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Isabel Rodriguez, CV
CURRICULUM VITAE
Isabel RODRIGUEZ ENRIQUEZ, CSIC Research Staff
Centro de Biología Molecular “Severo Ochoa”(CBM-SO)
C/ Nicolas Cabrera Nº1. Univ. Autónoma de Madrid.
Campus de Cantoblanco, 28049 Madrid, España
Tel.: 34 91 196 4693, Fax: 34 91 1964420, E-mail: [email protected]
Date of Birth: July 27, 1961
Place of Birth: Madrid (Spain).
Nationality: Spanish
EDUCATION
Chemistry School, Universidad Complutense de Madrid, Spain
Doctoral Thesis in Neurobiology: “Competence to develop sensory organs in response to the
activity of the proneural genes achaete and scute is temporal- and spatially regulated in
Drosophila”.
Centro de Biología Molecular (Prof. Dr. J. Modolell)
1992
Graduation from Science School, Univ. Autónoma de Madrid, Spain.
POSTDOCTORAL TRAINING AND EMPLOYMENT HISTORY
Research Experience
Postdoctoral fellow, Centro de Biología Molecular, Madrid, Spain.
Postdoctoral fellow, Zoology Institut, University of Zürich, Switzerland.
Postdoctoral fellow, Centro de Biología Molecular, Madrid, Spain.
2003-08
Research Associate (Programa “Ramón y Cajal”), Centro de Biología
Molecular, Madrid, Spain.
Since 9/2008 CSIC Research Staff at the Department of Developmental Biology,
Centro de Biología Molecular, Madrid, Spain.
Isabel Rodriguez, CV
Teaching Experience
Associate Professor at University Francisco de Vitoria, Madrid.
Subject: Developmental Biology. (Tutorials, lectures and practicals).
Since 2006
Associate Professor at University Francisco de Vitoria, Madrid. Subject:
Genomics. (Tutorials, lectures and practicals).
FELLOWSHIPS
1994-96
Postdoctoral Fellowship, European Molecular Biology Organisation (EMBO).
1999
Short term EMBO Felloship.
AWARDS
1993
Doctoral Thesis Awards. “Caja Madrid” Foundation
DOCTORAL THESIS SUPERVISOR
2008
Elvira Benitez. Department of Molecular Biology.
Universidad Autonoma de Madrid
STUDENT SUPERVISION
JAE Students: Jesus Garcia Salinero (JAE intro, 2008)
Juan Miguel Sánchez (JAE intro, 2008)
Adelaida Palla (Collaboration scholarship from the Ministry of Education
(2008-09)
FUNDED RESEARCH PROJECTS AS PRINCIPAL INVESTIGATOR
2005-06
“Functional analysis of the dachsous cadherin during Drosophila
development”. Funded by Comunidad Autónoma de Madrid.
GR/SAL//0150/2004. Project included fundings for a Postdoctoral
fellow: Dr. Patricia Giraldo.
.
“Functional analysis of atypical cadherins on the regulation of the main
developmental signalling pathways in Drosophila: involvement in the human usher
syndrome type 1”.
Funded by Ministerio de Educación y Ciencia. BFU2006-14010/BMC
2009
Searching for new proteins that interact with the mouse CDH23 cadherin
as potential markers for detection of the Usher’s Syndrome in humans.
Funded by CSIC and Comunidad de Madrid. CCG08-CSIC/SAL-3435
Isabel Rodriguez, CV
2008-09
Searching for new components of the mechanism of action of atypical
cadherins in Drosophila. Funded by CSIC. 200820I167.
2009-11
Genetic and molecular analysis of protocadherins during Drosophila
development: The mechanism of action. BFU2008-01869/BMC
PUBLICATIONS
I. Rodriguez, R. Hernandez, J. Modolell and M. Ruiz-Gomez
Competence to develop sensory organs is temporally and spatially regulated in
Drosophila epidermal primordial. EMBOJ 9, 3583-92 (1990) (issue cover).
IF: 12,64
Citations: 131
M.D. Martin-Bermudo, F. Gonzalez, M. Dominguez, I. Rodriguez, M. Ruiz-Gomez, S.
Romani, J. Modolell y F. Jimenez
Molecular characterization of the lethal of scute genetic function.
Development 118, 1003-12 (1993).
IF: 9,71
Citations: 19
J. L. Gómez-Skarmeta, I. Rodriguez, C. Martínez; J. Culi; D. Ferrés-Marcó; D.
Beamonte y J. Modolell.
Cis-regulation of achaete and scute shared enhancer-like elements drive their
coexpression in proneural clusters of the imaginal discs. Genes & Dev. 9, 1869-82
(1995).
IF: 19,06
Citations: 118
C. Parras; L. Garcia-Alonso; I. Rodriguez y F. Jimenez.
Control of neural precursor specification by proneural genes in the CNS of Drosophila.
EMBO J. 15, 6394-99 (1996).
IF: 13,17
Citations: 33
I. Rodriguez and K. Basler.
Control of compartmental affinity boundaries by Hedgehog.
Nature 389 (October 9): 614-618 (1997). News & Views from P. Lawrence.
IF: 28,83
Citations: 75
T. Pena-Rangel, I. Rodriguez and J. Riesgo-Escovar.
A misexpression study examining dorsal thorax formation in Drosophila melanogaster.
Genetics 160 1035-1050 (2002).
IF: 4,48
Citations: 30
F. Cavodeassi, I. Rodriguez and J. Modolell.
Dpp signalling is a key effector of the wing-body wall subdivision of the Drosophila
mesothorax. Development 129, 3815-3823(2002).
IF: 7,88
Citations: 15
I. Rodriguez
The dachsous gene, a member of the cadherin family, is required for Wg dependent
pattern formation in the Drosophila wing disc. Development 131, 3195-3206 (2004).
Isabel Rodriguez, CV
IF: 7,14
Citations: 14
LA Baena-López, I. Rodriguez* and A. Baonza*
The tumor suppressor genes, dachsous and fat, modulate different signalling pathways
by regulating dally and dally-like . *co-corresponding authors.
Proc Natl Acad Sci U S A. 105(28) 9645-9650 (2008)
I. Rodriguez, LA Baena-López and A. Baonza
Upregulation of Glypicans in Hippo mutants alters the coordinated activity of
morphogens. Fly 2:6 320-322 (2008).
E. Benítez, Sarah J. Bray, I. Rodriguez, and I. Guerrero
Lines is required for normal operation of Wingless, Hedgehog and Notch pathways during wing
development.
Development 136, 1211-1221 (2009)
PARTICIPATION IN RELEVANT MEETINGS FROM 2003
AUTHOR: I. Rodríguez
TITLE: Dachsous is required in the Wg receiving cells for wing-hinge specification.
Poster
Workshop on Wnt genes and Wnt signalling. Madrid (Spain), 2003.
AUTHOR I. Rodríguez
TITLE: Dachsous is a cadherin required for early specification along the P-D axis in the
wing disc.
Boundaries in development: 30 years of progress. Heidelberg (Germany), 2003
AUTHORS: E. Benítez, I. Rodríguez and I. Guerrero
TITLE: Role of the gene lines in the control of both, proliferation and cell fate during
Drosophila development.
III Annual Symposium “The Cell in Development”. CRG. Barcelona (Spain), 2004.
AUTHORS: I. Rodriguez and I. Guerrero
TITLE: “The Drosophila ortholog of the vertebrate TIEG mediates Dpp pathway during
development”.
XIX European Drosophila Research Conference. Eger (Hungary), 2005
AUTHOR: I. Rodriguez
TITLE: Smoothened plays a role in posterior cells during imaginal disc development.
XIX European Drosophila Research Conference. Eger (Hungary), 2005
AUTHORS: P. Giraldo e I. Rodriguez
TITLE: Función de la caderina Dachsous durante el desarrollo imaginal de Drosophila.
XXIX Congreso de la SEBBM. Elche (Spain), 2006.
AUTHOR: L.A. López-Baena, A. Baonza y I. Rodriguez
Isabel Rodriguez, CV
TITLE: dally and dally-like are two novel target genes of Dachsous and Fat during
imaginal disc development.
Joint Meeting of British & Spanish Developmental Biology Societies. Seville (Spain),
2008.
AUTHORS: J. Sierra, A. Palla, L. Varas y I. Rodríguez
TITLE: Searching for the components of Ds/Ft pathway in Drosophila and their
orthologs in Mouse.
16th Internacional Society of Developmental Biologists Congreso 2009. Edinburgh.
(Scotland)
INVITED CONFERENCES FROM 2003
TITLE: Dachsous, a Drosophila cadherin, required to modulate Wg signalling during
wing/hinge specification.
Instituto Cajal. CSIC, Madrid (Spain). 2003
TITLE: Role of Dachsous in proximo-distal patterning in the wing disc of Drosophila
Centro Andaluz de Biología del Desarrollo, CSIC. Seville (Spain). 2004
TITLE: Funtion of Dachsous cadherin during Droshopila imaginal development.
Instituto de Neurociencias, CSIC-UMH. Alicante (Spain) 2005.
TITLE: Funtion of Dachsous cadherin during Droshopila imaginal development.
Instituto de Neurociencias, CSIC-UMH. Alicante (Spain) 2005.
TITLE: Role of Dachsous cadherin during Drosophila imaginal disc development.
Instituto Cajal. CSIC. Madrid (Spain) 2006
TITLE: Different roles of atypical cadherins during Drosophila development. Red
Nacional de Adhesión y Migración Celular (RAMIC). Madrid (Spain) 2008
TITLE: Drosophila as a model for the study of Usher syndrome and Non-syndromic
Hearing Loss. Hearing and Deafness CIBERER Workshop. Valencia (Spain) 2009