EEG Gamma Power Changes Following Administration of NMDA
... Plots showing average fold-change in the γ frequency band power 90 minutes following drug administration as a function of Cmax (Left, ketamine; Right; traxoprodil) Clinical ranges were simulated or quoted from listed references. ...
... Plots showing average fold-change in the γ frequency band power 90 minutes following drug administration as a function of Cmax (Left, ketamine; Right; traxoprodil) Clinical ranges were simulated or quoted from listed references. ...
Pharmacokinetic & Pharmacodynamic of Ketamine in Pediatric
... Used as dissociative anesthetic It is commercially available as racemic mixture of two enantiomers R(-)ketamine and S(+)-ketamine. ...
... Used as dissociative anesthetic It is commercially available as racemic mixture of two enantiomers R(-)ketamine and S(+)-ketamine. ...
2015 Ketamine Rescheduling
... international regulation of ketamine that would result in this drug being more difficult, if not impossible, to obtain by licensed veterinarians for the authorized treatment of animals. The AAZV is the professional association for veterinarians and institutions that focus on the medical care of zoo ...
... international regulation of ketamine that would result in this drug being more difficult, if not impossible, to obtain by licensed veterinarians for the authorized treatment of animals. The AAZV is the professional association for veterinarians and institutions that focus on the medical care of zoo ...
Ketamine
... Like other drugs of this class such as phencyclidine (PCP), Ketamine induces a state referred to as *“Dissociative Anesthesia” and is used as a recreational drug Ketamine has a wide range of effects in humans, including: Anesthesia - ‘blocking sensations’ inc. pain Analgesia - specific painkil ...
... Like other drugs of this class such as phencyclidine (PCP), Ketamine induces a state referred to as *“Dissociative Anesthesia” and is used as a recreational drug Ketamine has a wide range of effects in humans, including: Anesthesia - ‘blocking sensations’ inc. pain Analgesia - specific painkil ...
A1984SU44500001
... on the clinical pharmacologic effects of CI-581 in man, now better known as ketamine, is certainly such an example for me. Twenty years ago a series of events culminated in a request by Alex Lane, then at Parke Davis, that I study the clinical pharmacology of a new chemical which had never been give ...
... on the clinical pharmacologic effects of CI-581 in man, now better known as ketamine, is certainly such an example for me. Twenty years ago a series of events culminated in a request by Alex Lane, then at Parke Davis, that I study the clinical pharmacology of a new chemical which had never been give ...
Re: Docket No. FDA-2015-N-0045 for International Drug Scheduling
... illegal or unauthorized use. A change to this status would have deleterious impacts in clinical and research settings, where ketamine is approved as an anesthetic both for humans and animals. Ketamine is used for sedation and analgesia in clinical veterinary practice as well as in animal research. B ...
... illegal or unauthorized use. A change to this status would have deleterious impacts in clinical and research settings, where ketamine is approved as an anesthetic both for humans and animals. Ketamine is used for sedation and analgesia in clinical veterinary practice as well as in animal research. B ...
Ketamine
Ketamine (INN) is a medication used mainly for starting and maintaining anesthesia. Other uses include sedation in intensive care, as a pain killer, as treatment of bronchospasm, as a treatment for complex regional pain syndrome and as an antidepressant. It induces a trance-like state while providing pain relief, sedation, and memory loss. Heart function, breathing, and airway reflexes generally remain functional.Common side effects include psychological reactions as the medication wears off. These reactions may include agitation, confusion, or psychosis. Elevated blood pressure and muscle tremors are relatively common, while low blood pressure and a decrease in breathing is less so. Spasms of the larynx may rarely occur.Pharmacologically, ketamine is classified as an NMDA receptor antagonist, but it also acts at numerous other sites (including opioid receptors and monoamine transporters). Like other drugs of the arylcyclohexylamine class, such as phencyclidine (PCP), ketamine is classified as a dissociative agent.Ketamine was first developed in 1962. It is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system. It is legally sold under a very wide variety of brand names, including Ketalar. Ketamine's use as a recreational drug has been implicated in a number of annual deaths.