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4TH ICI-RS: 5-7 JUNE 2013 SCIENTIFIC PROGRAMME THE W ATERSHED MEDIA CENTRE, BRISTOL, UK CHALLENGES FOR EACH TOPIC TEAM IN ICI-RS 2013 1. HOW HAS, AND WILL THIS SUBJECT HELP PATIENTS ? 2. WHAT ARE THE PRECISE RESEARCH QUESTIONS ? 3. WHAT EXPERIMENTS /TRIALS ARE NEEDED TO ANSWER EACH QUESTION? WEDNESDAY 5TH JUNE TIME ACTIVITY TITLES OF THINK-TANKS, DEBATES AND PROPOSITIONS Topic contact and interested members 12:30 Lunch and Registration in Watershed 3 13:30 Start of Meeting Think Tank 1 Think Tank 2 Think Tank 3 15:15 Do we know enough about the control of neurotransmitter release from the urothelium in normal physiology and pathology? “Which is the correct urodynamic test for the individual patient?” Aging and detrusor underactivity: is there a link? Damaser, Yamanashi Rosier, Giarenis, Valentini Wagg Daneshgari Tea Plenary Session (Cinema 3) 17:15 Do we need better methods of assessing urethral function? How important is myogenic activity in OAB/detrusor overactivity? END OF DAY ONE 19:30 Welcome dinner at the Riverstation Restaurant 15:45 Debate 1 16:30 Proposal 1 Sievert Chacko, Cortes The Think Tanks will be held in Waterside 1 and 2 and Cinema 3. All other activities will be plenary, and held in Cinema 3 THURSDAY 6TH JUNE TIME ACTIVITY 08:30 Think Tank 4 TITLES OF THINK TANKS, DEBATES AND PROPOSITIONS Topic contact Weiss, Bosch Desmopressin therapy patient selection: what nocturia and QoL improvement is needed to balance any risks? Gajewski, Zabbarova Think Tank 5 Does our limited knowledge of the mechanisms of neuromodulation limit its benefits for patients? Think Tank 6 Detrusor underactivity: what do we need to know; definition , associated disorders, treatment targets and methods? van Koeveringe, Ruggieri 10:15 Coffee 10:45 Proposal 2 Plenary Session (Cinema 3) Do we understand any more about LUT interstitial cells? 11:30 Reports Receive reports from Think Tanks 1, 2 & 3 12:30 Lunch 13:30 Proposal 3 14:15 Proposal 4 15:00 Tea 15:15 Proposal 5 16:00 Proposal 6 16:45 Reports Kanai, Ikeda, HannaMitchell What role does the bladder and urethral epithelium play in bladder sensation and sensory disorders, including pelvic pain? What is the role of covert infection in detrusor overactivity and other LUTD? Birder, How to (re) define useful biomarker systems for detrusor and sphincter under or overactivity? How are we going to make progress in treating bladder pain syndrome? Receive reports from Think Tanks 4, 5 & 6 Fry 17:30 END OF DAY TWO 19:30 Dinner at the Bordeaux Quay Restaurant Moore, Malykhina, Hanno The Think Tanks will be held in Waterside 1 and 2 and Cinema 3. All other activities will be plenary, and held in Cinema 3 FRIDAY 7TH JUNE TIME ACTIVITY TITLES OF THINK TANKS, DEBATES AND PROPOSITIONS Topic contact 09.00 Think Tank 7 What is the place of sacral nerve neuromodulation and/or intradetrusor BTXA injections in the treatment algorithm for OAB symptoms? What should be the inclusion criteria for OAB, BPO and NP trials? What is the best surgical intervention for stress urinary incontinence in the very young and very old? Hashim Plenary Session (Cinema 3) What is the relationship between pathophysiology and the success of OAB therapy ? Tannenbaum Smith (T) Think Tank 8 Think Tank 9 10:45 Coffee 11.15 Proposal 7 12.00 Debate 2 12:45 Lunch Have we optimised the dose, sites and frequency of BTXA injections? Robinson, Castro Radzizewski, Sahai Plenary Session (Cinema 3) 13:30 Reports Receive reports from Think Tanks 7, 8 & 9 14:15 Debate 3 OAB: a plea for a new definition, but is there any need? To discuss the 5th ICI-RS 2014 15:00 15:15 Drake Tea 19.00 Coach from Ibis Hotel to Berwick Lodge. 19.30 Dinner at Berwick Lodge for those from out of town, but marooned in Bristol overnight The Think Tanks will be held in Waterside 1 and 2 and Cinema 3. All other activities will be plenary, and held in Cinema 3