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PowerPoint® Lecture Slides prepared by Leslie Hendon, University of Alabama, Birmingham 22 HUMAN ANATOMY PART 2 The Digestive System fifth edition MARIEB | MALLATT | WILHELM Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Histology of the Alimentary Canal Wall Same four layers from esophagus to anus The mucosa – innermost layer Consists of Epithelium Lamina propria Muscularis mucosae The submucosa – external to the mucosa Contains blood and lymphatic vessels, nerve fibers Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Histology of the Alimentary Canal Wall The muscularis externa – external to the submucosa Two layers Circular muscularis – inner layer Longitudinal muscularis – outer layer The serosa – the outermost layer Is the visceral peritoneum Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Histology of the Alimentary Canal Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.5 Smooth Muscle Primarily found in walls of viscera Fibers elongated Have one centrally-located nucleus Grouped into sheets Longitudinal layer – parallel to long axis of organ Circular layer – deeper layer, fibers run around circumference of organ Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Smooth Muscle Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.6a, b Smooth Muscle Contraction Myofilaments operate by interaction with cytoskeleton Dense bodies – correspond to Zdiscs of skeletal muscle Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.7a–c Innervation of Smooth Muscle Innervated by ANS Few fibers per sheet innervated Sheet of smooth muscle contracts as a unit Exceptions Iris of eye Arrector pili muscles in skin Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Innervation of Smooth Muscle Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.8 Nerve Plexuses Myenteric nerve plexus Lies between circular and longitudinal muscularis Controls peristalsis and segmentation Submucosal nerve plexus Lies in submucosa Signals glands to secrete Innervation Sympathetic and parasympathetic motor fibers Visceral sensory fibers Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings The Peritoneal Cavity and Peritoneum Peritoneum – a serous membrane Visceral peritoneum – surrounds digestive organs Parietal peritoneum – lines the body wall Peritoneal cavity – a slit-like potential space Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings The Peritoneal Cavity and Peritoneum Mesentery – a double layer of peritoneum Holds organs in place Sites of fat storage Provides a route for circulatory vessels and nerves Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.9a The Peritoneal Cavity and Peritoneum Retroperitoneal organs Behind the peritoneum Peritoneal organs Digestive organs that keep their mesentery Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.9b Mesenteries Superficial view of abdominal organs Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.10a Mesenteries Lesser omentum attaches to lesser curvature of stomach Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.10b Mesenteries Greater omentum – a “fatty apron” of peritoneum Greater omentum and transverse colon reflected Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.10c Mesenteries Sagittal section through the abdominopelvic cavity Mesenteries attach to posterior abdominal wall Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.10d Secondarily Retroperitoneal Organs Initially formed within peritoneum Become retroperitoneal Fuse to posterior abdominal wall Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.11 Summary of Intraperitoneal and Secondarily Retroperitoneal Organs Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Table 22.1 The Mouth and Associated Organs The mouth – oral cavity Mucosal layer Stratified squamous epithelium Lamina propria The lips and cheeks Formed from orbicularis oris and buccinator muscles, respectively Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Anatomy of the Mouth Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.12a Anatomy of the Mouth The labial frenulum Connects lips to gum The palate Forms the roof of the mouth Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.12b The Tongue Interlacing fascicles of skeletal muscle Grips food and repositions it Helps form some consonants Intrinsic muscles – within the tongue Extrinsic muscles – external to the tongue Lingual frenulum Secures tongue to floor of mouth Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings The Superior Surface of the Tongue Tongue papillae Filiform papillae – no taste buds Fungiform papillae Circumvallate papillae Sulcus terminalis Marks border between mouth and pharynx Posterior 1/3 of tongue lies in oropharynx Lined with lingual tonsil Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Superior Surface of the Tongue Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.13 The Teeth Deciduous teeth – 20 teeth First appear at 6 months of age Permanent teeth – 32 teeth Most erupt by the end of adolescence Dental formula – shorthand Way to indicate number and position of teeth 2I, 1C, 2P, 3M Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings The Teeth Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.14 Tooth Structure Longitudinal section of tooth in alveolus Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.15 The Salivary Glands Produce saliva Compound tubuloalveolar glands Parotid glands Parotid duct – parallel to zygomatic arch Contains only serous cells Submandibular glands Lies along medial surface of mandible Sublingual glands Lies in floor of oral cavity Contains primarily mucous cells Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings The Salivary Glands Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.16 The Pharynx Oropharynx and laryngopharynx Passages for air and food Lined with stratified squamous epithelium External muscle layer Consists of superior, middle, and inferior pharyngeal constrictors Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings The Esophagus Gross anatomy – muscular tube Begins as a continuation of the pharynx Joins the stomach inferior to the diaphragm Cardiac sphincter – closes lumen to prevent stomach acid from entering esophagus Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings The Esophagus Microscopic anatomy Epithelium is stratified squamous epithelium When empty – mucosa and submucosa in longitudinal folds Mucous glands – primarily compound tubuloalveolar glands Muscularis externa Skeletal muscle first third of length Adventitia – most external layer Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Microscopic Structure of the Esophagus Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.17a, b The Stomach Site where food is churned into chyme Secretion of pepsin begins protein digestion Functions under acidic conditions Food remains in stomach approximately 4 hours Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings The Stomach Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.18a The Stomach Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.18b Microscopic Anatomy of the Stomach Muscularis has three layers Circular and longitudinal layers and oblique layer Epithelium is simple columnar epithelium Mucosa dotted with gastric pits Gastric glands – deep to gastric pits Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Microscopic Anatomy of the Stomach Gastric glands of fundus and body Mucous neck cells Secrete a special mucus Parietal (oxyntic) cells Secrete hydrochloric acid and gastric intrinsic factor Chief (zymogenic) cells Secrete pepsinogen Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings The Stomach – Microscopic Anatomy Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.19a–d The Small Intestine – Gross Anatomy Longest portion of the alimentary canal Site of most enzymatic digestion and absorption Three subdivisions Duodenum Jejunum Ileum Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings The Duodenum Receives digestive enzymes and bile Main pancreatic duct and common bile duct enter duodenum Sphincters control entry of bile and pancreatic juices Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings The Duodenum and Related Organs Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.20 The Small Intestine – Microscopic Anatomy Modifications for absorption Circular folds (plicae circulares) Transverse ridges of mucosa and submucosa Villi Finger-like projections of the mucosa Covered with simple columnar epithelium Microvilli Further increase surface area for absorption Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Histology of the Intestinal Wall Absorptive cells Uptake digested nutrients Goblet cells Secrete mucus that lubricates chyme Enteroendocrine cells Secrete hormones Intestinal crypts Epithelial cells secrete intestinal juice Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings The Small Intestine – Structural Features Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 22.21a–d