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Stimulants What are Stimulants? Central nervous system stimulants speed up activity of the nervous and muscular systems. Heart rate accelerates, blood pressure rises, blood vessels constrict, and the pupils of the eyes and the bronchial tubes dilate. They are generally used for their ability to increase alertness and endurance, to keep users awake for a long period of time, to decrease appetite, and to produce feelings of well-being and euphoria. Cocaine Cocaine is a potent central nervous system stimulant derived from the leaves of cocoa shrubs from South America. Introduction of “crack” cocaine in the 1980’s made cocaine available in smaller quantities and at lower prices to more people. Cocaine - ways of ingestion Cocaine is usually inhaled or injected intravenously. Effects of intravenous injections occur in about 20 seconds. Intravenous creates rapid increases of cocaine in the blood and therefore fast and intense effects. “Crack” cocaine involves processing the drug with baking soda and water yielding the powder form of cocaine that is smoked. The term “crack” refers to the crackling sound heard when the mixture is smoked. Because crack is smoked, the user experiences a high in less than 10 seconds. What are the effects of cocaine? Cocaine’s effects appear almost immediately after a single dose, and disappear within a few minutes or hours. Taken in small amounts cocaine usually makes the user feel euphoric, energetic, talkative, and mentally alert, especially to the sensations of sight, sound and touch. It can also temporarily decrease the need for food and sleep. Some short-term physiological effects of cocaine include constricted blood vessels; dilated pupils; and increased temperature, heart rate, and blood pressure. Large amounts intensify the user’s high, but may also lead to bizarre, erratic, and violent behavior. These users may experience tremors, and muscle twitches. Some users of cocaine report feeling of restlessness, irritability, and anxiety. In rare instances, sudden death can occur on the first use of cocaine or unexpectedly thereafter. Cocaine is a powerfully addictive drug. An appreciable tolerance to cocaine’s high may develop, with many addicts reporting that they seek but fail to achieve as much pleasure as they did from their first experience. Some users will frequently increase their doses to intensify and prolong the euphoric effects. In addition, research has revealed a potentially dangerous interaction between cocaine and alcohol. While more research needs to be done, it is noteworthy that the mixture of cocaine and alcohol is the most common two-drug combination that results in drug-related death. Methamphetamine Methamphetamine is commonly known as “speed,” “meth,” and “chalk.” In its smoked form it is often referred to as “ice,” “crystal,” “crank,” and “glass.” It is a white, odorless, bitter-tasting crystalline powder that easily dissolves in water or alcohol. The drug is made easily in clandestine laboratories with relatively inexpensive over-the-counter ingredients. These factors combine to make methamphetamine a drug with high potential for widespread abuse. Methamphetamine – ways of ingestion Methamphetamine comes in many forms and can be smoked, snorted, orally ingested, or injected. The drug alters moods in different ways, depending on how it is taken. Immediately after smoking the drug or injecting it intravenously, the user experiences an intense rush or “flash” that lasts only a few minutes. Snorting or oral ingestion produces euphoria- a high but not an intense rush. In the 1980’s, “ice,” a smokable form of methamphetamine, came into use. Ice is a large, usually clear crystal of high purity that is smoked in a glass pipe like crack cocaine. The smoke is odorless, leaves a residue that can be resmoked, and produces effects that may continue for 12 hours or more. What are the effects of methamphetamine? As a powerful stimulant, methamphetamine, even in small doses, can increase wakefulness and physical activity and decrease appetite. A brief, intense sensation, or rush, is reported by those who smoke or inject methamphetamine. Oral ingestion or snorting produces a long-lasting high instead of a rush, which reportedly can continue for as long as half a day. High doses can elevate body temperature to dangerous, sometimes lethal, levels, as well as cause convulsions. Long-term methamphetamine abusers exhibit symptoms that can include violent behavior, anxiety, confusion, and insomnia. They also can display a number of psychotic features, including paranoia, auditory hallucinations, mood disturbances, and delusions (for example, the sensation of insects creeping on the skin, called “formication”). The paranoia can result in homicidal as well as suicidal thoughts. With chronic use, tolerance for methamphetamine can develop. In an effort to intensify the desired effects, users may take higher doses of the drug, take it more frequently, or change their method of drug intake. Chronic abuse can lead to psychotic behavior, characterized by intense paranoia, visual and auditory hallucinations, and out-of-control rages that can be coupled with extremely violent behavior. Other Abused Stimulants Ephredrine Ephedrine can be purchased over-the-counter in various weight loss pills. It is somewhat less potent than amphetamines. Used for centuries as a stimulant often under it’s traditional Chinese name, Ma huang. It is very common for ephedrine to be abused and taken in larger amounts than advised. Ephedrine triggers a mild burst of energy, due to its similarities to the body hormone epinephrine (or adrenaline) and the street drug methamphetamine. When abused ephedrine can cause abnormality in heart rhythm and raise heart beat to dangerously high levels. It has even been known to cause death. Two very common products with ephedrine in it are Ripped Fuel and Xenedrine. Fill In the Blank Questions Central nervous system stimulants speed up activity of the _____________ and _______________ systems. Cocaine is a potent central nervous system _________________ derived from the leaves of _____________________ from South America. Cocaine is usually ___________________ or injected intravenously. “Crack” cocaine involves processing the drug with _______________________ water yielding the powder form of cocaine that is smoked. Cocaine’s effects appear almost __________________________ after a single dose, and disappear within a few minutes or hours. In rare instances, _____________ ________________ can occur on the first use of cocaine or unexpectedly thereafter. ______________________________ is a white, odorless, bitter-tasting crystalline powder that easily dissolves in water or alcohol. High doses of methamphetamine can elevate ______________ ___________________ to dangerous, sometimes lethal, levels, as well as cause convulsions. _______________________ can be purchased over-the-counter in various weight loss pills. Ephedrine has been used for centuries as a stimulant often under it’s traditional Chinese name, _______ ______________. True/False Questions (Circle correct answer) When under the influence of a stimulant the heart rate accelerates, blood pressure rises, blood vessels constrict, and the pupils of the eyes and the bronchial tubes dilate. TRUE FALSE Effects of intravenous injections occur in about 20 minutes. TRUE FALSE The effects of cocaine and alcohol offset each other and can reduce the negative effects of both. TRUE FALSE Methamphetamine is commonly known as “speed”, “meth,” and “chalk.” In its smoked form it is often referred to as “ice,” “crystal,” “crank,” and “glass.” TRUE FALSE As a powerful stimulant, methamphetamine, even in small doses, can increase wakefulness and physical activity and increase appetite. TRUE FALSE Oral ingestion or snorting of methamphetamine produces a long lasting high instead of a rush, which reportedly can continue for as long as half a day. TRUE FALSE With chronic use, tolerance for methamphetamine can develop. FALSE TRUE