Download 36. Risk Management: Brief Intervention (McPherson)

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Transcript
Case ID _____
SBIRT FLO Checklist
PATIENT INFORMATION:
o
o
o
o
o
o
Date _______/_______/_______
Staff Initials of Person Conducting SBIRT _______
Patient Age ______ yrs old
Patient Sex/Gender _______
Patient Race ________
Patient Health Plan/Payer Source ________________________ (if no insurance, write in “uninsured”)
OPENING
<1 minute
_______ Identify self and role on the team
______ Get patient’s permission to talk to them for a few minutes:
o I’d like to ask you some personal questions.
o Your answers are completely confidential.
o You don’t have to answer if you feel uncomfortable.
o We ask everyone these questions so we can provide the best care.
_______ REFUSED screening
PRESCREEN (AUDIT-C):
Questions
0
1
2
1. How often do you have a drink
Never
Monthly
2-4 times
containing alcohol?
or less
per month
2. How many drinks containing
alcohol do you have on a typical day
1 or 2
3 or 4
5 or 6
of drinking?
3. How often do you have five or
Never
Less than
Monthly
more drinks on one occasion?
monthly
Scoring: 4+ for men and 3+ for women = positive alcohol screen for
hazardous use.
3
2-3 times
per week
4
4 or more
times per week
7 to 9
Weekly
10 +
Daily or
almost daily
Add items 1-3
PRESCREEN (DAST-2):
1-2 minutes
Questions
1. Have you used drugs other than
those required for medical reasons?
1-3 minutes
Score
0
No
2. Do you abuse more than one drug
No
at a time?
Scoring: 1+ for men and women = positive drug prescreen for
risky use.
1
Score
Yes
Yes
Add items 1-2
Recommended Level and Focus of Brief Intervention based on Screening Results:

NEGATIVE SCREEN
Inform client they screened negative for hazardous alcohol/drug use and are at low risk for health and other problems.

Congratulate clients and encourage them to remain that way.

Simple Advice can be offered. –STOP HERE

POSITIVE SCREEN 
Inform client they screened positive for hazardous alcohol/drug use and are at risk for health and other problems.

Provide BI.

Conduct Referral.
BRIEF INTERVENTION: For patients who screen positive.
_______ REFUSED Brief Intervention (check here is patient refuses BI at any point after screening)
_______
PURPOSE OF THIS SESSION is to:
1) Give you information about your drinking/drug use
2) Get your opinion about your drinking/drug use
3) Talk about what if anything you want to change about your drinking/drug use
Case ID _____
“F” FEEDBACK USING BAC (Blood Alcohol Concentration) [Adapt for OTHER BIOASSAYS, e.g., urine)]
______
______
______
______
______
______
Range: BAC can range from 0 (sober) to .4 (lethal)
Anybody knows: .08 defines drunk driving, which is actually heavy drinking
Normal drinking: is .03-.05
Give result: Your BAC was…
Elicit reaction: What do you make of that?
“WHAT ROLE IF ANY DO YOU THINK ALCOHOL PLAYED IN YOUR ______ (e.g., injury, getting arrested)?”
“F” FEEDBACK USING AUDIT-C
______
______
______
______
______
‘L’
1-2 minutes
[Adapt for DAST-2]
1-2 minutes
Range: AUDIT-C can range from 0 (non-drinkers) to 12 (hazardous, harmful, risk use of alcohol)
AUDIT has been given to thousands of people, so you can compare your drinking to others.
Normal AUDIT-C scores are 0-4 for men and 0-3 for women, which is low-risk drinking
Give result: Your score was…which places you in the category for higher risk of harm.
Elicit reaction: What do you make of that?
LISTEN AND ELICIT
1-5 minutes
______ Explore pros and cons of drinking/drug use (What do you like about drinking/drug use? What do like less about drinking/drug
use?)
______ Summarize both sides (On the one hand…On the other hand…)
______ Ask about importance. (circle #) On a scale of 1-10, how important is it to you to… (change)? Why did you give it that number
and not a lower number? What would it take to raise that number?
(Not at all Important) 1 – 2 – 3 – 4 – 5 – 6 – 7 – 8 – 9 – 10 (Very Important)
______ Ask about confidence. (circle #) On a scale of 1-10, how confident are you that you can change successfully? Why did you give
it that number and not a lower number? What would it take to raise that number?
(Not at all Confident )1 – 2 – 3 – 4 – 5 – 6 – 7 – 8 – 9 – 10 (Very Confident)
“O” OPTIONS (Goal Setting)
1-5 minutes
_______ Ask key questions: WHAT do you want to change? WHAT is your goal?
(Offer MENUS of Options below)
_______
Manage your drinking/drug use
_______
Eliminate drinking/drug use from your life
_______
Never drink/use drugs and drive
_______
Utterly nothing
_______
Seek help
_______
Other goals __________________________________________________________________________
_______ If goal is set, ASK about the plan
(How will you do that? Who will help you? What might get in the way?)
CLOSE ON GOOD TERMS
<1 minute
______ Summarize patient’s statements in favor of change
______ Emphasize their strengths
EDUCATION & REFERRAL
______
______
______
<1 minute
Give patient education brochures (e.g., “Rethinking Drinking: Alcohol and Your Health”)
Give referral based on payer (i.e., health plan, self/uninsured)
Identify referral resource (e.g., staff psychiatrist, health educator, social worker), specify here________________________
_______ THANK PATIENT for speaking with you.
Recommended Reference: McPherson, T.L. & Goplerud, E. (March, 2014) FLO SBIRT Checklist. BIG Initiative: Spartanburg, SC training handout. For more
information: Contact Dr. Tracy McPherson at NORC at the University of Chicago at [email protected] or visit http://bigsbirteducation.webs.com and
http://hospitalsbirt.webs.com.
Harmful
Interactions
mixing alcohol
with medicines
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o
Harmful
interactions
You’ve probably seen this warning on medicines you’ve taken.
The danger is real. Mixing alcohol with certain medications can
cause nausea and vomiting, headaches, drowsiness, fainting, or
loss of coordination. It also can put you at risk for internal
bleeding, heart problems, and difficulties in breathing. In addition
to these dangers, alcohol can make a medication less effective
or even useless, or it may make the medication harmful or
toxic to your body.
Some medicines that you might
never have suspected can react with
alcohol, including many medications
which can be purchased “over-thecounter”—that is, without a prescription.
Even some herbal remedies can
have harmful effects when combined
with alcohol.
This pamphlet lists medications
that can cause harm when taken with
alcohol and describes the effects that
can result. The list gives the brand
name by which each medicine is
commonly known (for example,
Benadryl ® ) and its generic name or
active ingredient (in Benadryl ® , this
is diphenhydramine). The list
presented here does not include all
the medicines that may interact
harmfully with alcohol. Most important, the list does not include all
the ingredients in every medication.
1
Medications typically are safe and
effective when used appropriately.
Your pharmacist or other health care
provider can help you determine
which medications interact harmfully
with alcohol.
D I D YO U K N OW …
Mixing alcohol and medicines can
be harmful. Alcohol, like some medicines, can make you sleepy, drowsy,
or lightheaded. Drinking alcohol
while taking medicines can intensify
these effects. You may have trouble
concentrating or performing mechanical skills. Small amounts of
alcohol can make it dangerous to
drive, and when you mix alcohol with
certain medicines you put yourself at
even greater risk. Combining alcohol
with some medicines can lead to falls
and serious injuries, especially among
older people.
MEDICINES MAY HAVE
MANY INGREDIENTS
Some medications—including many
popular painkillers and cough, cold,
and allergy remedies—contain more
than one ingredient that can react
with alcohol. Read the label on the
medication bottle to find out exactly
what ingredients a medicine contains.
Ask your pharmacist if you have any
questions about how alcohol might
interact with a drug you are taking.
2
SOME MEDICINES
CONTAIN ALCOHOL
Certain medicines contain up to 10
percent alcohol. Cough syrup and
laxatives may have some of the highest alcohol concentrations.
ALCOHOL AFFECTS
WOMEN DIFFERENTLY
Women, in general, have a higher
risk for problems than men. When a
woman drinks, the alcohol in her
bloodstream typically reaches a higher
level than a man’s even if both are
drinking the same amount. This is
because women’s bodies generally
have less water than men’s bodies. Because alcohol mixes with body water,
a given amount of alcohol is more
concentrated in a woman’s body than
in a man’s. As a result, women are
more susceptible to alcohol-related
damage to organs such as the liver.
OLDER PEOPLE FACE
GREATER RISK
TIMING IS IMPORTANT
Older people are at particularly
high risk for harmful alcohol–
medication interactions. Aging slows
the body’s ability to break down
alcohol, so alcohol remains in a
person’s system longer. Older people
also are more likely to take a
medication that interacts with
alcohol—in fact, they often need
to take more than one of these
medications.
Alcohol and medicines can interact
harmfully even if they are not taken
at the same time.
REMEMBER...
Mixing alcohol and medicines puts
you at risk for dangerous reactions.
Protect yourself by avoiding alcohol if
you are taking a medication and don’t
know its effect. To learn more about
a medicine and whether it will interact with alcohol, talk to your pharmacist or other health care provider.
Commonly Used Medicines (Both Prescription and Over-the-Counter)
That Interact With Alcohol
Symptoms/
Disorders
Medication
(Brand name)
Medication
(Generic name)
Allergies/
colds/flu
• Alavert®
• Atarax®
• Benadryl®
• Clarinex®
• Claritin®,
Claritin-D®
• Dimetapp®
Cold & Allergy
• Sudafed®
Sinus & Allergy
• Triaminic®
Cold & Allergy
• Tylenol®
Allergy Sinus
• Tylenol®
Cold & Flu
• Zyrtec®
Loratadine
Hydroxyzine
Diphenhydramine
Desloratadine
Loratadine
Angina
• Isordil®
(chest pain),
coronary
heart disease
Some possible
reactions with alcohol
Drowsiness,
dizziness;
increased risk
for overdose
Brompheniramine
Chlorpheniramine
Chlorpheniramine
Chlorpheniramine
Chlorpheniramine
Cetirizine
Isosorbide
Nitroglycerin
Rapid heartbeat,
sudden changes
in blood pressure,
dizziness, fainting
3
Commonly Used Medicines (Both Prescription and
Symptoms/
Disorders
Anxiety
and
epilepsy
Medication
(Brand name)
• Ativan®
• BuSpar®
• Klonopin®
• Librium®
• Paxil®
• Valium®
• Xanax®
Medication
(Generic name)
Some possible
reactions with alcohol
Lorazepam
Buspirone
Clonazepam
Chlordiazepoxide
Paroxetine
Diazepam
Alprazolam
Drowsiness, dizziness;
increased risk for
overdose; slowed or
difficulty breathing;
impaired motor control;
unusual behavior;
memory problems
• Herbal preparations
(Kava Kava)
4
Liver damage,
drowsiness
Arthritis
• Celebrex®
• Naprosyn®
• Voltaren®
Celecoxib
Naproxen
Diclofenac
Ulcers, stomach
bleeding, liver
damage
Attention and
concentration
(Attention
deficit/
hyperactivity
disorder)
• Adderall ®
Amphetamine/
dextro-amphetamine
Methylphenidate
Dizziness, drowsiness,
impaired concentration
(methylphenidate,
dexmethylphenidate);
possible increased risk
for heart problems
(amphetamine, dextroamphetamine, lisdexamfetamine); liver
damage (atomoxetine)
• Concerta ®,
Ritalin ®
• Dexedrine ®
• Focalin ®
• Strattera ®
• Vyvanse ®
Dextroamphetamine
Dexmethylphenidate
Atomoxetine
Lisdexamfetamine
Warfarin
Occasional drinking
may lead to internal
bleeding; heavier
drinking also may
cause bleeding or
may have the opposite
effect, resulting in
possible blood clots,
strokes, or heart attacks
Blood clots
• Coumadin®
Cough
Dextromethorpan
Drowsiness, dizziness;
• Delsym®,
increased risk
Robitussin Cough®
Guaifenesin + codeine for overdose
• Robitussin A–C®
Over-the-Counter) That Interact With Alcohol
Symptoms/
Disorders
Depression
Diabetes
Enlarged
prostate
Medication
(Brand name)
Medication
(Generic name)
• Abilify®
Aripriprazone
• Anafranil®
Clomipramine
Citalopram
• Celexa®
• Clozaril®
Clozapine
Duloxetine
• Cymbalta®
• Desyrel®
Trazodone
Venlafaxine
• Effexor®
Amitriptyline
• Elavil®
• Geodon®
Ziprasidone
Paliperidone
• Invega®
®
• Lexapro
Escitalopram
Fluvoxamine
• Luvox®
Phenelzine
• Nardil®
Desipramine
• Norpramin®
®
• Parnate
Tranylcypromine
• Paxil®
Paroxetine
• Pristiq®
Desevenlafaxine
• Prozac®
Fluoxetine
• Remeron®
Mirtazapine
Risperidone
• Risperdal®
Quetiapine
• Seroquel®
• Serzone®
Nefazodone
• Symbyax®
Fluoxetine/Olanzapine
• Wellbutrin®
Bupropion
Sertraline
• Zoloft®
Olanzapine
• Zyprexa
• Herbal preparations
(St. John’s Wort)
• Diabinese®
• Glucotrol®
• Glucophage®
• Glynase®,
DiaBeta®,
Micronase®
• Orinase®
• Tolinase®
Chlorpropamide
Glipizide
Metformin
Glyburide
• Cardura®
• Flomax®
• Hytrin®
• Minipress®
Doxazosin
Tamsulosin
Terazosin
Prazosin
Tolbutamide
Tolazamide
Some possible
reactions with alcohol
Drowsiness, dizziness;
increased risk for overdose;
increased feelings of
depression or hopelessness
(all medications); impaired
motor control (quetiapine,
mirtazapine); increased
alcohol effect (bupropion);
liver damage (duloxetine)
Monoamine oxidase
inhibitors (MAOIs),
such as tranylcypromine
and phenelzine, when
combined with alcohol,
may result in serious heartrelated side effects. Risk for
dangerously high blood
pressure is increased when
MAOIs are mixed with
tyramine, a byproduct
found in beer and red wine
Abnormally low blood sugar
levels, flushing reaction
(nausea, vomiting,
headache, rapid heartbeat,
sudden changes in blood
pressure); symptoms of
nausea and weakness may
occur (metformin)
Dizziness, light
headedness, fainting
5
Commonly Used Medicines (Both Prescription and
Symptoms/
Disorders
Medication
(Brand name)
Some possible
reactions with alcohol
Heartburn, • Axid®
indigestion, • Reglan®
sour stomach • Tagamet®
• Zantac®
Nizatidine
Metoclopramide
Cimetidine
Ranitidine
Rapid heartbeat; increased
alcohol effect; sudden
changes in blood pressure
(metoclopramide)
High blood
pressure
• Accupril®
• Calan®
• Capozide®
• Cardura®
• Catapres®
• Cozaar®
• Hytrin®
• Lopressor® HCT
• Lotensin®
• Minipress®
• Norvasc®
• Prinivil®,
Zestril®
• Vaseretic®
Quinapril
Verapamil
Hydrochlorothiazide
Doxazosin
Clonidine
Losartan
Terazosin
Hydrochlorothiazide
Benzapril
Prazosin
Amlodipine mesylate
Lisinopril
Dizziness, fainting,
drowsiness; heart
problems such as changes
in the heart’s regular
heartbeat (arrhythmia)
• Advicor®
• Altocor®
• Crestor®
• Lipitor®
• Mevacor®
• Niaspan®
• Pravachol®
• Pravigard™
Liver damage (all
medications); increased
flushing and itching
(niacin), increased
stomach bleeding
(pravastatin + aspirin)
• Zocor®
Lovastatin + Niacin
Lovastatin
Rosuvastatin
Atorvastatin
Lovastatin
Niacin
Pravastatin
Pravastatin +
Aspirin
Ezetimibe +
Simvastatin
Simvastatin
• Acrodantin®
• Flagyl®
• Grisactin®
• Nizoral®
• Nydrazid®
• Seromycin®
• Tindamax®
• Zithromax®
Nitrofurantoin
Metronidazole
Griseofulvin
Ketoconazole
Isoniazid
Cycloserine
Tinidazole
Azithromycin
Fast heartbeat, sudden
changes in blood
pressure; stomach pain,
upset stomach, vomiting,
headache, or flushing or
redness of the face; liver
damage (isoniazid,
ketoconazole)
High
cholesterol
• Vytorin™
Infections
6
Medication
(Generic name)
Enalapril
Over-the-Counter) That Interact With Alcohol
Symptoms/
Disorders
Mood
stabilizers
Medication
(Brand name)
• Depakene®,
Depakote®
• Eskalith®,
Eskalith®CR,
Lithobid
Medication
(Generic name)
Valproic acid
Lithium
Some possible
reactions with alcohol
Drowsiness, dizziness;
tremors; increased risk for
side effects, such as restlessness, impaired motor
control; loss of appetite;
stomach upset; irregular
bowel movement; joint or
muscle pain; depression;
liver damage (valproic acid)
Muscle pain • Flexeril®
• Soma®
Cyclobenzaprine
Carisoprodol
Drowsiness, dizziness;
increased risk of seizures;
increased risk for overdose;
slowed or difficulty
breathing; impaired motor
control; unusual behavior;
memory problems
Nausea,
motion
sickness
Meclizine
Dimenhydrinate
Promethazine
Drowsiness, dizziness;
increased risk for overdose
Pain
• Advil®
(such as
• Aleve®
muscle ache, • Excedrin®
minor arthritis
pain), fever, • Motrin®
inflammation • Tylenol®
Ibuprofen
Naproxen
Aspirin,
Acetaminophen
Ibuprofen
Acetaminophen
Stomach upset, bleeding
and ulcers; liver damage
(acetaminophen); rapid
heartbeat
Seizures
Phenytoin
Gabapentin
Drowsiness, dizziness;
increased risk of seizures
(levetiracetam, phenytoin);
unusual behavior and
changes in mental health
(such as thoughts of
suicide) (topiramate)
• Antivert®
• Dramamine®
• Phenergan®
• Dilantin®
• Horizant®,
Neurontin®
• Keppra®
• Klonopin®
• Lamictal®
• Lyrica®
• Tegretol®
• Topamax®
• Trileptal®
Levetiracetam
Clonazepam
Phenobarbital
Lamotrigine
Pregabalin
Carbamazepine
Topiramate
Oxcarbazepine
Barbiturates
7
Commonly Used Medicines (Both Prescription and Over-the-Counter)
That Interact With Alcohol
Symptoms/
Disorders
8
Medication
(Brand name)
Medication
(Generic name)
Some possible
reactions with alcohol
Drowsiness, dizziness;
Propoxyphene
increased risk for overdose;
Merepidine
Butalbital + codeine slowed or difficulty
breathing; impaired motor
control; unusual behavior;
Oxycodone
memory problems
Hydrocodone
Severe pain
from injury,
postsurgical
care, oral
surgery,
migraines
• Darvocet–N®
• Demerol®
• Fiorinal®
with codeine
• Percocet®
• Vicodin®
Sleep
problems
Zolpidem
• Ambien®
Eszopiclone
• Lunesta™
Estazolam
• Prosom™
®
Temazepam
• Restoril
Diphenhydramine
• Sominex®
Doxylamine
• Unisom®
• Herbal
preparations
(chamomile,
valerian, lavender)
Drowsiness, sleepiness,
dizziness; slowed or
difficulty breathing; impaired
motor control; unusual
behavior; memory problems
Increased drowsiness
Additional
resources
MedlinePlus
A service of the U.S. National Library
of Medicine and the National Institutes
of Health.
http://www.nlm.nih.gov/medlineplus/
druginformation.html
Provides information on prescription and
over-the-counter medications.
National Institute on Alcohol Abuse
and Alcoholism
http://www.niaaa.nih.gov
Phone number: 301–443–3860
Makes available free informational
materials on alcohol use, alcohol abuse,
and alcoholism.
U.S. Food and Drug Administration
Center for Drug Evaluation and Research
http://www.fda.gov/cder
Phone numbers:
• Main FDA for general inquiries:
1–888–INFO–FDA (1–888–463–6332)
• Drug Information: 301–827–4570
• To submit a report about Adverse
Drug Reaction: Medwatch:
1–800–FDA–1088
Provides information on prescription
and over-the-counter medications,
consumer drug information, and reports
and publications.
9
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
NIH . . . Turning Discovery Into Health
NIH Publication No. 13–5329
Published 2003
Revised 2014
Guideline for Tobacco Cessation and Secondhand Smoke Exposure
Evidence indicates that patients are more likely to quit tobacco when clinicians intervene.
• Integrate interventions for tobacco cessation and secondhand smoke exposure reduction into every interaction with the patient by using the 5As approach.
• Utilize a combination of behavioral change counseling (including the Colorado QuitLine) and pharmacotherapy treatments for the highest rates of abstinence success.
• Inform about the health risks of secondhand smoke exposure - especially children; encourage the establishment of smoke-free environments.
Tobacco dependence (current or former) is a chronic relapsing disease that requires a systematic approach
and may require repeated clinician interventions for multiple patient quit attempts.
ASK
ASK
• ASK every patient at each encounter about tobacco use and document status.
»» If patient recently quit using tobacco, reassess abstinence status, address possible relapse, and congratulate success.
• ASK the patient if they are exposed to secondhand smoke, or if the person who cares for their children smokes.
ADVISE
ARRANGE
ADVISE
ASSIST
ASSESS
If you have limited time:
ASK
ADVISE
REFER
• ADVISE every tobacco user to quit smoking with a clear, strong and personalized health message about the benefits of
quitting.
• Discuss the health risks of secondhand smoke exposure on household members, especially children, and ADVISE them to
always smoke outside and to create smoke-free home and car environments.
ASSESS
• ASSESS the willingness to make a quit attempt within the next 30 days:
»» If willing, proceed to the next step: “ASSIST”
»» If not willing, use strategies of empathy, listening reflectively and open ended questions to enhance patient’s motivation
to quit:
»» Address the appropriate 5 Rs with encouragement and support self-reliance in a non-confrontational manner:
›› Relevance - search for patient’s personal important reason(s) to quit
›› Risk - ask patient to identify what are the harms to continued tobacco use
›› Rewards - have patient talk about benefits of quitting
›› Roadblocks - have patient discuss barriers and fears to quitting
›› Repetition - review the relevant 5 Rs at each visit
ASSIST
• ASSIST by referring the patient to the Colorado QuitLine at 1-800-QUIT-NOW (1-800-784-8669) and/or
• Provide positive practical behavioral coaching as part of a quit plan:
»» Practical problem solving and coping skills training
›› Discuss cessation tips: set a quit date, create smoke-free environments, avoid high risk situations, and identify triggers
›› Provide tailored self-help materials for cessation and reducing secondhand smoke exposure
›› Establish a system of self-rewarding success (e.g.: money saved, improved sense of taste)
»» Social support:
›› Use encouragement, communicate caring and concern, assist with establishing support of friends and family
• Offer tailored pharmacotherapy treatments (see reverse side).
• AGREEMENT: collaboratively set specific quit goals and address barriers (e.g.: weight gain, fear of failure).
ARRANGE
1-800-QUIT-NOW
1-800-784-8669
Additional Resources:
• ARRANGE a follow-up contact within the first week after the quit date or QuitLine referral and a second follow-up contact
within the first month.
• Ongoing monitoring for relapse; if relapse occurs, reassure this is normal and use lapse as a learning experience, identify
triggers and plan next quit attempt.
• Congratulate successes!
Reference:
• CCGC Website: www.coloradoguidelines.org/tobacco
• Free office toolkits and materials: www.cohealthresources.com
• Colorado QuitLine: 1-800-QUIT-NOW (1-800-784-8669) or www.myquitpath.org
• Provider Website: www.cohealthproviders.com
• Surgeon General’s Website: www.surgeongeneral.gov/tobacco/
For important updates, special clinical considerations, additional information and copies of the guideline, email CCGC at
[email protected] OR call (720) 297-1681 OR (866) 401-2092.
This guideline is designed to assist clinicians in the management of patients with tobacco use and/or secondhand smoke exposure.
This guideline is not intended to replace a clinician’s judgment or establish a protocol for all patients with a particular condition.
www.coloradoguidelines.org/tobacco
Funded with proceeds from the 2004 state tobacco excise tax
Pharmacotherapy Treatments: Tobacco Cessation Medication Classification and Dosages
Category
Drugs
Recommended Dosage
Tobacco use should be approached as a chronic relapsing disease.
Pharmacotherapy should be offered for all patients attempting to quit smoking except when contraindicated.
The average smoker has multiple attempts to quit before successful abstinence.
Combination therapy options: Nicotine patch + other NRT or Nicotine patch + Bupropion SR
Current evidence is insufficient and risk/benefits should be discussed with these patients:
light smokers, adolescents, smokeless tobacco users, and pregnant patients.
Recommended
Duration
Relative Cost
Index:
1ppd = $$
(av $150/mo)
NRT (nicotine
replacement
therapy)
Nicotine Patch/transdermal
(NicoDerm CQ,
Habitrol, Nicotrol)
> 10 cigs/day: use 21 mg/24 hrs for
6-8 wks, then 14 mg/24 hrs for 2-4
weeks, then 7mg/24 hrs for
2-4 weeks
Up to 10 weeks
< 10 cigs/day: use 15 mg/16 hrs for
6 weeks
Nicotine Gum (Nicorette)
1-24 cigs/day: 2 mg gum
(every 1- 2 hrs up to 24 pieces/day)
25+ cigs/day: 4 mg gum (every
1- 2 hrs up to 24 pieces/day)
Up to 12 weeks
Contraindications/Precautions
Consult package insert for full list of precautions,
contraindications, use in pediatrics, and drug interactions
Adverse Side Effects/Treatment Tips
These are general categories;
individual patient reactions may vary
Pregnancy (weigh
risk vs. benefit)
•
•
•
•
•
OTC
$
Available
from QuitLine
with program
enrollment
Contraindicated:
• Recent (</= 2 weeks) myocardial infarction,
• severe arrhythmias,
• unstable angina
Precautions:
• TMJ disease
• Local skin reaction
• Insomnia, abnormal or change in dreams
• Headache
• GI nausea, gas, dyspepsia, constipation
Cat D
OTC
$$$
Contraindicated:
• Recent (</= 2 weeks) myocardial infarction,
• severe arrhythmias,
• unstable angina
• Jaw pain, mouth or throat soreness, throat nasal and
mouth irritation
• Insomnia, abnormal or change in dreams
• GI nausea, gas, dyspepsia, constipation
Cat C
Contraindicated:
• Recent (</= 2 weeks) myocardial infarction,
• severe arrhythmias,
• unstable angina
• Jaw pain, mouth or throat soreness, throat nasal and
mouth irritation
• Headache
• GI nausea, gas, dyspepsia, constipation
Cat D
Cat D
No food or drink 15 minutes before use
“Chew and Park” technique
Nicotine Lozenge (Commit)
2 mg for those who smoke their
first cigarette more than 30 min
after waking
4 mg for those who smoke their
first cigarette within 30 min of
waking
Up to 12 weeks:
wks 1- 6: 1 loz/ 1-2 hrs
wks 7-9: 1 loz/ 2-4 hrs
wk 10-12: 1 loz/ 4-8 hrs
OTC
$$$
No food or drink 15 min before use
Nicotine Oral Inhaler
(Nicotrol Inhaler)
6-16 cartridges/day; puff each
cartidge for up to 20 minutes
Each cartridge 4 mg
10 puffs inhaler=1 puff cigarette
Medications
prescription
$$$
Contraindicated:
• Recent (</= 2 weeks) myocardial infarction,
• severe arrhythmias,
• unstable angina
• Jaw pain, mouth or throat soreness, throat nasal and
mouth irritation
• Headache
Nicotine Nasal Spray
(Nicotrol NS)
8-40 sprays/day: 1 dose = 1 spray/
nostril
1-2 doses/ hr (maximum 5 doses/hr
or < 40 doses/day)
Up to 3 - 6 months
prescription
$$
Contraindicated:
• Recent (</= 2 weeks) myocardial infarction,
• severe arrhythmias,
• unstable angina
Precautions:
• Severe reactive airway disease
• Underlying chronic nasal disorders (rhinitis, nasal polyps, sinusitis)
• Jaw pain, mouth or throat soreness, throat nasal and
mouth irritation
• GI nausea, gas, dyspepsia, constipation
Bupropion SR (Zyban)
150 mg/day for 3 days, then 150
mg/day
BID from day 4 to end of treatment
(begin treatment 1-2 weeks
pre-quit)
Up to 12 weeks
Maintenance up
to 6 months
prescription
$$
Contraindicated:
• Patients with seizure disorders, bulimia or anorexia nervosa (eating
disorders)
• Patients with bipolar and schizophrenia, MAO use within previous
14 days
• Simultaneous abrupt discontinuation of alcohol or sedatives
• Suicide risk (Black box warning): increased in children, adolescents,
and young adults
• Insomnia, abnormal or change in dreams
• Headache
0.5 mg/day on days 1-3, 0.5 mg BID
on days 4-7, then 1 mg BID from
day 8 to end of treatment
(begin treatment 7 days pre-quit
date)
12 weeks treatment:
may consider additional
12 weeks to enhance
cessation
prescription
$
Warning/precaution:
• Renal impairment, dialysis, psychiatric condition
• Serious psychiatric illness: monitor frequently for depressed mood,
agitation, changes in behavior, suicidal ideation and suicide
• Monitor neuropsychiatric symptoms
• Use caution driving or operating machinery until you know how
quitting smoking and/or using CHANTIX may affect you.
• Insomnia, abnormal, strange or vivid dreams
• Headache
• GI nausea, gas, dyspepsia, constipation
Varenicline (Chantix)
Reference:
6-16 cartridges/day;
puff each cartidge for
up to 20 minutes
Each cartridge 4 mg
Treating Tobacco Use and Dependence; US Department of Health and Human Services Public Health Service, 2008
For important updates, special clinical considerations, and effectiveness information, visit www.coloradoguidelines.org/tobacco
3rd revision: 5/2009
2nd revision: 2/2007
1st revision: 11/2004
Original: 9/2002
Cat D
Cat C
Cat C
Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
SECTION 1: Screening and Monitoring Instruments
The PHQ2/9 can be effectively used to screen for depression with adolescents, adults, and seniors. The additional
screens offer greater sensitivity for select populations and psychiatric conditions.
PHQ-2/9 (Patient Health Questionnaire)
PHQ-2: The first two questions of the PHQ-9 are recommended as the first step to screen for current depression.
It can be administered orally or self-administered on a written form. It may be scored as a “yes/no” questionnaire
or using a Likert scale to assess symptom frequency.
Scoring the PHQ-2:
A positive score is:
1. “Yes” to either question; or
2. A score >3 using the Likert scale (which is aligned with the PHQ-9 scoring criteria):
Over the past two weeks, how often have you been bothered by any of the following problems?
2. Feeling down, depressed, or hopeless.
1. Little interest or pleasure in doing things.
0 = Not at all
0 = Not at all
1 = Several days
1 = Several days
2 = More than half the days
2 = More than half the days
3 = Nearly every day
3 = Nearly every day
Total point score:_______________
A patient with a positive PHQ-2 should complete the full PHQ-9.
PHQ-9: This 9-item questionnaire to assess symptoms of depression during the past two weeks scores each of
the 9 DSM-IV criteria and is derived from the Primary Care Evaluation of Mental Disorders (PRIME-MD) diagnostic
tool. The PHQ-9 is available in more than 80 languages and no permissions or cost are required to use it.
Download at: http://www.phqscreeners.com
The PHQ-9 can also be downloaded at: http://www.healthteamworks.org/guidelines/depression.html
Recommended use:
• To assess symptoms and functional impairment and make a tentative diagnosis of depression
• To assess severity of depressive symptoms and assist with treatment planning
• To monitor treatment effectiveness
• May be self-administered on a written form or administered orally by a member of the healthcare practice
team
Scoring the PHQ-9:
• Instructions are included on the PHQ-9 form.
• It is simple to score by hand and can be embedded in an EHR.
• Question #9 (about self harm) should always be reviewed before the patient leaves the clinic.
page 1
Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
Suicide Risk Assessment
The Suicide Assessment Five-step Evaluation and Triage (SAFE-T) was adapted from the American Psychiatric
Association Practice Guidelines for the Assessment and Treatment of Patients with Suicidal Behaviors and
developed with funding from SAMHSA.
Available free at: http://www.stopasuicide.org/downloads/Sites/Docs/SAFE-T_One_Page_Final.pdf
Edinburgh Postnatal Depression Scale
The 10-question Edinburgh Postnatal Depression Scale (EPDS) is a validated screening tool to identify patients
at risk for perinatal depression. It is available in multiple languages.
To download the scale in English: http://www.aap.org/practicingsafety/toolkit_resources/module2/epds.pdf
Spanish version: http://steppingup.washington.edu/keys/documents/EPDSSpan.pdf
Geriatric Depression Scale
This questionnaire was developed as a basic screening measure for depression in older adults. It is in the public
domain and available in multiple languages.
Download at: http://www.stanford.edu/~yesavage/GDS.html
Cornell Scale for Depression in Dementia
Depression and dementia frequently co-occur. This screening tool assesses signs and symptoms, and utilizes
a comprehensive interviewing and observational approach that derives information from the patient and the
informant.
To download the scale and a guide to administration and scoring:
http://healthteamworks-media.precis5.com/depression-in-dementia-cornell-scale
Assessment of Bipolar Disorder
Patients with bipolar disorder are more likely to seek care for their depressive states than for their manic or
hypomanic states. Differentiating between unipolar depression and bipolar depression is important because
starting antidepressant medication in a person who has bipolar depression can be destabilizing (it may
contribute to increased anxiety /hypermania) and because failure to detect the bipolar depression means
that the person is less likely to receive the appropriate treatment for that condition. The initial assessment of
depression should include questions about a history of bipolar depression/mania. The MDQ is a screening tool
for bipolar disorder. Note that there is a cost associated with using the MDQ. For additional information and to
order copies go to: www.jblearning.com.
To view the MDQ go to: http://www.dbsalliance.org/pdfs/MDQ.pdf
page 2
Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
Assessment of Generalized Anxiety Disorder (GAD)
The GAD-7 is from the Primary Care Evaluation of Mental Disorders (PRIME-MD), a diagnostic tool containing
modules on 12 different mental health disorders.
It can be downloaded and used at no cost from: http://www.phqscreeners.com/
Screening Brief Intervention Referral to Treatment (SBIRT) Guideline
This guideline summarizes screening and appropriate intervention for risky/unhealthy use of alcohol, tobacco,
and illicit or prescription drugs.
Developed by HealthTeamWorks and available at: http://www.healthteamworks.org/guidelines/sbirt.html
Post Traumatic Stress Disorder Screening
The Primary Care PTSD Screen (PC-PTSD) is a 4-question screening tool designed for use in primary care and
other settings and is also currently used to screen veterans for PTSD at the VA. The introductory (first) question
cues the respondent to traumatic events that they may have experienced. In most cases, the screen should be
considered “positive” if a patient answers “yes” to any of the three items. Individuals with a positive screen should
be assessed with a structured assessment such as the Posttraumatic Stress Disorder Checklist for Civilians
(PCL-C).
PC-PTSD: http://www.ptsd.va.gov/professional/pages/assessments/pc-ptsd.asp
PCL-C in English (includes scoring info.): http://www.pdhealth.mil/guidelines/downloads/PCL_Primer.pdf
PCL-C in Spanish: http://healthteamworks-media.precis5.com/pcl-spanish
PTSD CheckList – Civilian Version (PCL-C)
The PCL is a standardized self-report rating scale for PTSD comprising 17 items that correspond to the key
symptoms of PTSD. Two versions of the PCL exist: 1) PCL-M is specific to PTSD caused by military experiences
and 2) PCL-C is applied generally to any traumatic event. The PCL can be easily modified to fit specific time
frames or events. For example, instead of asking about “the past month,” questions may ask about “the past
week” or be modified to focus on events specific to a deployment.
How is the PCL completed?
• The PCL is self-administered
• Respondents indicate how much they have been bothered by a symptom over the past month using a 5-point
(1–5) scale, circling their responses. Responses range from 1 Not at All – 5 Extremely
How is the PCL Scored?
1) Add up all items for a total severity score, or
2) Treat response categories 3–5 (Moderately or above) as symptomatic and responses 1–2 (below Moderately)
as non-symptomatic, then use the following DSM criteria for a diagnosis:
- Symptomatic response to at least 1 “B” item (Questions 1–5),
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Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
- Symptomatic response to at least 3 “C” items (Questions 6–12), and
- Symptomatic response to at least 2 “D” items (Questions 13–17)
Are Results Valid and Reliable?
Two studies of both Vietnam and Persian Gulf theater veterans show that the PCL is both valid and reliable
Adverse Childhood Experiences
The Adverse Childhood Experiences (ACE) Study is an ongoing collaboration between the Centers for Disease
Control and Prevention and Kaiser Permanente. It is analyzing the relationship between multiple categories
of childhood trauma and health and behavioral outcomes later in life. To read about the study: http://www.
acestudy.org/
What’s an ACE?
Growing up experiencing any of the following conditions in the household prior to age 18:
1. Recurrent physical abuse
2. Recurrent emotional abuse
3. Contact sexual abuse
4. An alcohol and/or drug abuser in the household
5. An incarcerated household member
6. Someone who is chronically depressed, mentally ill, institutionalized, or suicidal
7. Mother is treated violently
8. One or no parents
The ACE Study used a simple scoring method to determine the extent of each study
participant’s exposure to childhood trauma. Exposure to one category (not incident) of ACE,
qualifies as one point. When the points are added up, the ACE Score is achieved.
The ACE study found that persons who had experienced four or more categories of childhood exposure,
compared to those who had experienced none, had 4- to 12-fold increased health risks for alcoholism, drug
abuse, depression, and suicide attempt; a 2- to 4-fold increase in smoking, poor self-rated health, ≥50 sexual
intercourse partners, and sexually transmitted disease; and a 1.4- to 1.6-fold increase in physical inactivity and
severe obesity. The number of categories of adverse childhood exposures showed a graded relationship to the
presence of adult diseases including ischemic heart disease, cancer, chronic lung disease, skeletal fractures, and
liver disease (1998; American Journal of Preventive Medicine).
To access the ACE score calculator: http://healthteamworks-media.precis5.com/ace-score-calculator
Resources for Adolescent Depression Screening and Assessment
Recommended screening tools:
1. Guidelines for Adolescent Depression in Primary Care (GLAD-PC)
http://www.thereachinstitute.org/files/documents/GLAD-PCToolkit.pdf
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Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
2. Teen Screen National Center for Mental Health Checkups
For information about the Center: http://www.teenscreen.org
For screening tools and a pocket guide with information on reimbursement and tips for making mental
health referrals: http://www.teenscreen.org/programs/primary-care
SECTION 2: Demographic and Psychosocial Considerations in Depression Care
Psychosocial stressors
• Serious adverse events – especially involving loss of a major relationship or role may trigger a major
depressive disorder (particularly true for initial episodes of depression).
• Lower socioeconomic status, living alone, unemployment, urbanization, and violent trauma may increase the
risk of major depression.
Gender
• Depression disproportionately affects women.
»» Consider the role of hormonal fluctuations in depressive symptoms in premenopausal women.
»» Consider the potential for oral contraceptive interactions with antidepressants.
»» The perimenopausal transition is a high risk period for new onset major depressive disorder.
»» Consider SSRI or SSNI to decrease somatic symptoms in perimenopausal women.
• Gender-specific antidepressant risks:
»» Priapism in men treated with trazodone
»» Anticholinergic side effects in benign prostatic hypertrophy
»» Specific effects on libido in both genders
»» Ejaculatory dysfunction associated with antidepressants
»» TCA dosage may need to be higher in women who take oral contraceptives
Bereavement
Bereavement can trigger major depression but normal grief should not be confused with depression.
• Acute grief usually resolves after a period of about 6 months.
• Complicated grief may warrant treatment with psychotherapy and/or medication.
Comorbid medical considerations
• Consider medical and medication causes of depressive symptoms.
• Treated or untreated hypertension may affect the choice of antidepressant.
• Depression increases the risk of cardiovascular disease.
• Patients with depression have a higher mortality rate after myocardial infarction.
• The risk of depression increases in the weeks and months following a stroke.
• Major depressive disorder occurs in 40-50% of patients with Parkinson’s disease.
• Major depressive disorder increases the risk of unprovoked seizures in patients with epilepsy.
• Major depressive disorder may be more common in patients with obesity (especially women). Consider the
potential for weight gain with certain antidepressants. Address how depressive symptoms affect efforts to
page 5
Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
follow a healthy diet and exercise plan.
• Depression may lead to poor treatment plan adherence in patients with diabetes.
• Sleep apnea may contribute to depressive symptoms, especially in patients who are obese, report excessive
daytime sleepiness, or who have treatment-resistant depression.
• Rates of depression are increased in patients with HIV infection.
• Pain syndromes frequently co-occur with depression; more than half of depressed individuals report some
type of pain.
• Depression commonly co-occurs with dementia; mood symptoms may precede cognitive symptoms.
• Depression is associated with worse functional outcomes in hip fracture recovery.
Older Age
• Older adults may report more vegetative signs and cognitive disturbance and less subjective dysphoria.
• Older adults may be more sensitive to antidepressant medication side effects.
• Generally start with a lower dose of antidepressant medication.
• Consider renal and hepatic function when prescribing antidepressant medications.
• Suicide risk is higher in older adults with major depression. Elderly white men have the highest rates of completed
suicides.
Pregnancy/Postpartum
During the pregnancy and postpartum periods 10-15% of women will experience a major depressive disorder.
• 50% of pregnancies in the U.S. are unplanned.
• Untreated postpartum depression places both the mother and infant at risk and is associated with significant
long-term effects on child development and behavior.
• Planning depression treatment during the perinatal period requires an individualized risk/benefit discussion.
• Depression focused psychotherapy such as Interpersonal Therapy (IPT) or Cognitive Behavioral Therapy (CBT)
is recommended for treatment of depression during pregnancy; however medication should not be avoided if
symptoms are intolerable.
• The American Academy of Pediatrics’ (AAP’s) Committee on the Psychosocial Aspects of Child and Family
Development recommends that pediatric providers should integrate screening for postpartum depression
into well-child visits.
• The MedEd Postpartum Depression (PPD) website offers information on all aspects of perinatal depression
care, including patient/family education materials: http://www.mededppd.org/default2.asp
• Medication choices for pregnancy/postpartum: http://healthteamworks-media.precis5.com/depressionpregnancy-med-chart
Cultural considerations
• Consider language barriers and the importance of accurate, sensitive interpreter services.
• Culture may influence expression of depression symptoms – particularly somatic and psychomotor symptoms.
• In some cultures depression symptoms may be more likely to be attributed to physical illnesses.
• Ask the patient, “How do you understand what you are experiencing?”
• There is greater stigma associated with a depression diagnosis and with receiving services from a psychiatrist
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Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
and/or mental health professional in some cultures.
Additional information on treatment considerations and recommendations: American Psychiatric Association
(APA) Practice Guideline for the Treatment of Patients With Major Depressive Disorder (available on the
HealthTeamWorks website: http://healthteamworks-media.precis5.com/apa-depression-guideline-2010)
SECTION 3: Prepare your practice for effective depression care
Primary care and mental health are inseparable. Recognizing depression or other mental health conditions
must begin with symptom identification and diagnosis. Screening is one important way to identify possible
depression; however, screening alone does not lead to positive clinical outcomes. The United States Preventive
Services Task Force (USPSTF) recommends screening for depression in primary care when there are staff assisted
mechanisms in place for accurate diagnosis, treatment and follow-up (B Grade recommendation).
Implement staff assisted mechanisms for diagnosis, treatment and follow-up:
1. Assemble a practice team.
Include one or more clinicians and practice support staff.
2. Develop an operational plan.
• Determine who will receive screening: All patients? All new patients? All patients in for a health
maintenance visit? Select populations? Only when depression suspected?
• Determine how to administer and document the PHQ-2/9: Self-administered on a written form? Orally
administered? Using an electronic tool or EHR?
• Determine where to administer the PHQ-2/9: Waiting room? Exam room?
• Determine who will help coordinate depression care and how that will happen: See next section for more
information
3. Design a workflow for depression diagnosis, treatment and follow-up.
Assign specific responsibilities to different members of the practice team, such as:
• Administer screening and assessment questionnaires to patients, including scoring the PHQ-9 and
entering the information into an EHR.
• Compile patient education resources.
• Maintain adequate supplies of PHQ- 2/9 forms, depression tracking logs, and patient education materials.
• Maintain accurate information about options for referral to specialists, mental health services and
community support services.
• Compile information about health plan depression care coverage.
• Provide education about depression, healthy lifestyle and depression treatment to patients and family
members.
• Assist with scheduling and communication about appointments with the primary care clinician,
psychiatrist, and/or behavioral health providers.
• Carry out structured protocols to monitor depressive symptoms (with the PHQ-9), adherence to treatment
and referrals, and medication side effects. This may be done by telephone in some cases. Establish a clear
process for documentation and communication with the providers.
• Consider using a registry or EHR registry functionality to track patients who have a diagnosis of depression.
page 7
Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
4. Establish relationships with mental health providers.
Establish relationships with mental health providers in your medical neighborhood to promote
collaboration and communication. Suggestions:
• Invite mental health providers to visit the primary care practice to introduce themselves and their specific
expertise.
• Identify referral options for specific patient demographics, such as older adults, postpartum patients, or
patients with specific language and cultural needs.
• Establish referral and communication protocols that address confidentiality, sharing of information, and
bidirectional communication. Note that mental health providers will need to address state and federal
confidentiality and privacy requirements.
Sample workflow coming soon (check HealthTeamWorks website).
SECTION 4: Mental health services and benefits information
Assess benefits information:
Health plans often specify “in network” mental health providers and parameters of the services that will be
covered (such as number of visits, emergency care, and inpatient services).
• Compile and maintain a list of available and most accessible mental/behavioral health therapists and
psychiatrists in your region.
• Include information about language, insurance options, and accessibility for patients with disabilities, and
providers that work with adolescents.
Resources:
• To identify the Community Mental Health Center in a catchment area and identify resources for behavioral
health and psychiatric services: go to the Colorado Behavioral Healthcare Council’s website: www.cbhc.org.
Click on “About Us” and drop down to “Community Mental Health Centers List”. An individual who has
private health insurance has the option of pursuing treatment with anyone credentialed with that insurance
company. Patients should contact their insurance company to identify a provider in their geographical area
(this will frequently include the local mental health centers).
• An individual who has Behavioral Health Medicaid must go through the organization that manages
Medicaid (the BHO) for their catchment area. That information is available at: www.cbhc.org. Click “About Us”.
• An individual who is uninsured must go to community agencies that accept uninsured patients. A list of
these resources is frequently available through the mental health agency in your catchment area.
• Additional resources may be accessed through the community hospitals in your area.
page 8
Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
SECTION 5: Helping individuals change behaviors
The way we interact with individuals about behavior change has a significant impact on whether each person
will actually be motivated to take steps that will improve their health and well being. Empathy is at the core
of effective conversations about behavior change. A motivational interviewing approach collaborates with an
individual to help them connect to their own intrinsic motivation and best reasons to change.
Ambivalence about change is completely normal. And change is not a linear process, but most often a set of
steps and setbacks before actual change is accomplished. In conversations about change, it is important to “roll”
with any resistance that comes up. The idea is to let the patient argue for change, not you! First, the provider
demonstrates genuine curiosity about an individual’s values, priorities, strengths, fears, and past successes and
challenges. Then, the provider helps the person develop goals and a plan that is congruent with their readiness,
abilities, assets, resources and priorities.
Specific techniques and examples:
Ask permission to give feedback and advice.
Examples:
»» “Would it be alright if I gave you some feedback/education about how alcohol could be related to the
depression?”
»» “Could we talk about diet, exercise and sleep as part of your treatment plan for depression?”
Open-ended questions.
Examples:
»» “What do you already know about depression?”
»» “What concerns do you have about the treatment options we’ve discussed?”
Affirmations (of core values and strengths).
Examples:
»» “Your health is very important to you.”
»» “You really care about being responsible and available to your family.”
Reflections (of verbal and nonverbal statements about health, behaviors, and feelings).
Examples:
»» “You feel worried about what your family will think about a diagnosis of depression.”
»» “You feel that taking a medication for depression is a sign of weakness.”
»» “It just feels overwhelming to have to do so many things to take care of your health.”
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Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
Ruler questions
Examples:
»» “On a scale from 0-10, how important is it to you to begin to get some exercise every day as a way to help
treat the depression?”
»» Followed by: “So, why a 4 and not a lower number?”
This is to get the individual talking about their desire, ability, reasons, or need to change.
»» “On a scale from 0-10, how confident do you feel that you will be able to take the next steps and begin to
get some exercise every day as a way to help manage the depression?”
»» Followed by: “What would help you to feel more confident about taking the next step and starting to
exercise?”
This is in order to identify concrete ways to help the individual set goals and make a plan.
SECTION 6: Brief supportive counseling in primary care
Brief supportive counseling interactions, lasting only a few minutes, can be carried out by different members
of a practice team (including lay health workers). In the interaction the practitioner explores the context and
stressors related to an individual’s current problem(s), the physical and emotional effects, and then helps the
individual solve problems and adopt healthy self-care practices.
Problem Focused Counseling Guideline
Define the problem and/or its potential to be improved.
Identify associated beliefs and concerns about:
• self
• the situation
• Problems and/or concerns appear to be realistic.
• Problems have potential to be improved.
Problem Solving Strategies:
• Establish a realistic goal
• Identify and evaluate possible simple small steps
to attaining goal
• Explore barriers to implementing these steps
• Discuss ways to overcome possible barriers
• Select a plan and implement it
• Review progress and celebrate success no matter
how small
Beliefs and/or concerns may be modifiable &
maladaptive (e.g. “I am at fault or a failure”)
General Coping Strategies:
• Provide reflection (“I can see this is upsetting
you”), empathy (“I can appreciate how difficult
this must be for you”), legitimation (“It is normal
to feel this way”)
• Encourage patients to focus on and participate
in activities that are: pleasurable, relaxing, and/or
rewarding (e.g. hobbies, exercise, taking a bath,
vacation, etc.)
• Encourage patients to spend more time with
family and friends who can support them
• Discuss importance of adequate sleep and good
nutrition
Cognitive Strategies:
• Discuss why the patient feels this way
• Evaluate the evidence for the negative thought
• Identify alternative explanations that are realistic
and believable
• Determine the type of information the patient
needs to modify the thought
• Encourage patient to survey others regarding the
validity of their thought or to evaluate the costs
and benefits of maintaining the thought
• Encourage patient to identify and focus on their
more positive qualities
• Monitor changes in beliefs and impact on moods
Reference: Brody DS, Thompson TL, Larson DB, et al Strategies for Counseling Depressed Patients by Primary Care Physicians. J or General In Med 1994; 9:569-575.
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Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
SECTION 7: Co-occurring Psychiatric and Dependence Disorders
Tobacco dependence
• Patients with a history of major depressive disorder may be at risk for recurrence when they attempt tobacco
cessation.
• Use the PHQ-9 to monitor depressive symptoms throughout the process of tobacco cessation.
• Develop a tobacco cessation plan that also addresses depressive symptoms.
• Buproprion and nortriptyline increase tobacco cessation by about two-fold.
• Provide education about the temporary risk of depression relapse, the importance of tobacco cessation, and
available support services and treatments.
• Multiple methods are more effective than single methods for tobacco cessation (e.g. QuitLine services +
medication).
Substance abuse
• Frequently co-occurs with depression
• It may be difficult to distinguish substance-induced depressive disorder from major depressive disorder.
• Use the HealthTeamWorks Screening Brief Intervention Referral to Treatment (SBIRT) Guideline: http://
www.healthteamworks.org/guidelines/sbirt.html to assess the use of alcohol, illicit and prescription drugs.
• Current recommendation: Treat both disorders simultaneously and actively (SAMHSA).
• These patients are more likely to require inpatient treatment.
• There is a greater risk of suicide in these patients.
• These patients are less likely to adhere to treatment.
• Substance abuse treatment options in CO: www.LinkingCare.org (CO Division of Behavioral Health web portal)
Anxiety disorders
• The most commonly co-occurring disorders in patients with major depression (may co-occur in ~60% of
patients with depression)
• Treatment:
»» Both anxiety and depression may respond to antidepressant medication.
»» TCAs and SSRIs may initially worsen rather than alleviate anxiety. Introduce medication at a low dose and
advise the patient about possible initial increased anxiety symptoms.
»» Adjunctive medication (e.g., benzodiazepines) may be necessary.
»» Psychotherapies- in particular CBT and IPT may be useful (see psychotherapy section for more information).
Dysthymic disorder
• A chronic mood disorder with symptoms that fall below the threshold for major depressive disorder
• May co-occur with major depression (“double depression”)
• Treatment: Similar as for major depression; may respond best to medication + therapy
page 11
Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
Dementia
• All patients with dementia should be screened for depression (if cognitive status allows).
• Carefully monitor pharmacotherapy in patients with dementia.
• Antidepressants are likely to be efficacious even though they are unlikely to improve cognition.
• Antidepressants with the least anticholinergic effects are recommended.
• ECT may be helpful for some patients with co-occurring depression and dementia.
• For current criteria and guidelines for Alzheimer’s Disease diagnosis: http://www.alzheimersanddementia.org/
content/ncg
Eating disorders
• Eating disorders are common in patients with major depression.
• SSRIs are the best studied medications for the treatment of eating disorders. Fluoxetine has the most evidence
for the treatment of bulimia nervosa.
• Antidepressants may be less effective in patients who are severely underweight or malnourished.
For additional information on treatment considerations and recommendations see the American Psychiatric
Association (APA) Practice Guideline for the Treatment of Patients With Major Depressive Disorder available
on the HealthTeamWorks website: http://healthteamworks-media.precis5.com/apa-depression-guideline-2010.
SECTION 8: Complementary and Alternative Medicine (CAM)
“CAM is a group of diverse medical and health care systems, practices, and products that are not presently
considered to be part of conventional medicine.” (NIH National Center for Complementary and Alternative
Medicine).
Complementary therapies refer to those that are not considered mainstream but are consistent with Western
biomedical concepts.
Alternative therapies are more philosophically separate from traditional Western medical practice.
Integrative medicine incorporates standard Western medicine and CAM to use all therapies that are considered
appropriate for an individual’s needs.
• Currently at least 40% of adult Americans use at least one CAM treatment annually and major depressive
disorder was the most common diagnosis associated with CAM use in one study.
• Clinicians should routinely ask patients about CAM treatments they may be using to treat depressive
symptoms since patients may not disclose use of nonconventional treatments.
• Consider that in some patients use of CAM modalities that may not be efficacious may delay initiation of other
efficacious depression treatment(s).
A resource for checking the quality of supplements is the Natural Medicines Comprehensive Database:
http://naturaldatabase.com. Use of this database requires a subscription.
The PDR publishes a guide on herbs and supplements.
Direct patients to select supplements with the GMP and/or USP stamps to insure quality.
page 12
Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
5-HTP and tryptophan
Evidence is lacking on the effectiveness of tryptophan for depression. It was banned by the FDA in 1989 due
to an outbreak of Eosinophilia-Myalgia Syndrome (EMS). Some studies suggest that 5-HTP may be an effective
treatment for depression (perhaps comparable to prescription antidepressants); other studies have not found
a benefit. It can have serious adverse effects just like prescription antidepressants. There is also concern
regarding possible contaminants. Potential dangers may outweigh any possible benefits.
Acupuncture
Acupuncture is part of traditional Chinese medicine. There is significant variation in acupuncture techniques.
• Evidence for the efficacy of acupuncture as a primary treatment for depression is inconclusive.
• This is a challenging modality to study adequately in randomized control trials.
Exercise
Exercise is well established for its contribution to overall health.
• Aerobic and nonaerobic exercise have positive effects on mood in men and women across a wide age range.
• Exercise may help prevent depressive symptoms during the antepartum or postpartum period.
• Exercise may also help prevent relapse and recurrence of depression.
Folate
Folate has been studied as a predictor of antidepressant medication response and as an adjunctive treatment.
• Higher folate levels at treatment baseline appear to be associated with better response to antidepressants.
• Folate is a low-risk intervention with general health benefits, including protection against neural tube defects
in early pregnancy.
• There is no evidence about the efficacy of folate as a monotherapy for antepartum or postpartum depression,
or for depression during the menopausal transition.
Light therapy
Bright light therapy is an evidence-based, effective, and well tolerated treatment for seasonal affective disorder.
• The mechanism is unclear but appears to involve the serotonergic neurotransmitter system.
• In general, this may be a reasonable treatment option for nonseasonal depression.
• Light therapy may hasten the response to antidepressant medication.
• Greater intensity of light is associated with efficacy.
• Monitor for mania and hypomania during initiation of light therapy.
• More research is needed in order to determine the efficacy of this method for nonseasonal depressive
conditions specific to women (PMS, antepartum and postpartum depression, postmenopausal transition
page 13
Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
depressive symptoms).
• The preferred apparatus is a commercially produced fluorescent box with a light intensity of 10,000 lux.
»» To use: sit in front of the downward tilted box situated 12-14 inches from the eyes.
»» The starting dose is 10,000 lux for 30 minutes in the morning.
Mindfulness and other mind-body therapies
• Mindfulness-based cognitive therapy may decrease symptoms of depression and anxiety and shows promise
for preventing depression relapse and recurrence.
• Other mind-body therapies that show promise in the treatment or depression and anxiety and may play
promote overall health include meditation, Qigong, Tai Chi, yoga, and biofeedback and neurofeedback.
Omega-3 fatty acids
Generally recommended as an adjunctive therapy since the health benefits, especially for cardiovascular health,
are established, and individuals with psychiatric disorders may be at greater risk for obesity and metabolic
problems than the general population.
• Adjunctive EPA, or the combination of EPA and DHA (what is found in most commercial brands) appears most
useful for depressive disorders.
• Dosages from 1-9 grams have been studied and the evidence supports lower doses.
• Omega-3 fatty acid supplementation is a reasonable augmentation strategy in depression treatment.
• Evidence is sparse concerning Omega-3 fatty acids for PMS, antepartum and postpartum depression, or
depressive symptoms during the menopausal transition.
S-adenosyl methionine (SAMe)
SAMe is a naturally occurring molecule. Cerebrospinal fluid levels of SAMe are lower in individuals with severe
major depressive disorder compared with control subjects.
• Some data support the efficacy and tolerability of SAMe in patients with major depressive disorder.
• More research is needed to determine the comparative efficacy of SAMe to standard antidepressants.
• Available preparations are not regulated by the FDA and formulations may vary widely.
• SAMe may be effective for treatment of depressive symptoms during the menopausal transition.
• Safety and efficacy of SAMe for antepartum depression or in women who are breastfeeding has not been
adequately studied.
St. John’s Wort
St. John’s Wort is a plant that is widely used to treat depressive symptoms.
• There is conflicting evidence for the effectiveness of St. John’s Wort.
»» The available evidence suggests that it may be superior to placebo in major depression, similarly effective as
standard antidepressants, and have fewer side effects than standard antidepressants.
page 14
Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
»» Overall, studies show greater support for benefits in mild-moderate depressive disorder and less consistent
findings in patients with more severe symptoms.
• Drug-drug interactions are an important consideration. The efficacy of some medications may be decreased
by St. John’s Wort, including antiretroviral medications, immunosuppressants, antineoplastic agents,
anticoagulants, oral contraceptives, and hormone replacement therapy.
• St John’s Wort is excreted in breastmilk at levels comparable with other antidepressants.
SECTION 9: Evidence-based mental health therapies for depression
Interpersonal
psychotherapy
(IPT)
Problem-solving
therapy (PST)
Focus
Resolving everyday
How relationships
problems that
and interpersonal
may contribute
events affect
to depression.
the onset or
Brief, structured
maintenance of
treatment.
depression. Usually
Combines elements
short term.
of CBT and IPT.
How thoughts and
beliefs influence
depression and a
person’s behaviors.
Usually short term.
Process
Cognitive/
behavioral
therapies (CBT)
Recognize and
Recognize and
change distorted
change patterns of
social functioning
beliefs and
dysfunctional
that cause
problems. Explore
thinking to be
more adaptive and
issues that may
healthy; change
contribute to
behaviors and
depression: grief,
solve problems that
role transitions,
interpersonal
may contribute to
depression.
deficits or conflicts.
Improve ability
of an individual
to understand
and cope with
stressful life
experiences, and
resolve problems
constructively.
Couples/Family
therapy
Psychodynamic
therapy
How relationships
On the etiology
with family/
of psychological
significant others
vulnerability
can be a resource
that may lead
to help resolve
to depression
depression.
stemming from
Family/significant
development and
others included in conflict throughout
therapy.
the life cycle.
Address conflicts
Identify difficulties
and conflicts that
related to
may contribute
guilt, shame,
interpersonal
to depression
and find ways to
relationships,
management
resolve w/ effective
communication.
of anxiety,
Improve
and repressed
or socially
relationships to
support depression
unacceptable
treatment.
impulses.
SECTION 10: Recommended patient education books and online resources
Important components of depression care:
• To help patients and their families understand and accept a diagnosis of depression.
• To activate patients to seek help, adhere to treatment recommendations, and practice healthy behaviors that
can promote recovery.
page 15
Depression in Adults: Diagnosis & Treatment
Guideline Supplement
References and supporting documents used to develop the guideline and supplement are available at:
http://www.healthteamworks.org/guidelines/depression.html.
Web sites:
1. The MacArthur Initiative Depression Tool Kit: http://www.depression-primarycare.org
2. Medicine Plus Depression Tutorial:
http://www.nlm.nih.gov/medlineplus/tutorials/depression/htm/index.htm
3. Depression Awareness Recognition and Treatment Program of the National Institute of Mental Health:
http://www.nimh.nih.gov/publicat/index.cfm
4. National Foundation for Depressive Illness: http://www.depression.org
5. Mental Health America: http://www.mentalhealthamerica.net/
6. E-Couch: http://ecouch.anu.edu.au/welcome
7. MoodGym: Free online self help program; teaches cognitive behavior therapy skills:
http://www.moodgym.anu.edu.au/welcome
8. National Mental Health Alliance: http://www.nami.org
Self-help manuals and books:
Cognitive and behavior oriented self-help books have been shown to significantly improve symptoms of
depression for up to 2 years. Recommended resources:
1. Burns DD: Feeling Good The New Mood Therapy. Avon Books 1999.
Updated version; teaches a cognitive therapy approach to combating depression. Includes techniques to
identify and combat faulty thinking, self assessment techniques, self help forms and charts and a section on
medication.
2. Hayes SC: Get Out of Your Mind and Into Your Life: The New Acceptance and Commitment Therapy.
New Harbinger 2005.
A five-step plan for coping with painful emotions such as anxiety and depression. Patients learn to engage
with painful thoughts and feelings through step-by-step acceptance and mindfulness.
3. McKay M, Fanning P and David M: Thoughts and Feelings: Taking Control of Your Moods and Your Life:
A Workbook of Cognitive Behavioral Techniques. New Harbinger 2007.
Offers a simple and easy to understand discussion on how to use the principles of cognitive behavioral
therapies to control anxiety and depression and enhance self-esteem.
4. Lewinsohn P: Control Your Depression (revised). Simon and Schuster 2010.
A classic text that helps patients identify specific areas related to their depression. Provides instruction on
self control strategies, relaxation techniques, social skills training, and modification of self-defeating thinking
patterns.
5. Katon W, Ludman E, Simon G: The Depression Helpbook. Bull Publishing Co. 2008.
Explains what causes depression, how to recognize it, and how to make decisions about treatment.
Integrates pharmacologic and psychotherapeutic approaches; emphasizes self-care strategies to help
develop confidence in one’s ability to manage depression.
page 16
Depression in Adults: Diagnosis & Treatment Guideline
~14% of adults have a major depressive episode in their lifetime
~30% of adults with major depression do not receive treatment
This guideline is intended for ages ≥18 years. For adolescents and pre-adolescents, use GLAD PC or Teen Screen Mental Health Check-ups.
Prepare your practice: put systems in place for accurate diagnosis, treatment, and follow-up.
Tip 1: Implement staff assisted patient self-management and care coordination (possible by phone).
Tip 2: Compile info on psychiatry and mental health consultation and referral options.
1. Screening and Assessment
1. Screening and Assessment
Consider Depression: High Risk Conditions and Cues
• Chronic conditions (CVD, Diabetes, cognitive impairment)
• Chronic pain
• Geriatric patient
Screening:
Screen if systems are in place for adequate diagnosis/
treatment/follow-up/referral. Use PHQ-2*. “In the past 2 weeks…
1. Have you had little interest or pleasure in doing
things?
2. Have you felt down, depressed or hopeless?”
If “yes” on either question, complete full PHQ-9*.
2. Diagnosis (first episode or recurrence?)
DSM IV Criteria
Symptom
1. Depressed mood
2. Marked Diminished Interest/Pleasure
3. Significant wt loss/gain, appetite decrease/increase
4. Insomnia/hypersomnia
5. Psychomotor Agitation/Retardation
6. Fatigue/loss of energy
7. Feelings of worthlessness or inappropriate guilt
8. Diminished concentration or indecisiveness
9. Suicidal ideation: thoughts, plans, means, intent
10. Hopelessness
Tip 3: Identify resources to address treatment barriers.
Tip 4: Monitor symptoms with PHQ-9*.
• Multiple somatic complaints
• Postpartum
• Tobacco Use
• ETOH/Substance misuse/abuse
• Chronic anxiety
• History of Abuse/Trauma/PTSD
• Combat veteran
• Persistent anger/irritability
• Recent loss
Further Assessment:
1. Recent life events (Why now?)
2. History of depression/bipolar disorder or alcohol/substance misuse
3. Patient’s perception of problem:
»» Beliefs and knowledge about depression
»» Cultural considerations (language, stigma, influence on symptom presentation)
4. Consider medical and medication causes of depression
5. Family history: depression/bipolar disorder
6. Suicide risk (thoughts, plans, means, previous attempts, recent exposure). “Are you thinking of harming or
killing yourself?”*
7. Assess risk of harming others
8. Screen for co-morbid psychiatric disorders: bipolar, anxiety, PTSD, panic disorder, tobacco†, substance misuse†
9. Complementary/Alternative Medicine or other treatments currently used*
2. Diagnosis (first episode or recurrence?)
Major Depression
5 total for 2 wks
duration:
must include
symptom #1 or 2
a
a
a
a
a
a
a
a
a
Dysthymia
3 total for ≥2 yrs.:
must include
symptom #1
Severity Rating (Based on initial PHQ-9* score):
PHQ-9
Score
5-9
a
10-14
a
a
15-19
a
a
a
≥20
Provisional Diagnosis
Minimal Symptoms
Minor Depression
Dysthymia
Major Depression, mild
Major Depression,
moderately severe
Major Depression,
severe
Treatment
Recommendations
Support, educate to call if
worse; return in 1 month
Evidence-based
psychotherapy equally
effective as anti-depressant
Evidence-based
psychotherapy and/or antidepressant
Anti-depressant and
psychotherapy (esp. if not
improved on monotherapy)
a
Plan Treatment (see page 2 for treatment chart)
3. Plan Treatment (see page 2 for treatment 3.
chart)
Shared Decision Making:
• Tailor treatment to individual patient
• Provide education on diagnosis
• Review treatment options (based on PHQ-9 score)
• Discuss treatment barriers: family/work
responsibilities, insurance, transportation
• Negotiate treatment plan
• Set timeline: response, side effects and treatment duration
• Educate on importance of adherence
• Develop safety plan for suicidal ideation
Promote Health Behaviors:
• Exercise
• Social support
• Faith/spiritual support
• Healthy sleep pattern
• Healthy diet
• Alcohol only in moderation†
• Cessation of tobacco and illicit drug use†
• Engagement in positive activities
• Stress management
• Educational books and online resources
Additional Considerations:
• Current or planned pregnancy: psychotherapy
preferred if symptoms tolerable*
• Start with lower dose for anxiety or elderly*
• Cultural factors that influence treatment choice*
• SNRI or tricyclic for chronic pain
• Level of functioning/activities of daily living
• Discuss safety with the patient*
• Need for emergency services
• Psychiatry referral, including ECT evaluation
• Complementary/Alternative Medicine*
Consider Referral or Consult:
• Suicidal patient • Bipolar disorder • Co-occurring substance abuse • Psychotic features • Multiple medications
*See supplement for additional information.
†Go to www.healthteamworks.org for guidelines on Tobacco & Alcohol/Substance Use.
This guideline is designed to assist the primary care provider in the diagnosis and treatment of depression. It is not intended to replace a clinician’s judgment or establish a
protocol for all patients. The Depression Guideline supplement, references, and additional copies of the guideline are available at www.healthteamworks.org
or call (303) 446-7200. This guideline was supported through funds from The Colorado Health Foundation. Approved 1/3/2011.
page 1 of 2
3. Plan Treatment Continued: Treatments for Depression
Evidence-Based Psychotherapies*
• Cognitive/behavioral therapy (CBT)
• Interpersonal psychotherapy (IPT)
• Problem-solving therapy (PST)
• Psychodynamic therapy
• Couples/Family therapy
If receiving therapy alone:
• Onset of effectiveness is more gradual
• Discuss and share PHQ-9* with therapist
Considerations for Medication Selection
• Cost
• Formulary
• Responsiveness to prior treatment
• Responsiveness in a first degree relative
• Complementary/Alternative Medicine*
Medication Chart
Adverse Side Effects and Precautions‡
Paroxetine (Paxil CR)
12.5-25 mg QAM
25-62.5 mg
Sertraline (Zoloft)
25-50 mg QAM
50-200 mg
Venlafaxine (Effexor)
25 mg BID-TID
Venlafaxine XR (Effexor-XR)
Duloxetine (Cymbalta)
Desvenlafaxine (Pristiq)
Bupropion (Wellbutrin)
37.5 mg QD
20 mg BID or 30 mg QD
50 mg QD
100 mg BID-TID
Bupropion (Wellbutrin SR)
100 mg QAM to 100 mg BID 150-200 mg BID
Bupropion (Wellbutrin XL)
150 mg
Mirtazapine (Remeron or Remeron Sol-Tab)
Trazodone Long-Acting (Oleptro)
Amitriptyline (Elavil)
150-375 mg
a
150-225 mg
60 mg
50 mg
300-450 mg
a
+++
+
0
++
++
+++
+++
+++
+
+
0
0
++
+
+++
++
+++
+++
+
+
0
0
+
+++
0
++
+++
+
0
+++
0
+++
+++
+
0
+
0
++
++
0
0
X
0
0
0
0
++
++
0
0
X
a
+
+
0
0
++
++
++
+
+
0
0
0
0
0
0
0
X
a
0
0
++
0
0
0
X
300-450 mg
a
0
0
++
0
0
0
X
X
15 mg QHS
150 mg QHS
25-75 mg QHS
15-45 mg
150-375 mg
100-300 mg
a
+
+
+++
++
+++
+++
0
0
+++
+
0
0
+
+
+
+++
+++
+++
X
X
X
X
+
++
a
Clomipramine (Anafranil)
25-75 mg QHS
100-250 mg
+++
+
+
++
++
+++
X
X
++
a
Desipramine (Norpramin)
25-75 mg QHS
100-300 mg
a
+
0
++
+
+
+++
X
X
++
a
Doxepin (Adapin, Sinequan)
25-75 mg QHS
100-300 mg
a
+++
+++
0
++
++
+++
X
X
++
a
Imipramine (Tofranil)
25-75 mg QHS
100-300 mg
a
+++
++
+
+
++
+++
X
X
++
a
Nortriptyline (Aventyl, Pamelor)
25-50 mg QHS
30-150 mg
a
++
++
+
+
++
++
X
++
Drug
Daily Starting Dosage
Usual Daily
Adult Dosage
a
a
a
a
a
a
a
a
Cardiac Arrhythmia
Orthostatic Hypotension
0
Weight Gain
0
a
Sexual Dysfunction
a
Activation
0
0
+
0
0
++
Category
SSRIs
SNRIs
Other Agents
0
0
0
0
0
High Potential
for Lethal
Overdose
a
Liver Disease
a
Precautions
Eating Disorders
20-40 mg
10-20 mg
20-80 mg
90 mg
20-50 mg
Sedation
On the $4 plan?
10-20 mg QAM
10 mg QAM
10-20 mg QAM
90 Qwk
10-20 mg QAM
Side Effects
Anticholinergic
Generic?
Citalopram (Celexa)
Escitalopram (Lexapro)
Fluoxetine (Prozac)
Fluoxetime (Prozac weekly)
Paroxetine (Paxil)
0 = very low, none
X = generally contraindicated
Withdrawal Syndrome Risk
Relative
Cost
Pregnancy: Requires individualized risk/benefit discussion.*
Tricyclics
+++ = strong
++ = moderate
+ = mild
Seizure Disorder
FDA Black Box Warning: In short-term placebo controlled studies antidepressants increased
the risk compared to placebo of suicidal thinking and suicidality in children, adolescents, and
young adults; but not in adults beyond age 24; and there was a reduction in risk in adults age
>65. Monitor all patients closely for clinical worsening, suicidality, or unusual changes in
behavior.
++
X
X
+++
X
+++
X
X
++
+
+
X
+
X
+
++
a
‡References: Applied Therapeutics: the clinical use of drugs. Edited by Mary Anne Koda-Kimble, et al. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, c2009. 9th edition. International consensus statement on major depressive disorder. Nutt DJ, et al. J Clin
Psychiatry. 2010; 71 Suppl E1:308. Drug facts and comparisons. St. Louis: Facts and Comparisons, c1981-2010. Circulation. 2009 September 22; 120(12): 1123-1132. Expert opinion.
4. Monitor and Adjust Treatment. Monitor Side Effects. Goal of treatment is complete remission.
First follow-up contact at 1-2 weeks, then every 4-8 weeks (consider telephone contact in some cases). Perform ongoing suicide risk assessment; risk may increase during
early treatment phase. If starting dose was low, consider up-titration at initial check-in.
Acute Phase (months 1-4)
Response
PHQ-9* Score after 4-6 weeks
Treatment Plan
Responsive
Drop ≥5 points from baseline
No treatment change needed. Follow-up again after an additional 4 weeks.
Partially responsive
Drop 2-4 points from baseline
Often warrants increase in dose. Possibly no change needed.
Drop 1 point or no change or
increase
• Consider starting anti-depressant if receiving therapy
alone
• Increase dose
• Switch meds
• Augmentation (Lithium, thyroid, stimulant, 2nd gen
anti-psychotic, 2nd anti-depressant)
Non-responsive
• Review psychological counseling options and
preferences
• Informal or formal psychiatric consulation
(ECT an option in some cases)
Continuation Phase (months 4-9)
Maintenance Phase for Recurrent Depression (month
9 and on)
Tapering Anti-Depressant Medication
• Begins after symptom resolution
• Continue medications full strength • Contact every 2-3 months (telephone appropriate
in some cases)
• Monitor for signs of relapse
• Generally, use same anti-depressant dose as in
Acute Phase
• For patient with history of 3+ episodes of Major
Depression or chronic Major Depression
• Also consider for patient w/ additional risk factors for
recurrence (family history, early age onset, ongoing
psychological stressors, co-occurring disorders)
• May need to maintain for one to several years
• Use PHQ-9* for ongoing monitoring
•
•
•
•
Goal: Prevent Relapse
*See supplement for additional information
Taper over several weeks
Educate about side effects and relapse
Flu-like symptoms common
With SSRI and SNRI may also experience
anxiety/agitation, sweats, paresthesias
• Diphenhydramine may help with
anticholinergic withdrawal symptoms
Supplemental Guidance on Marijuana
Page 1 of 2
Information to guide work with adolescents and adults.
Why Screen for Marijuana
Recommendations for Screening and Brief Intervention
• Marijuana is the third most commonly used substance after tobacco and
alcohol in the U.S., Australia and Europe.
• Marijuana use is associated with health and mental health problems.
• Adolescents are particularly at risk for developing problems related to use.
• Marijuana users who begin during adolescence have a 1 in 6 chance of
developing dependence.
• Current research does not provide safe limits of use; there is insufficient
research on potential medical benefits of marijuana.
• Screen adults and adolescents aged 12 and older.
• Recommended screening question:
“In the past year, how many times have you used marijuana?”
Positive score = > 1 time
• Assess for possible cannabis use disorder
• Offer a personalized brief intervention for marijuana use.
In Colorado:
- 2001: medical cannabis use was permitted
- 2013: recreational cannabis (1 oz. or less) was legal to possess and consume in private residencies
for individuals ages 21 and older.
Per the Colorado constitution, medical marijuana may be recommended for:
• Cancer
• Glaucoma
• HIV or AIDS positive
OR ..
The patient has a chronic or debilitating disease or medical condition that produces one or
more of the following and which, in the physician’s professional opinion, may be alleviated
by the medical use of marijuana.
•
•
•
•
•
Cachexia
Persistent muscle spasms
Seizures
Severe nausea
Severe pain
Click here for updated CDPHE information or follow:
http://www.colorado.gov/cs/Satellite?c=Page&childpagename=CDP
HE-CHEIS%2FCBONLayout&cid=1251593017076&pagename=CBONW
rapper
Strains
1. Cannabis indica
• Larger amounts of Cannabidiol
• Known for relaxation, commonly used to relieve
inflammation, and glaucoma.
2. Cannabis sativa
• Larger amounts of Tetrahydrocannabinol (THC)
• Known to be more energizing; can reduce headaches,
pain and nausea and stimulate appetite.
• Sativa has higher tendency to induce anxiety or
paranoia
3. Cannabidiol by itself, lacks noticeable psychoactive effects
General Effects of Marijuana
• Temporarily increases heart rate and blood pressure; increases risk of cardiac
arrest and stroke.
• May interact with prescription medications (especially barbiturates, CNS
depressants, theophylline, warfarin and fluoxetine).
• Avoid marijuana if scheduled for surgery in the next two weeks (may cause
excessive sedation when combined with parioperative medications).
• Diminished motor coordination
• Distorted perception (sights, sounds, time, touch)
Pregnancy-Postpartum Key Points
Adolescent Key Points
• Problems with learning and memory
• Increased risk of psychosis
• Risk of long-term neurocognitive deficits
and reduced IQ
• Chronic use of marijuana increases the risk of:
• Impaired cognitive functioning, memory, and decision-making
• Depression and anxiety
• Weakened immune system
• Infertility
• Cannabinoid Hyperemesis Syndrome
• Chronic use of smoked marijuana increases the risk of:
• Oral cancer
• Chronic bronchitis
• Frequent upper respiratory infections
• Pneumonia
•
•
•
•
THC crosses the placenta and is a form of exposure.
THC is present in breast milk and a form of exposure.
Marijuana use may increase the risk of miscarriage.
Prenatal exposure is associated with long-term motor, mental health and neurobehavioral
problems (including problems with learning and attention).
• Prenatal or exposure while breast-feeding may cause irritability and poor sleep in the infant.
Safety Concerns
• Impaired driving. Marijuana is associated with a 2-3-fold increase in motor vehicle crashes (lower risk than alcohol).
• Second-hand smoke exposure.
• Accidental ingestion by young children and pets (edibles and smoked).
This guideline is designed to assist clinicians with Marijuana supplemental information to implement for management. It is not intended to replace a clinician’s judgment or establish a protocol for all patients.
For copies of the supplement, go to www.healthteamworks.org or call (303) 446-7200. This guideline was supported with funds from SBIRT Colorado.
FINAL January 7, 2014
Supplemental Guidance on Marijuana
Page 2 of 2
Information to guide work with adolescents and adults.
Discussion with Parents
Key factors to prevent use:
• Parental involvement and monitoring
• Engagement in school
• Healthy, strong neighborhood
attachments
Important things parents need to know:
• Use of marijuana can be especially harmful to adolescents because the brain
is still developing.
• Be nonjudgmental and offer opportunities for the young person to disclose
use.
• Communicate a “no-use” expectation.
• Share stories of drug incidents and people in recovery.
Brief Intervention Key Points
• Raise the subject (ask permission to discuss marijuana).
• Explore underlying reasons for using marijuana (stress, anxiety, depression, physical symptoms). Explore lifestyle and other
alternatives to marijuana for management of symptoms.
• Use reflective listening to try to understand a person’s beliefs about marijuana and reasons for using it.
• Offer feedback (with permission) on short and long term health effects of marijuana tailored to the person’s age, health and
life circumstances.
• Advise to cut back, or consider abstaining - especially if experiencing negative health consequences or at higher risk such as
adolescents or pregnant and breastfeeding woman.
• Negotiate and advise a plan to decrease or stop use. Focus on reducing harm to self and others.
• Offer assistance and referral if needed.
• Follow-up to monitor progress.
Suggestions For Addressing Common Myths About Marijuana
Marijuana is all natural
• Marijuana may also contain harmful contaminants. Many
natural substances are known to harm human health.
Marijuana is not addictive
• Marijuana can be addictive.
• Overall ~9% of users will become addicted; Of those who
start young ~17% will become addicted; 25-50% of daily
users will become addicted.
No one has ever died from a marijuana overdose
• In Colorado emergency room visits are increasing related to
marijuana induced delirium, cyclic vomiting and overdoses.
Potency has increased dramatically over the years. Edibles
may especially deliver very high doses. There are no reliable
controls over strength and dosing.
It’s legal. So why quit, or how could it be a problem?
• Other legal substances such as tobacco, alcohol, and
prescription narcotics cause significant harm. Marijuana is
associated with serious, long-term negative health effects.
Marijuana is safer than tobacco or alcohol
• Similar to alcohol or tobacco, chronic use of marijuana may
harm health and other areas of a person’s life. Marijuana
may especially be harmful in adolescents, and pregnant and
breastfeeding women.
Marijuana is an effective treatment for serious medical
conditions (cancer, epilepsy, diabetes, depression, etc.)
• Serious medical conditions should be managed by a
qualified health professional. Self-treatment or augmenting
conventional treatments with marijuana could cause harm.
Marijuana is safer than smoking tobacco during pregnancy
• Tobacco and marijuana can harm the developing fetus
in different ways. The effects of marijuana on fetal
development may be long-term and include problems with
learning and behavior.
Marijuana helps with stress and anxiety
• It is important to identify underlying causes of stress and
anxiety. Explore alternatives to marijuana. Heavier users of
marijuana may experience improved mental clarity and
motivation when they stop using.
Cannabis Use Disorder
Indicated by a problematic pattern of marijuana use leading to clinically significant impairment or distress manifested by at least two
of the criteria for a substance use disorder. For example: 1) recurrent use resulting in a failure to fulfill major role obligations at work,
school, or home; 2) continued use despite having persistent or recurrent social or interpersonal problems caused or exacerbated by
marijuana 3) tolerance; or 4) withdrawal.
See the HealthTeamWorks SBIRT guideline webpage for information about DSM-5 diagnostic criteria for Substance Use Disorder at
http://www.healthteamworks.org/guidelines/sbirt.html
To identify treatment and
recovery support services
in Colorado, please visit
www.LinkingCare.org
For More Information: National Institute on Drug Abuse
– For Adults: drugabuse.gov/drugs-abuse/
– For Teens: teen.drugabuse.gov/drug-facts/marijuana
For Additional
Resources, Go To:
www.healthteamworks.
org/guidelines/
sbirt.html
This guideline is designed to assist clinicians with Marijuana supplemental information to implement for management. It is not intended to replace a clinician’s judgment or establish a protocol for all patients.
For copies of the supplement, go to www.healthteamworks.org or call (303) 446-7200. This guideline was supported with funds from SBIRT Colorado.
FINAL January 7, 2014
Guideline for Alcohol and Substance Use Screening,
Brief Intervention, Referral to Treatment (SBIRT)
page 1 of 2
Why screen for alcohol and drug use?
Brief motivational conversations with patients can promote significant, lasting reduction in risky use of alcohol and other
drugs. Nearly 30% of adult Americans engage in unhealthy use of alcohol and/or other drugs, yet very few are identified or
participate in a conversation that could prevent injury, disease or more severe use disorders.*
E
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1
Brief Screening
Frequency:
»» Tobacco: Every visit.
»» Alcohol and Drugs: At least yearly; consider screening at every visit.† Consider more frequent screening for women who are pregnant or who are contemplating
pregnancy; adolescents; and those with high levels of psychosocial stressors.
Youth (ages 11-17 years)
See CRAFFT Toolkit for youth information, talking points, tools and more at http://healthteamworks-media.precis5.com/sbirt-crafft-toolkit
Adults (18+ years old)
Substance
Questions
Positive Screen
Alcohol:
Assess
frequency
and
quantity
1. How many drinks do you have per week?
1. All women or men >65 years: More than 7.
Men ≤65 years old: More than 14.
----------------------------- OR ---------------------------2. In the past 3 months.
Drugs‡
In the past year, have you used or experimented with an illegal drug
or a prescription drug for nonmedical reasons?
Yes
Tobacco
Do you currently smoke or use any form of tobacco?
Yes
---------------------------------------------------------------------------------------------2. When was the last time you had 4 or more (for men >65 years and
all women) or 5 or more (for men ≤65 years) drinks in one day?
For all patients, consider:
E
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2
Reinforce healthy
behaviors.
See
“For all patients,
consider:”
A standard drink is:
• Any alcohol use is a positive screen for patients
under 21 yrs. or pregnant women.§
• Potential for alcohol-exposed pregnancy in
women of childbearing age; assess for effective
contraception use.§
+
Negative Screen
• Alcohol/medication interactions.
• Chronic disease/alcohol precautions.
• Role of substance use in depression and other
mental health conditions.¶
• Medical marijuana use.
Positive on alcohol and/or drug brief screen: proceed to Step 2.
Tobacco use only: see page 2 for Tobacco Advise and Refer.
Further Screening
Patients with a positive brief screen should receive further screening/assessment using a validated screening tool. Scoring instructions are on each tool.
Screening tools in English and Spanish available at www.healthteamworks.org/guidelines/sbirt.html
Screening tools:
• AUDIT (adult alcohol use)
http://healthteamworks-media.precis5.com/sbirt-audit
• DAST-10© (adult drug use)
http://healthteamworks-media.precis5.com/sbirt-dast-10
• ASSIST (adult poly-substance use)
http://healthteamworks-media.precis5.com/sbirt-assist
• CRAFFT (adolescent alcohol and drug use)
http://healthteamworks-media.precis5.com/sbirt-crafft
Low risk: Provide positive reinforcement
Moderate risk: Provide brief intervention
Moderate-high risk: Provide referral to brief therapy
High risk: Refer to treatment
STEP 3
(page 2)
* “Helping Patients Who Drink Too Much: A Clinician’s Guide,” U.S. Department of Health and Human Services, National Institutes of Health, National Institute on Alcohol Abuse and
Alcoholism. Updated 2005. www.niaaa.nih.gov/guide
† See Clinical Preventive Health Recommendations for the General and Targeted Populations Guideline at: www.healthteamworks.org/guidelines/prevention.html.
‡ See Prescription Drug Misuse supplement at www.healthteamworks.org/guidelines/sbirt.html.
§ See Fetal Alcohol Spectrum Disorder (FASD) supplement, Preconception and Interconception Care Guideline, and Contraception Guideline at www.healthteamworks.org.
¶ See Depression in Adults: Diagnosis and Treatment Guideline at: www.healthteamworks.org/guidelines/depression.html.
This guideline is designed to assist clinicians with alcohol and substance use screening and management. It is not intended to replace a clinician’s judgment or establish a protocol for all patients.
For national recommendations, references and additional copies of the guideline, go to www.healthteamworks.org or call (303) 446-7200. This guideline was supported with funds from SBIRT Colorado.
Approved September 2011.
E
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3
Brief Intervention - Brief Therapy - Referral to Treatment
For more information, demonstration videos, an online training module and the CRAFFT Toolkit with adolescent talking
points, go to www.healthteamworks.org.
A Brief Intervention is a short motivational conversation to educate and promote health behavior change.
Important: Recognize a person’s readiness to change and respond accordingly.
Use OARS:
Open-ended questions
Affirmations
Reflections
Summaries
Brief Intervention (Brief Negotiated Interview model\\): This model may also be used to address other substance use.
1. Raise the subject.
»» “Would you mind if we talked for a few minutes about your alcohol use?”
›› Ask permission.
›› Avoid arguing or confrontation.
2. Provide feedback.
»» “We know that drinking above certain levels can cause problems such as...”
›› Review reported substance use amounts and patterns.
›› Provide information about substance use and health.
›› Advise to cut down or abstain.
›› Compare the person’s alcohol use to general adult population (see
drinking pyramid below).
»» “What do you think about this information?”
›› Elicit patient’s response.
3. Enhance motivation.
»» “What do you like about your current level of drinking? What do you not like
about your current level of drinking?”
»» “On a scale from 0-10, how important is it for you to decrease your drinking?”
»»
»»
»»
“What makes you a 5 and not a lower number?”
“On a scale from 0-10, how ready are you to decrease your drinking?”
“What would make you more ready to make a change?”
›› Assess readiness to change.
›› Discuss pros and cons.
›› Explore ambivalence.
4. Negotiate and advise.
»» “What’s the next step?”
»» “What are the barriers you anticipate in meeting this goal? How do
you plan to overcome these barriers?”
»» “On a scale from 0-10, how confident are you that you will be able to
make this change?”
»» “What might help you feel more confident?”
›› Negotiate goal.
›› Provide advice and information.
›› Summarize next steps and thank the patient.
012345678910
Importance — Readiness — Confidence
U.S. Adult Alcohol Use Estimate
Potential consequences of risky drinking: multiple health, work and
family issues
Alcohol dependent
Referral to Treatment
Risky drinkers
Brief Intervention
5%
25%
Tobacco Advise and Refer:
Ask permission, then advise every tobacco user to quit with a
personalized health message.
Colorado QuitLine and Other Programs
Refer individuals age 15+ to the Colorado QuitLine
(1-800-QUIT-NOW [1-800-784-8669] or www.coquitline.org):
• Personally tailored quit program
Abstainers or
low-risk drinkers
Positive reinforcement
• Five scheduled, telephone-based coaching sessions
70%
• May include free nicotine replacement therapy (age 18+ and medically eligible)
Information on programs for specific populations and ages: www.myquitpath.com
Order free tools and materials: www.cohealthresources.com
Pharmacotherapy options: HealthTeamWorks Tobacco Cessation and Secondhand
Smoke Exposure Guideline at www.healthteamworks.org/guidelines/tobacco.html
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Referral to treatment
Spectrum:
Screening
Brief Intervention
Brief Therapy
Specialty Treatment
continued:
Brief Therapy: For moderate to high risk use of alcohol or drugs
Substance Use Disorder Treatment: For high risk alcohol or drug use
• Motivational discussion; focused on empowerment and goal setting
• Includes assessment, education, problem-solving, coping strategies,
supportive social environment
• Typically 4-6 sessions, each one approached as though it could be the
last
• Proactive process to facilitate access to specialty care
• Focus on motivating a person to follow-up on referral for further assessment and
possible treatment
• Appropriate level of care may include inpatient, outpatient, residential
• Pharmacotherapy options: www.healthteamworks.org/guidelines/sbirt.html
Referral information in Colorado: http://linkingcare.org
SBIRT is reimbursable if:
Documentation: Key points
• A validated screening tool is used
• It is properly documented
• Time requirement is met
• SBIRT should be documented like any other healthcare service.
• These records may require special permission for release. Consult your
organization’s privacy policy.
• Documented use of a validated screening tool (e.g., AUDIT, DAST, CRAFFT, ASSIST)
required for reimbursement.
See www.healthteamworks.org for up-to-date information.
\\ The Yale Brief Negotiated Interview Manual. D’Onofrio, et al. New Haven, CT: Yale University School of Medicine. 2005.
SBIRT Guideline Supplement:
Prescription Drug Abuse Prevention
page 1 of 2
Those who use prescription drugs inappropriately may have underlying issues that need to be addressed. Clinicians should screen, identify, monitor and work
with patients at risk to prevent potential harms caused by misuse or abuse of prescription drugs. Management of chronic pain and other conditions treated with
medications that have the potential to be abused requires balancing the need for appropriate treatment with prevention of abuse.
This information is intended to assist clinicians in preventing and monitoring for prescription drug misuse and abuse.
Definitions:
Adapted from Katz NP, Adams EH, Chilcoat H, Colucci RD, Comer SD, Goliber P, et al. (2007). Challenges in the Development of Prescription Opioid Abuse-deterrent
Formulations. Clin J Pain. 23(8):648-660.
„„ Prescription drug misuse is “use of a medication (for a medical purpose) other than as directed or as indicated.”
„„ Prescription drug abuse is “the intentional self-administration of a medication for a non-medical purpose.”
Why address prescription drug abuse? (go to www.healthteamworks.org for a full reference list)
„„ Prescription drug abuse is the nation’s fastest growing drug problem (ONDCP).
„„ Poisoning is the leading cause of injury death for adults 35-54 yrs., mainly from prescription drugs (CDC).
„„ Prescription drugs are no safer than illicit drugs, and often easier to obtain.
„„ 1/3 of people age 12+ who used drugs for the first time in 2009 used a prescription drug non-medically (SAMHSA).
„„ 70% of people who abused prescription pain relievers got them from friends and family, 5% from drug dealers or internet (SAMHSA).
„„ Prescription drugs are the second most abused category of illicit drugs after marijuana (University of Michigan).
„„ In 2009, almost 3 times as many Coloradoans died from abusing prescription drugs (445) as from drunk driving crashes (158) (CDPHE).
Screening questions
Many patients will answer truthfully if practices emphasize and ensure the information is handled confidentially.
1. In the past year, have you used or experimented with an illegal drug or a prescription drug for non-medical reasons? Yes = (+) screen
2. Have you taken any prescription drugs not prescribed to you or for a purpose for which they were not prescribed? Yes = (+) screen
ic P a i n D
Su
M
is u
ression
past trauma, family history of dependence, etc.?
„„ Is patient self-medicating for another issue?
Chronic pain, depression and
substance misuse commonly
co-occur. Careful screening will
help clinicians provide the most
appropriate care.
on
ep
„„ Screen for depression using PHQ-2/PHQ-9*, especially in patients presenting with chronic pain.
„„ Does patient have history of abuse of tobacco/alcohol/other drugs or current abuse of a substance?
„„ Does patient have substance abuse/dependence risk factors such as untreated mental health issues,
se Ch
r
Behavioral health considerations
b s ta n ce
Pain management as prevention of abuse: Opioids are not the only drug for pain
Duration
of pain
Acute:
Examples: new fracture, surgical incision
Consider opioids, NSAIDs, acetaminophen.
Chronic:
Examples: frequent headache syndromes, peripheral neuropathy, arthritic joint
Consider certain anti-depressants, anti-convulsants, NSAIDS, acetaminophen.
Somatic: Pain originates from damaged body component, signaling pain appropriately.
Typical descriptors: sharp, pressure, gnawing
Character
of pain
Neuropathic: Pain originates from damaged neural pathway, signaling pain
inappropriately.
Typical descriptors: shooting, electric shock, pins and needles, tingling
If neuropathic pain, consider anti-depressants and anti-convulsants.
Consider referring to a Pain Management
Specialist when:
„„ Clinical presentation does not fit the
response.
„„ The quantity of drugs a patient consumes is
rapidly increasing.
„„ Pain is not improving despite current dose or
increased dose.
Alternate modalities
to manage pain:
„„ Meditation
„„ Physical Therapy
„„ Yoga
„„ Massage
„„ Reiki
„„ Biofeedback
„„ Relaxation
„„ Tai Chi
„„ Antidepressant
„„ Anticonvulsant
*See Depression in Adults: Diagnosis and Treatment Guideline at: www.healthteamworks.org/guidelines/depression.html.
This supplement is designed to assist clinicians with prevention of prescription drug misuse and abuse. It is not intended to replace a clinician’s judgment or establish a protocol for all patients with a particular condition.
For references, important updates and copies of the supplement go to www.healthteamworks.org or call (303) 446-7200 or 1-866-401-2092. Funding for this supplement was provided by SAMHSA.
Completed September 2011.
Sedative hypnotics abuse
Alcohol risk
„„ Benzodiazepines have a synergistic effect with opioids and alcohol.
»» Benzodiazepines with opioids or alcohol put patient at increased risk for
„„ Alcohol + opioids or benzodiazepines have a synergistic effect.
„„ Consider a patient’s alcohol use when prescribing opioids. Reinforce the
„„ Often used with alcohol to increase the synergistic effect.
„„ Only approved for short-term use in insomnia.
„„ Contraindicated to use these drugs with COPD or sleep apnea.
„„ There is no known safe amount of alcohol while taking sedatives or
CNS depression or respiratory depression.
importance of not using simultaneously (especially with benzodiazepines).
opioids.
Stimulant abuse
„„ Abused primarily for recreation and academic enhancements.
„„ Before prescribing, consider gathering references from parents and teachers to discourage drug-seeking. Look at past records and be willing to say “no.”
„„ Talk with children about not revealing their prescription use to their friends.
„„ Give an appropriate diagnosis, amount of medicine, and instructions for medications.
Note: some practices (i.e. student health centers) require testing-based diagnosis of ADD/ADHD before prescribing.
Steps to reduce risks
For Your Practice
„„ Screen: Screener and Opioid Assessment for Patients with Pain, Opioid Risk Tool, Pain Medication
Questionnaire (see below for links).
„„ Check: Colorado Prescription Drug Monitoring Program (PDMP) at www.coloradopdmp.org to
ensure patient is not receiving similar medications from other sources, for evidence of prescriptions
you did not write, or stolen prescription pads on your profile.
„„ Watch for potential signs of misuse: multiple use on PDMP, calling after hours, ER/urgent care
visits, manipulative/demanding, lost/stolen prescriptions.
„„ Monitor use: when patient calls in for refills, do a phone screen to review side effects, interactions
and to monitor the use of the drug.
„„ Use contracts: consider having patient sign a Pain Medication Contract. See example at
www.healthteamworks.org.
„„ Safeguard Rx access: Keep pads in your pocket or locked up and do not share passwords with
others. Use scripts that can’t be photocopied.
For Your Patients
„„ Address patient concerns: (i.e., pain).
„„ Trust your clinical judgment: don’t completely rely on
pain scale.
„„ Avoid opioid drugs: educate yourself about responsible
opioid prescribing and alternative therapies for pain.
„„ Warn patients: many medications have the potential for
creating dependence and other harmful side effects such
as constipation, central apnea, hormonal imbalance,
dependence, and withdrawal.
„„ Screen: for sleep apnea, pregnancy and breast feeding
which can place patient/child at an increased risk for
death if combined with opioid use.
„„ Plan: for a step-down process.
Safeguarding of medications: tips for patients and caregivers
„„ Sharing your prescriptions with others is against the law.
„„ Don’t openly discuss your medications with others.
„„ Keep medications in a safe, locked place (not in medicine/kitchen cabinets).
„„ Treat prescription drugs as you would cash or credit cards.
„„ Many medications have a high street value and are often stolen from homes
or vehicles.
„„ Some over-the-counter medications (i.e., pseudoephedrine,
dextromethorphan) have the potential for abuse and should be secured.
Proper medication disposal
Approximately 20% of all prescription medications are unused. Proper disposal is key to decreasing abuse.
O
Controlled
„„ Controlled medications can only be given to a uniformed law enforcement officer for safe disposal.
„„ According to the FDA, some controlled substances should be flushed. For a list: www.fda.gov.
„„ Be aware of community pharmaceutical take back programs sponsored by law enforcement.
o flush!
Kt
Non-Controlled
„„ Be aware of community pharmaceutical take back programs.
„„ Take unused, unneeded prescription drugs out of original containers, mix with an undesirable substance (e.g., used coffee grounds or kitty litter),
put in nondescript containers or sealed bags and throw them in the trash.
„„ Colorado Medication Disposal Pilot Project: www.cdphe.state.co.us/hm/medtakeback/index.htm
Resources for prescribers
„„ Food and Drug Administration: www.fda.gov
„„ Opioid Risk Tool (ORT): www.opioidrisk.com/node/884
„„ Screener & Opioid Assessment for Patients with Pain (SOAPP):
www.painedu.org/soap.asp
„„ Pain Medication Questionnaire: www.opioidrisk.com/node/943
„„ Colorado PDMP: www.coloradopdmp.org
Books
„„ Avoiding Opioid Abuse While Managing Pain by Lynn R. Webster, MD, and Beth
Dove
„„ Responsible Opioid Prescribing by Scott M. Fishman, MD
Referral to Treatment
„„ Division of Behavioral Health: http://linkingcare.org
„„ See HealthTeamWorks SBIRT Guideline Referral to Treatment section
Alcohol and your health
Research-based information from the
National Institutes of Health
U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES
NIH...Turning Discovery Into Health®
“Sometimes we do things out of habit and we don’t really stop to think
about it. This made me think about my choices.”
“It emphasized that drinking is not bad in and of itself—it’s how much
you’re doing it and how it’s affecting your life.”
“I thought the strategies for cutting down were really good.
It gives you tools to help yourself.”
These are comments from social drinkers who reviewed Rethinking
Drinking in focus testing. We welcome your comments as well. Send an
email to [email protected] or call 301–443–3860.
For an online version of this booklet with interactive
features and additional resources, visit
RethinkingDrinking.niaaa.nih.gov
RETHINKING DRINKING
Do you think you may drink too much at times? Do you think “everyone” drinks a lot?
See below for results from a nationwide survey of 43,000 adults by the National
Institutes of Health on alcohol use and its consequences.
Alcohol use by adults in the United States*
7 in 10 adults
always drink at
low-risk levels
or
do not drink
at all
37%
always drink
at low-risk
levels
*Although the minimum legal drinking age in the U.S. is 21, this survey included people aged 18 or older.
For anyone who drinks, Rethinking Drinking offers valuable, research-based information.
The first part, How much is too much?, answers these questions and more:
• What’s “low-risk” drinking versus “at-risk” or “heavy” drinking?
• Why is being able to “hold your liquor” a concern?
• What are signs that drinking is causing harm?
Thinking about a change?
35%
don’t drink
at all
28%
drink at
heavy or
at-risk
levels
3 in 10 adults
drink at levels
that put them
at risk for
alcoholism,
liver disease, and
other problems
How much is too much?
Do you enjoy a drink now and then? Many of us do, often when socializing with
friends and family. Drinking can be beneficial or harmful, depending on your age and
health status, the situation, and, of course, how much you drink.
Many heavy drinkers do not have alcohol-related problems yet and can reduce their
risk of harm by cutting back. For the nearly 18 million Americans who have alcoholism
or related problems, however, it’s safest to quit.
The second part of this booklet, Thinking about a change?, offers tips, tools, and
resources for people who choose to cut down or quit. Success is likely for those who
persist in their efforts. Even for those with alcoholism, studies show that most do
recover, often without professional treatment.
What do you think about taking a look at your drinking habits and how they may affect
your health? Rethinking Drinking can help you get started.
1
HOW MUCH IS TOO MUCH?
What counts as a drink?
Many people are surprised to learn what counts as a drink. In the United States,
a “standard” drink is any drink that contains about 0.6 fluid ounces or 14 grams of
“pure” alcohol. Although the drinks pictured below are different sizes, each contains
approximately the same amount of alcohol and counts as a single drink.
12 fl oz of
regular beer
=
8–9 fl oz of
malt liquor
(shown in a
12 oz glass)
about 5%
alcohol
=
about 7%
alcohol
5 fl oz of
table wine
about 12%
alcohol
=
1.5 fl oz shot of
80-proof spirits
(“hard liquor”—
whiskey, gin, rum,
vodka, tequila, etc.)
about 40%
alcohol
The percent of “pure” alcohol, expressed here as alcohol by volume (alc/vol), varies by beverage.
How many drinks are in common containers?
Below is the approximate number of standard drinks in different sized containers of
regular beer malt liquor table wine 80-proof spirits or “hard liquor”
12 fl oz = 1
12 fl oz = 1½ 750 ml (a regular a shot (1.5 oz glass/50 ml bottle) = 1
16 fl oz = 1 16 fl oz = 2
wine bottle)= 5 a mixed drink or cocktail
= 1 or more
22 fl oz = 2½
200 ml (a “half pint”)
= 4½
22 fl oz = 2
40 fl oz = 3 40 fl oz = 4½
375 ml (a “pint” or “half bottle”)= 8½
750 ml (a “fifth”)
= 17
The examples shown on this page serve as a starting point for comparison. For
different types of beer, wine, or malt liquor, the alcohol content can vary greatly.
Some differences are smaller than you might expect, however. Many light beers,
for example, have almost as much alcohol as regular beer—about 85% as much,
or 4.2% versus 5.0% alcohol by volume (alc/vol), on average.
Although the standard drink sizes are helpful for following health guidelines, they
may not reflect customary serving sizes. A mixed drink, for example, can contain one,
two, or more standard drinks, depending on the type of spirits and the recipe.
2
RethinkingDrinking.niaaa.nih.gov
What’s your drinking pattern?
1.On any day in the past year, have you ever had
•For MEN: more than 4 drinks?
yes
no
•For WOMEN: more than 3 drinks?
yes
no
2. Think about your typical week:
(a)
• On average, how many days a week do you drink alcohol? • On a typical drinking day, how many drinks do you have?
X
How much is too much?
Using the drink sizes on page 2, answer the questions below:
(b)
(multiply a x b)
weekly average =
Sometimes even a little is too much
Even moderate levels of drinking (up to 2 drinks per day for men or 1 for women) can
be too much in some circumstances. It’s safest to avoid alcohol if you are
•
•
•
•
planning to drive a vehicle or operate machinery
taking medications that interact with alcohol
managing a medical condition that can be made worse by drinking
pregnant or trying to become pregnant
Can you “hold your liquor”?
If so, you may be at greater risk. For some people, it takes quite a few
drinks to get a buzz or feel relaxed. Often they are unaware that being able to
“hold your liquor” isn’t protection from alcohol problems, but instead a reason
for caution. They tend to drink more, socialize with people who drink a lot,
and develop a tolerance to alcohol. As a result, they have an increased risk for
developing alcoholism. The higher alcohol levels can also cause liver, heart, and
brain damage that can go unnoticed until it’s too late. And all drinkers need to
be aware that even moderate amounts of alcohol can significantly impair driving
performance, even when they don’t feel a buzz from drinking.
3
What’s “low-risk” drinking?
A major nationwide survey of 43,000 U.S. adults by the National Institutes of Health
shows that only about 2 in 100 people who drink within both the “single-day” and
weekly limits below have alcoholism or alcohol abuse. How do these “low-risk”
levels compare with your drinking pattern from page 3?
MEN
WOMEN
No more than
No more than
Low-risk drinking limits
3
1 2
10
9
8
6 7
6 17
1
4 5
5
1
13 14
24
11 12
22 23
20 21 9 30 31
18 19
2
27 28
25 26
On any
single
DAY
4
drinks on any day
** AND **
** AND **
No more than
Per
WEEK
3
drinks on any day
14
drinks per week
No more than
7
drinks per week
To stay low risk, keep within BOTH the single-day AND weekly limits.
“Low risk” is not “no risk.” Even within these limits, drinkers can have problems if they
drink too quickly, have health problems, or are older (both men and women over 65 are
generally advised to have no more than 3 drinks on any day and 7 per week). Based on
your health and how alcohol affects you, you may need to drink less or not at all.
What’s “heavy” or “at-risk” drinking?
For healthy adults in general, drinking more than the single-day or weekly amounts
shown above is considered “at-risk” or “heavy” drinking. About 1 in 4 people who drink
this much already has alcoholism or alcohol abuse, and the rest are at greater risk for
developing these and other problems.
It makes a difference both how much you drink on any day and how often you have
a “heavy drinking day”—that is, more than 4 drinks in a day for men or more than 3
drinks for women. The more drinks in a day and the more heavy drinking days over
time, the greater the chances for problems (see “What’s the harm?” on the next page).
Why are women’s low-risk limits different from men’s?
Research shows that women start to have alcohol-related problems at lower
drinking levels than men do. One reason is that, on average, women weigh less
than men. In addition, alcohol disperses in body water, and pound for pound,
women have less water in their bodies than men do. So after a man and woman
of the same weight drink the same amount of alcohol, the woman’s blood alcohol
concentration will tend to be higher, putting her at greater risk for harm.
4
How much do U.S. adults drink?
The majority—7 out of 10—either abstain or always drink within low-risk limits.
Which group are you in?
9%
19 %
drink more than both the single-day
limits and the weekly limits
Highest risk
drink more than either the single-day
Increased risk
limits or the weekly limits
37 %
always drink within low-risk limits
35 %
never drink alcohol
Low risk
How much is too much?
Drinking patterns in U.S. adults
—
What’s the harm?
Not all drinking is harmful. You may have heard that regular light to moderate drinking
(from ½ drink a day up to 1 drink a day for women and 2 for men) can even be good
for the heart. With at-risk or heavy drinking, however, any potential benefits are
outweighed by greater risks.
Injuries. Drinking too much increases your chances of being injured or even killed.
Alcohol is a factor, for example, in about 60% of fatal burn injuries, drownings, and
homicides; 50% of severe trauma injuries and sexual assaults; and 40% of fatal
motor vehicle crashes, suicides, and fatal falls.
Health problems. Heavy drinkers have a greater risk of liver disease, heart disease,
sleep disorders, depression, stroke, bleeding from the stomach, sexually transmitted
infections from unsafe sex, and several types of cancer. They may also have problems
managing diabetes, high blood pressure, and other conditions.
Birth defects. Drinking during pregnancy can cause brain damage and other serious
problems in the baby. Because it is not yet known whether any amount of alcohol is
safe for a developing baby, women who are pregnant or may become pregnant should
not drink.
Alcohol use disorders. Generally known as alcoholism and alcohol abuse, alcohol
use disorders are medical conditions that doctors can diagnose when a patient’s
drinking causes distress or harm. In the United States, about 18 million people have
an alcohol use disorder. See the next page for symptoms.
5
What are symptoms of an alcohol use disorder?
See if you recognize any of these symptoms in yourself. In the past year, have you
had times when you ended up drinking more, or longer, than you intended?
more than once wanted to cut down or stop drinking, or tried to, but couldn’t?
more than once gotten into situations while or after drinking that increased
your chances of getting hurt (such as driving, swimming, using machinery,
walking in a dangerous area, or having unsafe sex)?
had to drink much more than you once did to get the effect you want? Or found
that your usual number of drinks had much less effect than before?
continued to drink even though it was making you feel depressed or anxious or
adding to another health problem? Or after having had a memory blackout?
spent a lot of time drinking? Or being sick or getting over other aftereffects?
continued to drink even though it was causing trouble with your family or
friends?
found that drinking—or being sick from drinking—often interfered with taking
care of your home or family? Or caused job troubles? Or school problems?
given up or cut back on activities that were important or interesting to you, or
gave you pleasure, in order to drink?
more than once gotten arrested, been held at a police station, or had other
legal problems because of your drinking?
found that when the effects of alcohol were wearing off, you had withdrawal
symptoms, such as trouble sleeping, shakiness, restlessness, nausea, sweating,
a racing heart, or a seizure? Or sensed things that were not there?
If you don’t have symptoms, then staying within the low-risk drinking limits on
page 4 will reduce your chances of having problems in the future.
If you do have any symptoms, then alcohol may already be a cause for concern. The
more symptoms you have, the more urgent the need for change. A health professional
can look at the number, pattern, and severity of symptoms to see whether an alcohol
use disorder is present and help you decide the best course of action.
Thinking about a change? The next section may help.
Note: These questions are based on symptoms for alcohol use disorders in the American Psychiatric
Association’s Diagnostic and Statistical Manual (DSM) of Mental Disorders, Fourth Edition. The DSM is
the most commonly used system in the United States for diagnosing mental health disorders.
6
THINKING ABOUT A CHANGE?
THINKING ABOUT A CHANGE?
It’s up to you
It’s up to you as to whether and when to change your drinking. Other people may be
able to help, but in the end it’s your decision. Weighing your pros and cons can help.
Pros: What are some reasons why you might want to make a change?
to improve my health
to lose weight or get fit
to improve my relationships
to save money
to avoid hangovers
to avoid more serious problems
to do better at work or school
to meet my own personal standards
Cons: What are some possible reasons why you might not want to change?
Compare your pros and cons. Put extra check marks by the most important one(s).
Is there a difference between where you are and where you want to be?
Ready . . . or not?
Are you ready to change your drinking? If so, see the next sections for support. But
don’t be surprised if you continue to have mixed feelings. You may need to re-make
your decision several times before becoming comfortable with it.
If you’re not ready to change yet, consider these suggestions in the meantime:
• Keep track of how often and how much you’re drinking.
• Notice how drinking affects you.
• Make or re-make a list of pros and cons about changing.
• Deal with other priorities that may be in the way of changing.
• Ask for support from your doctor, a friend, or someone else you trust.
Don’t wait for a crisis or to “hit bottom.”
When someone is drinking too much, making a change earlier is likely to be
more successful and less destructive to individuals and their families.
8
RethinkingDrinking.niaaa.nih.gov
To cut down or to quit . . .
If you’re considering changing your drinking, you’ll need to decide whether to cut
down or to quit. It’s a good idea to discuss different options with a doctor, a friend,
or someone else you trust. Quitting is strongly advised if you
•
•
•
•
•
try cutting down but cannot stay within the limits you set
have had an alcohol use disorder or now have symptoms (see page 6)
have a physical or mental condition that is caused or worsened by drinking
are taking a medication that interacts with alcohol
are or may become pregnant
If you do not have any of these conditions, talk with your doctor to determine whether
you should cut down or quit based on factors such as
•
•
•
•
family history of alcohol problems
your age
whether you’ve had drinking-related injuries
symptoms such as sleep disorders and sexual dysfunction
If you choose to cut down, see the low-risk drinking limits on page 4.
Even when you have committed to change, you still may have mixed feelings at times.
Making a written “change plan” will help you to solidify your goals, why you want to
reach them, and how you plan to do it. A sample form is provided on page 14, or you
can fill out one online at the Rethinking Drinking Web site.
Reinforce your decision with reminders.
Enlist technology to help. Change can be hard, so it helps to have concrete
reminders of why and how you’ve decided to do it. Some standard options include
carrying a change plan in your wallet or posting sticky notes at home. If you have
a computer or mobile phone, consider these high-tech ideas:
Thinking about a change?
Planning for change
• Fill out a “change plan” online at the Rethinking Drinking Web site, email it
to your personal (non-work) account, and review it weekly.
• Store your goals, reasons, or strategies in your mobile phone in short text
messages or notepad entries that you can retrieve easily when an urge hits.
• Set up automated mobile phone or email calendar alerts that deliver
reminders when you choose, such as a few hours before you usually go out.
• Create passwords that are motivating phrases in code, which you’ll type each
time you log in, such as 1Day@aTime, 1stThings1st!, or 0Pain=0Gain.
9
Strategies for cutting down
Small changes can make a big difference in reducing your chances of having alcoholrelated problems. Here are some strategies to try. Check off perhaps two or three
to try in the next week or two, then add some others as needed. If you haven’t
made progress after 2 to 3 months, consider quitting drinking altogether, seeking
professional help, or both.
Keep track.
Keep track of how much you drink. Find a way that works for you, such as a 3x5”
card in your wallet (see page 15 for samples), check marks on a kitchen calendar,
or notes in a mobile phone notepad or personal digital assistant. Making note of
each drink before you drink it may help you slow down when needed.
Count and measure.
Know the “standard” drink sizes so you can count your drinks accurately (see
page 2). Measure drinks at home. Away from home, it can be hard to keep track,
especially with mixed drinks. At times you may be getting more alcohol than
you think. With wine, you may need to ask the host or server not to “top off” a
partially filled glass.
Set goals.
Decide how many days a week you want to drink and how many drinks you’ll
have on those days. It’s a good idea to have some days when you don’t drink.
Drinkers with the lowest rates of alcohol use disorders stay within these limits
(also shown on page 4): For men, no more than 4 drinks on any day and 14 per
week; and for women, no more than 3 drinks on any day and 7 per week. Both
men and women over age 65 generally are advised to have no more than 3 drinks
on any day and 7 per week. Depending on your health status, your doctor may
advise you to drink less or not at all.
Pace and space.
When you do drink, pace yourself. Sip slowly. Have no more than one standard
drink with alcohol per hour. Have “drink spacers”—make every other drink a
nonalcoholic one, such as water, soda, or juice.
Include food.
10
Don’t drink on an empty stomach. Have some food so the alcohol will be
absorbed into your system more slowly.
Find alternatives.
If drinking has occupied a lot of your time, then fill free time by developing new,
healthy activities, hobbies, and relationships or renewing ones you’ve missed.
If you have counted on alcohol to be more comfortable in social situations,
manage moods, or cope with problems, then seek other, healthy ways to deal
with those areas of your life.
Avoid “triggers.”
What triggers your urge to drink? If certain people or places make you drink
even when you don’t want to, try to avoid them. If certain activities, times of
day, or feelings trigger the urge, plan something else to do instead of drinking.
If drinking at home is a problem, keep little or no alcohol there.
Plan to handle urges.
Know your “no.”
You’re likely to be offered a drink at times when you don’t want one. Have a
polite, convincing “no, thanks” ready. The faster you can say no to these offers,
the less likely you are to give in. If you hesitate, it allows you time to think of
excuses to go along.
Thinking about a change?
When you cannot avoid a trigger and an urge hits, consider these options:
Remind yourself of your reasons for changing (it can help to carry them in
writing or store them in an electronic message you can access easily). Or
talk things through with someone you trust. Or get involved with a healthy,
distracting activity, such as physical exercise or a hobby that doesn’t involve
drinking. Or, instead of fighting the feeling, accept it and ride it out without
giving in, knowing that it will soon crest like a wave and pass.
Tools to help you manage urges to drink and build drink refusal skills are available on
the Rethinking Drinking Web site.
If you want to quit drinking—
The four strategies on this page are especially helpful. But if you think you
may be dependent on alcohol and decide to stop drinking completely, don’t go
it alone. Sudden withdrawal from heavy drinking can be life threatening. Seek
medical help to plan a safe recovery.
11
Support for quitting
The suggestions in this section will be most useful for people who have become
dependent on alcohol, and thus may find it difficult to quit without some help. Several
proven treatment approaches are available. One size doesn’t fit all, however. It’s a
good idea to do some homework on the Internet or at the library to find social and
professional support options that appeal to you, as you are more likely to stick with
them (see also Resources on the inside back cover). Chances are excellent that you’ll
pull together an approach that works for you.
Social support
One potential challenge when people stop drinking is rebuilding a life without
alcohol. It may be important to
•
•
•
•
educate family and friends
develop new interests and social groups
find rewarding ways to spend your time that don’t involve alcohol
ask for help from others
When asking for support from friends or significant others, be specific. This could
include
•
•
•
•
•
not offering you alcohol
not using alcohol around you
giving words of support and withholding criticism
not asking you to take on new demands right now
going to a group like Al-Anon
Consider joining Alcoholics Anonymous or another mutual support group (see
Resources). Recovering people who attend groups regularly do better than those who
do not. Groups can vary widely, so shop around for one that’s comfortable. You’ll get
more out of it if you become actively involved by having a sponsor and reaching out to
other members for assistance.
Feeling depressed or anxious?
It’s common for people with alcohol problems to feel depressed or anxious. Mild
symptoms may go away if you cut down or stop drinking. See a doctor or mental
health professional if symptoms persist or get worse. If you’re having suicidal
thoughts, call your health care provider or go to the nearest emergency room
right away. Effective treatment is available to help you through this difficult time.
12
Professional support
Advances in the treatment of alcoholism mean that patients now have more choices
and health professionals have more tools to help.
Medications to treat alcoholism. Newer medications can make it easier to quit
drinking by offsetting changes in the brain caused by alcoholism. These options
(naltrexone, topiramate, and acamprosate) don’t make you sick if you drink, as does
an older medication (disulfiram). None of these medications are addictive, so it’s fine
to combine them with support groups or alcohol counseling.
A major clinical trial recently showed that patients can now receive effective alcohol
treatment from their primary care doctors or mental health practitioners by combining
the newer medications with a series of brief office visits for support. See Resources
for more information.
Specialized, intensive treatment programs. Some people will need more
intensive programs. See Resources for a treatment locator. If you need a referral
to a program, ask your doctor.
Don’t give up.
Thinking about a change?
Alcohol counseling. “Talk therapy” also works well. There are several counseling
approaches that are about equally effective­—12 step, cognitive-behavioral,
motivational enhancement, or a combination. Getting help in itself appears to be
more important than the particular approach used, as long as it offers empathy,
avoids heavy confrontation, strengthens motivation, and provides concrete ways
to change drinking behavior.
Changing habits such as smoking, overeating, or drinking too much can take
a lot of effort, and you may not succeed with the first try. Setbacks are common,
but you learn more each time. Each try brings you closer to your goal.
Whatever course you choose, give it a fair trial. If one approach doesn’t work,
try something else. And if a setback happens, get back on track as quickly
as possible.
In the long run, your chances for success are good. Research shows that most
heavy drinkers, even those with alcoholism, either cut back significantly or quit.
For tools to help you make and maintain a change, visit the Rethinking Drinking
Web site.
13
Ready to begin?
If so, start by filling out the change plan below or online at the Rethinking Drinking
Web site, where you can print it out or email it to yourself. If you are cutting down
as opposed to quitting, you can use the drinking tracker cards on the next two pages.
Change plan
Goal:
I want to drink no more than ___ drink(s) on any day and
no more than ___ drink(s) per week (see page 4 for low-risk limits) or
I want to stop drinking
Timing: I will start on this date:
Reasons: My most important reasons to make these changes are:
Strategies: I will use these strategies (see pages 10–11):
People: The people who can help me are (names and how they can help):
Signs of success: I will know my plan is working if:
Possible roadblocks: Some things that might interfere and how I’ll handle them:
14
Drinking tracker cards
If you want to cut back on your drinking, start by keeping track of every drink. Below
are two sample forms you can cut out or photocopy and keep with you. Either one can
help make you aware of patterns, a key step in planning for a change. The “4-week
tracker” is a simple calendar form. If you mark down each drink before you have it,
this can help you slow down if needed. The “drinking analyzer” can help you examine
the causes and consequences of your drinking pattern. Try one form, or try both to see
which is more helpful. These are also available on the Rethinking Drinking Web site.
4-week tracker
GOAL: No more than ____ drinks on any day and ____ per week.
Week
starting
Su
M
T
W
Th
F
Sa
Total
___/___
Thinking about a change?
___/___
___/___
___/___
Drinking analyzer
Date
Situation (people, place) or Type of
trigger (incident, feelings) drink(s) Amount
Consequence
(what happened?)
15
Drinking tracker cards (continued)
These are the same cards as on the previous page. If you cut one out, you will have
the drinking analyzer on one side and the 4-week tracker on the other side.
Drinking analyzer
Date
Situation (people, place) or Type of
trigger (incident, feelings) drink(s) Amount
Consequence
(what happened?)
4-week tracker
GOAL: No more than ____ drinks on any day and ____ per week.
Week
starting
___/___
___/___
___/___
___/___
16
Su
M
T
W
Th
F
Sa
Total
Resources
Professional help
Mutual-help groups
Your regular doctor. Primary care and
Alcoholics Anonymous (AA)
www.aa.org
212–870–3400 or check your local
phone directory under “Alcoholism”
mental health practitioners can provide
effective alcoholism treatment by combining
new medications with brief counseling
visits. See “Helping Patients Who Drink Too
Much” at www.niaaa.nih.gov/guide or call
301–443–3860.
Specialists in alcoholism. For specialty
addiction treatment options, contact your
doctor, health insurance plan, local health
department, or employee assistance program.
Other resources include
Medical and non-medical
addiction specialists
American Academy of Addiction
Psychiatry
www.aaap.org
401–524–3076
American Psychological
Association
1–800–964–2000 (ask for your state’s
referral number to find psychologists
with addiction specialties)
American Society of Addiction
Medicine
301–656–3920 (ask for the phone
number of your state’s chapter)
NAADAC Substance Abuse
Professionals
www.naadac.org
1–800–548–0497
National Association of Social
Workers
www.helpstartshere.org
(search for social workers with
addiction specialties)
Treatment facilities
Substance Abuse Treatment
Facility Locator
www.findtreatment.samhsa.gov
1–800–662–HELP
Moderation Management
www.moderation.org
212–871–0974
Secular Organizations for Sobriety
www.secularsobriety.org
323–666–4295
SMART Recovery
www.smartrecovery.org
440–951–5357
Women for Sobriety
www.womenforsobriety.org
215–536–8026
Groups for family and friends
Al-Anon/Alateen
www.al-anon.alateen.org
1–888–425–2666 for meetings
Adult Children of Alcoholics
www.adultchildren.org
310–534–1815
Information resources
National Institute on Alcohol Abuse
and Alcoholism
www.niaaa.nih.gov
301–443–3860
National Institute on Drug Abuse
www.nida.nih.gov
301–443–1124
National Institute of Mental Health
www.nimh.nih.gov
1–866–615–6464
National Clearinghouse for Alcohol
and Drug Information
www.ncadi.samhsa.gov
1–800–729–6686
For additional resources, visit RethinkingDrinking.niaaa.nih.gov
U
AN
VICES • U
SER
SA
T
OF
HEA
LT H A N
DH
M
D E PA R
TM
NIH Publication No. 13-3770
Published 2010
EN
SBIRT Basic
AUDIT-C Protocol w/Scripting
McPherson &Goplerud 2010
Open by saying: “How can I help you today?...proceed with Intake
Introduce screening by saying: “We ask all our clients intake questions to help us better understand who you are and
what your needs might be. As part of our holistic approach and as a preventive measure, we also ask some screening
questions of all our members. Your answers will remain confidential”...proceed with screening [embed alcohol questions,
e.g., start with depression, go to alcohol, drug use, then close with stress]
Conduct AUDIT-C Hazardous Use Prescreen (3 questions)
Q1: Frequency of drinking
Q2: Quantity in a typical day
Q3: Frequency of heavy use
Record responses and add Q1+Q2+Q3, then Enter AUDIT-C score
If client refuses at any point, indicate “Refused AUDIT-C”
If AUDIT-C = <4 for men, <3 for women
and adults over age 65
Follow NEGATIVE PRESCREEN Procedures:
• AUDIT-C score feedback
• Alcohol education
• Normative feedback
Brief Intervention RESPONSE
• "From your responses, your drinking is in a
healthy range, which means that you are at lower
risk for many health and emotional concerns than
those who drink at higher ranges. The U.S.
recommended guidelines for low-risk drinking for
women and adults over 65 is no more than 1 drink
per day or 7 drinks per week, and for men no more
than 2 drinks per day or 14 drinks per week. Most
people, about 72% of adults in the U.S. never
exceed these daily or weekly limits. Would you like
me to send you some more information on healthy
drinking patterns?"
If yes, offer to email booklet and links
•
“Tips for Cutting Down on Drinking” booklet
http://pubs.niaaa.nih.gov/publications/Tips/tips.p
df
• EAP website
Document “BI provided” or “BI refused”
Document “alcohol education materials provided”
Close alcohol SBI:
• “Thank you for taking a few minutes to talk with
me.”
STOP alcohol BI, continue EAP intake
If AUDIT-C = 4+ for men, 3+ for women and adults over age 65
Follow POSITIVE PRESCREEN Procedures:
• AUDIT-C score feedback
• Alcohol Education
• Normative Feedback
• Simple Advice
Brief Intervention RESPONSE
AUDIT-C Score Feedback
• "From your responses, your drinking may put you at higher risk for health
and emotional concerns than those who drink at lower ranges. These
questions have been given to thousands of people, so you can compare your
drinking to others. Normal scores are 0-4 for men and 0-3 for women and
anyone over age 65, which is low-risk drinking. Your score was [#]…on a
scale of 0-12 which places you in the category for higher risk of harm.”
Alcohol Education
• “Unhealthy alcohol use can put you at risk for injury, accidents, and health
problems such as diabetes, cancer, insomnia, high blood pressure, stroke,
heart and gastrointestinal problem, depression and other conditions.”
• “The U.S. recommended guidelines for low-risk drinking for women and
adults over the age of 65 is no more than 1 drink per day (or 7 drinks per
week) and for men no more than 2 drinks per day (or 14 drinks per week).
Normative Feedback
• “Most people, about 72% of adults in the U.S. never exceed these daily or
weekly limits.”
Simple Advice
• “Reducing your alcohol consumption to safer drinking levels can decrease
your risk.”
Provide Alcohol Educational Materials
• "Could I send you some information about healthy drinking?"
If yes, offer to email booklets and links to websites:
•
•
•
•
Rethinking Drinking booklet
http://pubs.niaaa.nih.gov/publications/RethinkingDrinking/Rethinking_Drinking.pdf
Rethinking Drinking: Alcohol and Your Health website
http://rethinkingdrinking.niaaa.nih.gov/; and
“Tips for Cutting Down on Drinking” booklet
http://pubs.niaaa.nih.gov/publications/Tips/tips.pdf
EAP/BH website and other materials as appropriate: (e.g., Mixing Alcohol and
Medication; Alcohol and Women; Young Teens and Drinking; Alcohol and Older Adults;
Prevention for Children)
Document “BI provided” or “BI refused”,“alcohol education materials provided”
Close alcohol SBI:
•
“Thank you for taking a few minutes to talk with me.”
STOP alcohol BI, continue EAP intake
SBIRT MI-Informed
AUDIT with 3 Risk Levels Protocol w/Scripting
McPherson &Goplerud 2010
Open by saying: “How can I help you today?...proceed with Intake
Introduce screening by saying: “We ask all our clients intake questions to help us better understand who you are and
what your needs might be. As part of our holistic approach and as a preventive measure, we also ask some screening
questions of all our members. Your answers will remain confidential”...proceed with screening [embed alcohol questions,
e.g., start with depression, go to alcohol, drug use, then close with stress]
Conduct AUDIT-C Hazardous Use Prescreen (3 questions)
Q1: Frequency of drinking
Q2: Quantity in a typical day
Q3: Frequency of heavy use
Record responses and add Q1+Q2+Q3, then Enter AUDIT-C score
If client refuses at any point, indicate “Refused AUDIT-C”
If AUDIT-C = <4 for men, <3 for women
and adults over age 65
If AUDIT-C = 4+ for men, 3+ for women and adults over age 65
Follow POSITIVE PRESCREEN Procedures:
• Complete remaining AUDIT items Q4 – Q10
• Record responses and add ALL AUDIT items (Q1-Q10), Enter total score
• Identify Level of Risk (Low, Moderate, High)
• If member refuses at any point, indicate “Member refused AUDIT”
Follow NEGATIVE PRESCREEN Procedures:
• AUDIT-C score feedback
• Alcohol education
• Normative feedback
Brief Intervention RESPONSE
• "From
your responses, your drinking is in a
•
healthy range, which means that you are at lower
risk for many health and emotional concerns than
those who drink at higher ranges. The U.S.
recommended guidelines for low-risk drinking for
women and adults over 65 is no more than 1 drink
per day or 7 drinks per week, and for men no more
than 2 drinks per day or 14 drinks per week. Most
people, about 72% of adults in the U.S. never
exceed these daily or weekly limits. Would you like
me to send you some more information on healthy
drinking patterns?"
If yes, offer to email booklet and links
•
“Tips for Cutting Down on Drinking” booklet
http://pubs.niaaa.nih.gov/publications/Tips/tips.p
df
• EAP website
Document “BI provided” or “BI refused”
Document “alcohol education materials provided”
Close alcohol SBI:
• “Thank you for taking a few minutes to talk with
me.”
Risk Level
Intervention
AUDIT
score*
Level I Low Risk
ƒ AUDIT score feedback
ƒ Alcohol Education
ƒ Normative Feedback
[no follow-up]
0-7
Level II ƒ AUDIT score feedback
Moderate Risk ƒ Alcohol Education
ƒ Normative Feedback
ƒ Simple Advice
ƒ Referral to EAP Provider
and/or other resources
ƒ Schedule Follow-up
Level IIIƒ AUDIT score feedback
High Risk
ƒ Alcohol Education
ƒ Normative Feedback
ƒ Simple Advice
ƒ Referral to Appropriate
Level of Care (Specialist
for Dx Eval, Tx, Alc
DM, Community
Resources)
ƒ Schedule Follow-up
STOP alcohol BI, continue EAP intake
CONTINUE TO NEXT PAGE
Level I
See “Follow
Negative
Prescreen”
Level II
8-19
Continue to
“Brief
Intervention
Response”
Level III
20-40
Continue to
“Brief
Intervention
Response”
Level II/Moderate
(Score 8-19)
Level III/High
(Score 20-40)
MI-Informed Brief Intervention for Risky Drinking
RESPONSE ….
Use your MI skills (OARS) to engage the member in
conversation about alcohol use…
9 Open-ended Questions
9 Affirming Statements
9 Reflective Listening
9 Summarizing
AUDIT Score Feedback…in a non-judgmental manner
• "From your responses, your drinking puts you at
higher risk for many health and emotional concerns
than those who drink at lower ranges. These questions
have been given to thousands of people, so you can
compare your drinking to others. Your score was
[#]…on a scale of 0-40 which places you in the
category of [moderate or high] risk.
Ask permission to continue discussion about alcohol:
• “Would you mind if we spent just a few more minutes
talking about your use of alcohol?”
Explore member concerns, understand what they know:
• “As I mentioned, your score was [#]…on a scale
•
•
•
of 0-40 which places you in the category of [Low,
Moderate, or High] risk.”
“What do you make of your score?”
"What do you already know about how alcohol affects
your health?"
"What have you heard about what 'healthy' drinking
is?"
Alcohol Education
• •“Unhealthy alcohol use can put you at risk for injury,
•accidents,
AUDIT-C
feedback
andscore
health
problems such as diabetes,
•cancer,
Normative
feedback
insomnia, high blood pressure, stroke, heart
• Simple Advice
and gastrointestinal problem, depression and other
• Alcohol education
conditions.”
• “Would you be interested in knowing what the US
guidelines are for low-risk drinking?”
•
“The U.S. recommended guidelines for low-risk drinking for
women and adults over the age of 65 is no more than 1
drink per day (or 7 drinks per week) and for men no more
than 2 drinks per day (or 14 drinks per week).
AFFIRM, REFLECT BACK, SUMMARIZE
(“Does that sound right to you?”)
Explore Importance/Confidence (readiness to change):
• “On a scale of 1-10, where 1 is ‘not at all important’ and
10 is ‘very important’, how important is it to you to …
(e.g., change your drinking, cut back)?”
• “Why did you give it that number and not a lower
number?”
• “What would it take to raise that number?”
• “On a scale of 1-10, where 1 is ‘not at all confident’ and
10 is ‘very confident’, how confident are you that you
could make this change successfully?”
• “Why did you give it that number and not a lower
number?”
• “What would it take to raise that number?”
AFFIRM, REFLECT BACK, SUMMARIZE
(“Does that sound right to you?”)
Explore Goals and Summarize:
• “Where does this leave you? Do you want to quit, cut
down, make no change?
• “Would you like some suggestions on how to do this?”
(e.g., cut back, abstain, limit to no more than 1 drink per
day, alternate with healthier non-alcoholic beverage or
replace with activity like walking).
• What other changes do you want to make [e.g., not drink
and drive, seek help]?
• “What is your next step? How will you do that? Who will
you ask to help you? What might get in the way? How
will you deal with those challenges?”
AFFIRM, REFLECT BACK, SUMMARIZE
(“Does that sound about right?”)
Provide Alcohol Educational Materials
• "Could I send you some information about healthy
drinking?"
If yes, offer to email booklets and links to websites:
•
•
Normative Feedback
•
Explore Ambivalence (Pros and Cons):
• “What do you like about drinking?”
• “What do you like less about drinking?”
• “Okay, so on the one hand…..but on the other hand…”
“Most people, about 72% of adults in the U.S. never exceed
these daily or weekly limits.”
Simple Advice
• “Reducing your alcohol consumption to safer drinking
levels can decrease your risk.”
CONTINUE TO NEXT PAGE
•
•
Rethinking Drinking booklet
http://pubs.niaaa.nih.gov/publications/RethinkingDrinking
/Rethinking_Drinking.pdf
Rethinking Drinking: Alcohol and Your Health website
http://rethinkingdrinking.niaaa.nih.gov/; and
“Tips for Cutting Down on Drinking” booklet
http://pubs.niaaa.nih.gov/publications/Tips/tips.pdf
EAP/BH website and other materials as appropriate: (e.g.,
Mixing Alcohol and Medication; Alcohol and Women;
Young Teens and Drining; Alcohol and Older Adults;
Prevention for Children)
Close Alcohol SBI on Good Terms
SUMMARIZE member’s statements in favor of change,
emphasize strengths, and agreed on next steps.
Say “Thank You”
• “Thank you for taking a few minutes to talk with me
about your alcohol use. I appreciate your openness and
sharing your experiences/thoughts with me today.”
Document “BI provided” or “BI refused”
Document “alcohol education materials provided”
Ask Permission for Follow-up
•
"I would like to see how things are going for you over
the next few months. Would you mind if I followed up
with you? Is it okay to call your [cell phone]?"
Document “Agreed to follow-up” or “Refused follow-up”
Set Follow-up appointment
Provide Referral
[Note: More MI language can be crafted to facilitate
connection to provider and/or engagement/retention]
Moderate Risk Cases (as appropriate)
Offer referral to provider for alcohol use – e.g., affiliate
provider, community resource (AA)
•
•
"Based on the information you provided, I would
encourage you to consider bringing up your alcohol
use with your counselor at your next appointment.
What do you think about this? Do you have any
thoughts or concerns?”
High Risk Cases: Referral to Specialist for Diagnostic
Assessment – e.g., addiction specialist, alcohol disease
management, behavioral health provider or program,
community resource (AA)
•
•
"Based on the information you provided, I would
encourage you to consider getting additional help for
dealing with issues related to alcohol. I would like to
refer you/put you in touch with a provider on your
health plan.
What do you think about this? Do you have any
thoughts or concerns?”
Document Referral
STOP alcohol BI, continue EAP intake