Download Mitosis pop beads lab

Mitosis Simulation Lab
Purpose: to observe the propefties of a cell and a chromosome as it changes
during mitosis.
Materials
20 red pop beads (each bead represents one gene)
20 yellow pop beads
4 magnetic centrosomes
4 hollow tubes (centrioles)
String
2 Plastic bags
Red and yellow colored pencils (any two colors will do)
Procedure:
Take everything out of the plastic bag and check the inventory. Take 10 red pop
beads and put 5 on each end of a centrosome. Do the same with the yellow
beads. This represents 2 chromosomes (2n-2) of a simple organism. The red
beads came from one parent and the yellow chromosomes came from the other
parent. Be sure to LABEL each drawing. Label all the pafts of the cell you have
drawn, at least one time.
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G-1 Put the 2 chromosomes (red and yellow) back into the plastic bag and set it
on the table. Put two centrioles together 4 inches from the plastic bag. The
plastic bag represents the nuclear membrane around the chromosomes. Draw
this using two colored pencils and draw the genes in each. (Draw a cell
membrane around the nucleus and the centrioles)
the remaining 10 red pop beads and put 5 on each end of the remaining
centrosome. Do the same with the yellow. Put these into the plastic bag on the
table. What has happened to the chromosome number? The 2 two red
chromosomes are called sister chromatids. Leave the centrioles where they are
on the desk. Draw this.
S Take
G-2 Take the two remaining centrioles and put them about 3 inches away from
the first two centrioles and toward the nucleus. Put the string between the 2 sets
of centrioles. Draw this model now.
Mitosis
Prophase Remove the chromosomes from the plastic bag. Wrap them around
each other and replace them on the table where the plastic bag was. Move the
centrioles to either side of the chromosomes. Extend a string from the centrioles
across the chromosomes to the other centriole. The string represents the spindle
fibers. Draw the completed step.
Metaphase. Align two red chromosomes and two yellow chromosomes above or
below each other on the table. The end of the red strand is just above the yellow
strand. Drape string over the centromere of the yellow and over the red
centromeres. The end of the string should still be in contact to the centrioles at
the ends or poles of the diagram. Draw this step
Anaphase Grasp the centrosomes on the red chromosomes and put them apaft
toward each opposite centrioles. Note as you pull it the lagging ends of the
chromosomes are toward the equator or center of you model and the
centrosome is more toward the centriole. Do the same with the yellow. Draw this
model and make sure the chromosomes with their genes make the characteristic
V shape found in anaphase.
Telophase. Take the chromosomes and put them two separate plastic bags.
This represents the reformation of the nuclear envelope. Next the each plastic
bag should be one pair of centrioles. Draw this model with one circle surrounding
both nuclei and all the centrioles.
Cytokinesis Draw a furrow in between the two nuclei to indicate the cell
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membrane is being pinched to form two cells. Each cell should have one nucleus
with a yellow and red chromosome and a pair of centrioles. It should look the
same as the G-1 cell. In a human cell, the cytokinesis cells will be smaller than
the G-1 cell.
Put the all the beads, centrioles, centromeres, and other plastic bag into one
plastic bag. Return this to the to the instructor. Be sure to name each stage of
the process.
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