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Bell Ringer
1. Why do cells need to divide in multicellular
organisms?
2. What is the difference between prokaryotes and
eukaryotes with regard to chromosomes?
3. What does a human chromosome consist of?
Draw one! Label.
4. Describe a role of chromatin in chromosome in
your own words.
DNA and Chromosomes
Chromatin
DN
A
The function of
chromatin is to
efficiently
package DNA
Histones
Cell Cycle
Cell Cycle is a sequence of events through
which a cell progresses during its lifetime
• Cell can be either in dividing (Mitotic
Phase) or non-dividing state (Interphase)
Interphase
about 90% of the cell cycle
G1 Phase (Gap 1):
•
•
•
•
Cell Growth
Protein Synthesis
Cell Metabolism
Preparation for S Phase
S Phase (synthesis):
– DNA is replicated
G2 Phase (Gap 2):
• Further Cell Growth
• Protein Synthesis
• Specialized
proteins needed for Cell Division
The cell grows during all three
phases, but chromosomes are
duplicated only during the S phase
Mitotic Phase
Mitosis:
•
•
•
•
Prophase
Metaphase
Anaphase
Telophase
Cytokinesis
is division of cytoplasm/cell:
– cleavage furrow forms in animal cells
– cell plate (cell wall) forms in plant cells
– daughter cells are identical
Figure 12.10a
(a) Cleavage of an animal cell (SEM)
Cleavage furrow
Contractile ring of
microfilaments
100 m
Daughter cells
Figure 12.10b
(b) Cell plate formation in a plant cell (TEM)
Vesicles Wall of parent cell
forming
cell plate
Cell plate
1 m
New cell wall
Daughter cells
Cell Cycle
• Interphase
• Prophase
• Metaphase
• Anaphase
• Telophase & Cytokinesis
Interphase
Animal Cell
Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Plant Cell
Prophase
Animal Cell
Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Plant Cell
Prophase
The cell prepares for nuclear division
• Animal and Plant Cell
– Packages DNA into
chromosomes
– nuclear envelope
breaks down
– Centrosomes move
apart and forms
spindle which guides
chr. separation
Metaphase
Animal Cell
Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Plant Cell
Metaphase
The cell prepares chromosomes for division
• Animal and Plant Cell
– Chromosomes line up at
the center of the cell
– Spindle fibers attach
from daughter cells to
chromosomes at the
centromere
Anaphase
Animal Cell
Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Plant Cell
Anaphase
The chromosomes divide
• Animal and Animal Cell
– Spindle fibers pull
chromosomes apart
– ½ of each chromosome
(called chromotid)
moves to each daughter
cell
Telophase
Animal Cell
Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Plant Cell
Telophase
The cytoplasm divides
• Animal Cell
–
–
–
–
–
chromosomes uncoil
2 nuclei form
spindle breaks down
nuclear envelope and
nucleoli reappear