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Chemistry Overview chemistry The study of the structure of matter; the composition of substances, and how they react with each other Mutual attraction or sympathy; rapport: The chemistry was good between the partners. chem·i·cal Abbr. chem. Adjective 1.Of or relating to chemistry. 2. Of or relating to the properties or actions of chemicals. Noun-1. A substance with a distinct molecular composition that is produced by or used in a chemical process. 2. A drug, especially an illicit or addictive one. — chem¹i·cal·ly adverb element A substance that cannot be broken down into any simpler substance by normal means. There are 92 naturally occurring elements. For example: carbon, oxygen, hydrogen, gold, silver, iron, etc. atom The smallest part of an element that possesses all the properties of that element. molecule The unit that results when two or more atoms bond together. The atoms can be the same element or two or more different elements.