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Integumentary System Diseases Integumentary System Diseases Congenital Skin Conditions Eczema A common skin condition characterized by reddening (erythema) and vesicle formation, which may lead to weeping and crusting. It is endogenous, or “constitutional”. This means that outside agents do not play a primary role. (Contrast this with ‘dermititis’, in which case outside agents DO play a primary role.) However in some contexts the terms ‘dermititis’ and ‘eczema’ are used interchangeably to refer to the symptoms of these skin conditions. There are five main types of eczema: Psoriasis 1. Atopic Eczema, which is associated with asthma and hay-fever. 2. Seborrhoeic Eczema (or Dermititis), typically affecting the scalp, eyelids, nose, and lips; associated with the presence of Pityrosporum yeasts; common among AIDS patients. 3. Discoid (or Nummular) Eczema, characterized by coin-shaped lesions and only occuring in adults. 4. Pompholyx, affecting only the hands and feet. 5. Gravitational (or Stasis) Eczema, associated with poor venous circulation (sometimes referred to as’Varicose Eczema’). A chronic skin disease in which scaly pink patches form on the elbows, knees, scalp, and other parts of the body. Psorisis is one of the commonest skin diseases in Britain, affecting about 2% of the population (cause unknown). This disorder often runs in families, the commonest time of onset being in adolesence. It sometimes occurs in association with arthritis. Occasionally the disease may be very severe, affecting much of the skin and causing considerable disability in the patient. While psychological stress may make psorisis worse, the only significant event thought to precipitate this condition is a preceeding streptococcal infection. Dermatitis An inflammatory condition of the skin caused by outside agents. (Contrast this with eczema, an endogenous disease in which outside agents do NOT play a primary role). Primary irritant dermatitis may occur in anyone who has sufficient contact with irritants such as acids, alkalis, solvents and (especially) detergents. Primary irritant dermatitis is the commonest cause of occupational dermatitis in hairdressers, nurses, cooks etc.. In the case of allergic contact dermatitis skin changes resembling those of eczema develop as a delayed reaction to contact with a particular allergen, which may be present at low concentrations. The commonest example of allergic contact dermatitis in women is nickel dermatitis due to the metal nickel used in jewellery, jeans studs etc, whereas In men chromium dermatitis is relatively common. Treatment of dermatitis depends on removing the cause, which is not always possible. Dermititis herpetiformis is an uncommon very itchy rash with symmetrical blistering, especially on the knees, elbows, buttocks and shoulders. It is related to sensitivity to gluten. Bacterial Skin Conditions Acne vulgaris A common inflammatory condition of the sebaceous glands. These grease-producing glands are under androgen control, but the cause of acne is unknown. It involves the face, back and chest and is characterized by the presence of blackheads with papules, pustules – and in more severe cases – cysts and scars. Acne is readily treatable. Impetigo A superficial bacterial infection of the skin. Nonbullous impetigo is caused by Staphylococcus aureus, Streptococcus species, or both organisms. It mainly affects young children and is highly contagious, with yellowishbrown crusting. Bullous impetigo is caused by Staphylococcus aureus. It is characterized by blisters, is less contagious than the nonbullous form, and occurs at any age. Acne Rosacea A chronic inflammatory disease of the face in which the skin becomes abnormally flushed. At times it may become pustular and there may be associated keratitis (inflammation of the cornea of the eye). The disease occurs in both sexes and at all ages but is most common in women in their thirties. The cause is unknown. Viral Skin Conditions Warts A wart is a benign growth on the skin caused by an infection with ‘human papillomavirus‘. (However, a few of the many types of this virus are known to be a causal factors in the production of tumours, which is why it is good advice to have new/unknown growths on the skin checked by a qualified person.) Common Warts firm horny papules (1-10mm in diameter) usually located on the backs of the hands. Most will clear spontaneously within two years. Plantar warts (or verrucae) can occur on the soles of the feet and are often tender and especially sensitive to pressure. Plane warts are flat, skin coloured, and therefore difficult to see. They are usually located on the face and may be present in very large numbers. Genital warts are frequently associated with other genital infections. Infected women have an increased risk of developing cervical cancer. Verrucas Also known as ‘Plantar Warts‘. Herpes Inflammation of the skin or mucous membranes that is caused by herpes viruses and characterized by collections of small blisters. There are two types of herpes. Herpes simplex There are two types of Herpes simplex (HSV): Type I causes the common cold sore , which is usually present on or around the lips. Type II is mainly associated with genital herpes and is sexually transmitted. Types I and I can both cause either genital herpes or cold sores, depending on the site of initial infection. HSV blisters are contagious through skin-to-skin contact and are recurrent in some people. HSV can also affect the conjunctiva. Herpes zoster Also known as “Shingles“, this is caused by the varicella-zoster virus, which also causes chickenpox. Following an attack of chickenpox, the virus lays dormant in the dorsal root ganglia of the spinal cord. Later, due to one of various stimuli, the virus may migrate down the sensory nerve to affect one or more dermatones on the skin in a band, causing the characteristic singles rash. One side of the face or eye (ophthalmic zoster) may be involved. Shingles may be chronically painfully (post-herpetic neuralgia), especially in the elderly. Fungal Skin Conditions Tinea corporis, manus, pedis Also known as “Ringworm“, this is a fungal infection that can affect the skin, the scalp, or the nails. Ringworm is caused by the dermatophyte fungi – species of Microsporum, Trichophyton, andEpidermophyton – and also affects non-human animals, which may be a source of infection for peope. It can be spread by direct contact or via infected materials. The lesions of ringworm may be ringlike and may cause intense itching. Tinea pedis (Athelete’s Foot) is the commonest form of ringworm and affects the skin between the toes. Tinea capitis is another common form of ringworm and affects the scalp. Tinea cruris is the form of ringworm that affects the groin and thighs. Tinea barbae is the form of ringworm that affects the skin under a beard. Ringworm is often treated with anti-fungal agents, which may either be taken by mouth (orally), or applied locally. Verrucas Plantar Warts – see above. Folliculitis Inflammation of the hair follicles in the skin, commonly caused by infection. Folliculitis may be caused by Pityrosporum yeasts. Boils Tender inflamed areas of skin that contain pus. The infection is usually caused by the bacterium Staphylococcus aureus entering through a hair follicle or a break in the skin. Local injury or lowered constitutional resistance may encourage the development of boils. These usually heal when the pus is released, or with antibiotic treatment (though occasionally the latter may cause more widespread infection). The medical name for a “boil” is a “furuncle”. Source: IvyRose Holistic. http://www.ivy-rose.co.uk/HumanBody/Skin/Skin_Disorders.php Eczema is a term for several different types of skin swelling. Eczema is also called dermatitis. It is not dangerous, but most types cause red, swollen and itchy skin. Factors that can cause eczema include other diseases, irritating substances, allergies and your genetic makeup. Eczema is not contagious. The most common type of eczema is atopic dermatitis. It is an allergic condition that makes your skin dry and itchy. It is most common in babies and children. Eczema is a chronic disease. You can prevent some types of eczema by avoiding irritants, stress, and the things you are allergic to. Impetigo is a skin infection caused by bacteria. It is usually caused by staphylococcal (staph) bacteria, but it can also be caused by streptococcal (strep) bacteria. It is most common in children between the ages of two and six. It usually starts when bacteria get into a break in the skin, such as a cut, scratch, or insect bite. Symptoms start with red or pimple-like sores surrounded by red skin. These sores can be anywhere, but usually they occur on your face, arms and legs. The sores fill with pus, then break open after a few days and form a thick crust. They are often itchy, but scratching them can spread the sores. Impetigo can spread by contact with sores or nasal discharge from an infected person. You can treat impetigo with antibiotics. Psoriasis is a skin disease that causes itchy or sore patches of thick, red skin with silvery scales. You usually get the patches on your elbows, knees, scalp, back, face, palms and feet, but they can show up on other parts of your body. Some people who have psoriasis also get a form of arthritis called psoriatic arthritis. A problem with your immune system causes psoriasis. In a process called cell turnover, skin cells that grow deep in your skin rise to the surface. Normally, this takes a month. In psoriasis, it happens in just days because your cells rise too fast. Psoriasis can be hard to diagnose because it can look like other skin diseases. Your doctor might need to look at a small skin sample under a microscope. Psoriasis can last a long time, even a lifetime. Symptoms come and go. Things that make them worse include infections, stress, dry skin, and certain medicines. Psoriasis usually occurs in adults. It sometimes runs in families. Treatments include creams, medicines, and light therapy. Rash – A rash is an area of irritated or swollen skin. Many rashes are itchy, red, painful, and irritated. Some rashes can also lead to blisters or patches of raw skin. Rashes are a symptom of many different medical problems. Other causes include irritating substances and allergies. Certain genes can make people more likely to get rashes. Contact dermatitis is a common type of rash. It causes redness, itching, and sometimes small bumps. You get the rash where you have touched an irritant, such as a chemical, or something you are allergic to, like poison ivy. Some rashes develop right away. Others form over several days. Although most rashes clear up fairly quickly, others are long-lasting and need long-term treatment. Because rashes can be caused by many different things, it’s important to figure out what kind you have before you treat it. If it is a bad rash, if it does not go away, or if you have other symptoms, you should see your health care provider. Treatments may include moisturizers, lotions, baths, cortisone creams that relieve swelling, and antihistamines, which relieve itching. Scleroderma means hard skin. It is a group of diseases that cause abnormal growth of connective tissue. Connective tissue is the material inside your body that gives your tissues their shape and helps keep them strong. In scleroderma, the tissue gets hard or thick. It can cause swelling or pain in your muscles and joints. Symptoms of scleroderma include calcium deposits in connective tissues, Raynaud’s phenomenon, a narrowing of blood vessels in the hands or feet, swelling of the esophagus, the tube between your throat and stomach, thick, tight skin on your fingers, and red spots on your hands and face. No one knows what causes scleroderma. It is more common in women. It can be mild or severe. Doctors diagnose scleroderma using your medical history, a physical exam, lab tests, and a skin biopsy. There is no cure, but various treatments can control symptoms and complications. Skin Aging – Your skin changes as you age. You might notice wrinkles, age spots and dryness. Your skin also becomes thinner and loses fat, making it less plump and smooth. It might take longer to heal, too. Sunlight is a major cause of skin aging. You can protect yourself by staying out of the sun when it is strongest, using sunscreen with an SPF of 15 or higher, wearing protective clothing, and avoiding sunlamps and tanning beds. Cigarette smoking also contributes to wrinkles. The wrinkling increases with the amount of cigarettes and number of years a person has smoked. Many products claim to revitalize aging skin or reduce wrinkles, but the Food and Drug Administration has approved only a few for sun-damaged or aging skin. Various treatments soothe dry skin and reduce the appearance of age spots. Skin Cancer – Skin cancer is the most common form of cancer in the United States. The two most common types are basal cell cancer and squamous cell cancer. They usually form on the head, face, neck, hands, and arms. Another type of skin cancer, melanoma, is more dangerous but less common. Anyone can get skin cancer, but it is more common in people who spend a lot of time in the sun or have been sunburned, have light-colored skin, hair and eyes, have a family member with skin cancer, and/or are over age 50. You should have your doctor check any suspicious skin markings and any changes in the way your skin looks. Treatment is more likely to work well when cancer is found early. If not treated, some types of skin cancer cells can spread to other tissues and organs. Treatments include surgery, radiation therapy, chemotherapy, photodynamic therapy (PDT), and biologic therapy. PDT uses a drug and a type of laser light to kill cancer cells. Biologic therapy boosts your body’s own ability to fight cancer. Skin Infections – Some common types of skin infections are bacterial such as cellulitis, impetigo, and staphylococcal infections as mentioned earlier. Other viral infections include shingles, warts, and herpes simplex. Fungal infections include athlete’s foot and yeast infections. Parasitic infections include body lice, head lice and scabies. Treatment of skin infections depends on the cause. Pigmentation Disorders – Pigmentation means coloring. Skin pigmentation disorders affect the color of your skin. Your skin gets its color from a pigment called melanin. Special cells in the skin make melanin. When these cells become damaged or unhealthy, it affects melanin production. Some pigmentation disorders affect just patches of skin. Others affect your entire body. If your body makes too much melanin, your skin gets darker. Pregnancy, Addison’s disease, and sun exposure all can make your skin darker. If your body makes too little melanin, your skin gets lighter. Vitiligo is a condition that causes patches of light skin. Albinism is a genetic condition affecting a person’s skin. A person with albinism may have no color, lighter than normal skin color, or patchy missing skin color. Infections, blisters and burns can also cause lighter skin.