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1 - JACC: Heart Failure
1 - JACC: Heart Failure

... among UNOS status 1A (adjusted hazard ratio [HR]: 1.20; 95% confidence interval [CI]: 1.05 to 1.37, p ¼ 0.01) after adjusting for more than 30 baseline variables. In contrast, female sex was significantly protective for time to death among UNOS status 2 patients (adjusted HR: 0.75; 95% CI: 0.67 to 0.8 ...
Development of the Heart
Development of the Heart

... pressure is higher in right atrium than in the left and highly oxygenayed blood flows directly from right atrium to left atrium through open foramen ovale. ...
3D multifunctional integumentary membranes for spatiotemporal
3D multifunctional integumentary membranes for spatiotemporal

... arrays. A thin, flexible heat-seal conductive cable (Elform, HST9805-210) serves as a connection to external hardware for data acquisition, power supply and control. The 3D-MIM is engineered with overall dimensions slightly smaller than those of the real heart, to provide adequate elasticity and mech ...
High Time-Resolved Cardiac Functional Imaging - MIP :: Lab
High Time-Resolved Cardiac Functional Imaging - MIP :: Lab

... magnetic resonance imaging is essential for longitudinal studies and for drug development related to cardiovascular diseases. Whereas dedicated small animal MR scanners are not readily available, it would be a great advantage to be able to perform cardiac assessment on clinical systems, in particula ...
PDF-1 - RUcore - Rutgers University
PDF-1 - RUcore - Rutgers University

... varies between maximum (systolic) pressure and a minimum (diastolic) pressure of the heart. During the cardiac cycle, systolic pressure is the maximum arterial pressure during peak ventricular ejection and the diastolic pressure is the minimum arterial pressure just before ventricular ejection begin ...
Cardiovascular System
Cardiovascular System

... Primitive Heart Regions: Differential growth of the endocardial tube establishes five primitive heart regions: 1] Truncus arteriosus — the output region of the heart. It will develop into the ascending aorta and pulmonary trunk. ...
Medical and Surgical Treatment of Acute Right Ventricular
Medical and Surgical Treatment of Acute Right Ventricular

... Inotropes improve cardiac contractility and CO by increasing cyclic adenosine monophosphate. Vasopressors increase RV perfusion pressure, thereby attenuating subendocardial ischemia. All inotropes concomitantly target the left ventricle (a desired effect in LV failure–induced RVF). Dobutamine, the i ...
No touch vein harvesting technique in coronary by-pass
No touch vein harvesting technique in coronary by-pass

... This thesis was based on a prospective randomized trial which was started in 1993 to compare the no touch (NT) with the conventional (C) technique of saphenous vein harvesting for CABG. In paper I, was demonstrated superior patency for the NT grafts at short-term (1.5 years; 95,6% vs 89%; p < 0,05) ...
Print - Circulation Research
Print - Circulation Research

... acutely induced cardiac hypertrophy were investigated in mature SpragueDawley rats. Special attention was given to the cellular organization of the growth process. Autoradiographic studies provided conclusive evidence that the uptake of tritiated thymidine is completely limited to nonmuscular cellul ...
Pre-participation screening in the young competitive athlete
Pre-participation screening in the young competitive athlete

... As summarized by a consensus paper that includes a 14-element evaluation process,7 the AHA recommends a car­ diovascular-focused personal history, family history, and physical examina­ ...
Cardiopulmonary Resuscitation (CPR) in Correctional Facilities
Cardiopulmonary Resuscitation (CPR) in Correctional Facilities

... I. The facts about CPR A. Heart disease is the number one killer in the United States. Each year, almost 330,000 Americans die from heart disease. Half of these will die suddenly, outside of the hospital, because their heart stops beating. B. The most common cause of death from a heart attack in adu ...
Clinical cardiac involvement in thrombotic
Clinical cardiac involvement in thrombotic

... studies described 398 total patients with TTP or HUS (6-220 total patients per article). Only 84 (22%) patients (1-32 patients per article, median 3 patients per article), however, were eligible for our analysis, because they appeared to have idiopathic TTP and they also had cardiac symptoms, testin ...
Hypertension in Children
Hypertension in Children

... Associate Professor of Pediatrics, University of Iceland Director of Pediatric Nephrology, Children´s Medical Center Landspitali - The National University Hospital of Iceland Reykjavik, Iceland ...
It Takes “Heart” to Win: What Makes the Heart Powerful?
It Takes “Heart” to Win: What Makes the Heart Powerful?

... function of [Ca2+] in permeabilized myocyte preparations (Ref. 9 and Fig. 2). In these studies, peak absolute power output increased more than fivefold as Ca2+ activation levels increased from ~30 to 100%. This increase in power was due to both an increase in force and an increase in velocity of sho ...
this PDF file
this PDF file

... are major criteria in the definition of arrhythmogenic cardiomyopathy very well characterising conduction delay of the right ventricle. Another clue for ECG definition is QRS fragmentation is all leads including “pre-silons” (QRS fragmentation in the Q wave), “topsilons” (QRS fragmentation in the R ...
Document
Document

... Clinical Picture • Very slow rate and abnormal pacemaker site severely impair cardiac output • Patients will frequently be unconscious from poor perfusion • Cardiac failure can follow quickly Gail Walraven, Basic Arrhythmias, Seventh Edition ©2011 by Pearson Education, Inc., Upper Saddle River, NJ ...
PDF - Circulation: Heart Failure
PDF - Circulation: Heart Failure

... Early disease with ATTRmt may be minimally symptomatic, especially compared with AL amyloidosis. Patients may complain of mild exercise intolerance or manifest arrhythmias. Clinical and imaging findings may be attributed to other causes of left ventricular hypertrophy and delay diagnosis, whereas mo ...
Pulmonary Valve
Pulmonary Valve

... neural crest cells from the brachial arches  Valves (Semilunar) have 3 equal cusp-shaped leaflets  Aortic valve incorporates coronary arteries  Atrioventricular (AV) valves = mitral and tricuspid  Final valves derived entirely from endocardial cushion tissue  Leaflet formed without a cusp ...
Implantable Cardioverter Defibrillator (ICD)
Implantable Cardioverter Defibrillator (ICD)

... ventricular ejection fraction (LVEF) and in patients who are recovering from acute myocardial infarction (MI). Although significant effort has been directed to the identification and treatment of high-risk patients, this group actually accounts for a small proportion of preventable SCD. Although the ...
WATCHMAN® Left Atrial Appendage Closure Device
WATCHMAN® Left Atrial Appendage Closure Device

Induction of cardiac muscle differentiation in isolated
Induction of cardiac muscle differentiation in isolated

... Using PCR primers derived from a comparison of vertebrate MHC sequences in the EMBL database, we amplified a 222 nucleotide fragment from adult heart cDNA, using the 3′ RACE procedure (Frohman et al., 1988). Sequencing revealed that this fragment comprises the final 37 carboxy-terminal residues of a ...
the value of right ventricular systolic and diastolic parameters to
the value of right ventricular systolic and diastolic parameters to

... Background: Along with left ventricular dysfunction as a powerful prognostic marker in patients with heart failure, right ventricular dysfunction has been shown to be a powerful determinant for early and late mortality and morbidity. There is still uncertain the best echocardiography parameters for ...
Pericardial Effusions and Cardiac Tamponade
Pericardial Effusions and Cardiac Tamponade

...  Irritation to diaphragm and phrenic nerve.  Highest risk of liver injury  Possibility of colon or stomach perforation ...
the mechanism of cardiac shunting in reptiles: a new synthesis
the mechanism of cardiac shunting in reptiles: a new synthesis

... intracardiac shunting in reptiles are controversial (Heisler et al. 1983; Heisler and Glass, 1985; Hicks and Malvin, 1992; Hicks and Comeau, 1994; Hicks, 1994), but two principal hypotheses termed pressure shunting and washout shunting have been put forward (Heisler and Glass, 1985). The pressure sh ...
Thermodynamic analysis questions claims of improved cardiac
Thermodynamic analysis questions claims of improved cardiac

... supporting evidence. The second thread is the more recent claim that a diet high in omega-3 fish oils can dramatically increase the pumping efficiency of the left ventricle, either by increasing its capacity for external work, with little or no change of oxygen consumption, or by a minimal effect on ...
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Myocardial infarction



Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the rupture of an atherosclerotic plaque, leading to complete blockage of a coronary artery. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.Worldwide, more than 3 million people have ST elevation MIs and 4 million have NSTEMIs each year. STEMIs occur about twice as often in men as women. About one million people have an MI each year in the United States. In the developed world the risk of death in those who have had an STEMI is about 10%. Rates of MI for a given age have decreased globally between 1990 and 2010.
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