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Treatment of Advanced Cervical Cancer and Palliative Care of Patients Dr. Martha Jacob PATH Video transcript is located below each slide. Treatment of Advanced Cervical Cancer and Palliative Care of Patients—1 How cervical cancer develops -------------------------------- 15–20 years -------------------------------- Source: Wright TC and Schiffman M. Adding a Test for Human Papillomavirus DNA to Cervical-Cancer Screening. The New England Journal of Medicine. 2003;348:489–490. Transcript: There’s compelling evidence to date that human papillomavirus infection is a necessary cause for cervical cancer. The majority of the women who get infected with human papillomavirus infection clear the infection spontaneously. But for a small group of women, this infection persists, and then progresses to precancerous lesions, which, if left untreated, can go on to develop cervical cancer. Treatment of Advanced Cervical Cancer and Palliative Care of Patients—2 Invasive cancer: common where there is no screening Cancer symptoms only become evident late in the course of disease. Cancer treatment greatly improves survival rates, except for the most advanced stages of disease. Stage of the cancer determines treatment—typically surgery or radiation, with or without chemotherapy. Invasive cancer is a common outcome when there is no screening. Cancer symptoms include vaginal discharge, bleeding, and pain. However, these symptoms become apparent and evident only later in the course of the disease. When available, cancer treatment greatly improves survival rates, except where the disease is diagnosed in the most advanced cases. The stage of the patient’s cancer determines the treatment options. Typically, it is through surgery or radiotherapy, with or without chemotherapy. Treatment of Advanced Cervical Cancer and Palliative Care of Patients—3 Improving treatment outcomes Providers must be trained to recognize symptoms and signs. Treatment is often available only in central facilities. Radiotherapy is key to successful treatment. Providers must coordinate with caregivers at home. Patients need access to treatment over the long-term. Health care providers need training to recognize these symptoms and signs, and treatment for invasive cancer requires specialized skills often available only in tertiary facilities. Basic radiotherapy capabilities are key to successful treatment. Providers in tertiary hospitals must coordinate with follow-up caregivers in the patient’s community, including members of the family. Patients need ongoing access to treatment over the long term. Treatment of Advanced Cervical Cancer and Palliative Care of Patients—4 Palliative care and pain management Palliative care seeks to avoid unnecessary suffering during the final stages of disease. Pain control is a human right, but is often neglected. Pain can be controlled with a combination of medical and non-medical interventions. Patients and caregivers need training for effective palliative care, including end-oflife counseling. Palliative care and pain management is part of the treatment for cancers, including cervical cancers. The goal of palliative care is to avoid unnecessary suffering during the final stages of the disease. Pain control is a vital component of palliative care and is also a basic human right. Yet, it is often neglected in cancer control programs. Pain can be effectively controlled, using a combination of medical and non-medical interventions. Patients and caregivers need training for effective palliative care, including end-of-life counseling. Treatment of Advanced Cervical Cancer and Palliative Care of Patients—5