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B.Pharm III (Third) Semester Examination 2011-12
Course Code:BPH304
Paper ID:0953104
Pharmaceutical Organic Chemistry-II
Time: 3 Hours
Max. Marks: 70
Note: Attempt six questions in all. Q. No. 1 is compulsory.
1.
a)
b)
c)
d)
e)
f)
g)
h)
Answer any five of the following (limit your answer to 50
words).
(4x5=20)
Write about ketonic hydrolysis of acetoacetic ester.
On basis of which two chemical properties Malonic ester is
used as a synthetic reagent?
Draw structure of Guanine.
Define frie’s reaction.
Define Witting reaction.
Which name reaction describes synthesis of ketone from
secondary alcohol? Name refluxing agents and bases used in
this reaction.
Classify amino acids with examples.
In furan, substitution at 2-position is favoured. Why?
2.
Write general methods of synthesis of amino acids with one
example in each method. Write various reactions of amino
acids due to Amino group.
(10)
3.
Define Mannich reaction and Benzoin condensation along
with their mechanism.
(10)
4.
Write synthetic applications of Merwin Pondorff Verley
reduction and Oppeneaur oxidation with examples.
(10)
5.
Write methods of preparation and reactions of Methyl vinyl
ketone. Write synthetic applications of Malonic easter. (10)
6.
Classify proteins with example.
identification tests of proteins.
Describe
various
(5)
7.
Write definition, mechanism and applications of Michael
condensation.
(5)
8.
Write methods of preparation and properties of Pyridine and
Indole.
(5)