177 - Yamamoto et al. - Daniel Burkhoff MD PhD
... Transmyocardial laser revascularization (TMR) is a new therapy being evaluated to treat patients with refectory angina not amenable to traditional therapies (1). Clinical studies of TMR have shown an average two-class reduction in angina (2–4). In addition, results of some nuclear flow studies have ...
... Transmyocardial laser revascularization (TMR) is a new therapy being evaluated to treat patients with refectory angina not amenable to traditional therapies (1). Clinical studies of TMR have shown an average two-class reduction in angina (2–4). In addition, results of some nuclear flow studies have ...
Obstructive Sleep Apnea and Cardiovascular Disease
... (i.e., age, sex, race, smoking, alcohol consumption, body mass index, and the presence or absence of diabetes mellitus, dyslipidemia, atrial fibrillation, and hypertension).5 This finding is consistent with a cross-sectional study showing that patients with an apnea hypopnea index (AHI) ≥ 20 had sig ...
... (i.e., age, sex, race, smoking, alcohol consumption, body mass index, and the presence or absence of diabetes mellitus, dyslipidemia, atrial fibrillation, and hypertension).5 This finding is consistent with a cross-sectional study showing that patients with an apnea hypopnea index (AHI) ≥ 20 had sig ...
Geriatric Cardiology – You CAN treat Angina! Part 1
... * Gated wall motion analysis is performed, and shows normal wall motion with rest LVEF of 65% and post stress LVEF of 61%. *** Conclusions *** The patient had a possible anginal symptom during exercise in the absence of SPECT evidence of ischemia at a heart rate of 110/min. ...
... * Gated wall motion analysis is performed, and shows normal wall motion with rest LVEF of 65% and post stress LVEF of 61%. *** Conclusions *** The patient had a possible anginal symptom during exercise in the absence of SPECT evidence of ischemia at a heart rate of 110/min. ...
Constrictive pericarditis in rheumatoid arthritis
... that may persist for years,'2 and the pericardial rheumatoid pericarditis.19 effusion and murmur may be recurrent and evanIt is difficult to be certain how common pericardiescent. This was shown by our patient No 2, where tis is in rheumatoid arthritis, let alone how often it the rub was heard only ...
... that may persist for years,'2 and the pericardial rheumatoid pericarditis.19 effusion and murmur may be recurrent and evanIt is difficult to be certain how common pericardiescent. This was shown by our patient No 2, where tis is in rheumatoid arthritis, let alone how often it the rub was heard only ...
Ryanodine receptors | SpringerLink
... Excitation-contraction coupling involves the faithful conversion of electrical stimuli to mechanical shortening in striated muscle cells, enabled by the ubiquitous second messenger, calcium. Crucial to this process are ryanodine receptors (RyRs), the sentinels of massive intracellular calcium stores ...
... Excitation-contraction coupling involves the faithful conversion of electrical stimuli to mechanical shortening in striated muscle cells, enabled by the ubiquitous second messenger, calcium. Crucial to this process are ryanodine receptors (RyRs), the sentinels of massive intracellular calcium stores ...
2014 AHA/ACC/HRS Guideline for the€Management of
... guideline for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol 2014;64:2246–80. This article is copublished in Circulation ...
... guideline for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol 2014;64:2246–80. This article is copublished in Circulation ...
Cardiac Alpha1-Adrenergic Receptors
... the IP3-receptor to release calcium from intracellular stores, and DAG activates protein kinase C (PKC). Other Gq-coupled GPCRs that signal through Gaq, such as endothelin receptors (ETRs) and angiotensin receptors (ATRs), are believed to play an important role in the pathogenesis of heart failure. ...
... the IP3-receptor to release calcium from intracellular stores, and DAG activates protein kinase C (PKC). Other Gq-coupled GPCRs that signal through Gaq, such as endothelin receptors (ETRs) and angiotensin receptors (ATRs), are believed to play an important role in the pathogenesis of heart failure. ...
Nitroglycerin in 5% Dextrose Injection, USP
... patients receiving intravenous nitroglycerin, concomitant heparin therapy should be guided by frequent measurement of the activated partial thromboplastin time. ...
... patients receiving intravenous nitroglycerin, concomitant heparin therapy should be guided by frequent measurement of the activated partial thromboplastin time. ...
Effect of Mechanical Assist Devices for Ischemic Myocardial Damage
... weaning protocols have yet to be determined. Features of apoptosis include nuclear changes accompanying a half-moon-like or horseshoe-like condensation of chromatin, cytoplasmic shrinkage, and apoptosis body. It has been tacitly believed that apoptosis does not occur in terminally differentiated adu ...
... weaning protocols have yet to be determined. Features of apoptosis include nuclear changes accompanying a half-moon-like or horseshoe-like condensation of chromatin, cytoplasmic shrinkage, and apoptosis body. It has been tacitly believed that apoptosis does not occur in terminally differentiated adu ...
Congestive Heart Failure Educational Handbook
... As heart failure gets worse, the heart attempts to make up for lost pumping power. This may cause changes in the shape of the heart and result in an uncoordinated heartbeat, which is called an arrhythmia (a rhythm that is not normal). Although heart failure cannot be cured, there are many things tha ...
... As heart failure gets worse, the heart attempts to make up for lost pumping power. This may cause changes in the shape of the heart and result in an uncoordinated heartbeat, which is called an arrhythmia (a rhythm that is not normal). Although heart failure cannot be cured, there are many things tha ...
Dietary Salt Restriction Improves Cardiac and Adipose Tissue
... lowering blood pressure in individuals with several risk factors for MetS.6 In contrast, several surveys demonstrated an inverse association of cardiovascular mortality with salt intake.12–14 The relation between cardiovascular mortality and salt intake is still controversial, and the effects of die ...
... lowering blood pressure in individuals with several risk factors for MetS.6 In contrast, several surveys demonstrated an inverse association of cardiovascular mortality with salt intake.12–14 The relation between cardiovascular mortality and salt intake is still controversial, and the effects of die ...
the PDF - Heart Rhythm Society
... markers have been correlated with total rather than arrhythmic mortality. Although extensive comparative data are not available, when examined in the same population with other risk markers T wave alternans appear to predict SCD-related events with greatest negative predictive value49 –51, suggestin ...
... markers have been correlated with total rather than arrhythmic mortality. Although extensive comparative data are not available, when examined in the same population with other risk markers T wave alternans appear to predict SCD-related events with greatest negative predictive value49 –51, suggestin ...
Evaluation of Melissa officinalis (Lemon Balm) Effects on Heart
... Background: Melissa officinalis, an herbal drug, is well known and frequently applied in traditional and modern medicine. Yet, there is inadequate information regarding its effects on electrical properties of the heart. The present study attempted to elucidate the effects of Melissa officinalis aque ...
... Background: Melissa officinalis, an herbal drug, is well known and frequently applied in traditional and modern medicine. Yet, there is inadequate information regarding its effects on electrical properties of the heart. The present study attempted to elucidate the effects of Melissa officinalis aque ...
Acutely Decompensated Heart Failure: Diagnostic and Therapeutic
... have contributed data on the epidemiology, diagnosis, and treatment of ADHF. The Acute Decompensated Heart Failure National Registry is a registry of medical information from patients with ADHF from over 275 hospitals.4 Results from this registry have confirmed the high prevalence of underlying como ...
... have contributed data on the epidemiology, diagnosis, and treatment of ADHF. The Acute Decompensated Heart Failure National Registry is a registry of medical information from patients with ADHF from over 275 hospitals.4 Results from this registry have confirmed the high prevalence of underlying como ...
Corporate Medical Policy
... comparison of multiple models have documented relatively poor performance, with inability to predict central nervous system events. In a study of 79,884 patients followed for an average of 4 years, risk prediction models were found to have only modest discriminatory ability, with C-statistics of app ...
... comparison of multiple models have documented relatively poor performance, with inability to predict central nervous system events. In a study of 79,884 patients followed for an average of 4 years, risk prediction models were found to have only modest discriminatory ability, with C-statistics of app ...
Right ventricular remodeling and function in pulmonary arterial hypertension
... During the last decade, multiple medical therapies (i.e. prostacyclins, endothelin receptor antagonists, phosphodiesterase five inhibitors) have been developed that have mainly pulmonary vasodilator effects resulting in reduced PVR and improved CO35,36. These therapies have contributed to a more sta ...
... During the last decade, multiple medical therapies (i.e. prostacyclins, endothelin receptor antagonists, phosphodiesterase five inhibitors) have been developed that have mainly pulmonary vasodilator effects resulting in reduced PVR and improved CO35,36. These therapies have contributed to a more sta ...
Acute myocardial infarction in patients with ST segment elevation
... of assisting physicians in selecting the best management strategies for an individual patient with a given condition, taking into account the impact on outcome, as well as the risk –benefit ratio of particular diagnostic or therapeutic means. Guidelines are not ...
... of assisting physicians in selecting the best management strategies for an individual patient with a given condition, taking into account the impact on outcome, as well as the risk –benefit ratio of particular diagnostic or therapeutic means. Guidelines are not ...
Diet, Hypertension and Salt Toxicity
... physiological stress may do irreparable harm to the body, the most obvious being increased blood pressure and dramatically increased risk of cardiovascular events. Is there sufficient scientific research to justify telling all Americans to cut back on salt? If so by how much should salt intake be re ...
... physiological stress may do irreparable harm to the body, the most obvious being increased blood pressure and dramatically increased risk of cardiovascular events. Is there sufficient scientific research to justify telling all Americans to cut back on salt? If so by how much should salt intake be re ...
AHA Scientific Statement
... Electrode placement should be in a modified version of the Mason-Likar placement, with the arm leads at the lateral and superior corners of the sternum and the leg electrodes near the right and left inferior rib margins between the midclavicular and anterior axillary lines. In patients undergoing ex ...
... Electrode placement should be in a modified version of the Mason-Likar placement, with the arm leads at the lateral and superior corners of the sternum and the leg electrodes near the right and left inferior rib margins between the midclavicular and anterior axillary lines. In patients undergoing ex ...
Cardiovascular manifestations of renovascular hypertension
... to 50% of end stage renal disease cases in developed countries (Tuttle et al., 2014). In addition to increased risk for myocardial infarction and stroke, patients with diabetes are prone to develop a diabetic cardiomyopathy, characterized by extensive fibrotic changes and cardiomyocyte hypertrophy, ...
... to 50% of end stage renal disease cases in developed countries (Tuttle et al., 2014). In addition to increased risk for myocardial infarction and stroke, patients with diabetes are prone to develop a diabetic cardiomyopathy, characterized by extensive fibrotic changes and cardiomyocyte hypertrophy, ...
ESC Guidelines on ST segment elevation acute myocardial
... of assisting physicians in selecting the best management strategies for an individual patient with a given condition, taking into account the impact on outcome, as well as the risk –benefit ratio of particular diagnostic or therapeutic means. Guidelines are not ...
... of assisting physicians in selecting the best management strategies for an individual patient with a given condition, taking into account the impact on outcome, as well as the risk –benefit ratio of particular diagnostic or therapeutic means. Guidelines are not ...
Original Article MRI shows limited mixing between systemic and
... Each of the four transposition foetuses underwent emergency balloon atrial septostomy at birth followed by an arterial switch operation in the neonatal period. Of the four patients, three made rapid progress and had no residual lesions or significant morbidity at 1 year of age. Transposition subject ...
... Each of the four transposition foetuses underwent emergency balloon atrial septostomy at birth followed by an arterial switch operation in the neonatal period. Of the four patients, three made rapid progress and had no residual lesions or significant morbidity at 1 year of age. Transposition subject ...
Photoplethysmography and its application in clinical
... The wavelength of optical radiation is also important in light–tissue interactions (Cui et al 1990), and for three main reasons: (1) The optical water window: the main constituent of tissue is water that absorbs light very strongly in the ultraviolet and the longer infrared wavelengths. The shorter ...
... The wavelength of optical radiation is also important in light–tissue interactions (Cui et al 1990), and for three main reasons: (1) The optical water window: the main constituent of tissue is water that absorbs light very strongly in the ultraviolet and the longer infrared wavelengths. The shorter ...
Muscle Metaboreflex Control Of Coronary Blood Flow And
... maintain proper blood pressure levels and thus an increase in central blood mobilization (97). It appears these processes all occur in order to increase blood pressure and flow to ischemic muscles. A study by Joyner (45) done in humans, and another by Mittelstadt et al. (70) have shown that even the ...
... maintain proper blood pressure levels and thus an increase in central blood mobilization (97). It appears these processes all occur in order to increase blood pressure and flow to ischemic muscles. A study by Joyner (45) done in humans, and another by Mittelstadt et al. (70) have shown that even the ...
Antihypertensive drug
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.