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PRINCIPLES OF BIOMEDICAL SCIENCE
Syllabus
Bob Jones High School
650 Hughes Road
Madison, AL 35758
Teacher:
Email:
Phone:
Melinda Lawson
[email protected]
256-772-2547 Room N210
Course Description:
Principles of Biomedical Science
This course provides an introduction to the biomedical sciences through exciting handson projects and problems. Students investigate concepts of biology and medicine as they
explore health conditions including heart disease, diabetes, sickle-cell disease,
hypercholesterolemia, and infectious diseases. They will determine the factors that led to
the death of a fictional woman as they sequentially piece together evidence found in her
medical history and her autopsy report. Students will investigate lifestyle choices and
medical treatments that might have prolonged the woman’s life and demonstrate how the
development of disease is related to changes in human body systems. The activities and
projects introduce students to human physiology, basic biology, medicine, and research
processes and allow students to design experiments to solve problems. Key biological
concepts including maintenance of homeostasis in the body, metabolism, inheritance of
traits, and defense against disease are embedded in the curriculum. This course is
designed to provide an overview of all the courses in the biomedical sciences program
and lay the scientific foundation for subsequent courses.
Course Objectives:
Course objectives are unit specific and numerous. Please see the attached list of the
entire list of objectives.
Classroom Expectations:
Students must comply with the following rules:
1. Bring all needed materials to class
2. Be in your seat and ready to work when the bell rings
3. Be respectful and polite to everyone.
4. Be respectful of others’ property. This includes property belonging to the school
5. Handle lab equipment only when instructed by the teacher.
6. Absolutely no eating food or drinking beverages (includes water) in class!
7. No chewing gum in class!
8. Obey all school rules (see student handbook)
Any distractions that interfere with the student learning process will face the following
consequences:
1. First offense: Verbal warning
2. Second offense: Detention and parental notification
3. Third offense: Office referral and parental notification
BJ Grading Policy:
Grading scale:
A 90-100
B 80-89
C 70-79
D 65-69
F
0-64
Tests, projects & papers=70%
Homework, Class work, Quizzes & Participation=30%
BJ Make-up Test Policy:
Make-up tests will only be given to a student who has an excused absence. The student
Page 1
PRINCIPLES OF BIOMEDICAL SCIENCE
Syllabus
Bob Jones High School
650 Hughes Road
Madison, AL 35758
Teacher:
Email:
Phone:
Melinda Lawson
[email protected]
256-772-2547 Room N210
must make arrangements with the teacher. Tests may be taken on Thursday at 7:00 am.
Text and Other Required
Reading:
No textbook is required. Our curriculum is completely online. We will be utilizing online
data searches as part of the curriculum.
Materials and Supplies
Needed:
White long sleeve lab coat with length to mid-thigh( more information to come)
Blue or black pens
Notebook paper
2 inch 3 ring binder
2 packs of notebook dividers with tabs
1 roll of paper towel
1 Box of Kleenex
Concerning laptop utilization:
1. Under no circumstances are student laptops to be wired to the network or have print capabilities.
2. No discs, flash drives, jump drives, or other USB devices will be allowed.
3. Neither the teacher, nor the school is responsible for broken, stolen, or lost laptops.
4. Laptops will be used at the individual discretion of the teacher.
Note:
1. The academic misconduct policy of the school will be followed in this course.
2. The attendance policy of the school will be followed for this course.
3. Any student who receives failing grades during this course is urged to discuss this with the teacher immediately.
Course overview: Principles of the Biomedical Sciences™ Course Overview
The Principles of the Biomedical Sciences (PBS) course is divided into six units designed to introduce students to the study
of human biology and medicine. The following is a description of each unit in the PBS course.
Unit 1 – The Mystery
Unit one provides the foundation and develops the theme for the course. Students are engaged by reading about a woman,
Anna Garcia, who is found dead in her home. Students investigate the scene, gather evidence, and then move to the lab to
analyze their findings. Through their examination of key evidence, students learn notebook organization, observation and
documentation skills, and well as the fundamentals of experimental design. Students are introduced to the structure of DNA
and investigate how basic molecular biology techniques can be used to connect suspects with a crime scene. In each unit of
the course, students obtain additional medical history information for Anna as well as details from her autopsy report as they
explore the various illnesses she encountered throughout her life. Students will maintain a medical file for Anna Garcia,
compile their ideas and findings over the duration of the course, and ultimately determine her cause of death in the final unit.
Unit 2 – Diabetes
Students walk through Anna Garcia’s diagnosis of diabetes by completing simulated laboratory tests. Given results of the
tests, students can deduce the basic biology of both Type 1 and Type 2 diabetes. Students investigate the connection
between insulin and glucose and discuss how feedback systems in the body regulate the function of key hormones.
Page 2
PRINCIPLES OF BIOMEDICAL SCIENCE
Syllabus
Bob Jones High School
650 Hughes Road
Madison, AL 35758
Teacher:
Email:
Phone:
Melinda Lawson
[email protected]
256-772-2547 Room N210
Students investigate the biochemical makeup of food and complete experiments to demonstrate the relationship between
energy and food. As students explore diabetes, they are introduced to basic chemistry, the structure and function of
macromolecules, and the relationship of these molecules to metabolic function. The causes, symptoms, treatments and side
effects of diabetes are studied as well as the life style implications associated with this disease. Students examine
complications related to diabetes and finally brainstorm and develop an innovation to help with the management or
treatment of the disease.
Unit 3 – Sickle Cell Disease
Students learn basic concepts of genetics and inheritance as they explore Anna Garcia’s struggle with sickle cell disease.
Students examine sickled red blood cells under a microscope and learn what life is like with the disease by reading and
writing patient diary entries. They simulate the process of protein synthesis, examine the assembly of the protein
hemoglobin, and demonstrate how sickle cell disease results from a mutation that alters a protein product. Students create
chromosome spreads, examine the structure of chromosomes, and show how traits are passed through generations on
these chromosomes in our cells. Students also discuss the bioethics of scientific research and explore the bounds of HIPAA
legislation.
Unit 4 – Heart Disease
Students examine the normal function of the human heart and investigate malfunctions in the cardiovascular system that
can lead to heart disease. Students complete a dissection to tour heart anatomy and study heart function using probes and
data acquisition software. They collect and analyze heart data including heart rate, blood pressure, and EKG readings and
analyze cardiac test results of Anna Garcia. Students explore the role cholesterol plays in the body. Students further their
knowledge of molecular biology as they run gel electrophoresis and complete RFLP analysis to diagnose familial
hypercholesterolemia. Students design models to simulate the function of a pump and design visuals to show interventions
for blocked coronary vessels.
Unit 5 – Infectious Disease
Students follow the spread of a simulated epidemic as engagement to a thorough examination of the agents of disease.
Students use clues from their investigation of Anna Garcia’s medical history to deduce that she was suffering from a
bacterial infection. Through a series of laboratory investigations, students learn the fundamentals of aseptic technique,
complete visual identification of bacterial morphology, use the Gram stain to examine bacterial cell structure, and run
metabolic tests to pinpoint the particular bacterium at the heart of the illness. Students explain the functioning of the human
immune system in a visual project and explore how this system is designed to protect against invaders.
Unit 6 – Post Mortem
In the final unit of the course, students put together all they have learned throughout the course to determine Anna Garcia’s
cause of death. Students will investigate the structure and function of key human body systems and relate the illnesses in
the course to a breakdown in these systems. Students will begin to recognize the coordination and interconnections of the
body systems required to maintain homeostasis, a precursor to the theme of the Human Body Systems course.
Page 3
PRINCIPLES OF BIOMEDICAL SCIENCE
Syllabus
Bob Jones High School
650 Hughes Road
Madison, AL 35758
Teacher:
Email:
Phone:
Melinda Lawson
[email protected]
256-772-2547 Room N210
18 – WEEK PLAN
Week
1
Introduction and Unit 1Unit One: The Mystery
Lesson 1.1: Investigating the Scene
Activity 1.1.1: A Mysterious Death
Activity 1.1.2: The Evidence
Project 1.1.3: Blood Spatter Analysis
Week
2
Lesson 1.2: DNA Analysis
Activity 1.2.1: What is DNA?
Activity 1.2.2: Structure of DNA
Activity 1.2.3: DNA Analysis
Week
3
Lesson 1.3: The Findings
Activity 1.3.1: The Autopsy
Activity 1.3.2: Was It a Crime?
Week
4
Unit Two: Diabetes
Lesson 2.1: What Is Diabetes?
Activity 2.1.1: Diagnosing Diabetes
Project 2.2.2: The Insulin Glucose Connection
Activity 2.1.3: Feedback
Lesson 2.2: The Science of Food
Project 2.2.1: Food Testing
Activity 2.2.2: Food Labels
Activity 2.2.3: The Biochemistry of Food
Activity 2.2.4: Energy in Food
Week
5
Week
6
Lesson 2.3: Life With Diabetes (16 days)
Activity 2.3.1: A Day in the Life of a Diabetic
Project 2.3.2: Diabetic Emergency!
Activity 2.3.3: Complications of Diabetes
Problem 2.3.4: The Future of Diabetes Management and Treatment
Week
7
Unit Three: Sickle Cell Disease
Lesson 3.1: The Disease
Activity 3.1.1: Blood Detectives
Activity 3.1.2: Sickle Cell Diaries
Week
8
Lesson 3.2: It’s In the Genes
Activity 3.2.1: Protein Synthesis
Activity 3.2.2: The Genetic Code
Activity 3.2.3: Does Changing One Nucleotide Make a Big Difference?
Page 4
PRINCIPLES OF BIOMEDICAL SCIENCE
Syllabus
Bob Jones High School
650 Hughes Road
Madison, AL 35758
Teacher:
Email:
Phone:
Week
9
Lesson 3.3: Chromosomes
Week
10
Lesson 3.4: Inheritance
Activity 3.4.1: Family Inheritance
Activity 3.4.2: What’s the Probability?
Activity 3.4.3: World Distribution of Sickle Cell Disease (Optional)
Week
11
Unit 4: Heart Disease
Lesson 4.1: Heart Structure
Activity 4.1.1: Path of Blood in the Heart
Activity 4.1.2: Anatomy of the Heart
Week
12
Lesson 4.2: The Heart at Work
Week
13
Unit 5 Lesson 4.3: Heart Dysfunction
Week
14
Lesson 4.4: Heart Intervention
Project 4.4.1: Unblocking the Vessels
Project 4.4.2: Heart Disease Intervention
Week
15
Melinda Lawson
[email protected]
256-772-2547 Room N210
Activity 3.3.1: How is DNA Passed Through the Generations
Activity 3.3.2: Chromosomes – A Closer Look
Activity 3.3.3: The Immortal Cells
Activity 3.3.4: Confidentiality
Project 4.2.1: Heart Rate
Project 4.2.2: Blood Pressure
Activity 4.2.3: EKG
Project 4.3.1: What is Cholesterol?
Activity 4.3.2: Hypercholesterolemia
Problem 4.3.3: The Heart as a Pump
Unit 6 Unit 5: Infectious Disease
Lesson 5.1: Infection
Activity 5.1.1: Contagious
Activity 5.1.2: Infectious Disease Agents
Activity 5.1.3: Isolating Bacteria
Activity 5.1.4: Gram Staining
Activity 5.1.5: Bacterial Identification
Project 5.1.6: Lines of Defense
Week
16
Unit 6: Post Mortem
Lesson 6.1: Analyzing Anna
Project 6.1.1: How Do the Parts Make a Whole?
Activity 6.1.2: How Did She Die?
Page 5
PRINCIPLES OF BIOMEDICAL SCIENCE
Syllabus
Bob Jones High School
650 Hughes Road
Madison, AL 35758
Week
17
Week
18
Teacher:
Email:
Phone:
Melinda Lawson
[email protected]
256-772-2547 Room N210
Catch up and complete all lessons
Review and standardized final exam.
This is a tentative schedule. We may move faster or slower than planned and will vary schedule to accommodate
class.
.
Page 6