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C03 Blood pressure assessment
C03 Blood pressure assessment

... White Coat Hypertension (WCH) is a phenomenon where normotensive individuals become hypertensive during assessment by a health professional, with pressures returning to normal outside of the medical environment. The phenomenon is reported to occur in as many as 15% to 30% of the population, although ...
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Therapeutic dimensions of ACE inhibitors- A review of literature Review Article
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... grafting. Some patients are at low risk, and others do not have lesions amenable to intervention. For these patients optimization of pharmacotherapy, in combination with lifestyle changes, is indicated. Many patients are adequately treated with a beta-blocker and nitrate alone. Beta-blockers are rec ...
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... Let’s follow a droplet of blood through the blood vessels. When the droplet leaves the left __________ of the heart, it goes into the largest artery in the body. This artery is called the ___________. Soon after leaving the heart, this droplet travels down toward the legs. From here, the blood trave ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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