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heart and blood vessels
heart and blood vessels

... pericardium. This cavity contains a watery fluid called pericardial fluid, which reduces friction and erosion of tissue between these membranes as the heart expands and contracts during a cardiac cycle. • If an inflammation of the inner most layer of pericardial sac develops, it is known as pericard ...
Cardiac Physiology – Control of Cardiac Output
Cardiac Physiology – Control of Cardiac Output

... – Predictions concerning the effects of changes in peripheral resistance are complex because both the cardiac and vascular function curves shift. – With increased peripheral resistance, the vascular function curve is moves counterclockwise. – The cardiac function curve is also shifted downward becau ...
Chronic heart failure in the elderly: a current medical problem
Chronic heart failure in the elderly: a current medical problem

... heart failure occurs more and more commonly in the elderly. In the USA approximately 80% of patients discharged from hospital with newly diagnosed heart failure are over 65 years of age, whereas 50% are over 75. The average 5­‑year mortality rate is about 50% in subjects with systolic dysfunction an ...
Coronary Circulation..
Coronary Circulation..

... Ca2+ diffuses down gradient into cell. ...
Exercise Stress Test - Progressive Medical Clinic
Exercise Stress Test - Progressive Medical Clinic

... In patients who cannot exercise adequately (e.g., achieve 85% of age-adjusted MPHR prior to radiopharmaceutical administration and for at least 1 minute following radiotracer administration; achieve 5 METS or 5 minutes total exercise time on a Bruce protocol), the radiotracer should not be injected ...
HEART FAILURE - MEDICINE DEPARTMENT of MMC
HEART FAILURE - MEDICINE DEPARTMENT of MMC

... concentration. Creatinine should be less than or equal to 2.5 mg/dL in men or less than or equal to 2.0 mg/dL in women and potassium should be less than 5.0 or renal ...
Methods and devices of blood pressure measurement
Methods and devices of blood pressure measurement

... • Korotkoff  sounds compared to invasive blood  pressure measurementt – Korotkoff IV is on average 8mm Hg above  the invasively measured diastolic blood  pressure – Korotkoff V is on average 2mm Hg above  Korotkoff V is on average 2mm Hg above the invasively measured diastolic blood  pressure ...
A4L Key Mrs Smith Major Body Systems
A4L Key Mrs Smith Major Body Systems

... in the second phase (electron transport chain) for a total energy production of 35-38 units of energy----about 19 or 20 times more than would have been produced with only anaerobic metabolism. 5. Does anaerobic metabolism stop during aerobic metabolism? no---anaerobic metabolism continues as long as ...
Vocabulary Definitions Handout
Vocabulary Definitions Handout

Human Circulatory System 1
Human Circulatory System 1

... properly, where in the body might circulation be affected the most? • Why is it important to have two separate pathways for circulation? • Describe some of the adaptations of the mammalian heart that allow it to be efficient and ...
Blood Circulation
Blood Circulation

... 4. Pressure in the cuff is gradually reduced until sounds are heard in the vessels. (stethoscope) (systolic pressure reading) 5. Pressure continues to be released until the sounds stop ...
18(4) Oct 05 for web.indd
18(4) Oct 05 for web.indd

... alter the focus of medicine from treatment toward prevention. In the late 1940s when the study began, the first and only symptom of cardiovascular disease was often coronary death. Prevention was essential. Another coincidental factor in the success of the Heart Study was the availability of the ele ...
circulation regulation
circulation regulation

... 1. each vascular bed responds only to its own needs; no coordination with the needs of other vascular beds 2. the compensation cannot return the pressures and cardiac output to normal Also, in cases like the example of left ventricular failure 3. all systemic vascular beds that do not participate in ...
CVS physiology – April 2012
CVS physiology – April 2012

... d. kidney endothelial cells are attenuated to form gaps called fenestrations 55. Which of these is not a Vitamin K dependent clotting factor? a. Factor IX b. Prothrombin c. Protein C d. Factor XII 56. Regarding circulatory changes in exercise which is true? a. fall in tissue pO2 and rise in pCO2 hel ...
Congestive Heart Failure
Congestive Heart Failure

... blood to the body. There are many causes of CHF in dogs. The two most common causes are mitral valve insufficiency (MVI) and dilated cardiomyopathy (DCM). Clinical signs vary depending on whether the dog has left- or right-sided heart failure. The most common symptoms are decreased stamina, coughing ...
MCQ 1
MCQ 1

... a) may be carried out by skeletal, smooth or cardiac muscle or by glands b) is not influenced by higher centres in the brain c) results from activity in at least two central nervous synapses in series d) may involve simultaneous contraction of some skeletal muscles and relaxation of others e) can be ...
Cardiac Muscle
Cardiac Muscle

... This is called automaticity or autorhythmicity. • The absolute refractory period is about 250 ms. This prevents tetanic contractions which would interfer with the heart’s ability to pump. ...
Morbid Obesity
Morbid Obesity

... Morbidly obese patients are classified according to area of main fat mass: Peripheral (Gynecoid) obesity: associated with degenerative joint disease and venous stasis in the lower extremities. Central (Android) obesity: associated with the highest risk of mortality related problems due to the “Metab ...
Blood Pressure and Flow Measurements - MRI
Blood Pressure and Flow Measurements - MRI

... Describes the physiology and pathology of cardiocvascular system ”Normal” values are 120 / 80 mmHg High values may lead to heart attack and strokes Low values may lead to low oxygen perfusion Almost all indirect methods rely on an occlusive cuff which is placed on the bracial artery. The actual meas ...
Young Scientist Program  Anatomy Teaching Team 
Young Scientist Program  Anatomy Teaching Team 

... Just  like  any  other  tissue  in  the  human  body  the  heart  needs  both  nutrients  and  oxygen  in  order  to  keep  its  cells  alive  and  well.    Being  that  the  heart  is  mainly  a  big  tough  muscle,  it  needs  a  lot  of  nutrients and oxygen in order to continue to work all day a ...
Blood Pressure and Flow Measurements
Blood Pressure and Flow Measurements

... Describes the physiology and pathology of cardiocvascular system ”Normal” values are 120 / 80 mmHg High values may lead to heart attack and strokes Low values may lead to low oxygen perfusion Almost all indirect methods rely on an occlusive cuff which is placed on the bracial artery. The actual meas ...
The Heart: Valves
The Heart: Valves

... are made on the pressure in large arteries  Systolic – pressure at the peak of ventricular contraction  Diastolic – pressure when ventricles relax ...
Acute Care Problems Case Studies 1 and 2
Acute Care Problems Case Studies 1 and 2

... Question 1: What is the most likely diagnosis for this patient and what are the criteria for the diagnosis? The patient’s symptoms, medications, social history, and physical examination lead to the differential diagnoses of pulmonary arterial hypertension, pulmonary embolism, right-sided heart failu ...
Document
Document

... 30.3 The Heart and Circulation • The heart has four chambers: two atria, two ventricles. • Valves in each chamber prevent backflow of blood. • Muscles squeeze the chambers in a powerful pumping ...
over view of circulatory system heart and vessels
over view of circulatory system heart and vessels

... OVER VIEW OF CIRCULATORY SYSTEM HEART AND VESSELS LEARNING OBJECTIVES At the end of thelecture the student should be able to know About organization of cardio vascular system About Components of cardio vascular system About location, external and internal structure of heart About different chambers ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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