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MBBS II (Second) Professional Examination 2011-12 Course Code:MBS202 Paper ID: 0312105 Microbiology - I Time: 2 Hours 40 Minutes Max Marks: 30 Note: Attempt all questions. Draw proper diagrams to support your answer. Part ‘B’ 1. Enumerate bacterial agents causing meningitis. Discuss the laboratory diagnosis of meningitis under the following headings-collection and transport of specimen, microscopy, isolation and identification and antigen detection. (7) 2. Classify streptococci. Enumerate virulence factors and diseases caused by streptococcus pyogenes. Discuss the pathogenesis and laboratory diagnosis of sore throat. (7) 3. Write short notes on: Structure and function of bacterial capsule Categories and segregation of hospital waste Pasteurization Mechanism of type I hypersensitivity (2x4=8) a) b) c) d) (2x4=8) a) b) c) d) Write in brief about: Laboratory diagnosis of gas-gangrene Principle of agglutination and its examples VDRL test Culture of Mycobacterium tuberculosis 4. MBBS II (Second) Professional Examination 2011-12 Roll No. Student’s Name Student’s Signature Invigilator’s Signature Course Code:MBS202 Paper ID: 0312105 Microbiology - I Part ‘A’ Time: 20 Minutes Max Marks: 10 Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes. 2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed. 3. For answering please use Ball- pen only. Q.1 The India ink preparation in suitable for demonstration of: a) Capsulated organism b) Non capsulated organism c) Motile organism d) Non motile organism Q.6 One of the causative agent of non gonococcal urethritis is: a) Streptococcus pyogenes b) Escherichia cali c) Chlamydia trachomatis d) Neisseria gonorrhea Q.2 Which of the following is an example of zoonotic disease? a) Polio myelitis b) AIDS c) Diphtheria d) Plague Q.7 Q.3 CD 8 surface antigen is present in: a) Helper T cells of Th 1 type b) Cytotoxic T cells c) Helper T cells of Th 2 type d) Delayed type hypersensitivity tolls A 25 year old man is said to be infected with a multidrug resistant strain of M. tuberculosis (MDR strain). The strain is: a) Susceptible only to isoniazid b) Resistant to isoniazid and streptomycin c) Resistant to isoniazid and ciproflox d) Resistant to both isoniazid and rifampicin Q.8 Which of the culture medium stimulates rapid growth of corynebactrium diphtheria? a) Potassium telurite blood agar b) Lowenstein Jensen medium c) Chocolate blood agar d) Loffler’s serum slope Q.9 Gram staining of a urethral smear from a man shows Gram negative diplococci inside the polymorphonuclear cells. The organism is: a) Haemophilus influenza b) Neisseria gonorrhea c) Streptococcus pneumoniae d) Escherichia coli Q.4 Q.5 A single unipolar arrangement of flagellum is known as: a) Lophotrichous b) Ampitrichous c) Monotrichous d) Peritrichous ‘Rough, tough and buff’ colonies on Lowenstein Jensen (LJ) medium are characteristic of: a) Mycobacterium tuberculosis b) Mycobacterium bovis c) Mycobacterium fortuitum d) Mycobacterium Kansasii PTO 10. Acute Rheumatic fever is a non suppurative sequelae of: a) Group D speptococci b) Group B Speptococci c) Group C Speptococci d) Group A Speptococci 11. Soft chancres or chancroid is caused by: a) Haemophilus ducreyi b) Treponema pallidum c) Neisseria gonorrhoeae d) Chlamydia trachomatis 12. A form of genetic exchange through a bacterial virus is: a) Conjugation b) Transformation c) Transposition d) Transduction Q.13 The method of steam sterilization at 100°C for 30 minutes on three consecutive days is known as: a) Tyndallization b) Inspissation c) Filteration d) Pasteurization Q.14 One of the following is a cause of neonatal meningitis: a) Group C streptococci b) Group B streptococci c) Group A streptococci d) Group D streptococci Q.15 Which of the following bacterial species cause pseudomembrane colitis? a) Escherichia coli b) Shigella dysenteriae c) Vibria parahaemolyticus d) Clostridium difficile Q.16 Nagler’s reaction is used identification of: a) Clostridium perfringens b) Clostridium botulinum c) Clostridium tetani d) Clostridium septicum Q.17 Which of the following types of leprosy is the most infection? a) Lepromatous Leprosy (LL) in the b) c) d) Borderline Lepromatus (BL) Borderline Tuberculoid (BT) Hyper reactive Tuberculoid (TT) Q.18 Organisms growing referred to as: a) Mesophiles b) Halophiles c) Psychrophiles d) Thermophiles Q.19 Which of the following is not involved in gas-gangrene? a) Clostridium perfringens b) c) d) Q.20 below 10°C Clostridium tetahi Clostridium novyi Clostridium histolyticum The causative agent of ‘Hard Chancre’ is: a) Chlamydia Machomatis b) Treponema pallidum c) Leptospira d) Nesseria gonorrhoeae are