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9.3 & 9.4 Reinforcement Questions Name: ________________________ 1. What are anabolic steroids and why were they developed? 2. What are the two phases in forensic scientist’s analytical scheme? 3. What is the difference between a screening test and a confirmation test? 4. Name two types of empirical tests used to identify drugs. Why are these tests referred to as empirical? 5. Why is chromatography particularly well suited to the needs of a drug analyst? 6. In chromatography, the distribution of a gas between the liquid and gas phases is determined by: a. The density of the gas relative to the liquid b. The volume of the gas in the container c. The solubility of gas in the liquid d. The mass of the gas relative to the liquid 7. Explain how chromatography is like a race between chemical compounds. 8. Name three distinct advantages of gas chromatography in the ID of drugs. 9. What is the main drawback of gas chromatography in the ID of drugs? 10. What phenomenon forms the basis of spectrophotometry? 11. What is the main advantage of infrared spectrophotometry over ultraviolet or visible-light spectrophotometry? 12. With what analytical device is a gas chromatography often connect to analyze drug mixtures and why? 9.3 Reinforcement Questions Answers 1. What are anabolic steroids and why were they developed? 4pts Synthetic compounds that are chemically related to testosterone. Developed to promote muscle growth while avoiding androgenic effects 2. What are the two phases in forensic scientist’s analytical scheme? 2pts Screening and confirmation 3. What is the difference between a screening test and a confirmation test? 3pts Screening reduces the number of substances possible while confirmation identifies the presence of a specific substance in an unknown sample. 4. Name two types of empirical tests used to identify drugs. Why are these tests referred to as empirical 3pts Color test and microcrystalline. Tests are accurate but scientists do not understand why such tests produce their results. 5. Why is chromatography particularly well suited to the needs of a drug analyst? 2pts Separate unknown mixtures into their components. Useful for analyzing drug specimens because drugs may be diluted with anything 6. In chromatography, the distribution of a gas between the liquid and gas phases is determined 7. 8. 9. 10. 11. 12. by: C1pt Explain how chromatography is like a race between chemical compounds. 2pts The materials that prefer the moving phase slowly pull ahead of those that prefer to remain in the stationary phase Name three distinct advantages of gas chromatography in the ID of drugs. 3pts Resolves a highly complex mixture into component parts, extremely sensitive, yields quantitative results What is the main drawback of gas chromatography in the ID of drugs? 1pt Several substances may have the same retention time What phenomenon forms the basis of spectrophotometry? 1pt Substances can absorb invisible electromagnetic radiation What is the main advantage of infrared spectrophotometry over ultraviolet or visible-light spectrophotometry? 2pts IR is more definitive and can provide definite ID With what analytical device is a gas chromatography often connect to analyze drug mixtures and why? 2pts MS to positively ID substances separated from a mix by the GC