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1 Heroin Addiction: Prevention, Treatment and Recovery Robert Lubran Director, Division of Pharmacological Therapies Center for Substance Abuse Treatment Substance Abuse and Mental Health Services Administration Maryland Community Action Partnership 1 May 12, 2015 2 Trends in Heroin Use in the United States: 2002 to 2013 Majority of heroin flowing to U.S. markets is from South America and Mexico 3 3 Domestic Heroin Seizures: United States, 1999–2013 4 Kilograms Seized 6,000 5,000 4,000 3,000 2,000 1,000 NOTE: Includes deconflicted seizures by all Federal agencies and 0 some state local 2001 2002 2003and 2004 2005agencies. 2006 2007 2008 2009 2010 2011 2012 2013 4 2/2015 Source: El Paso Intelligence Center. National Seizure System. Unpublished data extracted by ONDCP. Data for 2001 to 2007 were extracted on December 1, 2012 and data for 2009 to 2013 were extracted on April 17, 2014. + 181% Change from 2006 to 2013 Drug poisoning death rates involving heroin United States 5 Deaths per 100,000 population 8 2000 7 2013 6 5 4 3 2 1 0 Age 18-44 Age 45-64 Age 18-44 Age 45-64 Age 18-44 White, non-Hispanic Black, non-Hispanic SOURCE: CDC/NCHS, National Vital Statistics System, Mortality File Age 45-64 Hispanic 5 Figure 1. Past year initiation of heroin among individuals aged 12 or older, by age group: 2013 6 Source: SAMHSA, Center for Behavioral Health Statistics and Quality, National Survey on Drug Use and Health (NSDUH), 2013. Figure 4. Past year heroin use among individuals aged 12 or older, by age group: 2002 to 2013 7 *Difference between this estimate and the 2013 estimate is statistically significant at the .05 level. Source: SAMHSA, Center for Behavioral Health Statistics and Quality, National Surveys on Drug Use and Health (NSDUHs), 2002 to 2005, 2006 to 2010 (revised March 2012), and 2011 to 2013. Figure 9. Past month illicit drug use among individuals aged 12 or older, by perceived of availability of heroin and age group: 2013 8 *Difference is statistically significant at the .05 level. Source: SAMHSA, Center for Behavioral Health Statistics and Quality, National Survey on Drug Use and Health (NSDUH), 2013. HHS Opioid Strategy March 2015 9 “Opioid drug abuse is a devastating epidemic facing our nation. I have seen firsthand, in my home state of West Virginia, a state struggling with this very real crisis, the impact of opioid addiction. That’s why I’m taking a targeted approach to tackling this issue focused on prevention, treatment and intervention. -- Secretary Burwell HHS Opioid Strategy March 2015 10 Three Priority Areas: • Provide the training, tools and educational resources that health care professionals need to make more informed prescribing decisions. • Increase the use of naloxone. • Use medication-assisted treatment to help lift people out of opioid addiction SAMHSA Strategic Initiatives 11 SAMHSA’s opioid activities are included in the Prevention of Substance Abuse and Mental Illness Strategic Initiative: • Goal: Prevent and reduce prescription drug and illicit opioid misuse and abuse. – – – – – Objective 1: education (health care professionals, public, stakeholders) Objective 2: Comprehensive prevention approaches (including PDMPs and HIEs) Objective 3: Raise awareness (schools, communities, etc.) Objective 4: Prevent/reduce opioid overdoses and deaths. Objective 5: Revise/implement mandatory guidelines for Federal Drug-free Workplace Program SAMHSA’s Public Health Approach: Community-Centric and Science-Based 12 • Prevention Interventions • Treatment & Recovery • Overdose Prevention & Rescue Reduce opioid abuse, dependence, & addiction Improve treatment services & outcomes Increase and sustain recovery Reduce OD & improve OD rescue outcomes Opioid Use Disorders – DSM V 13 The diagnosis of Opioid Use Disorder under DSM V can be applied to someone who uses opioid drugs and has at least two of the following symptoms within a 12 month period: Taking more opioid drugs than intended. Wanting or trying to control opioid drug use without success. Spending a lot of time obtaining, taking, or recovering from the effects of opioid drugs. Cravings opioids. Failing to carry out important roles at home, work or school because of opioid use. Continuing to use opioids, despite use of the drug causing relationship or social problems. Giving up or reducing other activities because of opioid use. Using opioids even when it is physically unsafe. Knowing that opioid use is causing a physical or psychological problem, but continuing to take the drug anyway. Tolerance for opioids. Withdrawal symptoms when opioids are not taken. Health and Mental Health Issues Associated with Heroin Use 14 Heart disease, heart infections, heart failure Kidney disease, kidney failure HIV/AIDS and Hepatitis B or C Impaired immune system resulting in the inability to fight disease and infection Drug overdose Symptoms of withdrawal Decreased libido Relationship problems Legal trouble Inability to perform roles and responsibilities at school, work, home and etc. Financial problems National Rx Drug Abuse Prevention Strategy 15 Prescriber and consumer education/awareness 53 percent of people 12 and older using prescription pain relievers non-medically got them from a friend or relative for free Expanded and enhanced use of prescription drug monitoring programs Education/awareness about safe disposal of unused medicines SAMHSA’s Rx Drug/Opioid Abuse Prevention/Early Intervention Efforts 16 State Partnerships for Success grants Drug Free Communities grants Substance Abuse Block grant Prescription Drug Monitoring Program grants Opioid Overdose Prevention Toolkit Federal Drug-Free Workplace Program SAMHSA/CDC Prescription Drug Abuse Prevention Campaign Consumer Education Screening, Brief Intervention and Referral for Treatment Not Worth the Risk, Even If It’s Legal (pamphlet series) Prescriber Education Continuing medical education PCSS-Opioids and PCSS-MAT National Prescription Drug Abuse Summit Addressing Rx and Opioid Abuse FY 2016 Proposed Prevention Initiatives 17 Preventing Opioid Overdose-Related Deaths: $12 M • • • • Grants to 10 states to reduce # of opioid overdose-related deaths Help states purchase naloxone not otherwise covered Equip first responders in high-risk communities Support education on use of naloxone and other overdose death prevention strategies • Cover expenses incurred from dissemination efforts Addressing Rx and Opioid Abuse FY 2016 Proposed Prevention Initiatives Strategic Prevention Framework for Prescription Drugs (SPF-Rx): $10 M • Raise public awareness about dangers of sharing medications • Work with pharmaceutical and medical communities to raise awareness on risks of overprescribing • Develop capacity and expertise in use of data from state prescription drug monitoring programs (PDMPs) to identify communities by geography and high-risk populations 18 The Treatment Gap 19 Source: 2013 NSDUH Number of Clients Receiving MAT at OTPs & other Facilities 20 3,781 48,148 330,308 Source: N-SSATS Methadone Buprenorphine Vivitrol Primary Substance of Abuse at Admission 21 Opioid Use Disorders and MedicationAssisted Treatment (MAT) 22 “Although [methadone] can be abused, it is rarely a primary drug of abuse. Its therapeutic effectiveness has been clearly demonstrated…” Federal Regulation of Methadone Treatment. Institute of Medicine. 1995. “It is now generally agreed that opiate dependence is a medical disorder and that pharmacologic agents are effective in its treatment. Evidence presented to the panel indicates that availability of these agents is severely limited and that large numbers of patients with this disorder have no access to treatment.” NIH Consensus Statement on Effective Medical Treatment of Opiate Addiction. November 19, 1997. “Medications are an important element of treatment for many patients, especially when combined with counseling and other behavioral therapies.” Principles of Drug Addiction Treatment A Research-Based Guide. National Institute on Drug Abuse October 1999 Opioid Use Disorders and MAT 23 MAT is a direct service that provides a person who has an opioid (heroin) use disorder with pharmacotherapy in conjunction with behavioral therapies as treatment for associated symptoms or disabilities. Treatment is individualized. Medications include methadone, buprenorphine and naltrexone. Methadone can only be dispensed at a SAMHSA certified opioid treatment program (OTP) to a person with an opioid use disorder Source: Psychiatric Services 65:146–157, 2014; doi: 10.1176/appi.ps.201300235 SAMHSA Regulations and Guidelines for OTPs 24 42 CFR Part 8 sets forth requirements for OTPs including mandatory accreditation, DEA registration, state licensure. OTPs are expected to provide access to the full range of FDA approved medications. OTPs must provide recovery support directly or via referral to adequate & accessible community services. Peers are recovering individuals who have experienced the challenges as well as the successes of treatment. Peers often have more credibility and impact than nonpeer clinicians. Addressing Rx and Opioid Abuse FY 2015 Proposed Treatment Initiatives 25 Targeted Capacity Expansion Grant to States for Prescription Drug and Opioid Addiction: • $12M in FY 2015 appropriation • States would focus on high risk communities to address opioid use disorders • 39 states are eligible based on high rates of admission for opioid addiction treatment Addressing Rx and Opioid Abuse FY 2016 Proposed Treatment Initiatives 26 Medication Assisted Treatment (MAT) for Prescription Drug and Opioid Addiction: $13 M • $12M in FY 2015 appropriation • Targeted Capacity Expansion—General Program • Grants to states to focus on high risk communities to address opioid use disorders • Improve access to MAT services for individuals with opioid use disorders MAT Language in FY 2015 Treatment RFAs 27 SAMHSA has added language to the following RFAs to emphasize the use of MAT in broader populations. • • • • Drug Courts Offender Reentry Program State Youth Treatment Implementation Targeted Capacity Expansion – HIV for High Risk populations Recovery 28 MAT is an important component in sustaining recovery. “Medication-Assisted Treatment is a BIG part of my recovery, but staying sober depends on more than just medication. I do service work, go to meetings, stay away from drugs/alcohol, and surround myself with supportive people.”1 - Ian C. Minneapolis, MN 1Legal Action Center (March 2015) Confronting an epidemic: the case for eliminating barriers to medicationassisted treatment of heroin and opioid addiction. www.lac.org Recovery 29 Many Paths, One Future “A process of change Recovery through which individuals improve their health and wellness, live a selfdirected life, and strive to reach their full potential.” Recovery: Health Determinants 30 https://www.healthypeople.gov/2020/topics-objectives/topic/social-determinants-health Recovery: Hope & Hard Work 31 Recovery looks forward; and while it learns lessons from the past, it does not use the past as a metric for the present or as a prognosis for the future. Recovery focuses on an individual’s strengths; on housing, employment, and education; on societal engagement and contribution as well as support; on wellness; and on holistic health. Narcotics Anonymous 32 We make a distinction between drugs used by drug replacement programs and other prescribed drugs because such drugs are prescribed specifically as addiction treatment. Our program approaches recovery from addiction through abstinence, cautioning against the substitution of one drug for another. However, we have absolutely no opinion on methadone maintenance or any other program aimed at treating addiction. NA WORLD SERVICE BOARD OF TRUSTEES BULLETIN #29 Regarding Methadone and Other Drug Replacement Programs Recovery: SAMHSA’s Central Tenets 33 Health: Promote health and recovery-oriented service systems. Home: Ensure that permanent housing and supportive services are available. Purpose: Increase gainful employment and educational opportunities. Community: Promote peer support and the social inclusion (e.g., Peer recovery Support Services, PRSS). 33 Thank you! 34 Questions? [email protected]