Myocardial stress and hypertrophy - Journal of Clinical Investigation
... In concentric LV remodeling, the contribution of LV hypertrophy to the prevailing LV wall stress remains clinically relevant. It is still debated whether asymptomatic patients with extensive LV hypertrophy should undergo aortic valve replacement to prevent progression of LV hypertrophy or whether th ...
... In concentric LV remodeling, the contribution of LV hypertrophy to the prevailing LV wall stress remains clinically relevant. It is still debated whether asymptomatic patients with extensive LV hypertrophy should undergo aortic valve replacement to prevent progression of LV hypertrophy or whether th ...
the mechanism of the nervous regulation of the crayfish heart
... normally starts beating immediately after the end of stimulation, usually at a frequency slower than normal, speeding up rather gradually (PI. 1, fig. 1:60). This after-effect will be discussed in more detail later. Variation in stimulus strength at a frequency which causes complete inhibition shows ...
... normally starts beating immediately after the end of stimulation, usually at a frequency slower than normal, speeding up rather gradually (PI. 1, fig. 1:60). This after-effect will be discussed in more detail later. Variation in stimulus strength at a frequency which causes complete inhibition shows ...
Electrocardiographic Manifestations of Hypothermia
... diabetes mellitus was brought to the ED by paramedics from her family’s home for evaluation of a decreased level of consciousness. Family members found her in bed unarousable. She had last been seen 10 hours earlier at nighttime, and she appeared normal at that time. The only medications she took, a ...
... diabetes mellitus was brought to the ED by paramedics from her family’s home for evaluation of a decreased level of consciousness. Family members found her in bed unarousable. She had last been seen 10 hours earlier at nighttime, and she appeared normal at that time. The only medications she took, a ...
Transesophageal echocardiography in the OR and ICU
... severe cardiac dysfunction, either systolic or diastolic, and echocardiography can detect the cardiac performance, assessing both systolic and/or diastolic impairment.51 In patients with acute unexplained hypotension and suboptimal TTE images due to mechanical ventilation, surgical wounds, medicatio ...
... severe cardiac dysfunction, either systolic or diastolic, and echocardiography can detect the cardiac performance, assessing both systolic and/or diastolic impairment.51 In patients with acute unexplained hypotension and suboptimal TTE images due to mechanical ventilation, surgical wounds, medicatio ...
- highlights for sports medicine from the European
... in SCA may have agonal breathing patterns (occasional gasps, slow, laboured or noisy breathing) in the first few minutes after SCA and resuscitation initiated when this is present is associated with higher survival rates.6 Additionally, seizure-like movements of the limbs within the first few minutes ...
... in SCA may have agonal breathing patterns (occasional gasps, slow, laboured or noisy breathing) in the first few minutes after SCA and resuscitation initiated when this is present is associated with higher survival rates.6 Additionally, seizure-like movements of the limbs within the first few minutes ...
Surrogate Measures of Arterial Stiffness
... For instance, although brachial PP and aortic PWV are strongly linked, they represent 2 aspects of hemodynamics. Pulse pressure increases when aortic stiffness increases because the pressure wave, which travels from the heart to the periphery (during each cardiac cycle), is reflected at some point, ...
... For instance, although brachial PP and aortic PWV are strongly linked, they represent 2 aspects of hemodynamics. Pulse pressure increases when aortic stiffness increases because the pressure wave, which travels from the heart to the periphery (during each cardiac cycle), is reflected at some point, ...
Review Article Heart failure with preserved ejection fraction
... early rapid filling phase begins. The peak early filling velocity is termed “E wave”, which is recorded with the deceleration time (DT) from peak to baseline at the end of the E wave. The LV pressure gradually increases until the LV and LA pressure has equalised. At this point the early filling phas ...
... early rapid filling phase begins. The peak early filling velocity is termed “E wave”, which is recorded with the deceleration time (DT) from peak to baseline at the end of the E wave. The LV pressure gradually increases until the LV and LA pressure has equalised. At this point the early filling phas ...
Pacing Concepts
... All the leads have the problem with child growth and results in high threshold, exit block, lead fracture. Even when a loop of lead was left in the pericardium, adhesions frequently formed that prevented unwinding of the loop. ...
... All the leads have the problem with child growth and results in high threshold, exit block, lead fracture. Even when a loop of lead was left in the pericardium, adhesions frequently formed that prevented unwinding of the loop. ...
Impact of age on QT interval and QT dispersion in healthy subjects
... Age did not have any impact on QTd in our study. QTd values were similar to the range of 30 and 60 ms that have been obtained previously in normal subjects [29]. Age-related differences -10 ms have been reported and appeared to be statistically significant in some larger studies. In the study from S ...
... Age did not have any impact on QTd in our study. QTd values were similar to the range of 30 and 60 ms that have been obtained previously in normal subjects [29]. Age-related differences -10 ms have been reported and appeared to be statistically significant in some larger studies. In the study from S ...
Sympathetic Innervation Alters Growth and Intrinsic Heart Rate of
... suggest that sympathetic innervation may influence both the growth and function of the developing heart. In contrast, other investigators suggest that inherent developmental processes determine the growth and functional characteristics of the young heart. Kirby and Stewart14 produced "sympatheticall ...
... suggest that sympathetic innervation may influence both the growth and function of the developing heart. In contrast, other investigators suggest that inherent developmental processes determine the growth and functional characteristics of the young heart. Kirby and Stewart14 produced "sympatheticall ...
a study on the echocardiography of the mitral valve in normal
... cases of MVP. In fact, the majority of people with MVP don’t have regurgitation and never have any symptoms or complications. In these people, even though the valve flaps prolapse, the valve is still able to form a tight seal. When regurgitation does occur, it can cause complications and troublesome ...
... cases of MVP. In fact, the majority of people with MVP don’t have regurgitation and never have any symptoms or complications. In these people, even though the valve flaps prolapse, the valve is still able to form a tight seal. When regurgitation does occur, it can cause complications and troublesome ...
Wearable Cardioverter Defibrillators - bcbsks.com
... (RCTs) of WCD compared with standard care or alternative treatments. RCTs of patients undergoing permanent implantable cardioverter defibrillator (ICD) implantation can provide indirect evidence on the efficacy of the WCD if the indications for a permanent ICD are similar to the potential indication ...
... (RCTs) of WCD compared with standard care or alternative treatments. RCTs of patients undergoing permanent implantable cardioverter defibrillator (ICD) implantation can provide indirect evidence on the efficacy of the WCD if the indications for a permanent ICD are similar to the potential indication ...
Hypertension and arrhythmia: blood pressure control
... interval, i.e. increased QT interval dynamicity, may facilitate the development of ventricular arrhythmias[40]. There is a paucity of data related to the association between hypertension and QT interval dynamicity. A study investigating the QT interval dynamics in hypertensive patients with or witho ...
... interval, i.e. increased QT interval dynamicity, may facilitate the development of ventricular arrhythmias[40]. There is a paucity of data related to the association between hypertension and QT interval dynamicity. A study investigating the QT interval dynamics in hypertensive patients with or witho ...
Congenital secundum atrial septal defect and
... diagnosed in a 1-day-old Holstein-Friesian calf necropsied in the Department of Pathology of Mehmet Akif Ersoy University. The secundum atrial septal defect was 32.9 × 23.1 mm in width and was elliptical. The membranous ventricular septal defect was 25.3 × 18.5 mm in width and was round to oval in s ...
... diagnosed in a 1-day-old Holstein-Friesian calf necropsied in the Department of Pathology of Mehmet Akif Ersoy University. The secundum atrial septal defect was 32.9 × 23.1 mm in width and was elliptical. The membranous ventricular septal defect was 25.3 × 18.5 mm in width and was round to oval in s ...
Restrictive Cardiomyopathy, Constrictive Pericarditis, and Cardiac
... The majority of contemporary cases of nonidiopathic constrictive pericarditis are caused by previous cardiac surgery, radiation exposure, and chronic pericarditis with a myriad of etiologies (31). With the increasing rates of patients undergoing cardiac surgery, the prevalence of constrictive perica ...
... The majority of contemporary cases of nonidiopathic constrictive pericarditis are caused by previous cardiac surgery, radiation exposure, and chronic pericarditis with a myriad of etiologies (31). With the increasing rates of patients undergoing cardiac surgery, the prevalence of constrictive perica ...
Normal anatomy and variations of sinoatrial nodal artery (SANA) in
... the subjects. In some, if heart rate could not be stabilized properly, then reconstructions were performed at 45% of R-R interval. The reconstructed images were interpreted with the help of a cardiac radiologist. Subjects with previous bypass surgery and also those with suboptimal study due to breat ...
... the subjects. In some, if heart rate could not be stabilized properly, then reconstructions were performed at 45% of R-R interval. The reconstructed images were interpreted with the help of a cardiac radiologist. Subjects with previous bypass surgery and also those with suboptimal study due to breat ...
Mitochondria as a Therapeutic Target in Heart Failure
... The 20th century has witnessed a dramatic improvement in patients’ survival after adverse cardiovascular events. However, heart disease still remains the number one cause of death in the industrialized world, affecting ⬎27 million people in the United States alone. With $40 billion in annual costs a ...
... The 20th century has witnessed a dramatic improvement in patients’ survival after adverse cardiovascular events. However, heart disease still remains the number one cause of death in the industrialized world, affecting ⬎27 million people in the United States alone. With $40 billion in annual costs a ...
but unusual neurological complication of the investigation
... A further case in which the diagnosis was confirmed by cardiac catheterization is here put on record. Angiography demonstrated an important alternative venous pathway carrying lower extremity blood to the superior vena cava by the azygos vein. The patient sustained an unfortunate but unusual neurolo ...
... A further case in which the diagnosis was confirmed by cardiac catheterization is here put on record. Angiography demonstrated an important alternative venous pathway carrying lower extremity blood to the superior vena cava by the azygos vein. The patient sustained an unfortunate but unusual neurolo ...
CLINICAL PROGRESS Velocity of Blood Flow in Health and Disease
... the consequent venous distention with the increased cross-section area of the flowing stream tends to slow the velocity of blood flow. In the heart, a number of factors influence the circulation time. Congenital cardiac anomalies with a significant right-to-left shunt usually produce a short circula ...
... the consequent venous distention with the increased cross-section area of the flowing stream tends to slow the velocity of blood flow. In the heart, a number of factors influence the circulation time. Congenital cardiac anomalies with a significant right-to-left shunt usually produce a short circula ...
Mitochondria as a Therapeutic Target in Heart Failure
... The 20th century has witnessed a dramatic improvement in patients’ survival after adverse cardiovascular events. However, heart disease still remains the number one cause of death in the industrialized world, affecting ⬎27 million people in the United States alone. With $40 billion in annual costs a ...
... The 20th century has witnessed a dramatic improvement in patients’ survival after adverse cardiovascular events. However, heart disease still remains the number one cause of death in the industrialized world, affecting ⬎27 million people in the United States alone. With $40 billion in annual costs a ...
Atrial Fibrillation - A Guide for Patients and Families
... Different types of heart conditions such as heart valve disease, heart attacks or heart failure can cause atrial fibrillation. Any type of infection that causes inflammation of the heart muscle or the outer layer of the heart may lead to atrial fibrillation. Some people who are born with heart probl ...
... Different types of heart conditions such as heart valve disease, heart attacks or heart failure can cause atrial fibrillation. Any type of infection that causes inflammation of the heart muscle or the outer layer of the heart may lead to atrial fibrillation. Some people who are born with heart probl ...
Evolution of Paroxysmal Atrial Fibrillation to Persistent or Permanent
... Introduction: Paroxysmal atrial fibrillation (PAF) eventually progresses to persistent and permanent AF. The predictors of progression from PAF to persistent and permanent AF are poorly understood. Methods: Electronic medical records of 437 patients with PAF were reviewed in a retrospective cohort s ...
... Introduction: Paroxysmal atrial fibrillation (PAF) eventually progresses to persistent and permanent AF. The predictors of progression from PAF to persistent and permanent AF are poorly understood. Methods: Electronic medical records of 437 patients with PAF were reviewed in a retrospective cohort s ...
Normal Ventricular Repolarization Dispersion Range with Abrupt
... Abnormal alterations in ventricular repolarization dispersion (VRD) have been shown to constitute a substrate for arrhythmias. In this work, we have induced abrupt heart rate (HR) changes to 17 healthy subjects through a Tilt-test Maneuver and have analyzed the evolution of several VRD indices. Dura ...
... Abnormal alterations in ventricular repolarization dispersion (VRD) have been shown to constitute a substrate for arrhythmias. In this work, we have induced abrupt heart rate (HR) changes to 17 healthy subjects through a Tilt-test Maneuver and have analyzed the evolution of several VRD indices. Dura ...
Myocardial infarction
Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the rupture of an atherosclerotic plaque, leading to complete blockage of a coronary artery. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.Worldwide, more than 3 million people have ST elevation MIs and 4 million have NSTEMIs each year. STEMIs occur about twice as often in men as women. About one million people have an MI each year in the United States. In the developed world the risk of death in those who have had an STEMI is about 10%. Rates of MI for a given age have decreased globally between 1990 and 2010.