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Punnett Squares: All types
1. Hemophilia is a sex-linked recessive disorder. What is the likelihood that a
Female who is a carrier for hemophilia marries a normal man will have a
hemophiliac son?
2. Alkaptonuria, or black urine disease results from a recessive gene. A man who is
homozygous dominant and a woman who is homozygous recessive marry. What
is the chance their child will have the disease?
3. Wolves are sometimes observed to have black coats and blue eyes. Normal coat
color (N) is dominant to black (n) and brown eyes (B) are dominant to blue (b).
Suppose the male is black with blue eyes and the female is heterozygous for both
traits. List all possible genotypes and phenotypes the offspring could have.
4. Suppose dwarf plants are recessive to Tall plants. If a plant that is heterozygous
is mated with a dwarfed plant, what is the chance the f1 generation will be tall?
5. Carrion beetles lay their eggs in dead animals and then bury them in the ground
until they hatch. Assume that the preference for fresh meat (F) is dominant to the
preference for rotted meat and that the tendency to bury the meat shallow (S) is
dominant to the tendency to bury the meat deep. Suppose a female carrion beetle
homozygous dominant for both traits mates with a male homozygous recessive
for both traits. What will be the genotypes and phenotypes be for the f1
generation?
6. Duchenne Muscular Dystrophy is a sex-linked recessive disorder. If a woman
who is homozygous dominant has children with a man who has Muscular
Dystrophy, what is the chance that they will have normal males and females?
7. Suppose in a strain of soybeans, high oil (H) content in the seeds is dominant to
low oil content and four seeds (E) in a pod is dominant to two seeds in a pod. A
farmer crosses two soybean plants, both with high oil content and four seeds per
pod. The resulting F1 offspring have a phenotypic ratio of 9:3:3:1 (High oil / four
seeds : High oil / two seeds : Low oil / four seeds : Low oil / two seeds). What
genotype were the parent plants? Show your punnett square for support.
8. Fragile-X Syndrome: A rare sex-linked inherited disease characterized by
various physical anomalies as well as mental retardation . Suppose a normal
female and a male who has fragile x syndrome have children. What is the
likliehood their children will have the disease? Will be normal? (you may need to
show more than 1 punnett square)
9. Pod shape smooth (N) constricted (n), pod color green (G) yellow (g) What are
the genotypic and phenotypic ratios in the offspring resulting from a cross
between two pea plants that are heterozygous for pod color and pod shape?
Blood Typing
10. Explain why someone with Type O blood can donate to all ABO blood types but
can only receive Type O blood.
11. A man is trying to establish his paternity for a child. His blood type is B+
(genotype B+B+). The child is type B-. Could he be the father? Why or why
not?
12. A man who is A+ marries a woman who is B-. What are all possible genotypes
of their children.
Pedigrees
13. Albinism is a disease that causes people to lack pigmentation. Kelly and Mike are
normal for pigmentation and have two children Jake and Jane, both are normal.
Jane marries John who is normal. John’s two sisters are also normal and their
parents are normal. Jane and John have three children Jessica who is normal and
Jackie who is albino. They also have a son, Jonah, who is albino.
a. Draw the pedigree
b. Is it a sex-linked trait? Explain your answer
c. Is it a dominant trait? Explain your answer
d. Label the genotypes
13-14 Below are two different pedigrees. Label the genotypes as well as telling me
the following info for each pedigree.
a. Is it a sex-linked trait? Explain your answer
b. Is it a dominant trait? Explain your answer