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ORGAN/TISSUE
FAILURE RESEARCH
3-D ILLUSTRATED
BOOK PROJECT
A Collaborative Research Project Based on the
California State Standards in Biology Grades 9-12
Claire Carey
Santa Barbara High School
UCSB RET II 2006
Carey
Page 2
CP BIO
ORGAN/TISSUE FAILURE RESEARCH PROJECT
This unit project focuses on organ/tissue failure. Many people are affected by
organ/tissue failure; you may even have some family members or friends that have
experienced some form of organ/tissue failure. I suggest that you choose an illness that
has affected someone you know, you have heard about in the news, or interests you
because it is unusual. The goal is to research the illness and to orally/visually present
information and recent research through a group 3-D book/informational video. Be
creative, have fun, and use colorful artwork.
Organ/Tissue
Description
Websites
Failure
Blood Diseases
There is a range of
http://www.nhlbi.nih.gov
diseases of the blood,
from hemophilia, to
http://kidshealth.org
sickle cell, to
thrombocytopenia.
http://www.mayoclinic.com
http://www.findahematologist.org
http://www.merck.com
http://familydoctor.org
http://www.americasblood.org
http://www.nlm.nih.gov/medlineplus
Cardiac
Arrhythmias
An arrhythmia refers to
http://www.acc.org/media/patient/chd/cardiac%5Farr
any change from the
hythmias
normal sequence of
electrical impulses,
http://www.americanheart.org
causing abnormal heart
rhythms. This can
http://www.hrspatients.org
cause the heart to
pump less effectively.
http://www.mayoclinic.com
http://familydoctor.org
http://www.womensheartfoundation.org
Cirrhosis of the
Cirrhosis is a condition
Liver
that causes irreversible
scarring of the liver. As
scar tissue replaces
http://www.nlm.nih.gov/medlineplus
http://www.liverfoundation.org
Carey
Page 3
normal tissue, blood
CP BIO
http://www.merck.com
flow through your liver
is affected, making it
http://www.liverfoundation.org
increasingly difficult
for your liver to carry
http://www.classkids.org
out functions that are
essential for life and
http://digestive.niddk.nih.gov
health.
http://www.mayoclinic.com
http://www.gastro.org
Digestive
Functional disorders
Disorders
are those in which the
bowel looks normal but
http://www.iffgd.org/GIDisorders/GImain.html
http://www.clevelandclinic.org/health
doesn't work properly.
They are the most
http://www.acg.gi.org
common problems
affecting the colon and
http://www.gastro.org
rectum and include
constipation and
http://www.cvsaonline.org
irritable bowel
syndrome.
http://digestive.niddk.nih.gov
http://www.nlm.nih.gov/medlineplus
Eye Diseases
The leading causes of
http://www.nei.nih.gov/health/examples
vision impairment and
blindness in the United
http://familydoctor.org
States are primarily
age-related eye
http://www.preventblindness.org/eye_problems/signs
diseases. From
adults.html
cataract disease to
glaucoma and many
http://www.aao.org
more.
http://www.asoprs.org
http://www.restoresight.org
http://www.nlm.nih.gov/medlineplus
Heart Disease
Heart disease is a
http://familydoctor.org
general term that
refers to a variety of
http://www.merck.com
acute and chronic
medical conditions that
http://www.mayoclinic.com
Carey
Page 4
CP BIO
affect one or more of
the components of the
http://www.nhlbi.nih.gov
heart.
http://www.nlm.nih.gov/medlineplus
http://www.labtestsonline.org/understanding/conditio
ns/heart.html
http://www.womensheartfoundation.org/
http://www.cdc.gov/nccdphp
http://www.americanheart.org
http://www.acc.org
Kidney Disease
Kidney disease results
http://www.nkdep.nih.gov/patients/kidney_disease
from damage to the
nephrons, the tiny
http://kidney.niddk.nih.gov/kudiseases
structures inside your
kidneys that filter
http://www.nlm.nih.gov/medlineplus/kidneydiseases
blood.
http://www.labtestsonline.org/understanding/conditio
ns/kidney.html
http://www.aakp.org
http://www.auanet.org
http://www.kidney.org
Kidney Failure
The kidneys stop
http://www.nkdep.nih.gov/patients/kidney_disease
working when illness or
injury keeps them from
http://kidney.niddk.nih.gov/kudiseases
filtering properly. In
kidney failure, these
http://www.nlm.nih.gov/medlineplus/kidneydiseases
bacteria and salts build
up and can have bad
http://www.labtestsonline.org/understanding/conditio
effects on the heart,
ns/kidney.html
brain, lungs, and other
organs. This may even
http://www.aakp.org
cause serious illness or
death.
http://www.auanet.org
http://www.kidney.org
Carey
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CP BIO
http://www.aafp.org
http://www.lifeoptions.org
Liver Disease
Liver disease can
http://www.nlm.nih.gov/medlineplus
manifest itself in many
different ways.
http://www.liverfoundation.org
Manifestations of liver
disease that are
http://www.merck.com
particularly important
include jaundice,
http://www.liverfoundation.org
cholestasis, liver
enlargement, portal
http://www.classkids.org
hypertension, ascites,
liver encephalopathy,
http://digestive.niddk.nih.gov
and liver failure.
Lung Diseases
There are many types
http://jama.ama-
of lung diseases such
assn.org/cgi/reprint/283/14/1922.pdf
as asthma, chronic
bronchitis,
http://www.4woman.gov/faq/lung_disease
emphysema, cystic
fibrosis, respiratory
http://www.chestnet.org
failure, pulmonary
edema, pulmonary
http://www.lungusa.org
embolism, and
pulmonary
http://www.nhlbi.nih.gov
hypertension.
http://www.niaid.nih.gov
http://www.nlhep.org
Muscle
Disorders
When any problem
http://www.nlm.nih.gov/medlineplus
related to muscle
function occurs, the
http://patients.uptodate.com
result is weakness. But
weakness has many
http://www.aaos.org
causes, only some of
which are related to
http://www.mdausa.org
actual disease of the
muscles.
http://www.niams.nih.gov
http://www.ninds.nih.gov
Neurologic
Because your brain and
http://www.nlm.nih.gov/medlineplus
Carey
Disorders
Page 6
central nervous system
control so much of
http://www.thinkneurologynow.org
you, it is the most
complex part of your
http://www.neurosurgeon.org
body. Problems with
the brain—called
http://www.ninds.nih.gov
neurological
disorders—can affect
http://web.sfn.org
your movement,
speech, memory,
http://kidshealth.org
senses, swallowing,
breathing, learning,
http://www.mayoclinic.com
and more.
Pancreatic
Diseases
There are many
http://www.pancreasfoundation.org
pancreatic diseases.
The pancreas is a
http://www.gastro.org/
narrow, flat organ
located below the liver,
http://www.nlm.nih.gov/medlineplus
between the stomach
and the spine. It helps
http://www.niddk.nih.gov
regulate blood sugar
and digest fats,
http://www.shwachman-diamond.org
proteins, and
carbohydrates.
http://digestive.niddk.nih.gov
http://www.labtestsonline.org
Skin Conditions
There are many skin
http://familydoctor.org
diseases that range
from rashes to life-
http://www.nlm.nih.gov/medlineplus
threatening diseases.
http://www.aad.org
http://www.asds-net.org
http://www.scalyskin.org
http://www.niams.nih.gov
Spleen Diseases
Diseases of the spleen
http://www.merck.com
interfere with filtering
blood and the
http://familydoctor.org
production of white
blood cells called,
which in turn produce
http://www.nlm.nih.gov/medlineplus
CP BIO
Carey
Thyroid Disease
Page 7
antibodies.
http://www.nhlbi.nih.gov
The thyroid is a gland
http://www.nlm.nih.gov/medlineplus
that controls key
functions of your body.
http://www.medem.com
Disease of the thyroid
gland can affect nearly
http://www.hormone.org
every organ in your
body and harm your
http://www.thyroid.org
health. Goiter,
hyperthyroidism, and
http://www.mayoclinic.com
hypothyroidism are
Ulcers
just a few to start with.
http://jama.ama-assn.org
An ulcer is a break in
http://www.nlm.nih.gov/medlineplus
the lining of the
stomach or in the
http://familydoctor.org
duodenum (the first
part of the small
http://www.acg.gi.org
intestine).
http://www.gastro.org
http://www.cdc.gov/ncidod/dbmd
http://www.niddk.nih.gov
Uterine
Diseases
There are many uterine
http://familydoctor.org
diseases that range
from cervicitis to
http://www.nlm.nih.gov/medlineplus
polyps to cancer.
http://www.acog.org
http://www.4woman.gov
http://www.medem.com
CP BIO
Carey
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CP BIO
Group Names: ____________Organ/Tissue Failure: _____________ Peer Grader: ___________
ORGAN/TISSUE FAILURE GRADING RUBRIC
Presentation Requirements
Introduction

Name the organ/tissue failure

Introduce team members
Definition of the organ/tissue failure

Which organ is affected?

What happens to the organ?
Original function of the organ/tissue

Earned
Possible
Points
Points
20
20
20
What was the original job of the
organ/tissue?

What is the organ/tissue not able to
do with the illness?
Description of the symptoms

10
List all of the possible effects on
the body
Possible causes of the organ/tissue failure

20
Are there environmental or health
factors that can cause the illness?

Can the illness be inherited?
Prevention

10
What can be done to prevent
getting this organ/tissue failure?
How the organ/tissue failure is treated

Medications? Surgery?

Nutrition? Lifestyle choices?
How the organ/tissue failure is diagnosed

20
10
What tests are done?
How many and what type of people are
20
likely to have the disorder

Is it more common in a certain
group of people?

How common is it?
Application of research article

10
What new information did you learn
from your research?
Presentation

20
Do you have illustrations or
graphics for each page?

Is the information legible and neat?
Total Points Earned
180
Comments
Carey
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CP BIO
ORGAN/TISSUE FAILURE TOPIC SHEET
1. What type of organ/tissue failure do you want to research? ______________
2. Who is your partner? ____________________________
ORGAN/TISSUE FAILURE TOPIC SHEET
1. What type of organ/tissue failure do you want to research? ______________
2. Who is your partner? ____________________________
ORGAN/TISSUE FAILURE TOPIC SHEET
1. What type of organ/tissue failure do you want to research? ______________
2. Who is your partner? ____________________________
ORGAN/TISSUE FAILURE TOPIC SHEET
1. What type of organ/tissue failure do you want to research? ______________
2. Who is your partner? ____________________________
ORGAN/TISSUE FAILURE TOPIC SHEET
1. What type of organ/tissue failure do you want to research? ______________
2. Who is your partner? ____________________________
Carey
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CP BIO
ORGAN/TISSUE FAILURE RESEARCH PROJECT SIGN-UP
Partner Names
Organ/Tissue
Failure
Article
Presentation
Format
Carey
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CP BIO
ORGAN/TISSUE FAILURE 3-D BOOK RESEARCH SHEET
Research Site: _______________________________________________________
Presentation Requirements
Research
Definition of the organ/tissue failure

Which organ is affected?

What happens to the organ?
Original function of the organ/tissue

What was the original job of the organ/tissue?

What is the organ/tissue not able to do?
Description of the symptoms

List all of the possible effects on the body
Possible causes of the organ/tissue failure

Are there environmental or health factors?

Can the illness be inherited?
Prevention

What can be done to prevent getting this
organ/tissue failure?
How the organ/tissue failure is treated

Medications? Surgery?

Nutrition? Lifestyle choices?
How the organ/tissue failure is diagnosed

What tests are done?
How many and what type of people are likely to have the
disorder

Is it more common in a certain group of people?

How common is it?
ORGAN/TISSUE FAILURE 3-D BOOK RESEARCH SHEET
Research Site: _______________________________________________________
Presentation Requirements
Definition of the organ/tissue failure

Which organ is affected?

What happens to the organ?
Original function of the organ/tissue

What was the original job of the organ/tissue?

What is the organ/tissue not able to do?
Description of the symptoms

List all of the possible effects on the body
Possible causes of the organ/tissue failure

Are there environmental or health factors?

Can the illness be inherited?
Prevention

What can be done to prevent getting this
organ/tissue failure?
How the organ/tissue failure is treated

Medications? Surgery?

Nutrition? Lifestyle choices?
How the organ/tissue failure is diagnosed

What tests are done?
How many and what type of people are likely to have the
disorder

Is it more common in a certain group of people?

How common is it?
Research
Carey
Page 12
CP BIO
ORGAN/TISSUE FAILURE 3-D BOOK RESEARCH SHEET
Research Site: _______________________________________________________
Presentation Requirements
Research
Definition of the organ/tissue failure

Which organ is affected?

What happens to the organ?
Original function of the organ/tissue

What was the original job of the organ/tissue?

What is the organ/tissue not able to do?
Description of the symptoms

List all of the possible effects on the body
Possible causes of the organ/tissue failure

Are there environmental or health factors?

Can the illness be inherited?
Prevention

What can be done to prevent getting this
organ/tissue failure?
How the organ/tissue failure is treated

Medications? Surgery?

Nutrition? Lifestyle choices?
How the organ/tissue failure is diagnosed

What tests are done?
How many and what type of people are likely to have the
disorder

Is it more common in a certain group of people?

How common is it?
ORGAN/TISSUE FAILURE 3-D BOOK RESEARCH SHEET
Research Site: _______________________________________________________
Presentation Requirements
Definition of the organ/tissue failure

Which organ is affected?

What happens to the organ?
Original function of the organ/tissue

What was the original job of the organ/tissue?

What is the organ/tissue not able to do?
Description of the symptoms

List all of the possible effects on the body
Possible causes of the organ/tissue failure

Are there environmental or health factors?

Can the illness be inherited?
Prevention

What can be done to prevent getting this
organ/tissue failure?
How the organ/tissue failure is treated

Medications? Surgery?

Nutrition? Lifestyle choices?
How the organ/tissue failure is diagnosed

What tests are done?
How many and what type of people are likely to have the
disorder

Is it more common in a certain group of people?

How common is it?
Research
Carey
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CP BIO
“ REQUEST” Directed Reading-Thinking Activity
Organ/ Tissue Failure Article
Directions:
1. Silently read to the first stop.
2. Think of a question for this section using one of the question
words (who, what, when, where, why, how).
3. When everyone has finished reading, ask your questions this way:
a. One person begins by calling upon a
member of the group and then asking
the question.
Rules for question time:
1. “I don’t know is not an
b. That person must answer the
acceptable answer.
question as best as s/he can without
2. Each reader needs to
looking back at the article.
c. The asker determines whether or not
the answer is acceptable.
think of a question and
ask it of someone in
the group.
d. The person who answers gets to ask
3. When answering
the next question.
questions, there is no
e. Continue until everyone has had a
looking back at the
chance to ask/answer a question for
this section.
4. Continue reading each section and stopping
article (turn article
over).
to ask questions as described above.
5. Choose a score keeper to record how many points people in your
group earned. The person with the most points in each group will
earn extra points.
Name
Points Earned
Carey
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CP BIO
Directions: For each section you read, create a question and write it in
one of these shapes.
WHO?
WHAT?
WHEN?
WHERE?
HOW?
WHY?
Carey
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CP BIO
ORGAN/TISSUE FAILURE 3-D BOOK SELF EVALUATION
Presentation Requirements
Definition of the organ/tissue failure

Which organ is affected?

What happens to the organ?
Cumulative Research
Points
_____
20
Sites: ___________________________
Original function of the organ/tissue

What was the original job of the
_____
10
organ/tissue?

What is the organ/tissue not able to
do with the illness?
Sites: ___________________________
Description of the symptoms

List all of the possible effects on the
_____
20
body
Sites: ___________________________
Possible causes of the organ/tissue failure

Are there environmental or health
_____
10
factors that can cause the illness?

Can the illness be inherited?
Sites: ___________________________
Prevention

What can be done to prevent getting
_____
30
this organ/tissue failure?
Sites: ___________________________
How the organ/tissue failure is treated
_____

Medications? Surgery?
20

Nutrition? Lifestyle choices?
Sites: ___________________________
How the organ/tissue failure is diagnosed

What tests are done?
_____
20
Sites: ___________________________
How many and what type of people are likely
to have the disorder

_____
20
Is it more common in a certain group
of people?

How common is it?
Sites: ___________________________
Application of research article

What new information did you learn
_____
10
from your research?
Resource: ________________________
Presentation

Do you have illustrations or graphics
_____
20
for each page?

Is the information legible and neat?
Total Points Earned
_____
180
Carey
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CP BIO
Organ/Tissue Failure 3-D Book Job Worksheet
Partner
1
3-D BOOK PAGES
Title: Poster Title, team members (in smaller font)
Definition: Which organ is affected? What happens to the organ?
Original Function: What was the original job of the organ/tissue? What
is the organ/tissue not able to do with the illness?
2
Symptoms: What are the effects on the body?
Causes: Are there environmental or health factors that can cause the
illness? Can the illness be inherited?
3
Prevention: What can be done to prevent getting this organ/tissue
failure?
Treatment: Medications? Surgery? Nutrition? Lifestyle choices?
Diagnosis: What tests are done?
4
Frequency in Population: more common in certain group; how
common it is
Article: new information found from research
Presentation: Do you have illustrations or graphics for each page? Is
the information legible and neat?
Organ/Tissue Failure 3-D Book Job Worksheet
Partner
1
3-D BOOK PAGES
Title: Poster Title, team members (in smaller font)
Definition: Which organ is affected? What happens to the organ?
Original Function: What was the original job of the organ/tissue? What
is the organ/tissue not able to do with the illness?
2
Symptoms: What are the effects on the body?
Causes: Are there environmental or health factors that can cause the
illness? Can the illness be inherited?
3
Prevention: What can be done to prevent getting this organ/tissue
failure?
Treatment: Medications? Surgery? Nutrition? Lifestyle choices?
Diagnosis: What tests are done?
4
Frequency in Population: more common in certain group; how
common it is
Article: new information found from research
Presentation: Do you have illustrations or graphics for each page? Is
the information legible and neat?
Carey
Page 17
CP BIO
Organ/Tissue Failure 3-D Book Checklist
Team Members: ____________________________ Organ/Tissue Failure: ___________________
3-D BOOK PAGES

Book Cover: Project title (including the organ/tissue failure name), team members
Definition Page: Which organ is affected? What happens to the organ?
Original Function Page: What was the original job of the organ/tissue? What is the organ/tissue
not able to do with the illness?
Symptom Panel: What are the effects on the body?
Cause Page: Are there environmental or health factors that can cause the illness? Can the illness
be inherited?
Prevention Page: What can be done to prevent getting this organ/tissue failure?
Treatment Page: Medications? Surgery? Nutrition? Lifestyle choices?
Diagnosis Page: What tests are done?
Frequency in Population Page: Is it more common in a certain group of people? How common is
it?
Article Panel: What new information was found from your research article?
Presentation: Do you have illustrations or graphics for each page? Is the information legible and
neat?
Organ/Tissue Failure 3-D Book Checklist
Team Members: ____________________________ Organ/Tissue Failure: ___________________
3-D BOOK PAGES

Book Cover: Project title (including the organ/tissue failure name), team members
Definition Page: Which organ is affected? What happens to the organ?
Original Function Page: What was the original job of the organ/tissue? What is the organ/tissue
not able to do with the illness?
Symptom Panel: What are the effects on the body?
Cause Page: Are there environmental or health factors that can cause the illness? Can the illness
be inherited?
Prevention Page: What can be done to prevent getting this organ/tissue failure?
Treatment Page: Medications? Surgery? Nutrition? Lifestyle choices?
Diagnosis Page: What tests are done?
Frequency in Population Page: Is it more common in a certain group of people? How common is
it?
Article Panel: What new information was found from your research article?
Presentation: Do you have illustrations or graphics for each page? Is the information legible and
neat?
Carey
Page 18
CP BIO
Group Names: ____________________ Organ/Tissue Failure: _______________ Grader Name:_________
ORGAN/TISSUE FAILURE 3-D BOOK PEER REVIEW
Presentation Requirements
Introduction

Name the organ/tissue failure

Introduce team members
Definition of the organ/tissue failure

Which organ is affected?

What happens to the organ?
Original function of the organ/tissue

Earned
Possible
Points
Points
20
20
20
What was the original job of the
organ/tissue?

What is the organ/tissue not able to do
with the illness?
Description of the symptoms

10
List all of the possible effects on the
body
Possible causes of the organ/tissue failure

20
Are there environmental or health
factors that can cause the illness?

Can the illness be inherited?
Prevention

10
What can be done to prevent getting
this organ/tissue failure?
How the organ/tissue failure is treated

Medications? Surgery?

Nutrition? Lifestyle choices?
How the organ/tissue failure is diagnosed

20
10
What tests are done?
How many and what type of people are likely to
20
have the disorder

Is it more common in a certain group of
people?

How common is it?
Application of research article

10
What new information did you learn
from your research?
Presentation

20
Do you have illustrations or graphics
for each page?

Is the information legible and neat?
Total Points Earned
What did you like about their presentation?
What could this group improve on?
180
Comments