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Regulating the Cell Cycle
Chapter 10-3
Controls on Cell Division
• When there is an injury
such as a cut in the skin
or break in a bone,
• the cells at the edge of
the injury are stimulated
to divide rapidly.
Controls on Cell Division
• When the healing process
nears completion,
• The rate of cell division
slows down, controls on
growth are restored, and
every thing returns to
normal.
Cell Cycle Regulators
Cyclins regulate the timing
of the cell cycle in the
eukaryotic cells.
Cell Cycle Regulators
• Internal regulators
• they are proteins that
respond to events inside
the cell.
Cell Cycle Regulators
• External regulators:
• Direct cells to speed up or slow
down the cell cycle.
• They include growth factors
• They prevent excessive cell
growth and keep the tissues of
the body from disrupting each
other.
Uncontrolled Growth
• Cancer is a disorder in
which some of the body’s
cells lose the ability to
control growth.
• Uncontrolled growth of
cells in the body.
Uncontrolled Growth
• Cancer cells don’t respond to signals
that regulate growth.
• Cancer cells form masses of cells
called tumors.
• Cancer cells break loose and spread
throughout the body.
Uncontrolled Cell Growth
• Cancer is a disease of the
cell cycle.