Download DRUG NAME - Nursing Crib

DRUG NAME
Ibuprofen

Advil, ApoIbuprofen,
Motrin,
Excedrin IB,
Genpril,
Haltran, Ibutab,
Medipren,
Menadol,
Midol IB,
Motrin,
Rufen,
Trendar.
DOSAGE AND
ROUTE
Rheumatoid
arthritis,
osteoarthritis,
arthritis
 Adult: 300 to
800 mg P.O.
t.i.d. or q.i.d.
Maximum
daily dose is
3.2 g.
Mild to
moderate pain,
dysmenorrheal
 Adult: 400
mg P.O. q 4
to 6 hours,
p.r.n.
Fever
 Adults: 200 to
400 mg. P.O.
q 4 to 6
hours, for no
longer than 3
days.
Maximum
daily dose
is1.2 g.
 Children
ages 6
months to 12
years; If
child’s
temperature
is below
102.5º F
(39.2 ºC),
give 5 mg/kg
P.O. q 6 to 8
hours. Treat
ACTION
INDICATION
ADVERSE
EFFECTS
Unknown. May
inhibit
prostaglandin
synthesis, to
produce antiinflammatory,
analgesic, and
antipyretic
effects.
Ibuprofen contains
the active ingredient
ibuprofen, which
belongs to a group of
medicines called
non-steroidal antiinflammatory drugs
(NSAIDs).
It works by blocking
the action of a
substance in the
body called cyclooxygenase. Cyclooxygenase is
involved in the
production of various
chemicals in the
body, some of which
are known as
prostaglandins.
Prostaglandins are
produced in response
to injury or certain
diseases and would
otherwise go on to
cause pain, swelling
and inflammation.
Ibuprofen is
therefore used to
relieve pain and
inflammation.
All the medicines in
this group (NSAIDs)
reduce inflammation
caused by the body's
own immune system,
and are effective pain
killers. Ibuprofen can
be used to relieve
CNS
 Headache,
dizziness,
nervousness,
aseptic
meningitis.
CV
 Peripheral
edema, fluid
retention,
edema.
EENT
 Tinnitus
GI
 Epigastric
distress,
nausea, occult
blood loss,
peptic
ulceration,
diarrhea,
constipation,
abdominal
pain, bloating,
GI fullness,
dyspepsia,
flatulence,
heartburn,
decreased
appetite.
GU
 Acute renal
failure,
azotemia,
cystitis,
hematuria.
HEMATOLOGIC
 Plonged
bleeding time,
NURSING
RESPONSIBILITY
CONTRAINDICATION



Contraindicated in
patients hypersensitive
to drug and in those
with angioedema,
syndrome of nasal
polyps, or
bronchospastic reaction
to aspirin or other
NSAIDs.
Contraindicated in
pregnant women.
Use cautiously in
patients with GI
disorders, history of
peptic ulcer disease,
cardiac
decompensation,
hypertension, asthma,
or intrinsic coagulation
defects.





Tell patient to take
with meals or milk to
reduce adverse GI
reactions.
Note: Drug is
available at OTC.
Instruct patient not to
exceed 1.2 g daily,
not to give to chidren
younger than age 12,
and not to take for
extended periods (
longer than 3 days
for fever or longer
than 10 days for
pain) without
consulting presciber.
Tell patient that full
therapeutic effect for
arthritis may be
delayed for 2 to 4
weeks. Although pain
relief occurs at low
dosage levels,
inflammation doesn’t
improve at dosages
less than 400 mg
q.i.d.
Teach patient to
watch for and report
to prescriber
immediately signs
and symptoms of GI
bleeding, including
blood in vomit, urine,
or stool or coffee
ground vomit, and
black, tarry stool.
Warn patient to avoid
higher
temperatures
with 10mg/kg
q to 6 hours.
Maximum
daily dose in
40mg/kg.
Juvenile
arthritis
 Children: 30
to 40 mg/kg
daily P.O. in
three or four
divided
doses.
Maximum
daily dose is
50 mg/kg.
M /I
pain such as
muscular aches and
pains, period pains,
headache,
backache,
rheumatic pain,
dental pain and
neuralgia. It can also
reduce feverishness
and the symptoms of
colds and flu.
anemia,
neutropenia,
pancytopenia,
thrombocytope
nia, aplastic
anemia,
leucopenia,
agranulocystoci
s.
METABOLIC
 Hypoglycemia,
hyperkalemia.
RESPIRATORY:
 Bronchospasm
SKIN
 Pruritus, rash,
urticaria,
stevens
Johnson
syndrome.

hazardous activities
that require mental
alertness until effects
on CNS are known.
Advise patient to
wear sunscreen to
avoid hypersensitivity
to sunlight.