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Oxygen therapy for acute myocardial infarction
Oxygen therapy for acute myocardial infarction

... Sebastián, Spain. 4 West Midlands Health Technology Assessment Collaboration, University of Birmingham, Birmingham, UK. 5 Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK ...
Atrial tachycardia
Atrial tachycardia

... AVRT: Catheter ablation of accessory pathway Radio frequency ablation of the accessory pathway is often indicated in patients with WPW who are at risk of sudden death due to atrial fibrillation with a rapid ventricular response via the bypass tract. Note the disappearance of the preexcitation delta ...
Indicator - American Heart Association
Indicator - American Heart Association

... Ischemic stroke patients with LDL>100, or LDL not measured, or on cholesterolreducer prior to admission, who are discharged on cholesterol reducing drugs. An elevated serum lipid level has been a well-documented risk factor for coronary artery disease (CAD). Recently, there has been an increased foc ...
Factors Associated With Major Bleeding Events
Factors Associated With Major Bleeding Events

... in hemoglobin level or required therapeutic (INR) range transfusion. The effect of rivaroxaban in stroke/systemic embolism prevention and safety was consistent across a broad range of patient baseline characteristics (1), suggesting that once-daily, fixed-dose rivaroxaban is an alternative to adjuste ...
Connexin 43 Expression in Human Hypertrophied Heart Due to
Connexin 43 Expression in Human Hypertrophied Heart Due to

... Only few data are available in humans. In left ventricular biopsies of patients with hypertrophic and ischemic heart disease, Cx43 was found to be reduced (Peters et al. 1993). However, it appears that chronic ischemia or the presence of ventricular scars rather than cellular hypertrophy itself was ...
Factors Associated With Major Bleeding Events
Factors Associated With Major Bleeding Events

... in hemoglobin level or required therapeutic (INR) range transfusion. The effect of rivaroxaban in stroke/systemic embolism prevention and safety was consistent across a broad range of patient baseline characteristics (1), suggesting that once-daily, fixed-dose rivaroxaban is an alternative to adjuste ...
SIHD_Slide_Set
SIHD_Slide_Set

... Many important clinical questions addressed in the guidelines do not lend themselves to clinical trials. Although randomized trials are unavailable, there may be a very clear clinical consensus that a particular test or therapy is useful or effective. *Data available from clinical trials or registri ...
atrial fibrillation - Heart and Stroke Foundation
atrial fibrillation - Heart and Stroke Foundation

... Medicine is used to slow the conduction of electrical impulses from the top chambers (atria) to the bottom chambers (ventricles) of the heart and prevent the ventricles from beating too fast. A slower heart beat gives the ventricles more time to relax and fill with blood. The rate control medicine o ...
6 Heart Sounds
6 Heart Sounds

... by sudden deceleration and dissipation of energy of the moving column of blood in the left ventricle, its intensity will depend on the energy imparted to that column of blood by the contracting ventricle. The level of energy imparted will depend on the degree of acceleration achieved by the contract ...
I IIa IIb III - Professional Heart Daily
I IIa IIb III - Professional Heart Daily

... Many important clinical questions addressed in the guidelines do not lend themselves to clinical trials. Although randomized trials are unavailable, there may be a very clear clinical consensus that a particular test or therapy is useful or effective. *Data available from clinical trials or registri ...
Impairment of coronary flow reserve in aortic stenosis
Impairment of coronary flow reserve in aortic stenosis

... the data previously reported in normal subjects (Fig. 4), as well as in AS patients after AVR (14, 19, 24, 51). In the absence of AS, the inlet coronary flow depicts a typical biphasic pattern (Fig. 4, top) and the systolic CBF (S) represents ⬃25% of total CBF (S⫹D). In the presence of AS, the systo ...
PDF, 122KB - Queensland Courts
PDF, 122KB - Queensland Courts

... connecting fluids to the PICC – check in chart for CXR report.” 15 This document makes no reference to subsequent X-rays being done. This was not the document that Mrs Coad recalls seeing. Mrs Coad was also shown Exhibit C7 which is the Holy Spirit Hospital Policy and Procedures Manual on PICC line ...
Estimation of left ventricular operating stiffness from - AJP
Estimation of left ventricular operating stiffness from - AJP

... suspended ventilation before cardiopulmonary bypass, during partial (1.5–2 l/min) cardiopulmonary bypass, and after surgery. Ventilation was suspended for at most 20–30 s at a time during which time data collection was performed. All patients had continuous routine oxygen saturation monitoring, and ...
CV/CV Surgery Booklet - MC5751-10
CV/CV Surgery Booklet - MC5751-10

... Saint Marys Hospital for prompt and effective reperfusion. Twentyone referral sites are now formally enrolled in this program. A similar protocol to facilitate triage, treatment, and referral of non-STEMI patients at these sites is also being developed. • A clinical protocol was introduced to rapidl ...
Cardiorespiratory Fitness, Physical Activity, and
Cardiorespiratory Fitness, Physical Activity, and

... and/or methodologies for measuring arterial properties. The strong associations between cardiorespiratory fitness and arterial stiffness largely mirror those reported in other population-based studies relating VO2max levels and arterial stiffness in younger32 and older adults17 as well as in smaller ...
Valsartan improves mitochondrial function in hearts
Valsartan improves mitochondrial function in hearts

The Anatomic Basis for High-Frequency Components in
The Anatomic Basis for High-Frequency Components in

... Except for Reynolds and co-workers14 in a recent study of patients with primary myocardial disease, most of the emphasis previously has been placed on a relationship between coronary artery disease and the appearance of notches and slurs of frequencies higher than that of the basic QRS complex.' 15 ...
Effects of Sodium Nitroprusside on Left Ventricular Diastolic
Effects of Sodium Nitroprusside on Left Ventricular Diastolic

... excluded. The study group thus obtained consisted of 11 patients, including 2 patients with hypertrophic cardiomyopathy, 5 patients with chronic mitral regurgitation due to rheumatic heart disease, 1 patient with acute mitral regurgitation due to bacterial endocarditis, 2 patients with aortic regurg ...
Heart rate variability and baroreflex sensitivity in subjects without
Heart rate variability and baroreflex sensitivity in subjects without

... variability (HRV) and baroreflex sensitivity (BRS) in a large random sample of subjects without evidence of heart disease, and to estimate the relation of heart rate behavior to age, sex and cardiovascular risk factors. Short-term HRV was analyzed from 15-minute periods of standardized recording in ...
Venous excess: a new approach to cardiovascular control and its
Venous excess: a new approach to cardiovascular control and its

... Because the ventricles increase their force of contraction with increasing volume, they embody an intrinsic integral feedback control mechanism, in that accumulating ventricular excess stimulates a larger stroke volume until equilibrium is reached (or congestive heart failure intervenes). Thus Starl ...
Augmented pressor and sympathetic responses to skeletal muscle
Augmented pressor and sympathetic responses to skeletal muscle

... Augmented BP responses have been observed even during moderate-intensity handgrip (38), a level of isometric forearm muscle contraction that is equivalent to many activities of daily living such as opening jars, or carrying groceries. This is important because repeated surges in BP throughout the da ...
CfE Higher Human Biology Unit 2: Physiology and
CfE Higher Human Biology Unit 2: Physiology and

... The testes are the male reproductive organs. They have two functions: 1. the production of sperm in the seminiferous tubules; 2. the production of testosterone in the interstitial cells, which are found between the seminiferous tubules. Each testis contains several intensely folded seminiferous tubu ...
the relationship between electrical and mechanical - Heart
the relationship between electrical and mechanical - Heart

... needle, and recording of pressures has been previously described (Cournand and Ranges, 1941; Cournand et al., 1944; and Bloomfield et al., 1946). In some instances a double lumen catheter was used (Cournand et al., 1945), permitting the simultaneous recording of pressures in the right auricle and ve ...
Higher Human Biology Physiology and Health
Higher Human Biology Physiology and Health

... The testes are the male reproductive organs. They have two functions: 1. the production of sperm in the seminiferous tubules; 2. the production of testosterone in the interstitial cells, which are found between the seminiferous tubules. Each testis contains several intensely folded seminiferous tubu ...
Isolated Ventricular Systolic Interaction During
Isolated Ventricular Systolic Interaction During

... define the control beat, which was then subtracted from the unloaded beat. The resulting differences in pressure (as a function of time) were then used to calculate the instantaneous gain. Because of heart rate differences between animals, the period of systole was normalized such that the time from ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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