Kartikeya Singh, Piyush Bolya, Anjali Yadav, Bhoopendra Singh Rajput, Rahul Puri Goswami DOI:10.4103/0972-124X.2170 Background:Duration of the orthodontic treatment has always been an issue in the orthodontic fraternity. Nowadays, there is an increased tendency for researches to focus on accelerating methods for tooth movement due to the huge demand for adults for a shorter orthodontic treatment time. Unfortunately, long orthodontic treatment time poses several disadvantages like higher predisposition to caries, gingival recession, and root resorption. This increases the demand to find the best method to increase tooth movement with the least possible disadvantages. The purpose of this study is to view the successful approaches in tooth movement and to highlight the newest technique in tooth movement. A total of 50 articles were reviewed in tooth movement and related discipline. In various researches done, cytokines PTH, Vit D, have shown good results. Due to the advantage and disadvantage of each approach further investigation should be done to determine the best method to accelerate tooth movement.