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AP Biology Korzeniewski Name___________________________ Date__________________Per_______ Cell Cycle Unit – PDQ’s 1-4 Cells 1 – Mitosis Due Date: ____________________ Stamp: _________________ Textbook Reading: Ch. 12 Presentation Prezi: Cell Cycle 1: Mitosis Supplementary Resources: Crash Course Biology o Mitosis- Splitting Up is Complicated: Biology #12 Bozeman’s Science: Paul Anderson: o Cell Cycle, Mitosis and Meiosis o Mitosis Big Questions: Why does life require cells? How are cells organized? What is the advantage to having organelles? How do the interactions of cellular components allow for life processes? Questions to Answer: 1. What has to occur for a cell to divide? What purposes do these divisions serve? 2. Why does the DNA condense into chromosomes during cell division? 3. Explain what happens during each of the following phases of the cell cycle in a typical eukaryotic cell: 1. Interphase i. G1 ii. S iii. G2 2. Prophase 3. Pro-Metaphase 4. Metaphase 5. Anaphase 6. Telophase 7. Cytokinesis 4. What is different about cytokinesis in animal-like cells as compared to plant-like cells? 5. If a cell has 12 pairs of chromosomes in G1 of interphase, how many chromosomes does it have during each of the following phases of the cell cycle? 1. G2 2. Metaphase 3. Immediately after cytokinesis 6. Briefly discuss the evolutionary trend in mitosis shown in the protists . Things you should make sure you understand: The differences between prokaryotic, and eukaryotic cell division The following terms as relate to DNA structures: Â chromosome, chromatid, centromere. How chromosomes migrate during cell division. The evolutionary trends in cell division, demonstrated by different members of the protist taxon Cells 2 – Cell Cycle Control Due Date: ____________________ Stamp: _________________ Textbook Reading: Ch. 12 Presentation Prezi: Cell Cycle 2: Cell Cycle Control Supplementary Resources: Crash Course Biology o Mitosis- Splitting Up is Complicated: Biology #12 Bozeman’s Science: Paul Anderson: o Cell Cycle, Mitosis and Meiosis Big Questions: How is cell division controlled? Why do people get cancer? Questions to Answer: 1. Why does a multicellular organism need to control and coordinate cell division? What might be the consequences of uncontrolled cell division in a multicellular organism? 2. What does it mean when we say that there are several “checkpoints” that occur during the cell cycle? 3. What are the “Questions” that a cell must “answer” during each of the following checkpoints: 1. G1/S checkpoint 2. G2 checkpoint 3. spindle checkpoint 4. Diagram the relationship between cdK, and cyclin. 5. Give an example of an external signal that regulates cell division and explain how it works. 6. Compare and contrast the functions of proto-oncogenes and tumor suppressor genes. Give an example of each and explain why mutations in these genes can lead to cancer. Cells 3 – Meiosis Due Date: ____________________ Stamp: _________________ Textbook Reading: Ch. 13 Presentation Prezi: Cell Cycle 3: Meiosis Supplementary Resources: Crash Course Biology Meiosis- Where the Sex Starts: Biology #13 Bozeman’s Science: Paul Anderson: o Cell Cycle, Mitosis and Meiosis o Meiosis o Mechanisms that Increase Genetic Variation Big Questions: How is sex possible? Why does sex exist? Where does variation in a population come from? Questions to Answer: 1. Explain how asexual reproduction is different from sexual reproduction. 2. Explain what happens during crossing over and when it occurs in meiosis. 3. How is metaphase I different from metaphase of mitosis? 4. Explain why sexual reproduction increases variation among offspring much more than asexual reproduction does. 5. How many possible genetic variations can be produced during meiosis and sexual reproduction? 6. How is sexual reproduction related to gender determination in mammals? 7. If the progenitor cell of a gamete has 12 pairs of chromosomes during G1 of interphase, how many chromosomes will the following cells have? 1. after S phase of interphase. 2. a daughter cell immediately following cytokinesis I of meiosis. 3. a daughter cell during anaphase II of meiosis. 4. a daughter cell immediately following cytokinesis II of meiosis. Things you should make sure you understand: The differences in sexual life cycles shown in plants, fungi, and animals. The relationship between homologous pairs of chromosomes. How meiosis evolved and why it bears a strong resemblance to mitosis. The major differences between mitosis and meiosis. The process of karyotyping and why/when it is used Cells 4 – Chromosomal Abnormalities Due Date: ____________________ Stamp: _________________ Textbook Reading: Ch. 13 Presentation Prezi: Cell Cycle 4: Chromosomal Abnormalities Supplementary Resources: Crash Course Biology Meiosis- Where the Sex Starts: Biology #13 Big Questions: How can genetic material be changed? How do changes in the genetic material of an organism lead to changes in traits of the organism? Questions to Answer: 1. Define “non-disjunction”. Why can this be a problem during meiosis? 2. How is Down’s Syndrome diagnosed? 3. Why is having an extra Chromosome 21 tolerable to the point that someone with this condition can survive to maturity? 4. Why is having an extra Chromosome 21 deleterious to the person who has this condition? 5. Compare and contrast the following chromosomal syndromes: 1. Kleinfelter’s Syndrome 2. Jacob’s Syndrome 3. Trisomy X 4. Turner’s Syndrome 6. Explain what happens during each of the following chromosomal mutations: 1. Deletion 2. Duplication 3. Inversion 4. Translocation Things you should make sure you understand: (feel free to ask questions about them in class) 1. The causes and effects of all of the abnormalities discussed in this presentation.