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Provided by: Tracie Schroeder; modified by Michel Skinner Human Pedigree Name __________________________ A diagram showing the transmission of a trait through several generations of a family is called a pedigree. In Figure 1, generation I is made up of grandparents, generation II is their children, and generation III is their grandchildren. Study the pedigree diagram in Figure 1 to learn the symbols. Female without trait Male without trait Female with trait Male with trait Female, died in infancy Male, died in infancy Identical twins FIGURE 1 I 1 2 II 1 III 2 3 4 1 2 5 3 Provided by: Tracie Schroeder; modified by Michel Skinner Individuals who lack an enzyme needed to form the skin pigment melanin are called albinos. Normal skin pigmentation is dominant. Use D to represent the gene for normal skin and dd to represent the genotype for albinism. Where you cannot be sure whether an individual with the dominant trait is heterozygous or homozygous, show the genotype as D-. FIGURE 2 Genotype I 1 ________ 2 ________ 3 ________ 4 ________ II 1 ________ 2 ________ 3 ________ 4 ________ 5 ________ 6 ________ 7 ________ III 1 ________ 2 ________ 1. In the pedigree above, if individuals 6 and 7 have another child, what is the chance that it will be an albino? ____________________________________________________________ 2. Are individuals 1 and 2 in generation I homozygous or heterozygous? Explain. ______________________________________________________________________________ 3. What gender is individual 3 of generation II? ____________________ 4. What relationship do individuals 6 & 7 of generation II share? _____________________________ 5. If Individual 2 of generation III married a man who was homozygous for normal skin, what would be the probability of them having an albino child? _________________ What chance do they have of having a girl? _____________ Draw their daughter in the pedigree. Provided by: Tracie Schroeder; modified by Michel Skinner Individuals who can taste the chemical phenylthiocarbamide, PTC, have the dominant gene, A. Those with the recessive genes, aa, cannot taste it. Remember: People with the trait are shaded. Use “A” to represent the gene for a PTC taster, a dominant trait. Use “aa” for the PTC nontaster, the recessive trait. FIGURE 3 Genotype 1 ________ 2 ________ 3 ________ 4 ________ II 1 ________ 2 ________ 3 ________ 4 ________ 5 ________ 6 ________ 7 ________ 8 ________ III 1 ________ 2 ________ 3 ________ 4 ________ I 1. In the pedigree above, if individuals 4 and 5 in generation II have another child, what is the probability that it will be a taster? _______________________________________ 2. If individual 8 in generation II married a man with genotype AA, what is the probability that she will have a non-taster child? _____________________________________ 3. What relationship do individuals 4 & 5 of generation 2 from Figure 3 have? ________________ Homework: On a separate sheet of paper: Construct a pedigree diagram of your family for one of the traits listed below. Pick a trait that is not found in all the members of your family. List as many genotypes as possible. It should include your grandparents, parents and siblings. (3 generations) Tongue rolling: Dominant trait; Non tongue rolling: recessive trait Hitchhikers thumb: recessive trait; straight thumb: Dominant trait Widow’s peak: Dominant trait; straight hairline: recessive trait Attached earlobe: recessive trait; Free hanging earlobe: Dominant trait Dimples: Dominant trait; lack of dimples: recessive trait Provided by: Tracie Schroeder; modified by Michel Skinner The Ultimate Pedigree Challenge Is it possible for someone to be his own grandpa? This story is actually a song written by Dwight Latham and Moe Jaffe (1947, General Music Publishing Company, Inc.) Read the story (sing along if you dare) and draw the pedigree of this man's family. GOOD LUCK! Many, many years ago when I was twenty-three I was married to a widow who was pretty as could be. This widow had a grown-up daughter who had hair of red. My father fell in love with her and soon the two were wed. This made my dad my son-in-law and changed my very life For my daughter was my mother, 'cause she was my father's wife. To complicate the matter even though it brought me joy I soon became the father of a bouncing baby boy. My little baby then became a brother-in-law to dad And so he became my uncle though it made me very sad For if he is my uncle then that also makes him brother, To the widow's lovely daughter who, of course, was my step-mother. Father's wife then had a child which kept them on the run, And he became my grandchild, 'cause he was my daughter's son; My wife she is my mother's mother and it makes me blue, Because although she is my wife, she's my grandmother too. Now if she is my grandmother than I'm her grandchild And every time I think of it, it nearly drives me wild; For now I have become the strangest case you ever saw As husband of my grandmother I am my own grandpa. Chorus: Oh, I'm my own grandpa, I'm my own grandpa It sounds funny, I know, but it really is so Oh, I'm my own grandpa. Now see if you can create a pedigree for the narrator’s family!