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Table 2. Dosing of Selected Enteral Contrast Agents According to Product Labeling Drug Dosage How Concentration Comments Supplied Oral Rectal Barium E-Z-Disk 3,27 Swallow one 700 mg Not labeled Tablet 700 mg Tablet is ½ inch in tablet with 1-2 diameter and will swallows of water disintegrate within 30 minutes. E-Z-HD 28 Adults Not labeled Suspension 98% w/w Use immediately after 65 mL to 135 mL reconstitution. Digibar 190 29 Adults Not labeled Powder for 190% w/v Use within 8 hours of 120 mL suspension reconstitution. Maxibar 30 Adults Not labeled Suspension 210% w/v Use undiluted for 50 mL to 120 mL double-contrast examination of the esophagus, stomach and duodenum. Not labeled Suspension 60% w/v Use undiluted for single Liquid E-ZAdults contrast fill stomach Paque 31 Single contrast fill with small bowel followstomach with small through, routine small bowel follow through: bowel, and follow 150 mL to 340 mL through small bowel after double contrast Routine small bowel: upper GI study. 340 mL to 750 mL Ultra-R 32 E-Z-Paque 33 Follow through small bowel after double contrast upper GI study: 340 mL to 750 mL Adults Upper GI: 150 mL to 340 mL Small bowel: 340 mL to 750 mL Adults Upper GI: 150 mL to 340 mL Small bowel: 340 mL to 750 mL Not labeled Powder for suspension 95% w/w After reconstitution, use within 48 hours and refrigerate. Used when rapid transit through bowel is required. Not labeled Powder for suspension 96% w/w After reconstitution, use within 48 hours and refrigerate. Table 2 continued. Dosing of Selected Enteral Contrast Agents According to Product Labeling Drug Dosage How Concentration Comments Supplied Oral Rectal Barium Adults Suspension 105% w/v Volume and Liquid Polibar Adults 100% w/v concentration used Plus Double-contrast Single depends on esophagus study: 60 contrast gastrointestinal location Liquid Polibar mL to 300 mL studies: 1000 34,35 being imaged, undiluted suspension. mL to 2500 technique and mL of diluted equipment. Single or double suspension. contrast stomach Dilute in 1:5 series: 150 mL to 340 ratio. mL diluted or undiluted, depending Double on study. contrast colon studies: 500 Small bowel series: mL to 1500 340 mL to 750 mL mL of undiluted suspension. Adults Readi-CAT 2 36 Adults Suspension 2.1% w/v Shake well prior to use. 30 minute barium 300 mL to 400 Readi-CAT 2 is administration mL rectally. available in the protocol for following flavors: apple, abdomen: Give 300 banana, vanilla, berry, mL 30 minutes before and mochaccino. CT scan and 150 mL immediately prior to scan. 90 minute barium administration protocol for abdomen: Give 450 mL 90 minutes before CT scan, give another 300 mL 30 minutes before scan, and 150 mL immediately prior to scan. Table 2 continued. Dosing of Selected Enteral Contrast Agents According to Product Labeling Drug Dosage How Concentration Comments Supplied Oral Rectal Barium Not labeled Powder for 2% w/w After reconstitution, use E-Z-CAT Dry 37 Adults suspension within 48 hours and 30 minute barium refrigerate. administration protocol for abdomen: Give 300 mL 30 minutes before CT scan and 150 mL immediately prior to scan. 90 minute barium administration protocol for abdomen: Give 450 mL 90 minutes before CT scan, given another 300 mL 30 minutes before scan, and 150 mL immediately prior to scan. VoLumen® 38 Adults 900 to 1350 mL orally given 20 to 30 minutes prior to procedure. Water soluble iodinated contrast media Diatrizoate Adults meglumine and 30 to 90 mL diatrizoate sodium Pediatric Patients (Gastrografin®)9 Infant to children < 5 years: 30 mL Children 5 to 10 years: 60 mL For CT use: Adults 240 mL of diluted solution 15 to 30 minutes prior to procedure. To make a dilute solution mix 25 mL Gastrografin with one liter tap water. Not labeled Suspension 0.1% w/v Dose can be increased to 1800 mL for enhanced marking, in patients with delayed transit time and for obese patients. Adults 240 mL in 1000 mL tap water. Solution 37% organically bound iodine For pediatric patients weighing 10 kg or less and debilitated children, dilute 1 part Gastrografin in 3 parts water. Pediatric patients < 5 years of age: 1:5 dilution in tap water >5 years of age: 90 mL in 500 mL tap water. Table 2 continued. Dosing of Selected Enteral Contrast Agents According to Product Labeling Drug Dosage How Concentration Comments Supplied Oral Rectal Nonionic iodine based contrast agents Can be given Solution 30.2% to Give the oral dose 20 to Iohexol Adults 75.5% 40 minutes prior to (Omnipaque®)10 Undiluted Omnipaque rectally with larger volumes intravenous dose. 350: 50 to 100 mL used. The product For pediatric patients, Diluted Omnipaque labeling does the total iodine dose Concentration: should not exceed 5 not provide 6 to 9 mg Iodine/mL: gram iodine for patients specific 500 mL to 1000 mL under 3 years of age dosages. Note: smaller and 10 grams iodine for volumes are needed patients 3 to 18 years as concentration is of age. increased. Pediatric Patients Undiluted Omnipaque < 3 months of age: 5 to 30 mL 3 months to 3 years: up to 60 mL 4 to 10 years: up to 80 mL > 10 years: up to 100 mL Diluted Omnipaque Concentration: 9 to 21 mg Iodine/mL: 180 mL to 750 mL Note: smaller volumes are needed as concentration is increased. Iohexol can be mixed with water, juice, milk or carbonated beverage. 10,39 Omnipaque 350 is labeled for pass thru examination in adults. Omnipaque 300 and Omnipaque 240 are labeled for pass thru examination in children