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Patient information Exemestane (Aromasin) Breast Services Directorate PIF 1008 V3 What is Exemestane? Exemestane is a drug used to treat breast cancer in women who have gone through the menopause (change of life). Why am I being given Exemestane? Exemestane has been shown to be an effective treatment for people who have been told they have breast cancer. This tablet may be given to people who have received other breast cancer drugs. How does it work? Many breast cancers use the female hormone (oestrogen) to grow. You will only be given Exemestane if you have this hormone positive type of cancer. (This type of breast cancer is the most common sort.) After the menopause the ovaries stop working, but two substances come together in the body to make a small amount of oestrogen. Exemestane stops these substances coming together in the body to make oestrogen and this means there is less oestrogen going to the breast. What is the dose? Exemestane is taken as one 25mg tablet each day, preferably after a meal. Your hospital doctor will prescribe one months treatment and you will need to get a repeat prescription from your family doctor (GP). Remember, you will need to get a prescription for more tablets from your GP before your hospital supply runs out. What happens if I forget one day? Do not panic. After you have been taking Exemestane for a few days, the amount in your blood stream will get you by. You should take your next tablet at the same time as usual the next day. Please remember to pack enough tablets if you go away on holiday. What are the side effects? It must be remembered that most women take Exemestane with few if any, side effects. However, the following side effects are possible. More common side effects include: Hot flushes and sweats Hair loss Vomiting or feeling sick Fatigue / feeling tired Insomnia (difficulty sleeping) Anorexia (loss of appetite) Abdominal pain Skin rash Depression Constipation Dyspepsia (indigestion) Headache Less common side effects include: Swelling in the legs Dizziness If you have any of these side effects please discuss them with your doctor. Can I take Exemestane with other medicines? Exemestane can react with some medicines so please tell your doctor about the medicines you are taking. Can I drink alcohol while taking Exemestane? Yes. It is safe to drink alcohol. What will happen if I decide not to have this treatment - are there any alternatives? There may be an alternative to exemestane, this and the affects of not having treatment can be discussed with your consultant or Breast Care Nurse if you wish. Further Information If you any further questions, or would like to talk through any of the above in more detail, please contact your Breast Care Nurse. You could see your GP or Hospital Consultant. The Breast Care Nurses: Tel: 0151 706 2927 (24 hour answerphone) Textphone Number: 18001 0151 706 2927 Breast Nurse Practitioner Tel: 151 706 2931 Textphone Number: 18001 0151 706 2931 Or you may like to contact: Breast Cancer Care Tel: 0808 8006000 Website: www.breastcancercare.org.uk Macmillan Tel: 0808 808 00 00 There are many local support groups, please ask your Macmillan Breast Care Nurse. Author: Breast Service Directorate Review date: April 2017 All Trust approved information is available on request in alternative formats, including other languages, easy read, large print, audio, Braille, moon and electronically.