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Parathyroid Hormone Christina Chan Gland and Chemical Class • Parathyroid Gland • Polypeptide Target Tissue and Source of Control • bones and kidneys • CHIEF CELLS produce PTH • function: control concentration of calcium in blood When Calcium concentration falls below normal... 1. chief cells secrete PTH 2. release of stored calcium from bone 3. enhanced reabsorption of calcium in kidneys 4. stimulation of calcitriol production at kidneys Hyper/Hypo-Secretion • Hyperparathyroidism: PT gland produces too much PTH due to a tumor on PT gland • Hypoparathyroidism: when PT gland produces too little PTH Bibliography • Bowen, R. "Parathyroid Hormone." Colorado State University. N.p., 28 Sept. 2003. Web. 11 Feb. 2014. <http://arbl.cvmbs.colostate.edu/hbooks/pathphys/endocrine/thyroid/pth.html>. • "Endocrine Hormones and Disorders." Union County College. N.p., 10 Feb. 2014. Web. 11 Feb. 2014. <http://faculty.ucc.edu/biology-potter/Endocrine%20hormones%20and%20disorders.htm>. • "Normal Parathyroid Gland Function. How Parathyroid Glands Work." Parathyroid. Norman Parathyroid Center, n.d. Web. 11 Feb. 2014. <http://www.parathyroid.com/parathyroid-function.htm>. • Rennert, Nancy J., ed. "PTH." MedlinePlus. A.D.A.M, 11 Dec. 2011. Web. 11 Feb. 2014. <http://www.nlm.nih.gov/medlineplus/ency/article/003690.htm>. • Thompson, E. Gregory. "Parathyroid Hormone." Web MD. Healthwise, 10 Apr. 2010. Web. 11 Feb. 2014. <http://www.webmd.com/a-to-z-guides/parathyroid-hormone>.