Download A comparison of overall health between Asian

In the name of God
A comparison of overall health between
Asian and Australians from European
background:
A west Australian study of Diet &
Metabolic Syndrome Risk Factors
Majid Meshkini
Supervisor: Dr Jaya Earnest
Context of the researcher
Selected
• Graduated as Doctor of Medicine (MD) from
IUMS, 1996, Tehran, Iran
• As a medical doctor (GP), 1996-2006
• Co-ordinator of urban physicians, savojbolaq city
• Head of Health Centre, Shahriar city
• As a manager in medical education field, MoHME
• As a manager in health affairs, MoHME
• Technical advisor for health sector of MoHME
Introduction
• The Trend of Diseases:
Communicable
Non-Communicable
• Non-Communicable Diseases: (CVD & Diabetes)
• Burden Overall:
– 35 million deaths annually: 60% of all deaths, over the World (WHO, 2006)
• Prevalence of some Important Diseases & risk factors:
– Over weight & Obesity, 1.6 Billion adults (WHO, 200)
– Diabetes, 300 million in 2025, (WHO, 200)
Different definition of the MetS
• World Health Organization (WHO), 1999
• European Group for the Study of Insulin
Resistance (EGIR), 1999
• Adult Treatment Panel III, model (ATPIII), 2001
• International Diabetes Federation (IDF), 2005
Ethnicity effects on MetS
• Genetic and metabolic syndrome
– Genetics is a powerful factor in the incidence of
MetS’ components
– Affects among of both different countries &
various ethnic group on a society
• Impact of ethnicity on MetS components
– Comparison between African population &
Caucasians
– Comparison between Caucasians & South Asians
Prevalence of The MetS in some
countries & region
Australia
30.7 %
China
46.3%
India
31.6%
Iran
26.4%
South Asia
10-30 %
Gaps
• Lake of a basic study in Australia focused on
ethnicity effect on the MetS
• Comparison the correlation between ethnicity &
MetS’ component such as, dyslipidemia and
endothelial dysfunction
• Lake of statistics regarding to the Middle East
Objectives
• To investigate the effects of ethnicity on the
metabolic syndrome risk factors in overweight
and obese subjects
• To explore the relationship between other
relative components in metabolic syndrome
and different ethnic groups
Study plan & methodology
• Cross sectional design
5 Ethnic group X 30 / group = 150 participants
• Measurements
– Anthropometrical
– Physical
– Biochemical, by blood sampling
– Food records, using a questionnaire
Five Ethnic Group
• Australian from European background
• Chinese
• Iranian/ Afghani
• Iraqi/ Arabian
• South Asian, (Indian, Bangladeshi, Sri Lanka)
Measurements
will be undertaken at the Curtin University, Centre for International Health
and by questionnaire
• Anthropometrical:
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–
–
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Height
Weight
BMI, Body Mass Index
Waist circumference
• Biophysical:
– BP
– Endothelial Dysfunction
– Fat Distribution
• Food intake
– Total intake energy
– Macro nutrients
• Carbohydrate,
• Protein &
• Fat
– Fibres
• Fruits & vegetables
– Food items
Measurements
Continue
Will be done in the laboratory of the School of Biomedical Science
• Biochemical:
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–
–
–
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FBG (Fasting Blood Glucose)
Serum lipid (Including Triglyceride & Cholesterol)
Insulin
CRP (C-Reactive Protein)
PAI, (Plasminogen Activator Inhibitor)
– Adinopectin
Significance
• Efforts to achieving an acceptable definition
for MetS, specified for Ethnic differences
• Reliable criteria for relative diseases diagnosis
• Multicultural foundation countries, Particularly
Australia
Some analysis that I hope to
undertake
• Comparison the metabolic syndrome
among the different ethnic groups
• Evaluate the correlation between Ethnicity
& CRP among of metabolic syndrome
• Explore the relationship between
Endothelial Dysfunction and Ethnicity
• Is there an association between food
intake & ethnicity