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病原生物学
Medical Microbiology and Parasitology
Part I: Medical Microbiology
Part II: Medical Parasitology
Medical Microbiology
Xiao-Kui GUO(郭晓奎）
Dept. of medical Microbiology and Parasitology
E.mail: [email protected]
Tel: 776712
Office: 5-511
Introduction
Microorganisms(Microbes)
Microbiology
Medical Microbiology
What is Microorganisms
 Microorganisms are creatures that are not
directly visible to the unaided eye, with
dramatical biologic diversity.
 Viruses , bacteria, fungi, protozoa and some
algae are all in this category
 All with the exception of plants and animals
Distribution of microorganisms
 Air
 Soil
 Water
 Animals
 Human body
100m
300m
1400m
2100m
3150m
4050m
6000m
Microorganisms and Human Beings
 Beneficial activities: Most microbes are of
benefit to human beings, some are
necessary( nitrogen, carbon cycles, etc)
 Harmful activities: A portion of microbes
cause diseases and are poisonous to human,
and these are really that concern us in the
study of medical microbiology, etc.
Microbiology
 Microbiology is the biology of
microorganisms. It is a bioscience for the
study of the evolution, Classification ,
morphology, physiology, genetics, ecology
of microbes under certain definite
conditions, The law of their life activities,
and their interaction with human being,
animals or plants as well as with natural
environment.
The Importance of Microbiology
 Environment
 Medicine
 Food
 Industry
 Biotechnology
 Research
History of Microbiology
 Experience phase经验时期
 Experimental phase实验时期
 Modern phase现代微生物学时期
Experience phase
Experimental phase
 Leeuwenhoek
 Pastur
 Koch
 Lister
Koch’s postulates
 The microbe must be found in the body in all
cases of the disease
 It must be isolated from a case and grown in a
series of pure culture in vitro
 It reproduce the disease on the inoculation of a
late pure culture into a susceptible animal
 The microbe must be isolated again into pure
culture from such experimentally caused
infection.
艾利希，1910
Modern phase
Fei-Fan Tang
Emerging and
Reemerging
Infectious Disease
 AIDS
 Tuberculosis
 Hepatitis
 Gastric ulcer
 SRAS
Medical Microbiology
 The medical microbiology is one of the essential
basic sciences for medine. It is the study of
Biological characteristics of microorganisms and
their relationships with human hosts
 Medical Bacteriology
 Medical Viriology
 Medical Mycology
 Parasitology
 Immunology
Purpose for learning of Medical Microbiology
Textbook
 Medical Microbiology
http://basic.shsmu.edu.cn/passw/micro2/index.asp