Download Classroom instruction, 2002

-1CURRICULUM VITAE
January 2003
George Wills Comstock
Part II
TEACHING
Advisees (in chronological order):
NAGUIB, Samir M.
Acceptance and Results of a Cervical Cytology Screening
Program in Washington County, Maryland.
Dr. P.H.
1966
GANLEY, James Powell
Epidemiology Characteristics of Presumed Ocular
Histoplasmosis.
Dr.P.H.
1971
THOMAS, David B.
Oral Contraceptives and Cervical Neoplasia.
Dr. P.H.
1971
NOMURA, Abraham M. Y.
The Relationship of Estrogenic Preparations to Benign Breast
Tumors.
Dr. P.H.
1974
SHAW, Robert
The Relationship of Respiratory Variables to Illness Absence
Resulting from Coronary Heart Disease.
Dr. P.H.
1975
ABUDEJAJA, Awad Hussein
Some Determinants of Compliance with Treatment Following
Community Blood Pressure Screening.
Ph.D.
1978
SUTRISNA, Bambang
Epidemiologic Characteristics of Pulmonary Tuberculosis and
a Suggested Control Program for Indonesia.
M.H.S.
1979
CAUTHEN, George McKinstry
Relationship Between Blood Pressure and Characteristics of
Drinking Water in A County Population.
Sc.D.
1980
-2McCARTER, Robert J. Jr.
Congenital Malformations in the Offspring of Diabetic
Women.
Sc.D.
1983
FREEMAN, Richard W.
Volume I. A Survey of Neurologic Symptoms among Members of
the International Brotherhood of Painters and Allied
Trades.
Volume II. A Survey of Neurologic Symptoms among Members
of the International Brotherhood of Painters and Allied
Trades.
Sc.D.
1985
MENKES, Marilyn Judith Spivak
Vitamins A, E, Selenium and Risk of Lung Cancer.
Ph.D.
1985
SCHOBER, Susan Elizabeth
Vitamin A, Vitamin E, Selenium, and Colon Cancer Risk.
Ph.D.
1985
TEPPER, Allison
A Follow-Up Study of Chronic Respiratory Disease in
Baltimore City Firefighters.
Ph.D.
1986
HSING, Ann Wu Fung-Fung
Pre-diagnostic Serum Hormones and Prostate Cancer.
Ph.D.
1987
LINKINS, Robert Wilson
Depressed Mood and Development of Cancer.
Ph.D.
1987
MAURER, Kurt R.
The Epidemiology of Gallstone Disease in the Mexican
American, Cuban American, and Puerto Rican Populations of
the United States, 1982-84.
Ph.D.
1987
MENON, Sreekumar
Rotavirus Diarrhea in Apache Children.
Study.
Ph.D.
A Case-Control
FISCHER, Ellen Pauline
Suicide by Jumping in the City of New York.
Ph.D.
1987
1988
-3KOPPIKAR, Aparna Mahesh
Can Hypertension Be a Predictor of Clinical Diabetes
Mellitus?
Ph.D.
1988
MEBANE, Irma Laurice
Depressive Symptomatology and Subsequent Morbidity: A
Followup Study of Washington County, Maryland Residents.
Ph.D.
1988
COBERLY, Jacqueline S.
A Comparison of the Immunogenicity of the Standard and Two
Low-Dose Hepatitis B Vaccine Regimens in Infants.
Ph.D.
1989
BASER, Michael E.
Distribution of Ventilation in the Aging Lung.
Ph.D.
1991
HAWKINS, Barbara Snyder
A Study of the Risk of Visual Impairment Attributable to
Ocular Histoplasmosis
Ph.D.
1992
SCOTT, Jean C.
A Study of Cigarette Smoking and the Risk Factors for Hip
Fracture in Elderly Women.
Dr.P.H.
1992
ALBERG, Anthony John
Structured Social Involvement and Cigarette Smoking among
Adolescents.
Ph.D.
1994
STREET, Debra Ann
A Population-based Case-control Study of the Association of
Myocardial Infarction and Serum Levels of Carotenoids and
alpha-tocopherals.
Ph.D.
1994
GEITER, Lawrence J.
Results of a Randomized, Controlled Trial to Assess the
Toxicity and Patient Adherence with Two Short-course
Regimens for the Prevention of Tuberculosis, a Two-month
Regimen of Rifampin and Pyrazinamide or a Four-month
Regimen of Rifampin Only, in Comparison with a Control
Regimen of Six-months of Isoniazid.
Ph.D.
1997
-4KIMURA, Moriya
Comparison between a Whole Blood Interferon-γ Release Assay
and Tuberculin Skin Testing for the Detection of Tuberculosis Infection among Patients at Risk for Tuberculosis
Exposure.
Post-Doctoral Fellow
1999
PAPADOPOULOS, Emily C.
A Prospective Study of Antiphospholipid Antibodies and
Incident Thrombotic Events in Systemic Lupus Erythematosus.
Sc.M.
1999
JORGENSON, Lindsey
MHS
ORAL EXAMINATIONS
Departmental
1997 Smith, Jennifer
1997 Henderson, Leigh (Alt)
1998 Henderson, Leigh
1998 Scher, Ann
1999 Lucas, Katherine
1999 Cowgill, Karen
2001 Marsh, Marta J.
2002 Merkin, Sharon
Preliminary
1997 Gruskin, Leslie
1997 Kacena, Katherine
1997 Weeks, Kathleen (Alt)
1997 Davidson, Michael
1998 Paredes, Patricia
1998 Sato, Reiko
1998 Ruhl, Constance
1999 Riley, Elise
2001 Sadaphal, Pankaj
2001 Fong, Christy
2001 Pope, Diana
2002 Hansen, Christy
2002 Shukla, Rajendra
2002 Khan, Aamir
2001
-5Final
1995
1996
1997
1997
1997
1998
1998
1999
2000
2000
2000
2001
2001
Faerstein, Eduardo (Alt)
Tangrea, Joseph A
Yeh, Hsin-Chieh
Wu, Kana (Alt)
Erickson, Ralph
Smit, Ellen
Rice, Amy
Rosenberg, Marsha
Sato, Reiko
Georgakopoulos, Dimitri
Ruhl, Constance
Bellette, Bahrie
Maher, Dana (Alt.)
Thesis Committees, 2002
Fong, Christy
Golub, Jonathan
Onawola, Ronald
Pope, Diana
Werther, Winifred
Classroom instruction, 2002
Epidemiologic Basis for Tuberculosis Control (340:612)
AM Session: 53 students
PM Session: 22 students
Summer Course: 9 students
Methods in Epidemiology, Summer Course, 23 students
Intermediate Epidemiology, Instructor
Design and Application of Case-Control Studies,
Instructor
RESEARCH GRANT PARTICIPATION (current listings)
Gene-Environment Interactions: The Odyssey Cohort
National Cancer Institute: 09/30/99 - 06/30/04
P.I.: Dr. K. J. Helzlsouer
Main objective: Population-based cohort study to examine the
broad impact of genetic variation in candidate genes and
their interaction with environmental exposures on cancer
incidence and survival, specifically health and aging.
Responsibilities: In addition to being a co-author (and editor)
on reports from this study, Dr. Comstock is primarily
responsible for community contacts, including a local
community research review committee, publicity, and
relationships with physicians and community agencies. He
participates in planning, conducting, and reporting of
individual studies under this grant.
-6Clue Studies: Evaluating Biomarkers of Carcinogenesis
National Cancer Institute:
04/01/00 - 03/31/05
P.I.:
Dr. K. J. Helzlsouer
Main objective:
To compare serum fatty acid synthase
concentrations in serum (plasma) samples taken at varying
time intervals prior to diagnosis in women with and without
breast cancer.
Responsibilities:
As above.
Career Research Award: Follow-up Studies of Cardio-Respiratory
Disease:
National Heart, Lung and Blood Institute:
04/01/64 - 3/31/04
P.I.: (Awardee): Dr. G. W. Comstock
Main objective: To provide partial financial support for a
career in research.
Responsibilities: This award provides partial support for Dr.
Comstock’s research in tuberculosis and his participation
in research based on linking the information from the
Washington County Serum Bank with outcomes determined in
The Atherosclerosis Risk in Communities (ARIC) study and
the Cardiovascular Health Study (CHS) among Washington
County participants.
ACADEMIC SERVICE (partial)
Division or Department
1994
Committee on Biology and Epidemiology
1994-95
Committee on Core Competencies
1996
General Knowledge Committee
School
c.1967-75
c.1980-present
c.1981
1991-95
c.1992
1993-94
Advisory Committee for General
Preventive Medicine Residency
Serology Committee for Training Center
for Public Health Research
Chair, Search Committee for Chair of
Department of Biostatistics
Committee on Professional Misconduct
Search Committee for Chair of Department
of Environmental Health Sciences
Data and Safety Monitoring Committee for
JHU/CDS Tuberculosis Chemoprophylaxis
Trial
-7PRESENTATIONS
Scientific Meetings:
Menkes M, Comstock G: Vitamins A and E and lung cancer
(abstract). Am J Epidemiol 120:491, 1984.
Klag MJ, Moore RD and Comstock GW: Alcohol and blood
pressure in American and Japanese executives (abstract).
Clin Res 34:371A, 1986.
Harlow S, Goldberg E and Comstock GW: Depressed mood and
widowhood: A prospective study of bereavement in elderly
women (abstract). Am J Epidemiol 124:505, 1986.
Menkes M and Comstock GW: Serum and dietary carotene
levels and lung cancer (abstract). Am J Epidemiol 124:502,
1986.
Sandler DP, Helsing KJ, Shore DL and Comstock GW: Heart
disease mortality in smokers and nonsmokers who live with
smokers. Am J Epidemiol 126:741, 1987.
Hsing AW, Polk BF, Comstock GW and Abbey H: Serum
androgens, vitamins, and subsequent prostate cancer
(abstract). Am J Epidemiol 126:766-767, 1987.
Helzlsouer, KJ, Comstock GW and Morris S: Selenium, betacarotene, and vitamins A and E -- a possible role in the
prevention of bladder cancer. Am J Epidemiol 128:930-931,
1988.
Hsing AW and Comstock GW: Serum hormones and risk of
subsequent prostate cancer (abstract). Am J Epidemiol
130(4):829, 1989.
Helzlsouer K, Gordon G, Longcope C, and Comstock GW.
Cigarette smoking and levels of endogenous hormones in
premenopausal women. Am J Epidemiol 132(4):769-770, 1990.
Mellington A, Carter B, Cohen BH, Comstock GW. Risk of
death from pneumonia and household heating sources. Am Rev
Respir Dis 141(4, part 2):A426, 1990.
Street DA, Comstock GW, Salkeld RM, Schüep W and Klag M: A
population-based case-control study of the association of
serum antioxidants and myocardial infarction (abstract).
Am J Epidemiol 134(7):719-720, 1991.
-8Bush T, Gordon G, Alberg T, Helzlsouer K and Comstock GW.
Serum dehydroepiandrosterone (DHEA) and
dehydroepiandrosterone sulfate (DHEAS) levels and risk for
ovarian cancer (abstract). Am J Epidemiol 134(7):760,
1991.
Alberg T, Bush T, Helzlsouer K and Comstock GW:
Prediagnostic serum retinol, carotenoids, vitamin E and
selenium and subsequent risk of squamous cell skin cancer
(abstract). Am J Epidemiol 134(7):764, 1991.
Scott J, Comstock GW, Hochberg M, Diamond E. Cigarette
smoking and other risk factors for hip fracture in elderly
women. Am J Epidemiol 136:977, 1992.
Scott JS, Hochberg MC, Comstock GW. Mortality after hip
fracture in community-dwelling elderly. Am J Epidemiol
138:622, 1993.
Nieto FJ, Szklo M, Comstock GW. Childhood weight as a
predictor of cardiovascular risk factors in adult
participants of the Atherosclerosis Risk in Communities
study. Am J Epidemiol 138(8):629, 1993.
Fetting JH, Comstock GW, Huelskamp A, Sullivan S, Eby S,
Piantadosi S, Kass FH, McCormack MJ, and Smith R.
Treatment for metastatic breast cancer in a defined
population: Are the elderly underserved? ASCO Annual
Meeting, May 1993.
Gordon GB, Helzlsouer KJ, Bush TL, and Comstock GW.
Dehydroepiandrosterone: A chemopreventive steroid. NCI
sponsored "Chemoprevention of Breast Cancer: Surrogate
Endpoints and Chemopreventive Agents in Short-term Clinical
Trials, October 1993.
Masi AT, Chatterton RT, Comstock GW, Malamet RL, and
Hochberg MC. Decreased androgenic-anabolic (AA) hormone
levels in sera of white women before onset of rheumatoid
arthritis: A controlled, prospective study. ACR abstract
at 57th Annual Scientific Meeting, November 1993.
"Role of Training Center for Public Health Research in
Education and Research at Johns Hopkins School of Hygiene
and Public Health" -- Health Program Alliance -- 6/28/94
Gershon RRM, Karkashian C, Burnside JF, Comstock GW.
Occupational risk of tuberculosis in funeral service
practitioners: A pilot study. SOEH abstract, 1994.
"Prevention of tuberculosis", at Tuberculosis in the
1990's: Epidemiology, Treatment, and Control. Johns
Hopkins Medical Institutions, Baltimore, 12 September 1994.
-9Wu K, Helzlsouer KJ, Alberg AJ, Norkus E, Hoffman SC,
Comstock GW. Prediagnostic ascorbic acid levels and the
risk of breast cancer. Am J Epidemiol 141(11):Suppl, June
1995.
Scott JC, Hochberg MC, Comstock GW. Questionnaire report
of functional disability is associated with hip fracture in
elderly women. Am J Epidemiol 141(11):Suppl, June 1995.
Nieto FJ, Adam E, Sorlie PD, Farzadegan H, Melnick JL,
Comstock GW. A prospective study of cytomegalovirus and
other herpes viruses as predictors of subclinical
atherosclerosis. Am J Epidemiol 141:S83, 1995.
Masi AT, Chatterton RT, Lu YC, Comstock GW, Malamet RL,
Hochberg MC, Aqodian MS, Oio-Amaize E. Low serum
dehydroepiandrosterone sulfate (DHAS) levels, rheumatoid
factor (RF) and elevated serum tumor necrosis factor α
(TNFα) without cytokine receptor (CR) elevations predict
long-term onset of RA in women: A controlled, prospective
study. Am Coll Rheumatology Poster Session, October 1995.
Arthr Rheumatol 38:S214, 1995.
Coresh J, Jaar B, Klag MJ, Whelton PK, Hoffman SC, and
Comstock GW. High blood pressure predicts the incidence of
end-stage renal disease in both men and women. Am J
Epidemiol 143:S11, 1996.
Wu K, Selhub J, Hoffman SC, Comstock GW and Helzlsouer KJ.
Serum pyridoxal-5π-phosphate (B6), B12 and folate and
consequent breast cancer risk. Am J Epidemiol 143:S87,
1996.
Shah KV, Viscidi RP, Alberg AJ, Helzlsouer KJ, Comstock GW.
Antibodies to HPV-16 capsids predict risk of future
cervical cancer. 15th International Papillomavirus
Workshop, December 1996.
"The George Comstock Address: Tuberculosis Control -Past, Present and Future", Annual Meeting, North American
Region, International Union Against Tuberculosis and Lung
Disease, 2/28/97
"Overview of Tuberculosis Epidemiology", Maryland
Tuberculosis Conference, 5/6/97
"Overview of Tuberculosis; Princeton Project 55
Tuberculosis Initiative, Baltimore, 11/1/97
Valmadrid CT, Whelton PK, West SK, Comstock GW. Isolated
systolic hypertension and seven-year risk of age-related
posterior subscapular cataract extraction: A populationbased, prospective study. ARVO abstract, 1997.
-10Scott JC, Hochberg MC, Comstock GW. Do risk factors for
trochanteric and cervical hip fractures differ? Am J
Epidemiol 145:(11)Suppl, 1997.
Masi AT, Chatterton RT, Fecht T, Aldag JC, Comstock GW,
Helzlsouer KJ, Hoffman SC, and Malamet RL. Disassociation
of serum dehydroepiandrosterone sulfate (DHEAS) and
cortisol levels in younger premenopausal women prior to
onset of rheumatoid arthritis (RA) before age 50: Results
of a prospective, controlled study. Arthritis Rheum
41:S126, 1998.
Masi AT, Chatterton RT, Aldag JC, Comstock GW, Helzlsouer
KJ, Hoffman SC, Malamet RL and Agopian MS. Decreased serum
dehydroepiandrosterone sulfate (DHEAS) levels in
menstruating women prior to onset of RA before age 50.
Independent reference laboratory assays validate previous
significant results. Arthritis Rheum 41:S126, 1998.
Masi AT, Chatterton RT, Comstock GW, Helzlsouer KJ, Hoffman
SC, Malamet RL, Sipe JD, MacCarthy K, Agopian MS, OioAmaize E. A positive history of rheumatoid arthritis (RA)
in a first degree relative (FDR) or a positive serological
predictor for RA prior to disease onset before age 50 were
uniformly present in a sample of younger premenopausal
incident cases results of a prospective, controlled study.
Arthritis Rheum 41:S126, 1998.
“Third annual T. E. Woodward Lecture: Tuberculosis— past
and present challenges.” Annual Meeting of Medical and
Chirurgical Society of Maryland, Baltimore, MD. 2 May
1998.
“Simple practical ways to assess the efficacy of a new
tuberculosis vaccine.” International Symposium on
Tuberculosis Vaccine Development and Evaluation. San
Francisco, CA. 26-28 August 1998.
“How much isoniazid is needed for prevention of
tuberculosis among immunocompetent adults?” ATS/CDC
Meeting on TB Screening and Preventive therapy, Decatur,
GA. 14-15 September 1998.
Maher D, Helzlsouer KJ, Armenian HK, Alberg AJ and Comstock
GW. Appliance use and breast cancer: A case-control
study.
SER abstract #228. Am J Epidemiol 149(11):S57,
1999.
“Why BCG Doesn’t Work — or Does It?” American Thoracic
Society International Meeting. San Diego, CA. 27 Apr
1999.
-11“Epidemiology of Tuberculosis in the U.S. at the End of the
20th Century.” Centennial Festschrift, National Jewish
Medical and Research Center, Denver, CO. 1 Oct 1999
Keynote Address: “What We Know and Don’t Know about Current
Tuberculosis Risk, and What We Need to Know to Plan
Interventions in the Future.” Tuberculosis Infection
Control in the 21st Century, Crystal City, VA. 12 Dec 1999.
“Contacts: Don’t Let the Numbers Lie: Comstock calipers
for PPD’s.” Maryland Tuberculosis Annual Meeting, Anne
Arundel County, MD. 16 Dec 1999.
Alberg A, Selhub J, Shah K, Viscidi R, Comstock G, and
Helzlsouer K. The risk of cervical cancer in relation to
serum concentrations of folate, vitamin B12, and
homocysteine. SER abstract #276. Am J Epidemiol
149(11):S69, 1999.
Helzlsouer KJ, Burke A, Hoffman S, Alberg AJ, Norkus E,
Morris S, and Comstock GW. Selenium α-tocopherol and γtocopherol and subsequent prostate cancer. SER abstract
#280. Am J Epidemiol 149(11):S70, 1999.
Masi AT, Aldag JC, Chatterton RT, Teodorescu M, Malamet RL,
Comstock GW, Helzlsouer KJ, Hoffman SC and Agopian MS.
Independent risk markers (RMs) for RA onset in males
include rheumatoid arthritis (RA) in a first degree
relative (FDR+) rheumatoid factor (RF+): combined low
serum cortisol and testosterone (low C & T), and heavy
cigarette smoking (CS 30+/d). Arthritis Rheum 43:S70,
2000.
Masi AT, Aldag JC, Pirzada FA, Pirzada N, Chatterton RT,
Malamet RL, Comstock GW, Helzlsouer KJ, Hoffman SC, Sipe
JD, and Agopian MS. Serum hormone and biological mediator
correlations were found many years before onset of
rheumatoid arthritis (RA) in 18 pre-RA males, but not in 72
matched controls (CN).
Arthritis Rheum 43:S158, 2000.
Masi AT, Aldag JC, Chatterton RT, Malamet RL, Comstock GW,
Helzlsouer KJ, Hoffman SC, Teodorescu M, Agopian MS.
Precursor risk markers (RMs) were identified in 94 percent
of 18 pre-rheumatoid arthritis (pre-RA) males compared to
28 percent of 72 matched controls (CN) in a communitybased, prospective study. Arthritis Rheum 43:S167, 2000.
“Problems with the Use of Animal Systems to Evaluate
Vaccines Against Tuberculosis”, TB Vaccine 2000 Conference,
Providence, RI, 3 November 2000.
-12Discussant, “Occupational Exposure to Tuberculosis:
Evidence Review”, Institute of Medicine Workshop on
Regulation. Occupational Exposure to Tuberculosis,
Washington, DC, 8 August 2000.
Congress of Epidemiology, 2001
Sato R, Alberg AJ, Hoffman SC, Comstock GW, Helzlsouer KJ.
Physical activity in older adults: Are guidelines being
followed?
Hoffman SC, Burke AE, Comstock GW, Helzlsouer KJ. Is body
mass index (BMI) at age 21 predictive of the development of
type 2 diabetes later in life?
Huang H-Y, Alberg AJ, Hoffman SC, Appel LJ, Comstock GW,
Helzlsouer KJ. From clinical trials to the general
population:
Use of aspirin in the prevention of
cardiovascular disease.
Newschaffer CJ, Sato R, Comstock GW, Helzlsouer KJ.
Conservation of specimen bank resources:
Application of
early stopping approaches to nested case-control studies in
the CLUE cohort.
Comstock GW.
BCG: A review. Northeastern Tuberculosis
Controllers Annual Meeting, Ocean City, MD, Oct. 11, 2001.
Invited Seminars:
"Epidemiology of Tuberculosis", Frontiers of Research and
Clinical Management of Asthma and Allergy, Francis Scott
Key Hospital, Baltimore, 1/19/97
"Tuberculosis", School of Medicine, Johns Hopkins
University, 1/29/97
"Epidemiology of Tuberculosis in the '90's and Beyond",
Maryland Tuberculosis Today Meeting, 10/7/97
“Tuberculosis Update.” Staff Meeting, Frederick Memorial
Hospital, Frederick MD. 6 Mar 1998.
“Epidemiology of tuberculosis in the ‘90's and beyond.”
Maryland TB Today Course, Mariottesville, MD. 5 May 1998.
“Historical perspectives of tuberculosis.” Annual Meeting
of Mycobacterium Tuberculosis Study Support Program,
Bethesda, MD. 20 October 1998.
-13“Tuberculosis Update.”
Western Maryland Center,
Hagerstown, MD. 22 October 1998.
“Fifty years of public health: Local health department
policies and practices in the 1940's and 1990's.”
Washington County Health Department Staff Development Day,
Clear Spring, MD. 23 October 1998.
“History of Tuberculosis Control.” World TB Day, A. G.
Holley State Hospital, Lantana, FL. 24 Mar 1999.
“Epidemiology of Tuberculosis.” Maryland TB Today.
Mariottsville, MD. 11 May 1999.
“Tuberculosis”, Introduction to Epidemiology, Homewood
Campus, 5 January 2000.
“BCG Vaccination”, Department of Preventive Medicine
seminar, University of Maryland, 27 Jan 2000.
“Epidemiology of Tuberculosis”, TB Today, Maryland
Department of Health and Mental Hygiene, Marriottsville,
MD, 26 Apr 2000.
“Influenza”, Advisory Commission to the Washington County
Health Department, Hagerstown, MD, 8 May 2000.
“Overview of BCG Trials”, Clinical Trials Seminar, 1 Nov
2000.
“Epidemiology of Tuberculosis”, Clinical Fellows Seminar,
Bayview Campus, 17 Nov 2000.
Epidemiology of Tuberculosis, Maryland TB Today,
Marriottsville, MD, 24 April 01
Epidemiology of Tuberculosis, Maryland TB Today,
Marriottsville, MD, 13 April 02.
“Tuberculosis as a World-wide Problem”, Homewood
Intersession Course, 1/17/02.
“TB Today”, Maryland Department of Health and Mental
Hygiene, 4/23/02.
-14ADDITIONAL INFORMATION
Research interests and objectives:
Although I seem to be generally associated with
tuberculosis, a review of my publications will show that my
research interests have been very broad. The common thread
through most of these studies has been that they are based on
local communities— Muscogee county, GA; Bethel area of Alaska;
and Washington County, MD.
During the past 30 years, a major part of my research has
dealt with the relationships of serum or plasma concentrations of
micronutrients, hormones, and viral antibodies to the subsequent
development of cancer. More recently, the interactions of gene
and environmental characteristics have been a major focus. I
have also been concerned with some of the elementary (but
ignored) problems of long-term storage of biologic specimens—
temperature variation within freezers, changes on concentrations
of analytes with prolonged storage, and the degree of agreement
of analyte concentrations in specimens from the same individual
separated by years of storage.
Another major portion of my research has been collaboration
in studies of cardiovascular outcomes associated with serologic
and clinical characteristics determined years earlier.
Specifically, this has involved linkage of records from the
Washington County portions of ARIC (Atherosclerosis Risk in
Communities) and CHS (Cardiovascular Health Study) with records
from our two big blood collection projects, CLUE I and CLUE II.
The combination is a unique resource.
Keywords:
Atherosclerosis, Biological Markers, Epidemiologic
Methods, Micronutrients, Neoplasms, Tuberculosis.