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East Midlands Cancer Drug Fund (EMCDF) Application for Peptide Receptor Radionuclide Therapy (i.e. Lutetium177 Octreotate or Yttrium90 octreotide/octreotate for Progressive Symptomatic Inoperable well-differentiated Neuro-endocrine Tumours PATIENT PERSONAL DETAILS Patient Name: Date of Birth: NHS Number: Primary Care Trust: GP Name & Practice Details: Please note that all personal information will be removed prior to the consideration by the EMCDF panel DETAILS OF REQUESTER (include referring clinician contact details in the event of query or need for clarification) Name: Designation: Trust: Contact phone number: Secure email for correspondence: Provider Trust Chemotherapy Lead Yes No (or equivalent) Support: Name of Trust Chemotherapy Lead (or equivalent): CLINICAL DETAILS ECOG Performance status Histologically confirmed well differentiated NET Octreotide scintigraphy or Gallium-68 Octreotate PET scan at least as high as that in normal liver tissue Treatment with PRRT has been documented at a dedicated neuroendocrine MDT This patient’s treatment will be managed under the supervision of a clinician competent in the use of radionuclide agents as anti-cancer therapy. Pancreatic NET Progressed or symptoms not controlled, despite or not suitable for other systemic therapy. Other NET Progressed or symptoms not controlled following prior somatostatin analogue therapy 0 2 Yes Yes 1 3 No No Yes No Yes No Yes No Yes No CONSENT I confirm that this Request has been discussed in full with the patient and that the patient is aware that they are consenting for the Cancer Drugs Fund Panel to access confidential clinical information held by clinical staff involved with their care about them as a patient to enable full consideration of this funding request Signature of Requester: Date: MONITORING RESPONSE How will the benefits of the procedure/treatment be measured? (incl. frequency of assessments) What ‘stopping’ criteria will be in place to decide when the treatment is ineffective? 1. Clinical and radiological evidence of progression 2. Drug toxicity Please note that regular updates on response to treatment may be requested by the Cancer Drugs Fund Panel and/or EMSCG E-mail completed application forms to [email protected] Document Code: EMCN-DC-0177-12 Written By: Colin Ward Date of Issue: 6th December 2012 Authorised By: CDAG Review Date: December 2014 Page Number: 1 of 1