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J E u r o p European
a i s c h e sPatent Office
© Publication number:
Office europeen des brevets
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0
141
414
A2
PATENT A P P L I C A T I O N
© Application number: 84113286.3
© Int. CI.4: A 61
K 7/06
© Date of filing: 05.11.84
© Priority: 07.11.83 JP 208788/83
@ Date of publication of application:
15.05.85 Bulletin 85/20
@ Designated Contracting States:
DE FR GB IT
Hair tonic composition.
A hair tonic composition containing at least one plant
hormone selected from the group consisting of pchlorophenoxyacetic acid, sodium 5-chloro-tH-3indazolylacetate and a-naphthylacetamide as an effective
ingredient in a quantity of from 0.05 % to 3.0 % by weight.
© Applicant: KAKUDAI SHOSAN KABUSHIKI KAISHA
1-4, Kita-Machi
Kawagoe-Shi Saitama-Ken(JP)
@ Inventor: Someya, Kiyoshi
1-4, Kita-Machi
Kawagoe-Shi Saitama-Ken(JP)
@ Representative: Patentanwalte Dipl.-lng. Klaus Behn
Dipl.-Phys. Robert Munzhuber
Widenmayerstrasse 6/IV
D-8000Munchen22(DE)
BACKGROUND
This
invention
composition
adding
more
which
is
addition
the
is
are
and
grime
on
the
prevent
is
hair
the
and
are
circulation
at
the
function,
hair
itch,
hair
and
whereby
hair
the
loss;
removed
are
whereby
promoted;
the
afford
prevent
and
scalp
and
to
skin
to
in
to
sprouting
a refreshing
feeling
imparted.
hair
While
the
loss,
hair
apparent
for
activated
dandruff
growth
the
pre-
water
color
by
intended
is
blood
enhance
to
roots
the
tonic
and
perfume,
composition
effects:
improved
ethanol
as
glycol,
tonic
hair
dust
and
hair
following
scalp
such
tonic
prepared
hair
for
tonic
a hair
product
ingredients
propylene
The
like.
the
to
care
hair
to
to
particularly
solvents
to
INVENTION
generally
a hair
of
a variety
parations
relates
and
compositions
OF THE
hair
1)
in
tonic
the
respects,
many
and
hormone
2)
Vitamins
3)
Amino
acids;
4)
Crude
during
follicular
as
the
such
growth
been
to
with regard
following
have
preparations
such
hair
and
sprouting
Hormones
cortical
mechanism
physiological
is
not
ingredients
heretofore
hormone,
used:
adrenal
like;
vitamins
as
E,
B2
and
B6
and
the
like;
and
extract
5)
nate,
of
and
as
salicylic
acid
Scalp-stimulating
cantharis
Japanese
the
diphenhydramine
chirata
of
and
Germicides
alkyldiaminoethyl
agents
copricum,
the
and
hydro-
like;
Keratin-solubilizing agents
tincture
8)
such
glycyrrhizin
resorcinol,
7)
as
like;
Antiphlogistics
chloride,
6)
the
such
extracts
the
such
lactic
as
benzyl
vanilamide,
nicotitincture
like;
such
glycine
as
isopropyl
acid,
like;
such
nonylic
as
methylphenol,
hydrochloride
solution,
p-chloro-m-xylenol,
ammonium
quaternary
salts
and
the
like;
the
like;
9)
such
Refrigerants
such
Humectants
10)
sorbitol,.sodium
menthol
as
as
and
glycerin,
propylene
glycol,
and
dl-pyrrolidonecarboxylate
and
the
like.
because
However,
certain
as
tonic
to
the
hair
and
made
have
drawbacks
of
such
extensive
loss
hair
for
well
as
with
in
as
order
to
overcome
hair
art
prior
hair
effects.
promoting
such
accurate-
satisfactory
studies
accompanying
be
composition
entirely
growth -
is
ingredients
ingredients
hair
of
prevention
sprouting I
not
are
preparations
respect
certain
such
agents
it
safety,
amount
tonic
of
preparations
to
regard
hair
Further,
adjusted.
amount
large
scalp-stimulating
the
the
into
incorporated
with
a
tonic
and
that
required
of
use
half
germicides
drawbacks
cause
strictly
ly
for
ingredients
hormones,
may
the
tonic
compositions.
SUMMARY OF THE
It
a hair
is
tonic
various
ing
and
hair
invention
the
such
invention
present
which
composition
advantages
is
the
as
safe
and
provide
which
has
hair
of
promotion
to
sprout-
growth.
tonic
A hair
of
object
an
INVENTION
composition
at
comprises
least
selected
phytohormone,
from
and
the
present
hormone,
plant
or
of
consisting
group
5-chloro-1H-3-
sodium
acid,
p-chlorophenoxyacetic
indazolylacetate
one
the
to
according
a-naphthylacetamide
an
effective
been
hereto-
as
ingredient.
First,
fore
used
as
a
the
increase
growth
plant
of
bearing
low
temperatures,
shorten
the
maturation
phenoxyacetic
to
secure
the
acid
yield
has
of
regulator
fruits
order
known
in
as
the
to
and
fruit
Particularly,
period.
been
the
fatten
to
in
eggplants
tomatoes,
at
like
has
acid
p-chlorophenoxyacetic
and
of
to
p-chloro-
a compound
case
the
serving
forced
semi-forced
culture
or
quality
thereof.
hair
be
and
by
tonic
hair
using
as
root
sprouting
a
plant
that
hair
in
amide
a hair
and
and
hair
by
sodium
sprouting
cuttings
of
flowering
Japanese
hollys,
and
itch
promoting
a
plant
such
trees
known
growth -
promot-
a-naphthylacet-
growth
regulator
activation
or
of
as
Chinensis
Juniperus
cedars.
Himalayan
that
well
as
not
Enkianthus
osmanthus,
all
as
5-chloro-1H-3-indazolylacetate
root
at
such
composition.
promote
known
such
azaleas,
was
using
to
and
it
However,
as
trees
trees
pines;
saplings
such
laurels,
order
camellias
a
promote
(or
Japanese
obtained
tonic
to
garden
as
sweet
in
heretofore
order
plants
used
in
that
could
acid
been
cuttings
heretofore
has
effects
geraniums;
trees.
be
Furthermore,
been
of
sprouting -
could
effects
and
camellias,
sun
in
petal
daphnes,
and
cryptomeria
of
roses
trees,
spindle
has
regulator
cutting)
rhododendrons,
ing
all
at
p-chlorophenoxyacetic
activation
or
the
from
all
known
growth-promoting
growth
chrysanthemums,
at
the
improve
not
was
a-naphthylacetamide
used
as
to
composition.
Further,
grown
hair
and
it
However,
sprouting
obtained
culture
the
as
effects
of
prevention
hair
hair
be
obtained
in
5-chloro-1H-3-indazolylacetate
by
hair
dandruff
growth sodium
using
hair
a
not
was
loss,
and
sprouting -
could
it
However,
tonic
composi-
tion.
DESCRIPTION
DETAILED
When
in
alone
the
in
the
hair
to
5%
by
weight.
described
the
hair
present
tonic
when
tonic
is
each
invention,
at
from
preferably
Further,
5-chlorois
a-naphthylacetamide
composition
weight,
above
or
sodium
acid,
p-chlorophenoxyacetic
111-3-indazolylacetate
INVENTION
OF THE
a mixture
used,
composition
the
compound
level
a
0.05
of
in
a total
% to
the
compounds
of
used
is
present
from
0.001
3.0 %
by
compounds
are
present
amount
of
in
from
%
0.001
% to
3.0 %
by
5 % by
weight,
to
and
tonic
hair
invention
used
contain
can
hair
in
optional
tonic
various
water
and
tants
such
ethanol;
as
keratin-solubilizing
and
resorcinol
oxyethylene
ether;
vegetable
higher
alcohols
vitamins
If
such
and
chloride;
nicotinate
as
effects
can
be
selected
acid,
phenoxyacetic
enzymes
such
Furthermore,
of
activity
is
of
can
the
sodium
present
by
invention.
hair
tonic
growth least
at
combination
ficin,
one
of
the
and
plant
p-chloro-
by
acid,
incorporating
hair
tonic
pepsin.
of
reduction
or
a
the
5-chloro-
sodium
a-naphthylacetamide
the
promot-
with-proteolytic
bromelin
that
thought
in
hair
benzyl
5-chloro-1H-3-indazolylacetate
in
prevented
chloride
as
consisting
group
p-chlorophenoxyacetic
be
hydro-
invention.
sodium
it
such
the
hormone;
hydrochloride;
glycine
agents
in
tonic
follicular
as
using
1H-3-indazolylacetate,
thereof
such
enhanced
papain,
sodium
hair
and
as
alcohol;
octene;
as
diphenhydramine
a-naphthylacetamide
oil;
for
sprouting from
castor
ingredients
present
hair
Further,
lauryl
oleyl
and
such
poly-
preservatives.
incorporated
the
of
as
and
and
alkyldiaminoethyl
be
acid,
and
scalp-stimulating
can
composition
as
sorbitol;
agents;
hormones
as
such
such
salts
E;
other
oil
paraffin
coloring
necessary,
germicides
and
vitamin
and
such
alcohol
cetyl
liquid
perfumes;
antiphlogistics
hormone
as
as
preparations
ing
as
olive
as
humec-
menthol;
lactic
ethers
such
purified
polyoxyethylene
such
such
such
such
chloride;
oils
of
as
as
as
acid;
and
conventionally
glycerin
such
agents
ether
oleyl
hydrocarbons
glycol,
salicyclic
such
such
refrigerants
propylene
present
Examples
solvents
are
the
to
ingredients
compositions.
ingredients
a-naphthylacetamide,
according
composition
sodium
acid,
p-chlorophenoxyacetic
5-chloro-1H-3-indazolylacetate
the
% to
weight.
addition
In
0.05
from
preferably
mixtures
small
composition
amount
of
the
The
invention
tional
tonic
hair
be
can
acetic
that
the
from
is
following
but
thereof.
Throughout
these
expressed
in
are
not
"parts"
was
ingredients
When
onto
the
over
the
by
scalps
of
observed
that
and
front
the
gradually
ingredients
hormone
p-chlorophenoxy-
the
limit
to
and
present
the
scope
quantities
containing
the
in
and
downy
head
itch
hair
after
about
with
tinged
composition
prepared.
the
were
began
was
with
subjects
massaged
became
tonic
was
tonic
1
EXAMPLE
A hair
hair
therein.
composition
Japanese
dandruff
was
hair
tonic
well
were
of
conven-
following
prepared.
hair
3 months,
the
weight.
composition
this
scalps
of
examples,
EXAMPLE
tonic
with
plant
illustrate
intended
invention
A hair
one
incorporated
examples
are
present
5-chloro-1H-3-indazolylacetate
a-naphthylacetamide
The
the
ordinary
consisting
group
sodium
acid,
an
least
at
to
according
accordance
preparing
except
composition
in
prepared
for
process
selected
composition
to
applied
thin
morning
hair
and
prevented,
sprout
3 weeks.
daily
on
This
and
evening
and
the
it
back
downy
black.
2
containing
the
following
this
When
the
onto
the
were
3 months,
the
that
and
the
new
back
tonic
ingredients
of
and
the
the
evening
scalps
of
and
in
it
the
over
was
to
after
evening
and
prevented,
began
head
and
and
in
sprout
about
3 weeks.
3
the
containing
following
prepared.
hair
tonic
well
3 months,
observed
vicinity
of
composition
Japanese
were
scalps
were
daily
hair
thin
morning
hair
the
applied
with
the
itch
composition
this
When
onto
was
in
downy
EXAMPLE
A hair
was
subjects
massaged
dandruff
of
vicinity
composition
Japanese
well
observed
was
tonic
scalps of
scalps
over
it
hair
dandruff
that
the
new
back
with
subjects
massaged
downy
of
in
and
the
was
the
itch
applied
thin
hair
morning
were
daily
and
prevented,
hair
began
to
head
after
about
sprout
4
weeks.
EXAMPLE
A hair
ingredients
tonic
was
composition
prepared.
4
containing
the
following
this
hair
scalps
of
When
onto
and
the
the
over
and
it
the
back
This
well
3 months,
and
front
hair
downy
the
gradually
head
tonic
was
ingredients
onto
and
the
the
evening
scalps
of
and
in
3 w
it
over
was
the
were
tonic
observed
of
e
ingredients
e
tonic
was
prevented,
sprout
on
3 weeks.
with
the
containing
well
massaged
dandruff
that
the
new
back
black.
following
and
the
itch
thin
hair
morning
were
daily
and
prevented,
hair
began
to
the
head
after
about
of
composition
in
applied
downy
k
prepared.
was
with
subjects
EXAMPLE
A hair
to
about
composition
Japanese
3 months,
vicinity
and
prepared.
hair
scalps
were
began
tinged
hair
morning
itch
daily
5
composition
this
When
thin
the
after
became
EXAMPLE
A hair
in
hair
downy
applied
with
and
dandruff
of
was
subjects
massaged
that
observed
was
composition
Japanese
were
scalps
evening
tonic
s
sprout
.
6
containing
the
following
this
hair
scalps
of
When
onto
the
the
and
scalps
and
in
it
the
were
vicinity
dandruff
that
of
the
was
new
back
in
and
thin
the
the
daily
hair
and
morning
itch
downy
of
applied
with
subjects
well massaged
observed
was
composition
Japanese
3 months,
over
evening
tonic
were
prevented,
hair
began
to
head
after
about
sprout
4
weeks.
EXAMPLE
A hair
tonic
was
ingredients
onto
and
the
the
evening
scalps
of
over
it was
the
back
This
downy
tonic
well
3 months,
front
hair
composition
subjects
Japanese
were
observed
and
dandruff
that
of
the
gradually
ingredients
tonic
was
downy
head
and
hair
after
became
composition
prepared.
in
massaged
EXAMPLE
A hair
the
containing
following
prepared.
hair
scalps
and
composition
this
When
7
was
applied
with
the
thin
were
to
began
about
tinged
hair
morning
itch
daily
and
prevented,
sprout
on
3 weeks.
with
black.
8
containing
the
following
onto
the
the
and
in
it
scalps
well
dandruff
the
of
was
new
back
applied
with
subjects
and
daily
thin hair
the
in
massaged
that
observed
vicinity
composition
of Japanese
3 months,
over
was
the
tonic
were
scalps
evening
and
hair
this
When
and
morning
itch
were
prevented,
downy
hair
began
to
the
head
after
about
of
sprout
3
weeks.
EXAMPLE
A hair
tonic
was
ingredients
onto
and
the
the
scalps
of
over
and
in
it
the
was
were
3 weeks.
tonic
observed
of
composition
Japanese
well
3 months,
vicinity
the
containing
following
prepared.
hair
scalps
evening
composition
this
When
9
dandruff
that
the
new
back
with
subjects
massaged
in
and
was
the
itch
applied
thin
hair
morning
were
daily
and
prevented
downy
hair
began
to
the
head
after
about
of
sprout
one
tonic
A hair
1.
plant
group
hormone,
or
of
consisting
composition
and
an
effective
2.
The
wherein
said
from
the
sodium
acid,
p-chlorophenoxyacetic
5-chloro-lH-3-indazolylacetate
as
selected
phytohormone,
least
at
comprising
a-naphthylacetamide
ingredient.
hair
tonic
composition
hormone
plant
is
according
claim
to
1
p-chlorophenoxyacetic
acid.
3.
The
wherein
said
hair
tonic
composition
hormone
plant
according
sodium
is
to
claim
1
5-chloro-1H-3-
indazolylacetate.
4.
The
wherein
said
5.
The
wherein
said
in
a
The
wherein
said
a
which
hair
The
hair
additionally
bromelin
and
The
is
in
the
5%
% to
by
the
claim
1
weight.
claim
to
in
the
by
weight.
present
% to
3.0 %
composition
according
a proteolytic
consisting
of
1
composition
is
contains
group
present
to
according
0.05
tonic
claim
composition
hormone
from
to
a-naphthylacetamide.
according
0.001
tonic
of
from
which
from
is
according
composition
hormone
plant
selected
8.
tonic
of
hair
composition
hormone
plant
quantity
7.
tonic
plant
quantity
6.
in
hair
5
composition
to
claim
1
enzyme
papain,
ficin,
pepsin.
hair
additionally
tonic
composition
contains
sodium
according
chloride.
to
claim
1