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5/3 Warm-Up Study quietly for the Nature of Science (N2) and History of Genetics (N31) quiz. HW: DNA Structure Skill Check on 5/5 1 7 6 5 4 3 2 1 9 8 What does the word replication mean to you? When does replication occur in eukaryotic cells? During the S phase of Interphase. Let’s see replication in action… Enzyme adenine cytosin e thymine guanine Let’s see replication in action… Enzyme adenine cytosin e thymine guanine Let’s see replication in action… Enzym e adenine thymine cytosin e guanine What do we notice? They are the EXACT SAME! Why is this important? Allows for the continuation of the genetic information in new cells made through mitosis. adenine thymin cytosine guanin Fill in your foldable to demonstrate replication. Why do cells divide? 1. To make 2. To make old/dead 3. To make new cells during growth. new cells to replace or repair cells. specialized cells (development) This occurs through mitosis and produces body (somatic) cells. Would cells need to divide for any other reason? Would cells need to divide for any other reason? YES! In order for the organism to reproduce. How does this happen? A type of cell division known as meiosis. What is meiosis? Meiosis is a type of cell division that occurs only in reproductive organs to make gametes (sex cells). At the end of the process, four daughter cells are produced with half of the DNA of the parent cells. Male gametes are sperm/pollen and Females produce eggs. 8 chromosomes (duplicated ) 4 chromosomes in 4 daughter cells Homologous pairs line up in the middle How many chromosomes do sex cells contain? Sex cells contain half the number of the organism’s normal number of chromosomes. That means that each human gamete contains 23 chromosomes. Why is it essential for meiosis to result in half the total number of chromosomes? Why is it essential for meiosis to result in half the total number of chromosomes? During fertilization, the two sex cells combine and the original number of chromosomes is restored. Human egg cell 23 chromosome s Human zygote 46 ch. Human sperm cell 23 chromosomes Mitosis 2 cell s 4 cell s 8 cell s So how can scientists predict offspring? Punnett Squares Parent How do I set up a Genotype Punnett square? Tt In order to set up a Punnett square, you must first understand that parents can give only one allele for a trait during meiosis. Let’s look at plant height in pea plants to demonstrate: T DNA is copied T t Parent DNA X T T T t t X t t Since 2 of the 4 resulting daughter cells have the same DNA, we only use 2 of the possible daughter cells in setting up our Punnett square. How do I set up a Punnett Parent One square? Parent Genotypes: Tt X Tt T t X t t T T T T X t t How do I set up a Punnett Parent Two square? Parent Genotypes: Tt X Tt T t T t t T T T X X T t t t How do I set up a Punnett square? TT tt TT T T T t T t t t tt Parent Genotypes: Tt X Tt How do I set up a Punnett square? T t T T T T t Genotypic Ratio: always written as purebred dominant : hybrid : purebred recessive and reduce if needed 1 TT : 2 Tt : 1 tt t T t t t Parent Genotypes: Tt X Tt How do I set up a Punnett square? T t T T T Tall T t Tall Phenotypic Ratio: always written as dominant : recessive and reduce if needed 3 Tall : 1 short t T t Tall t t Short Parent Genotypes: Tt X Tt