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Chiropractic And Pain
Stephen M. Perle, D.C., M.S.
Professor Of Clinical Sciences
University Of Bridgeport
College Of Chiropractic
What Experiences Do You Have
About Chiropractic?
Your impression?
Précis
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History of chiropractic
What is chiropractic care?
Systematic reviews on clinical
effectiveness
Research on mechanism of spinal
manipulation
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History Of Chiropractic
The MTV Version
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What is chiropractic?
Anachronistic Chiropractic Theory
Bone Out Of Place
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Nonsurgical Spine Specialist
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Primary intervention
is spinal manipulation
Spinal rehabilitation/
stabilization exercises
Physiological
therapeutics
Soft tissue
mobilization
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Levels Of Evidence:
Not All Hands Are Of Equal Value
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Mechanical Neck Pain
C S Headache
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Neither SMT nor mobilization (MOB) were
effective alone or in combination with PT
SMT or MOB with exercise is effective
Gross AR, Hoving JL, Haines TA, Goldsmith CH, Kay T, Aker P, et
al. A Cochrane review of manipulation and mobilization for
mechanical neck disorders. Spine. 2004 Jul 15;29(14):1541-8.
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Neck Pain
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Bone and Joint Decade 2000-2010 Task Force on Neck Pain and Its
Associated Disorders
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359 invasive and noninvasive intervention articles deemed relevant
170 (47%) were accepted as scientifically admissible
139 of these related to noninvasive interventions
Manipulation or mobilization effective for
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WAD
Neck pain
Hurwitz EL, Carragee EJ, van der Velde G, Carroll LJ, Nordin M, Guzman J,
et al. Treatment of neck pain: noninvasive interventions: results of the Bone
and Joint Decade 2000-2010 Task Force on Neck Pain and Its Associated
Disorders. Spine. 2008 Feb 15;33(4 Suppl):S123-52.
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Chronic/Recurrent Headache
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Prophylactic treatment of chronic tension-type headache
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Prophylactic treatment of migraine headache
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Amitriptyline more effective than SMT during treatment
SMT is superior in short term after cessation of both treatments
SMT may be an effective treatment option short-term effect
similar to amitriptyline
Episodic tension-type headache
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Adding SMT to massage is not effective
Bronfort G, Nilsson N, Haas M, Evans R, goldsmith C, Assendelft W, et al.
Non-invasive physical treatments for chronic/recurrent headache. Cochrane
database Syst rev. 2004;3:cd001878
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Chronic/Recurrent Headache
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Prophylactic treatment of cervicogenic headache
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SMT is effective in the short and long term when
compared to
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No treatment
Massage or placebo SMT
Post-traumatic headache
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MOB is more effective in the short term than cold
packs
Bronfort G, Nilsson N, Haas M, Evans R, goldsmith C, Assendelft W,
et al. Non-invasive physical treatments for chronic/recurrent
headache. Cochrane database Syst rev. 2004;3:cd001878
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Carpal Tunnel Syndrome
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Carpal bone MOB significantly improved
symptoms after three weeks
However, only one study
O'Connor D, Marshall S, Massy-Westropp Non-surgical
treatment (other than steroid injection) for carpal tunnel
syndrome. Cochrane Database Syst Rev.
2003;(1):CD003219.
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Low Back Pain
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31 studies – 5,202 participants met inclusion criteria
Acute LBP
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Moderate evidence that SMT provides more short-term pain relief than MOB and
detuned diathermy, and limited evidence of faster recovery than a commonly
used PT
Chronic LBP
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Moderate evidence that SMT has an effect similar NSAID
SMT/MOB is effective in the short term when compared with placebo and GP
care, and in the long term compared to physical therapy
Limited to moderate evidence that SMT is better than physical therapy and home
back exercise in both the short and long term.
Bronfort G, Haas M, Evans RL, Bouter LM. Efficacy of spinal manipulation
and mobilization for low back pain and neck pain: a systematic review and
best evidence synthesis. Spine J. 2004 May-Jun;4(3):335-56.
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New Review on Chronic LBP
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Preponderance of the evidence for efficacy &
estimated very low risk of serious adverse
events support SMT & MOB as viable options for
treatment of CLBP
SMT and MOB at least as effective as other
efficacious & commonly used interventions
Bronfort G, Haas M, Evans R, Kawchuk G, Dagenais S. Evidenceinformed management of chronic low back pain with spinal
manipulation and mobilization. Spine J. 2008 Jan-Feb;8(1):213-25.
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Nocturnal Enuresis
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Weak evidence supports the use of chiropractic
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Single small trial (31 treatment & 15 control group)
Better than sham manipulation
Glazener CM, Evans JH, Cheuk DK. Complementary and
miscellaneous interventions for nocturnal enuresis in children.
Cochrane Database Syst Rev. 2005(2):CD005230.
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Primary Or Secondary Dysmenorrhea
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No evidence of effectiveness of SMT
More research needed
Proctor ML, Hing W, Johnson TC, Murphy PA. Spinal
manipulation for primary and secondary dysmenorrhoea.
Cochrane Database Syst Rev. 2001(4):CD002119.
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Asthma
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No evidence of effectiveness of SMT
More research needed
Current RCT in Australia n=1000
Hondras MA, Linde K, Jones AP. Manual therapy for
asthma. Cochrane Database Syst Rev.
2005(2):CD001002.
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Science Of Spinal Manipulation
Interarticular Adhesions
Rat Joint Dysfunction (Subluxation) Model
Cramer GD, Fournier JT, Henderson CN,
Wolcott CC. Degenerative changes
following spinal fixation in a small animal
model. J Manipulative Physiol Ther
2004;27(3):141-54.
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Manipulation Breaks Adhesions
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Manipulation may increase flexibility of a
motion segment
Single case with sophisticated assessment
of motion segment stiffness
Kawchuk G, Herzog W. Preliminary evidence of changes in tissue
stiffness following spinal manipulation. In: International Conference
on Spinal Manipulation; 1996: FCER; 1996. p. 18.
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Manipulation Breaks Adhesions
Manipulation gaps the Z-joint
Cramer GD, Gregerson DM, Knudsen JT, Hubbard BB, Ustas LM,
Cantu JA. The effects of side-posture positioning and spinal
adjusting on the lumbar Z joints: a randomized controlled trial with
sixty-four subjects. Spine 2002;27(22):2459-66.
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Altered Muscle Firing Pattern
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Transversus abdominis activated (diaphragm & pelvic mm) 30 ms prior
to arm or leg movements
In LBP patients transversus abdominis activated 30 ms after arm or leg
movements
Hodges PW, Richardson CA. Delayed postural contraction of transversus abdominis in low back pain
associated with movement of the lower limb. J Spinal Disord 1998;11(1):46-56.
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Response to SMT
Pickar & Wheeler 2001, JMPT 24(1):2-11
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Muscle Spindle
Response To SMT
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GTO Response To SMT
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Manipulation Changing Muscle
Function
Brenner AK, et al. Improved activation of
lumbar multifidus following spinal
manipulation: a case report applying
rehabilitative ultrasound imaging. J Orthop
Sports Phys Ther. 2007 Oct;37(10):613-9.
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Restoration Of Firing Pattern
Gill NW, Teyhen DS, Lee IE. Improved
contraction of the transversus abdominis
immediately following spinal manipulation:
a case study using real-time ultrasound
imaging. Man Ther. 2007 Aug;12(3):280-5.
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Effects On Pain &
Pain Processing
Manipulation’s Effects On CNS In
Pain Modulation
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Manipulation of the knee resulted in
analgesia of induced hyperalgesia of the
paw of a rat
Used selective neurotransmitter blocks
Manipulation activates descending
inhibitory pathways using serotonin and
noradrenaline
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Suggested Analgesic Mechanism
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Authors suggest that manipulation stimulates
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Lateral periaquaductal gray (PAG)
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Rostral Ventral Medulla (RVM)
Dorsolateral pons
Part of the descending analgesia system
Skyba DA et al. Joint manipulation reduces hyperalgesia by
activation of monoamine receptors but not opioid or GABA
receptors in the spinal cord. Pain. 2003 Nov;106(1-2):159-68.
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Stroke & Cervical Manipulation
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Small risk of stroke following chiropractic visits
Risk of stroke after chiropractic visit = risk of
stroke after medical visit
People with prodrome of stroke seek care
Cassidy JD, et al. Risk of vertebrobasilar stroke and
chiropractic care: results of a population-based case-control
and case-crossover study. Spine. 2008 Feb 15;33(4
Suppl):S176-83.
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What questions do you have?