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Mitosis POGIL Notes 1. Phases of mitosis: Prophase, metaphase, anaphase, and telophase (PMAT) 2. Mitosis occurs before cytokinesis and after G2 (interphase) 3. The phases in interphase are G1, S, and G2 4. a. There is only one cell at the beginning of mitosis b. There are 2 cells present after mitosis 5. a. I – this is a single chromosome b. X – Replicated chromosome c. 2 chromatids in each replicated chromosome 6. In the original cell shown in model 1 during prophase, there are 4 replicated chromosome 7. There are 4 single chromosome in each new cell of telophase 8. A chromosome is consisted of DNA, which contains genes. Chromosome is important because chromosome contains trait information. 9. a. If you don’t have replication of chromosomes before cytokinesis, then both new cells may have some of the chromosomes or may not contain any at all. b. If a complete set of chromosomes had been divided into 2 separate cells, then the new cells would not be viable. The reason for this is because not all chromosomes are present to have a proper functioning cell. 10. The cells need to make more DNA during synthesis of the cell cycle because the new cells (daughter cells) need to have the same amount of DNA 11. Chromosomes are replicated during the S phase (synthesis) 12. a. Prophase is when the spindle fibers form b. The replicated chromosome separates in anaphase c. Telophase is where the spindle fibers disappear d. The purpose of spindle fibers during metaphase and anaphase is to separate the chromosome Mitosis POGIL Notes 13. a. The nuclear membrane disappeared (dissolved) after prophase b. It is necessary for the nuclear membrane to dissolve because the chromosome can be separated c. The nuclear membrane is formed during telophase 14. In cytokinesis the cytoplasm is being divided 15. Mitosis has to come before cytokinesis because the chromosomes need to be separated. 16. The DNA needs to be coiled so that DNA does not get tangled before the cell undergoes cell division. 17. Prophase the nuclear membrane dissolves and chromosomes become condense and spindle fibers are formed Metaphase Chromosomes line up at the equator Anaphase Chromosomes are being pulled apart by spindle fibers Telophase -‐Chromosomes settle at opposite poles -‐nuclear membrane forms Cytokinesis The cytoplasm splits forming 2 new daughter cells 18. If cytokinesis did not occur, then the cells will look like a peanut with 2 nuclei 19. If you skinned your knees, cells will start to undergo mitosis to make new cells to replace the damaged cells. During a growing plant the cells will be multiplying so that the plant can get bigger 20. If the sister chromatids did not line up correctly at the equator, then there will not be an equal amount of chromosomes in each daughter cell.