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The Digestive System Digestive System Alimentary canal Accessory digestive organs 6 essential activities Regulation (mechanical and chemical stimuli) Extrinsic control Intrinsic control Histology of the Alimentary Canal Mucosa 3 functions Consists of three layers: a lining epithelium, lamina propria, and muscularis mucosae The mucus secretions Functions Cells Mucosa: Lamina Propria and Muscularis Mucosae Lamina Propria Muscularis mucosae Other layers Submucosa Muscularis externa Serosa Mouth Oral or buccal cavity Epithelium characteristic Salivary Glands 4 functions 3 (pair) Extrinsic salivary glands Intrinsic salivary glands Digestive Processes in the Mouth Pharynx Food and fluids to the esophagus Cells Esophagus Muscular tube, Muscularis changes enroute Stomach chyme Regions Nerve supply Blood supply Muscles of stomach Microscopic Anatomy of the Stomach Epithelial lining Gastric pits Glands of the Stomach Fundus and Body Gastric glands Parietal Mucous neck cells Chief cells Enteroendocrine cells – secrete gastrin, histamine, endorphins, serotonin, cholecystokinin (CCK), and somatostatin into the lamina propria Small Intestine: Microscopic Anatomy Structural modifications: Plicae circulares Villi Microvilli Cells and structures Liver Cells Functions Hepatic Artery and Hepatic Portal Vein The Gallbladder Bile Function of gallbladder Bile Function of bile Gallstones bile salts, bile pigments, cholesterol, neutral fats, phospholipids, and electrolytes Regulation of Bile Release Pancreas Endocrine function Islets of Langerhans Exocrine function Acini Cells Pancreatic Juice and enzymes Regulation of Pancreatic Secretion Large Intestine Cells Functions Bacterial Flora Digestive phases: Overlapping Cephalic Gastric Intestinal Nutrition Nutrients Minerals Vitamins