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Sacubitril/Valsartan (Entresto®) Key Information
Sacubitril/Valsartan (Entresto®) Key Information

... starting Sacubitril/Valsartan. Please ensure your patient no longer receives this medication. Prescribing records should be updated to reflect the fact that this drug is being prescribed and supplied by the hospital until you are otherwise notified. The following steps have been taken to ensure a sa ...
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... Please read through this sheet and make sure you are familiar with ALL terms you see!  *Make sure these terms are in your blue folder: tissue, organ, circulatory system, system, heart, respiratory system, diaphragm, lungs, trachea Heart Box Diagram – Be able to label the following: four parts of th ...
Chronic stable angina
Chronic stable angina

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Online Data Base Search for Authors and Keywords
Online Data Base Search for Authors and Keywords

... the observation that the use of high doses of nifedipine capsule (80 mg) in coronary artery disease may significantly increase mortality as compared to placebo [3]. As a consequence calcium channel blockers of the dihydropyridine type should only be used if they guarantee a slow onset of action with ...
Human Circulatory System - St. Dominic High School
Human Circulatory System - St. Dominic High School

... - thin walled and less elastic - NO muscle tissues - muscles surrounding the veins contract to squeeze blood through veins - One way valves – prevent backflow within the vein if the veins are defective the blood flows back and veins dilate (varicose veins) ...
Circulatory System EQ
Circulatory System EQ

... Then click on this Blue Box ...
Fetal Pig Dissection Review
Fetal Pig Dissection Review

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Fetal Pig Dissection Review

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Slide Set - American College of Cardiology

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The heart - circulatorysystem4E
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Coronary Artery Disease CAD: a global problem What is CAD

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Inside the Operating Room: Exploring Top Causes of Death in the
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... connected, or grafted, to the blocked coronary artery. › The grafted artery or vein bypasses (that is, goes around) the blocked portion of the coronary artery. › This creates a new path for oxygen-rich blood to flow to the heart muscle. ...
Chapter 9 – The Cardiovascular System Test
Chapter 9 – The Cardiovascular System Test

... b. capillary bed c. myocardium d. endocardium 11. The valve between the left atrium and left ventricle is called the a. pulmonary valve b. tricuspid valve c. mitral valve d. aortic valve 12. Blood from the lower part of the body, such as the legs, travels to the heart through the a. superior vena ca ...
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... Valves in veins and the heart ensure circulation of blood by preventing backflow There is a separate circulation for the lungs The heart beat is initiated by a group of specialized muscle cells in the right atrium called the sinoatrial node The sinoatrial node acts as a pacemaker The sinoatrial node ...
SYSTEMIC HYPERTENSION – Early clinical series of patients with
SYSTEMIC HYPERTENSION – Early clinical series of patients with

... APNEA (OSA) SYSTEMIC HYPERTENSION (high blood pressure) – Early clinical series of patients with OSA reported a high prevalence of systemic hypertension. However, these early series failed to account for co-morbid conditions that may also be associated with elevated arterial pressure, most notably o ...
Review on Aspirin to Treat and Prevent Heart Attacks and
Review on Aspirin to Treat and Prevent Heart Attacks and

... The Food and Drug Administration (U.S.) is proposing to let doctors prescribe aspirin for patients to take during suspected heart attacks. This new use of the drug is based on studies showing that taking as little as half a regular-strength aspirin tablet as soon as a heart attack is suspected and c ...
Atrial Fibrillation (AF)
Atrial Fibrillation (AF)

... The risk of stroke is assessed. Older individuals are at higher risk of stroke. Having other medical conditions like high blood pressure, congestive heart or diabetes, and various structural cardiac abnormalities all predict stroke, as does having previously had a stroke. Drug treatment will be used ...
Dealing with a modern
Dealing with a modern

... sored program of primary and secondary prevention, known as the North Karelia Project, was officially initiated in 1972. In contrast to epidemiologic interventions of the 19th and early 20th centuries, the Project would not draw on quarantines and military bureaucracy to deal with miasmata and conta ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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