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BSC 2010 (Ellington) Practice Exam2- KEY 1. Biological membranes can be described as a “solution” of ___________ “dissolved” in _________. (A) proteins, phospholipids, (B) phospholipids, proteins, (C) inorganic ions, phospholipids, (D) simple sugars, phospholipids or (E) none of the above. 2. In the cytoskeleton, actin subunits form ____________. (A) microtubules, (B) microfilaments, (C) intermediate filaments, (D) micelles or (E) none of the above. 3. Which of the following is NOT an organelle? (A) mitochondrion, (B) chloroplast, (C) lysosome, (D) peroxisome or (E) nucleoid. 4. Which of the following is NOT present dissolved in the cytosol of cells? (A) Na+, (B) Cl-, (C) K+, (D) all of the above, or (E) none of the above. 5. In eukaryotic cells protein synthesis takes place in __________. (A) vacuoles, (B) lysosomes, (C) smooth ER, (D) rough ER, or (E) peroxisomes. 6. A peripheral protein in a cell membrane _____________________. (A) interacts with the hydrophobic interior of the membrane, (B) passes all the way through the membrane, (C) interacts with the charged surface of the membrane, (D) does not interact with the membrane or (E) none of the above. 7. The surface of a cell membrane _________________. (A) is highly polar and charged, (B) interacts with water, (C) is primarily composed of the hydrophilic “heads” of phospholipids, (D) all of the above or (E) none of the above. 8. A reaction is spontaneous when ________. (A) entropy is increased, (B) free energy is increased, (C) both free energy and entropy are increased, (D) both free energy and entropy are decreased or (E) entropy is decreased. 9. Which of the following Keq values would correspond to that of a highly spontaneous reaction? (A) 0.005, (B) 1, (C) 1,000, (D) 3 or (E) 0.0001 10. In living cells you would find that __________. (A) [ADP] <<< [ATP], (B) [ADP] >>> [ATP], (C) [ADP] + [ATP] <<< [inorganic phosphate], (D) [ADP] = [ATP] or (E) none of the above. 11. An enzyme ______________. (A) is typically a protein, (B) reduces the activation energy of a reaction, (C) is typically sensitive to pH and temperature changes in its environment, (D) all of the above or (E) none of the above. 12. An enzyme with a higher Km value than another enzyme ____________. (A) will have a higher affinity for substrate, (B) will show a higher velocity at low 1 [substrate], (C) will have a higher Vmax, (D) all of the above or (E) none of the above. 13. A __________ is likely going to be the most permeable substance across a phospholipid bilayer. (A) protein, (B) sodium ion, (C) glycogen molecule, (D) water molecule or (E) polar amino acid. 14. To maximize the rate of passive diffusion of a lipid soluble substance across a phospholipid bilayer one must________________. (A) increase P, decrease C, increase A, (B) decrease P, decrease C, decrease A, (C) increase P, increase C, increase A, (D) decrease P, increase C, decrease A or (E) increase P, decrease C, decrease A. 15. If a cell is placed in a hypo-tonic medium _____________. (A) it will shrink in volume, (B) it will swell in volume, (C) it will lose water, (D) A and B but not C or (E) A and C but not B. 16. A beaker containing a 0.1 M solution of sucrose is _____________ with respect to a beaker containing 0.3 M sucrose. (A) hypo-tonic, (B) hyper-tonic, (C) hypoosmotic, (D) hyper-osmotic, or (E) isosmotic. 17. In active transport _____________. (A) substances are transported uphill, (B) substances are transported from an area of low concentration to an area of high concentration, (C) involves the action of a membrane proteins, (D) is typically directly or indirectly coupled to ATP hydrolysis or (E) all of the above. 18. Anabolic pathways _____________. (A) break down macromolecules, (B) produce ATP, (C) are spontaneous and do not require ATP input, (D) all of the above or (E) none of the above. 19. In a redox reaction _____________. (A) electrons flow from a less electronegative to a more electronegative substance, (B) the oxidant receives electrons, (C) the substance that is reduced receives electrons, (D) all of the above or (E) none of the above. 20. A atom which is very electronegative ____________. (A) is inert, (B) readily donates electrons, (C) readily accepts electrons, (D) neither accepts or donates electrons or (E) none of the above. 21. NADH is ____________. (A) an oxidized form of a coenzyme, (B) is the oxidant in many biological redox reactions, (C) receives electrons in redox reactions, (D) all of the above or (E) none of the above. 22. Which of the following is (are) NOT true about substrate level phosphorylations? (A) produced by proton gradients, (B) occur in reactions that 2 have a positive G, (C) produce more ATP in the mitochondria than oxidative phosphorylation, (D) all of the above or (E) none of the above. 3