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Cell Division Mitosis and Meiosis Why Do Cells Divide? Regrowth- Cells continue to divide to help an organism or part of an organism grow Repair- Some tissues must be repaired often such as the lining of gut, white blood cells, skin cells with a short lifespan, and cuts, scrapes or burns of the skin. Reproduction- Reproduction of the species How do you become a multicellular organism if you started out as just ONE cell? Cell Division Cells multiply by dividing! Cell Division… Through cell division, a single cell becomes two cells. Those two cells divide into four…. The beginning of the cell cycle… A cell grows To full size Produces structures it needs The cell then prepares for division Cells make a copy of DNA in the nucleus (called replication) At the end of replication, the cell has two sets of DNA that are identical The nucleus of the cell divides into two cells (daughter cells) A process called mitosis Cell Cycle The Cell Cycle in Words (copy this!) Interphase Cytokinesis Cell grows, makes a copy of DNA. Cell membrane pinches in two; each daughter cell has same number of identical chromosomes. Prophase The Cell Cycle Telophase Chromosomes stretch out; new nuclear envelope forms around chromosomes. Chromosomes and spindle fibers form; nuclear envelope breaks down. Metaphase Anaphase Centromeres split; chromatids separate and move to opposite ends. Chromosomes line up across the center and attach to a spindle fiber. Length of the Cell Cycle The 5 steps of Mitosis… Step 1: InterphaseChromosomes are copied (# doubles) Chromosomes appear as threadlike coils (chromatin) at the start, but each chromosome and its copy (sister chromosome) change to sister chromatids at end of this phase The 5 steps of Mitosis… Step 2: Prophase Mitosis begins ( cell begins to divide) Centrioles (or poles) appear and begin to move to opposite ends of cell Spindle fibers form between the poles The 5 steps of Mitosis… Step 3 Metaphase: Chromatids (or pairs of chromosomes) attach to the spindle fibers The 5 steps of Mitosis… Step 4 Anaphase Chromatids (or pairs of chromosomes) separate and begin to move to opposite ends of the cell The 5 steps of Mitosis… Step 5-Telophase: Two new nuclei form Chromosomes appear as chromatin (threads rather than rods) Mitosis ends Cytokinesis At the end of mitosis Cell membrane moves inward to create two daughter cells-each with its own nucleus with identical chromosomes Mitosis One More Look at Mitosis Watch the following clip for more information on cells Video Clip (stop clip at definition of Mitosis) Meiosis The process by which the number of chromosomes is reduced by half to form sex cells (sperms and eggs) Chromosome pairs separate and are distributed to two different cells. The resulting sex cells have only half as many chromosomes as the other cells in the organism. Meiosis Requires two divisions of the nucleus Meiosis I- (Just like mitosis) Meiosis II- two daughter cells go through a second division of the nucleus. (during this process, there is no chromosome replication) Meiosis II (after Meiosis I which is Mitosis) Meiosis II (after Mitosis or Meiosis I) Mitosis and Meiosis Mitosis Meiosis •One division of the nucleus = 2 cells •Two divisions of the nucleus = 4 cells (sex cells) •Used for sexual reproduction •Used for growth and repair •Before Meiosis begins, Mitosis must first take place (known as Meiosis I) Summary: Summary: Drawing: Drawing: ** Copy into spiral notebook (new page) and complete! ** Acrostic Poem Choose “mitosis” or “meiosis” Create an acrostic poem Create an illustration that shows the science concept using at least 4 colors Write 3 to 5 sentences explaining how the horizontal words and terms AND the illustration represent the vertical word Cancer is Uncontrolled Mitosis: •Mitosis must be controlled, otherwise growth will occur without limit (cancer) •Mutations in control proteins can cause cancer Cancer Cells Cancer is a disease in which cells grow and divide uncontrollably, damaging the parts of the body around them. Cancer cells are held together. Mutations A mutation (from Latin word that means change) is any change in a gene or chromosome. Can cause a cell to produce an incorrect protein during protein synthesis. As a result, the organism’s trait, or phenotype, may be different from what it normally would have been. Results of Mutations If a mutation occurs in a sex cell, the mutation can be passed on to an offspring and affect the offspring’s phenotype. If a mutation occurs in a body cell, the mutation will not be passed on to the organism’s offspring. Effects of mutations Introduce change in an organism (genetic variation) Can be harmful (reduces the organism’s chance for survival and reproduction) Can be helpful (improve an organism’s chance of survival and reproduction) Antibiotic resistance in bacteria Can be neither harmful nor helpful