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Biology 321 QUIZ#1 Winter 2011 Total points: 25 NAME________________________ 1. (3 pts.) Genetic factors are thought to cause more than 50% of all cases of congenital hearing loss (child is born deaf) in humans. Even though hundreds of genes are required for the development and functioning of the inner ear, hereditary deafness is a single gene trait. In one or two nicely crafted sentences explain the apparent contradiction in the second statement. Student Answers: Even though many genes are required for ear development and function, the mutation of just one gene (component of development) can disrupt function. This is why hearing is considered a single gene trait. If there is a mutation in any one of the genes contributing to the development and functioning of the inner ear, hereditary deafness will occur. If many genes are necessary for inner ear development, then a defect in just one could easily make it impossible for the ear to develop normally, if it controls a crucial protein. NOTE: A single gene trait means that allelic variation in one of these genes can cause deafness. It in no way implies that mutations in only one of the gene involved in the development and functioning of the ear can cause deafness. Indeed mutations in many of these genes can result in deafness 2. (2 pts.) Circle T or F for each statement. Answer false any part of the statement is false. If there are two statements, the first statement is true and you are to decide if the second statement is T or F. FALSE Commercially valuable strains of strawberries can be 2n=14, 4n=28, 6n=42 or 8n=56. This information implies that these strains differ with respect to the number of different chromosomes (double stranded DNA molecules per single genome copy. TRUE The genome of the domestic dog (Canis familiaris) is summarized as 2n= 78. Each product of meiosis I in the dog gonad would contain 39 chromosomes and 78 ds(doublestranded) DNA molecules and each product of meiosis II would contain 39 chromosomes and 39 ds DNA molecules. 3. (4pts. total) You self an F1 plant of genotype AaBbCc and select one F2 plant at random. Assume all three genes are on different chromosomes. Show your work and circle your answer. AaBbCc X AaBbCc a. (2 pts.) What is the probability that this plant will be true-breeding for all three dominant phenotypes? Truebreeding dominant = AABBCC = ¼ X ¼ X ¼ = 1/64 b. (1 pt.) What is the probability that a given F2 plant will be truebreeding for either the dominant or recessive phenotype conferred by gene A? either AA or aa = ¼ + ¼ = ½ c. (1 pt.) What is the probability that a given F2 plant will be truebreeding for all three genes? extending calculation in b ½ X ½ X ½ = 1/8 hard way: figure out all possible genotypes and add their individual probabilities together: AABBCC + aabbcc + AAbbCC etc. (8 different possibilities 1 4. (12 pts) You are exploring the inheritance of two traits in jimsonweed plants. The purple smooth parent is from a true-breeding laboratory stock. The other parental plants were taken directly from a field near Mt Baker. Different white parental plants were used in each cross Trait Flower color Pod morphology Alternative phenotypes Purple or White Spiny or Smooth Progeny phenotypes: number in each class C R O S S Parental phenotypes White Spiny Purple Smooth White Smooth Purple Spiny 1 White Smooth X 300 cW pSP pSM 100 300 100 c c pSM pSM c – pSM pSM cP cP pSP pSM 200 cW cP pSP pSM 200 200 200 W P c c p SM p SM White Spiny P P W cW cP pSP pSM 2 White Spiny X W c c P SP p p SM Purple Smooth cP cP P P c c pSM pSM W P c c pSM pSM cP cP pSP pSM pSM pSM a. Which trait flower color trait is dominant? WHITE For part b, fill in the blank from the choices below. No explanation needed. b. BOTH CROSSES (were) informative for determining dominance of this trait. Cross 1 only Cross 2 only Both crosses c. Which trait pod trait is dominant ? SPINY For part d, fill in the blank from the choices below. No explanation needed. d. CROSS 2 ONLY was (were) informative for determining dominance of this trait. Cross 1 only Cross 2 only Both crosses e. For each cross indicate the genotypes of the parents and progeny in the space underneath the phenotype. Use these allele designations OR define your own alleles symbols below. cP= purple cW = white pSP = spiny pod pSM = smooth pod OPTIONAL: Use your own alleles symbols. Define them here: 2 5. (4 pts.) Examine the anaphase diagrams shown below which were taken from one your assigned problems in Chapter 3. Each line represents a molecule of double-stranded DNA. (Chromosomes will segregate as indicated.) The dotted line indicates where the cytoplasm will be divided in cytokinesis. [HINT: If you are having trouble with these questions, think about what the chromosome content would look like in metaphase.] a. The diagram shown below is consistent with which of the scenarios listed below? Choose all correct interpretations. Do not circle an option if any part of it is incorrect. a. A 2n=4 cell undergoing mitosis b. Meiosis I in a 2n=4 organism of genotype AaBb or AaBB c. Meiosis I in a 2n=4 organism of genotype aaBB d. Meiosis I in a 2n=2 organism of genotype aaBB e. Meiosis II in a 2n=4 organism of genotype aaBB f. Meiosis I in a 4n=4 organism All B chromosomes consist of two dsDNA molecules b. The diagram shown below is consistent with which of the scenarios listed below? Choose all correct interpretations. Do not circle an option if any part of it is incorrect a. Mitosis in a 2n=4 cell of genotype AaBb b. Mitosis in a 2n=8 cell of genotype AaBb c. Mitosis in a 4n=4 cell d. Meiosis I in a 2n=4 organism of genotype AaBb e. Meiosis II in a 2n=8 organism f. Meiosis II in a 4n=8 organism of genotype AAaaBBbb 3 Question Score (pts.) 1-3 ( 9 ) 4 ( 12 ) 5 ( 4) Total 25 pts 4