Download SI Biol 256 Worksheet Unit 3 B 1.) Anemia occurs when there is

SI Biol 256 Worksheet Unit 3 B
1.) Anemia occurs when there is abnormally low oxygen-carrying capacity in the
blood, low Red Blood Cell count and low Hematocrit.
2.) Polycythemia vera results when mitosis occurs at an uncontrolled rate,
producing a high Hematocrit, high blood pressure and a reddening of the skin.
3.) All leukocytes originate from hemocytoblast (hemo – blood; cyto – cell; blaststem cell) which differentiate into myeloid stem cells and lymphoid stem cells.
4.) Myeloid stem cells become myeloblast or monoblast but also produce Red Blood
Cells; while lymphoid stem cells become lymphoblast
5.) Myeloblasts develop into eosinophils, neutrophils or basophils while monoblasts
develop into monocytes
6.) The neutrophils (70%) make up the highest percentage of White Blood Cells.
7.) Monocytes leave the circulation, enter tissues, and differentiate into
macrophages. (macrophages are highly mobile and actively phagocytic)
8.) Platelets are not cells but fragments of megakaryocytes which are kept inactive
by intact endothelial cells (nitric oxide and prostaglanding I2. These two
substances are synthesized by the intact, undamaged endothelial cells.)
9.) In hemostatis (series of reactions to stop bleeding), three phases occur in rapid
sequence:
1. vascular spasm/vasoconstriction in response to injury.
2. Platelet plug formation.
3. Coagulation in which blood clotting takes place.
10.) Coagulation is a reaction series called a coagulation cascade, in which one
inactive clotting factor becomes active and it in turn activates another clottig
factor
11.) Coagulation follows both extrinsic and intrinsic pathways, either are triggered
by tissue-damaging events.
HEMOCYTOBLAST
MYELOID
STEM CELLS
LYMPHOID
STEM CELLS
MYELOBLAST
MONOBLAST
LYMPHOBLAST
Eosinophils
Monocytes
Lymphocyte
Neutrophils
Basophils